JPH0236261B2 - - Google Patents

Description

[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to a drug storage container, and particularly to a solute container that is stored in a storage chamber and contains a solute such as a powdered or liquid drug. The present invention relates to a drug storage container that can aseptically dissolve solutes such as powdered or liquid drugs by sending a solvent such as a solution in a storage chamber.

[Conventional technology]

Many drugs (solutes) are dissolved in a solution (solvent) just before being injected intravenously into a patient. There are various reasons for this, but a typical one is that once a drug is dissolved in a solution, its effectiveness can only be maintained for a short period of time. For this reason, conventionally, when administering powdered drugs such as antibiotics stored in a solute container to a patient, aspirate an appropriate amount of a solution such as physiological saline or 5% glucose injection using a syringe, and then administer the powdered drug. The needle of the syringe was inserted into the solute container containing the solute, a solution was injected, and after dissolving the powdered drug, it was aspirated again with the syringe and injected into the patient.

In addition, the solute container containing the powdered drug and the bag containing the dissolution solution are connected aseptically using an adapter (communicating section) that holds a piercing needle and a broken part, and the dissolution solution is transferred. The solution was injected into a solute container containing a powdered drug to dissolve the powdered drug, and the solution was returned to the bag and administered intravenously to the patient. (Refer to Japanese Patent Publication No. 59-500600) Furthermore, it is composed of a solute container containing a powdered drug, a bag containing a dissolving solution, and an empty bag, and these are connected to each other by an adapter having a needle or a broken part. The solution is put into the solute container and the powdered drug is dissolved. At this time, the empty bag is used as an air vent to completely dissolve the antibiotic, etc., and this solution is put back into the bag. The patient was then given an intravenous drip. (U.S. Patent No.
4484920).

[Problem that the invention seeks to solve]

However, in the conventional case as described above, after dissolution, a syringe and a container containing the powdered drug must be prepared separately, and these operations must be carried out in a clean bench or other facility where sterile work can be performed. There are also complications in operation and the risk of bacterial contamination from the outside. In addition, although sterile equipment such as a clean bench is not required in this case, there are cases where the solute container containing the powdered drug and the adapter are connected incorrectly, the connection operation is complicated, and the structure of the adapter is complicated. There is a problem. In further cases, the solute container containing the powdered drug and the adapter are connected incorrectly, or the liquid containing the powdered drug is poured into an empty bag, and the operation of returning the liquid to the bag containing the solution may be necessary. There were problems such as not being easy.

Therefore, the present invention was made in view of the above circumstances, and although it has a simple structure, it is capable of dissolving powdered drugs such as antibiotics in an aseptic manner. To provide a drug storage container that does not enter a solute container containing a drug and is easy to operate.

[Means for solving problems]

In order to solve the above-mentioned problems, the drug storage container of the present invention has a storage chamber having a discharge port and a solvent sealed therein, and contains a solute to be dissolved by the solvent, and can be pierced by a piercing needle. a solute container having a piercing portion; a piercing needle interposed between the storage chamber and the solute container and capable of piercing the piercing portion of the solute container when necessary; and a piercing needle located within the storage chamber when necessary. a communication part that is separable and includes a closing part that communicates with the piercing needle when separated, and a piercing part of the solute container and the piercing needle are connected at a predetermined interval; a guide cover that plastically deforms in the axial direction of the piercing needle when an external force of a predetermined amount or more is applied, the piercing needle is inserted into the piercing portion of the solute container, and the separable closing portion By separating the storage chamber and the solute container, the storage chamber and the solute container are configured to communicate with each other.

[Function] According to the above configuration, the piercing needle of the communicating portion in a sealed state is inserted into the piercing portion of the container by plastically deforming the guide cover in the axial direction of the piercing needle using an external force of a predetermined amount or more,
separating the separable blockage, injecting the solvent in the reservoir into the solute container, dissolving the solute in the solute container, and returning the solute container back into the reservoir;
This solution is supplied to others through the outlet.

[Example] Hereinafter, an example of the present invention will be described in detail based on the accompanying drawings.

FIG. 1 is a perspective view of a drug storage container of the present invention covered with a packaging material, and FIG. 2 is a perspective view of the drug storage container. In both figures, reference numeral 1 denotes a drug storage container, and the drug storage container 1 is formed by integrally molding a storage chamber 2 and a storage chamber 3, which are independent from each other, from a flexible synthetic resin sheet. This drug storage container 1 is
The whole is covered with a rectangular packaging material 4, and the stability of the solution (solvent) S, which will be described later, sealed in the storage chamber 2 is guaranteed by this packaging material 4. In the storage chamber 2, 50 to 100 ml of a dissolving solution S, such as physiological saline or 5% glucose solution, is sealed. In FIG. 2, a discharge port 5 is provided at the lower part of the storage chamber 2, and the discharge port 5 is further covered with an aluminum cap 6 to prevent the solution S from coming out. Between the upper part of the storage chamber 2 and the lower part of the storage chamber 3, a broken part (separable closing part) 7 is located in the storage chamber 2, and a bottle is located in the storage chamber 3 at the tip. A communication portion 9 having a needle (piercing needle) 8 is provided. This bottle needle 8 is provided with a turning blade 8a, and is difficult to come out after being pierced once. A vial (solute container) 10 made of glass or resin is stored in the storage chamber 3, and a powdered antibiotic (solute) A is contained in the vial 10. A rubber stopper (piercing portion) 11 through which the bottle needle 8 described above can be inserted is fitted into the opening 10a of the vial 10. Further, a bellows (guide cover) 12 is provided between the opening 10a of the vial 10 and the bottom 3a of the storage chamber 3 in FIG. This jiyabara 1
2 is a material that plastically deforms when a predetermined force or more is applied in the axial direction, that is, in the direction in which the bottle needle 8 of the communication portion 9 pierces the rubber stopper 11 fitted into the opening 10a of the vial 10, such as aluminum; It is made of polypropylene or the like. For this reason, unless a force exceeding a predetermined value is applied in the axial direction, the bottle needle 8
1 is not pierced, and the solution S does not enter the vial 10 by mistake. Further, the bottle needle 8 is guided by this bellows 12, and prevents the bottle needle 8 from accidentally penetrating anything other than the rubber stopper 11.

A hole 1a is bored in the upper part of the drug storage container 1, and the drug storage container 1 is hung on a hanger 14 of an infusion stand 13 as shown in FIG. 3d.

The storage chamber 2 of the drug storage container 1 is connected to the patient M by an infusion set 15.
is an aluminum cap 6 placed over the discharge port 5.
The bottle needle 16 that pierces the bottle, the octopus tube 17 and the cleanser 1
8 and an intravenous needle 19 inserted into a blood vessel or the like of patient M,
It consists of a tube 20 that connects these. That is, by piercing the bottle needle 16 of the infusion set 15 into the aluminum cap 6 placed over the discharge port 5 of the storage tank 2, the reservoir chamber 2 can be used to supply the infusion set 15 to the patient M.
connected via.

Next, a method of using the drug storage container 1 having the above structure will be described.

First, vial 1 stored in storage chamber 3
The bottle needle 8 of the communicating part 9 is pierced through the rubber stopper 11 fitted into the mouth 10a of the bottle by plastically deforming the bellows 12 in the axial direction with an external force of a predetermined amount or more (see FIG. 3a);
Furthermore, the broken part 7 of the communicating part 9 is broken, and the vial 1 is removed.
0 and the storage chamber 2 are communicated with each other via the communication portion 9 (see FIG. 3b). Next, the solution S sealed in the storage chamber 2 is injected into the vial 10 through the communication part 9 with the storage chamber 2 facing up and the vial 10 facing down. Dissolve substance A (see Figure 3C). A solution containing powdered antibiotic A is returned to the storage chamber 2 with the vial 10 facing up and the storage chamber 2 facing down. The above-described operation is repeated to completely dissolve the powdered antibiotic A in the vial 10. Then, the packaging material 4 covering this drug storage container 1 is removed, and the hole 1 of this drug storage container 1 is removed.
a through the hanger 14 of the infusion stand 13,
Hang the drug storage container 1 on the hanger 14 (Fig. 3d)
reference). That is, the drug storage container 1 is hung on the hanger 14 with the storage chamber 2 containing the solution containing the dissolved antibiotic A in powder form facing down. After that, insert the intravenous needle 19 of the infusion set 15 into the blood vessel of the patient M, remove the aluminum cap 6 that covers the outlet 5, insert the bottle needle 16 into the outlet 5, and adjust the clamp 18. A solution in which powdered antibiotic A is dissolved in the storage chamber 2 of the medicine storage container 1 is intravenously injected into the patient A.

FIG. 4 shows another embodiment of the present invention, which has substantially the same configuration as the embodiment shown in FIG. 2, so the same parts are given the same symbols and the explanation thereof will be omitted. In the embodiment shown in FIG. 2, the drug storage container 1 has a storage chamber 2 and a storage chamber 3 that are independent of each other and are integrally molded from a flexible synthetic resin sheet. 2 and the storage chamber 3' are separate bodies. The storage chamber 3' has a cylindrical shape with a bellows-shaped outer peripheral surface. A hanger 21 is attached to the end face of this storage chamber 3'.
The other structural functions are the same as those of the embodiment shown in FIG. 2, so a description thereof will be omitted.

〔Effect of the invention〕

As described in detail above, the drug storage container of the present invention has a storage chamber which has a discharge port and is filled with a solvent, and which accommodates a solute to be dissolved by the solvent and which can be penetrated by a piercing needle. a solute container having a piercing portion, interposed between the storage chamber and the solute container,
and comprises a piercing needle that can penetrate the piercing part of the solute container when necessary, and a closing part that is located within the storage chamber and can be separated when necessary, and is in communication with the piercing needle when separated. connecting a communicating portion, a piercing portion of the solute container, and the piercing needle at a predetermined interval;
The guide cover is provided with a guide cover that plastically deforms in the axial direction of the piercing needle when an external force of a predetermined amount or more is applied, and guides the piercing needle of the communicating part in a sealed state to the piercing part of the container by an external force of a predetermined amount or more. The cover is pierced by plastic deformation in the axial direction of the piercing needle, the separable blocking part is separated, and the solvent in the storage chamber is injected into the solute container to dissolve the solute in the solute container. This solution is returned to the storage chamber, and this solution is supplied to others through the outlet in the storage chamber.

Therefore, the drug container of the present invention has a simple structure because it has a small number of components, and the communication part is sealed so that it is sterile, and furthermore, an external force in the axial direction that exceeds a predetermined value is not applied to the guide cover. Since the guide cover is not plastically deformed, the piercing needle of the communication portion hardly pierces the piercing portion of the solute container. Moreover, since there are no empty bags, the melting operation is easy.

[Brief explanation of drawings]

1 to 3 show an embodiment of the present invention,
Figure 1 is a perspective view of the medicine storage container covered with packaging material, Figure 2 is an enlarged perspective view of the medicine storage container in Figure 1 with the packaging material removed, and Figure 3 is the medicine storage container. FIG. 4 is a perspective view of a drug storage container showing another embodiment of the present invention. DESCRIPTION OF SYMBOLS 1... Drug storage container, 2... Storage chamber, 5... Outlet, 7... Broken part (separable closing part), 8...
... Bottle needle (piercing needle), 9 ... Communication part, 10 ... Vial (solute container), 11 ... Rubber stopper (piercing part), 1
2...Jiyabara (guide cover), S...Solution solution (solvent), A...Antibiotic (solute).

Claims (1)

[Claims] 1. A storage chamber having a discharge port and containing a solvent therein, a solute container containing a solute dissolved by the solvent and having a piercing portion that can be pierced by a piercing needle, and the storage chamber; A piercing needle interposed between the solute container and capable of piercing the piercing portion of the solute container when necessary, and a piercing needle located within the storage chamber and separable when necessary, and when separated, the piercing needle A communication part consisting of a closed part that communicates with the piercing part of the solute container and the piercing needle are connected at a predetermined interval, and when an external force of a predetermined amount or more is applied, the piercing needle is moved in the axial direction of the piercing needle. a guide cover that is plastically deformed, and the storage chamber and the solute container are separated by piercing the piercing needle through the piercing portion of the solute container and separating the separable closing portion. A drug storage container configured to communicate with each other.