JP6898655B2 - Cosmetic composition - Google Patents
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- JP6898655B2 JP6898655B2 JP2018093506A JP2018093506A JP6898655B2 JP 6898655 B2 JP6898655 B2 JP 6898655B2 JP 2018093506 A JP2018093506 A JP 2018093506A JP 2018093506 A JP2018093506 A JP 2018093506A JP 6898655 B2 JP6898655 B2 JP 6898655B2
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- Cosmetics (AREA)
Description
本発明は、化粧料組成物に関する。 The present invention relates to a cosmetic composition.
乾燥肌、敏感肌、シミ、しわ、クマ、テカリ、くすみ等、肌の問題を改善するために、様々な美容成分を含む化粧品が市販されている。美容成分は、たとえば、コラーゲン、ヒアルロン酸、ビタミンC等である。 Cosmetics containing various beauty ingredients are commercially available to improve skin problems such as dry skin, sensitive skin, spots, wrinkles, bears, shine, and dullness. The cosmetological ingredients are, for example, collagen, hyaluronic acid, vitamin C and the like.
ここで、美容成分としてリンゴエキスを利用することが検討されている。リンゴエキスは、一般に、抗炎症効果、保湿効果、ピーリング効果、角質柔軟効果、抗酸化効果があるとされる。このようなリンゴエキスは、たとえば、石鹸、化粧水、美容液、化粧下地、日焼け止め、ピーリング剤等に使用することが可能である。 Here, the use of apple extract as a cosmetological ingredient is being studied. Apple extract is generally considered to have anti-inflammatory effect, moisturizing effect, peeling effect, keratin softening effect, and antioxidant effect. Such apple extracts can be used, for example, in soaps, lotions, beauty essences, makeup bases, sunscreens, peeling agents and the like.
リンゴエキスには、アルコール類を用いてリンゴの果実から抽出したエキスの他、リンゴの種子から採取した「リンゴ種子エキス」、或いは、特定のリンゴの幹細胞を培養して作られる「リンゴ果実幹細胞エキス」が知られている。 Apple extracts include extracts extracted from apple fruits using alcohols, "apple seed extracts" collected from apple seeds, or "apple fruit stem cell extracts" made by culturing specific apple stem cells. "It has been known.
ところで、一般的な化粧品には、保湿力の向上や、使用する際の扱いやすさ、或いは安定性を高めるために油分(鉱物油や油脂)が含まれる。 By the way, general cosmetics contain oils (mineral oils and fats and oils) in order to improve moisturizing power, ease of handling when used, and stability.
たとえば、特許文献1には、肌へののび、肌なじみ、べたつき感のなさ、エモリエント感、はり感、しわ・たるみ改善等の効果に優れる水中油型乳化皮膚化粧料が開示されている。具体的に、当該化粧料は、アセチル化ヒアルロン酸、特定のポリメタクリロイルオキシエチルホスホリルコリン誘導体、非乳化性架橋型シリコーン、グリセリン、ポリビニルアルコール、アクリルアミド系増粘剤、水中油型乳化皮膚化粧料全量に対して総量が25質量%以上の油分を含有する。 For example, Patent Document 1 discloses an oil-in-water emulsified skin cosmetic having excellent effects such as spreading on the skin, familiarity with the skin, non-stickiness, emollient feeling, swelling feeling, and improvement of wrinkles / sagging. Specifically, the cosmetics include acetylated hyaluronic acid, specific polymethacryloyloxyethyl phosphorylcholine derivatives, non-emulsifying crosslinked silicones, glycerin, polyvinyl alcohol, acrylamide thickeners, and oil-in-water emulsified skin cosmetics. On the other hand, the total amount of oil is 25% by mass or more.
ここで、特許文献1のように、美容成分と油分を含む化粧品を肌に使用した場合、油分による膜が肌上に形成される。その結果、肌の内部に美容成分が浸透し難くなり、美容成分が有する効果を十分に得られないという問題がある。 Here, when a cosmetic containing a beauty ingredient and an oil component is used on the skin as in Patent Document 1, a film due to the oil component is formed on the skin. As a result, it becomes difficult for the beauty ingredient to penetrate into the inside of the skin, and there is a problem that the effect of the beauty ingredient cannot be sufficiently obtained.
本発明の目的は、美容成分としてリンゴエキスを含み、美容成分が肌の内部に浸透しやすい化粧料組成物を提供することにある。 An object of the present invention is to provide a cosmetic composition containing an apple extract as a cosmetological ingredient and in which the cosmetological ingredient easily penetrates into the skin.
上記目的を達成するための主たる発明は、油分を含まない化粧料組成物であって、リンゴエキスを含む化粧料組成物である。
本発明の他の特徴については、本明細書の記載により明らかにする。
The main invention for achieving the above object is an oil-free cosmetic composition, which is a cosmetic composition containing an apple extract.
Other features of the invention will be clarified by the description herein.
本発明の化粧料組成物は、美容成分としてリンゴエキスを含み、美容成分が肌の内部に浸透しやすい。 The cosmetic composition of the present invention contains an apple extract as a beauty ingredient, and the beauty ingredient easily penetrates into the skin.
==実施形態==
本実施形態に係る化粧料組成物は、化粧品又は医薬部外品として利用される。本実施形態に係る化粧料組成物はリンゴエキスを含む。
== Embodiment ==
The cosmetic composition according to this embodiment is used as a cosmetic or a quasi-drug. The cosmetic composition according to this embodiment contains an apple extract.
本実施形態に係るリンゴエキスは、化粧料組成物の美容成分に相当する。リンゴエキスはリンゴを加工することにより得られる液体である。 The apple extract according to this embodiment corresponds to a cosmetological ingredient of a cosmetic composition. Apple extract is a liquid obtained by processing apples.
本実施形態に係るリンゴエキスは、ビタミン(ビタミンA、ビタミンE、ビタミンB1、ビタミンB2、ナイアシン、ビタミンB6、葉酸、パントテン酸、ビタミンC、カロテン)、無機質(カリウム、カルシウム、マグネシウム、リン、銅、マンガン)、食物繊維(水溶性、不溶性)等を含む。なお、本実施形態に係るリンゴエキスは「リンゴ種子エキス」及び「リンゴ果実幹細胞エキス」とは異なるものである。 The apple extract according to the present embodiment contains vitamins (vitamin A, vitamin E, vitamin B1, vitamin B2, niacin, vitamin B6, folic acid, pantothenic acid, vitamin C, carotene) and inorganic substances (potassium, calcium, magnesium, phosphorus, copper). , Manganese), dietary fiber (water-soluble, insoluble), etc. The apple extract according to the present embodiment is different from the "apple seed extract" and the "apple fruit stem cell extract".
リンゴはバラ科リンゴ属の落葉高木樹の果実である。本実施形態に係るリンゴエキスを得るために使用されるリンゴの品種は特に限定されるものではない。 Apple is the fruit of a deciduous tree of the genus Apple of the Rosaceae family. The varieties of apples used to obtain the apple extract according to the present embodiment are not particularly limited.
ここで、一般的なリンゴエキスは、リンゴを抽出溶媒に浸漬して得られる液(或いは当該液を濃縮したもの)である。しかしながら、抽出溶媒にリンゴを浸漬しただけではリンゴが含有する美容成分を十分に抽出することができないか、抽出するまでに長時間を要する。また、抽出時に加温を行う場合、熱の影響により美容成分に変性等が生じる恐れもある。 Here, the general apple extract is a liquid obtained by immersing an apple in an extraction solvent (or a concentrated liquid). However, it is not possible to sufficiently extract the beauty component contained in the apple only by immersing the apple in the extraction solvent, or it takes a long time to extract. In addition, when heating is performed at the time of extraction, the beauty component may be denatured due to the influence of heat.
そのため、本実施形態に係る化粧料組成物においては、リンゴを圧搾して得られたリンゴエキスを用いることが好ましい。リンゴを圧搾することにより、一般的なリンゴエキスに比べ、美容成分の濃度が高いリンゴエキスを簡易に得ることができる。また、リンゴを圧搾する場合には、加温する必要がない。従って、得られるリンゴエキスは、熱の影響による美容成分の変性等が生じ難い。 Therefore, in the cosmetic composition according to the present embodiment, it is preferable to use an apple extract obtained by pressing an apple. By squeezing an apple, an apple extract having a higher concentration of beauty ingredients can be easily obtained as compared with a general apple extract. Also, when squeezing apples, it is not necessary to heat them. Therefore, the obtained apple extract is unlikely to undergo denaturation of beauty ingredients due to the influence of heat.
本実施形態に係るリンゴエキス(リンゴエキスを含む化粧料組成物)は抗シワ効果を有する。抗シワ効果は、人の肌に形成されたシワを軽減する効果、及びシワを形成し難くなる効果の少なくとも一方を意味する。 The apple extract (cosmetic composition containing apple extract) according to the present embodiment has an anti-wrinkle effect. The anti-wrinkle effect means at least one of an effect of reducing wrinkles formed on human skin and an effect of making it difficult to form wrinkles.
本実施形態において、リンゴエキスは、化粧料組成物の総質量に対して、70質量%〜90質量%含まれることが好ましく、90質量%含まれることがより好ましい。このように、リンゴエキスを主とした化粧料組成物を構成することにより、高い抗シワ効果を得ることができる。 In the present embodiment, the apple extract is preferably contained in an amount of 70% by mass to 90% by mass, more preferably 90% by mass, based on the total mass of the cosmetic composition. By constructing the cosmetic composition mainly containing apple extract in this way, a high anti-wrinkle effect can be obtained.
一方、本実施形態に係る化粧料組成物は油分を含まない。 On the other hand, the cosmetic composition according to this embodiment does not contain oil.
油分は、一般的な化粧料組成物に添加されるものであり、たとえば、鉱物油、または植物油等の油脂である。このように、本実施形態に係る化粧料組成物は油分を含まないことから、化粧料組成物を肌に塗布した場合に油分による膜が形成されることがない。従って、高い濃度のリンゴエキスを速やかに、且つ確実に肌の内部まで浸透させることができる。 The oil content is added to a general cosmetic composition, and is, for example, a fat or oil such as a mineral oil or a vegetable oil. As described above, since the cosmetic composition according to the present embodiment does not contain oil, a film due to oil is not formed when the cosmetic composition is applied to the skin. Therefore, the high-concentration apple extract can be quickly and surely penetrated into the skin.
[他の成分]
本実施形態に係る化粧料組成物は、リンゴエキス以外の他の成分(油分を除く)を含有していてもよい。
[Other ingredients]
The cosmetic composition according to the present embodiment may contain ingredients (excluding oil) other than the apple extract.
他の成分としては、人体に使用可能な様々な成分を用いることができる。他の成分は、たとえば、溶媒、防腐剤、緩衝剤、キレート剤、保湿剤、殺菌剤、pH調整剤、香料、酸化防止剤、その他、美容成分に相当する各種剤である。 As other components, various components that can be used in the human body can be used. Other ingredients are, for example, solvents, preservatives, buffers, chelating agents, moisturizers, bactericides, pH regulators, fragrances, antioxidants, and other various agents corresponding to beauty ingredients.
具体的に、本実施形態に係る化粧料組成物は、他の成分として、水素水、アスコルビルリン酸Na、フェノキシエタノール、クエン酸Na、BG(ブチレングリコール)、エタノール、クエン酸、オウゴン根エキス、ナットウガム、クズ根エキス、クロレラエキス、アロエベラ葉エキスを含む。特に、水素水はリンゴエキスの肌内部への浸透性をより高めることができるため、他の成分として好ましい。また、オウゴン根エキスは、保湿湿潤性、抗炎症効果、抗菌効果、及び抗アレルギー効果を有する。ナットウガムは、保湿効果を有する。クズ根エキスは、保湿効果、チロシナーゼ抑制による美白効果、及びシワやタルミの改善効果を有する。クロレラエキスは、保湿効果、及び皮膚細胞を活性化させる効果(シワやシミ、くすみを防止する効果)を有する。アロエベラ葉エキスは、保湿効果、抗炎症効果、及び美白効果を有する。 Specifically, the cosmetic composition according to the present embodiment contains hydrogen water, Na ascorbyl phosphate, phenoxyethanol, Na citrate, BG (butylene glycol), ethanol, citric acid, ginger root extract, and nutto gum as other components. , Kudzu root extract, chlorella extract, aloe vera leaf extract. In particular, hydrogen water is preferable as another component because it can further enhance the permeability of apple extract into the skin. In addition, Scutellaria root extract has moisturizing and moisturizing effects, anti-inflammatory effects, antibacterial effects, and anti-allergic effects. Natto gum has a moisturizing effect. The kudzu root extract has a moisturizing effect, a whitening effect by suppressing tyrosinase, and an effect of improving wrinkles and tarmi. Chlorella extract has a moisturizing effect and an effect of activating skin cells (an effect of preventing wrinkles, stains, and dullness). Aloe vera leaf extract has a moisturizing effect, an anti-inflammatory effect, and a whitening effect.
[化粧料組成物の保存方法]
本実施形態に係る化粧料組成物は、瓶やチューブに充填された後、アルミ製の真空パックで保存される。このようにアルミ製の真空パックで保存することで、化粧料組成物が空気に直接触れることが無い。従って、化粧料組成物の劣化を防止できる。
[Preservation method of cosmetic composition]
The cosmetic composition according to the present embodiment is filled in a bottle or tube and then stored in an aluminum vacuum pack. By storing in a vacuum pack made of aluminum in this way, the cosmetic composition does not come into direct contact with air. Therefore, deterioration of the cosmetic composition can be prevented.
==実施例1==
以下の通り、被験品(化粧料組成物)の抗シワ効果の評価を行った。具体的には、被験品の塗布による肌(目尻周辺)の抗シワ効果を確認するために、単盲検無塗布対照比較試験を実施し、シワグレード判定を行った。シワグレード判定は、日本香粧品学会「化粧品機能評価法ガイドライン」の「新規効能取得のための抗シワ製品評価ガイドライン」(シワグレード判定基準)に基づいて行った。
== Example 1 ==
The anti-wrinkle effect of the test product (cosmetic composition) was evaluated as follows. Specifically, in order to confirm the anti-wrinkle effect of the skin (around the outer corner of the eye) by applying the test product, a single-blind, non-applied controlled comparative test was conducted to determine the wrinkle grade. The wrinkle grade judgment was performed based on the "anti-wrinkle product evaluation guideline for acquiring new efficacy" (wrinkle grade judgment standard) of the "Cosmetic Function Evaluation Method Guideline" of the Japan Cosmetic Science Society.
被験品は、「リンクルノンノン」(ジョジョ株式会社製)である。被験品は、被験品の総質量に対して90質量%のリンゴエキスを含み、残余が水素水、アスコルビルリン酸Na、フェノキシエタノール、クエン酸Na、ブチレングリコール、エタノール、クエン酸、オウゴン根エキス、ナットウガム、クズ根エキス、クロレラエキス、及びアロエベラ葉エキスにより構成される。 The test product is "Wrinkle Nonnon" (manufactured by Jojo Co., Ltd.). The test product contains 90% by mass of apple extract with respect to the total mass of the test product, and the remainder is hydrogen water, Na ascorbyl phosphate, phenoxyethanol, Na citrate, butylene glycol, ethanol, citric acid, ginger root extract, nutto gum. , Kudzu root extract, chlorella extract, and aloe vera leaf extract.
被験者は、(1)目尻周辺に評価測定に影響を与えるような傷、イボ、吹き出物、火傷等がない者、(2)シワグレード(右目尻)が1.0以上3.0以下の者、(3)シワグレード(左目尻)が1.0以上3.0以下の者、(4)左右目尻のシワグレードの差が同程度の者(1.0の差まで許容)を満たす21名(性別:女性、年齢:44.4±4.1歳)を選択した。 The subjects were (1) those who had no scratches, warts, breakouts, burns, etc. that would affect the evaluation measurement around the outer corners of the eyes, and (2) those who had a wrinkle grade (outer corner of the right eye) of 1.0 or more and 3.0 or less. 21 people who meet (3) wrinkle grade (left eye corner) of 1.0 or more and 3.0 or less, and (4) people with similar wrinkle grade difference between left and right eye corners (up to 1.0 difference is allowed) Gender: female, age: 44.4 ± 4.1 years) was selected.
被験者は、1日に2回(朝、晩)、指定された側の目尻周辺に指先で被験品のみを塗布した。更に、被験者は、目尻周辺を含めた半顔全体に2回に分けて被験品を伸ばし塗りした。塗布量は、1回につき3〜4g(500円硬貨大)とした。一方、指定された側の目尻とは反対側には、被験品を含め、何も塗布しなかった。なお、目尻周辺以外の部位については、普段使用しているスキンケア製品の使用を許可した。 Subjects applied only the test product with their fingertips around the outer corners of the eyes on the designated side twice a day (morning and evening). Furthermore, the subject spread and applied the test product to the entire half face including the area around the outer corner of the eye in two steps. The amount of application was 3 to 4 g (500 yen coin size) at one time. On the other hand, nothing was applied to the side opposite to the outer corner of the eye on the designated side, including the test product. For areas other than the outer corners of the eyes, the use of skin care products that are normally used was permitted.
また、
・試験期間中は、被験品以外のスキンケア製品の変更・追加は禁止する。
・試験期間中は、測定部位(左右目尻付近)の剃毛・脱毛・除毛は禁止する。
・試験期間前4週間および試験期間中は、被験部位に影響を与えるようなフェイシャルエステ等のスキンケア施術は受けないこととする。
・試験期間中は、過剰な紫外線の暴露を避けることとする。
・試験期間中は、新たなサプリメント等の摂取は禁止する。
・被験品塗布後の各観察日当日は、当日の検査終了後まで被験品の目尻周辺の使用を禁止する。
という注意事項を設定した。
Also,
・ During the test period, changes or additions to skin care products other than the test products are prohibited.
・ During the test period, shaving, hair removal, and hair removal at the measurement site (near the left and right outer corners of the eyes) are prohibited.
・ During the 4 weeks before the test period and during the test period, skin care treatments such as facial esthetics that affect the test site will not be performed.
-Avoid excessive exposure to UV light during the test period.
・ During the test period, intake of new supplements, etc. is prohibited.
-On the day of each observation after application of the test product, use of the test product around the outer corner of the eye is prohibited until after the end of the examination on that day.
I set a note.
各被験者の左右の目尻について、塗布前、及び塗布4週後(塗布期間28日)にTrained Expertによるシワグレードの判定を行った。 The wrinkle grade of each subject's left and right outer corners of the eyes was determined by Trained Expert before application and 4 weeks after application (application period 28 days).
シワグレード判定の推移(実測値)について、表1及び図1に示す。表1及び図1に示したように、塗布群では、塗布前において2.31±0.73であったのに対し、4週後において1.98±0.98となった。このように、塗布前後でシワグレードの減少(−0.33)がみられた。すなわち、塗布群について、4週後(P=0.001)において有意差が認められた。 The transition of wrinkle grade determination (actual measurement value) is shown in Table 1 and FIG. As shown in Table 1 and FIG. 1, in the coating group, it was 2.31 ± 0.73 before coating, whereas it was 1.98 ± 0.98 after 4 weeks. As described above, a decrease in wrinkle grade (-0.33) was observed before and after application. That is, a significant difference was observed in the application group after 4 weeks (P = 0.001).
一方、非塗布群では、塗布前において2.36±0.73であったのに対し、4週後において2.36±0.74であった。すなわち、塗布前後でシワグレードの変化はほぼ無く、有意差は認められなかった。 On the other hand, in the non-applied group, it was 2.36 ± 0.73 before application, whereas it was 2.36 ± 0.74 after 4 weeks. That is, there was almost no change in wrinkle grade before and after application, and no significant difference was observed.
また、表1に示したように、塗布群と非塗布群の群間比較で、4週後(P=0.017)で有意差が認められた。 In addition, as shown in Table 1, a significant difference was observed after 4 weeks (P = 0.017) in the comparison between the coated group and the non-coated group.
次に、シワグレード判定の推移(相対値)について表2及び図2に示す。表2及び図2に示したように、各観察の値を塗布前の値で除した相対値(%)は、塗布群の場合、4週後において80.4±20.6%であった。一方、非塗布群の場合、4週後において100.0±6.3%であった。塗布群と非塗布群の群間比較で、4週後(P=0.002)で有意差が認められた。 Next, the transition (relative value) of the wrinkle grade determination is shown in Table 2 and FIG. As shown in Table 2 and FIG. 2, the relative value (%) obtained by dividing each observation value by the value before application was 80.4 ± 20.6% after 4 weeks in the case of the application group. .. On the other hand, in the case of the non-applied group, it was 100.0 ± 6.3% after 4 weeks. A significant difference was observed after 4 weeks (P = 0.002) in the comparison between the coated group and the non-coated group.
次に、シワグレード判定の推移(差分値)について表3及び図3に示す。表3及び図3に示したように、各観察の値と塗布前の値の差である差分値は、塗布群の場合、4週後において-0.333±0.329であった。一方、非塗布群の場合、4週後において0.000±0.158であった。塗布群と非塗布群の群間比較で、4週後(P=0.002)で有意差が認められた。 Next, the transition (difference value) of the wrinkle grade determination is shown in Table 3 and FIG. As shown in Table 3 and FIG. 3, the difference value, which is the difference between the value of each observation and the value before application, was -0.333 ± 0.329 after 4 weeks in the case of the application group. On the other hand, in the case of the non-applied group, it was 0.000 ± 0.158 after 4 weeks. A significant difference was observed after 4 weeks (P = 0.002) in the comparison between the coated group and the non-coated group.
このように、シワグレード判定(実測値)では、塗布群において4週後で、塗布前と比べて有意に低値を示した。群間比較では、シワグレードの項目で、4週後に塗布群と非塗布群の間で、非塗布群に対して塗布群が有意に低値であった。シワグレード判定(相対値)では、各観察の値を塗布前の値で除した相対値(%)の群間比較で、シワグレードの項目で、4週後に塗布群と非塗布群の間で、非塗布群に対して塗布群が有意に低値であった。シワグレード判定(差分値)では、各観察の値と塗布前の値の差である差分値の群間比較で、シワグレードの項目で、4週後に塗布群と非塗布群の間で、非塗布群に対して塗布群が有意に低値であった。すなわち、以上の実施例から、シワグレード判定では、シワグレードの項目で、塗布群が非塗布群と比べて4週後に有意に改善が認められた。 As described above, in the wrinkle grade determination (actual measurement value), the value was significantly lower in the application group after 4 weeks than before the application. In the comparison between the groups, the wrinkle grade item was significantly lower in the coated group than in the non-coated group after 4 weeks between the coated group and the non-coated group. In the wrinkle grade judgment (relative value), the relative value (%) obtained by dividing each observation value by the value before application is compared between the groups. , The value in the coated group was significantly lower than that in the non-coated group. In the wrinkle grade judgment (difference value), the difference value, which is the difference between the value of each observation and the value before application, is compared between the groups. The value in the application group was significantly lower than that in the application group. That is, from the above examples, in the wrinkle grade determination, a significant improvement was observed in the wrinkle grade item after 4 weeks in the coated group as compared with the non-coated group.
==実施例2==
以下の通り、被験品(化粧料組成物)の抗シワ効果に関する即効性の評価を行った。
== Example 2 ==
The immediate effect of the test product (cosmetic composition) on the anti-wrinkle effect was evaluated as follows.
被験品は、被験品の総質量に対して、(1)20質量%のリンゴエキスを含むもの、(2)30質量%のリンゴエキスを含むもの、(3)40質量%のリンゴエキスを含むもの、(4)50質量%のリンゴエキスを含むもの、(5)60質量%のリンゴエキスを含むもの、(6)70質量%のリンゴエキスを含むもの、(7)80質量%のリンゴエキスを含むものを用いた。各被験品の残余は、水素水、アスコルビルリン酸Na、フェノキシエタノール、クエン酸Na、ブチレングリコール、エタノール、クエン酸、オウゴン根エキス、ナットウガム、クズ根エキス、クロレラエキス、及びアロエベラ葉エキスにより構成される。 The test product contains (1) 20% by mass of apple extract, (2) 30% by mass of apple extract, and (3) 40% by mass of apple extract with respect to the total mass of the test product. (4) 50% by mass apple extract, (5) 60% by mass apple extract, (6) 70% by mass apple extract, (7) 80% by mass apple extract Was used. The residue of each test product is composed of hydrogen water, Na ascorbyl phosphate, phenoxyethanol, Na citrate, butylene glycol, ethanol, citric acid, ginger root extract, nutto gum, kudzu root extract, chlorella extract, and aloe vera leaf extract. ..
被験者は、年齢の異なる男女4名である。被験者は、指定された対象部位(左右いずれかの腕)に指先で被験品のみを塗布した。被験品の塗布前、及び塗布1時間後に対象部位の撮影を行い、塗布前後でのシワの状態を確認した。 The subjects were four men and women of different ages. The subject applied only the test product to the designated target site (either the left or right arm) with the fingertips. The target site was photographed before the application of the test product and 1 hour after the application, and the state of wrinkles before and after the application was confirmed.
図4A、図5A、図6A、図7A、図8A、図9A、及び図10Aは、被験品塗布前の対象部位を撮影した写真である。図4Bは、図4Aで撮影した対象部位に対して20質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図5Bは、図5Aで撮影した対象部位に対して30質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図6Bは、図6Aで撮影した対象部位に対して40質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図7Bは、図7Aで撮影した対象部位に対して50質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図8Bは、図8Aで撮影した対象部位に対して60質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図9Bは、図9Aで撮影した対象部位に対して70質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。図10Bは、図10Aで撮影した対象部位に対して80質量%のリンゴエキスを含む被験品の塗布を行い、1時間後に撮影した写真である。 4A, 5A, 6A, 7A, 8A, 9A, and 10A are photographs of the target site before application of the test product. FIG. 4B is a photograph taken one hour after the test product containing 20% by mass of apple extract was applied to the target site photographed in FIG. 4A. FIG. 5B is a photograph taken one hour after the test product containing 30% by mass of apple extract was applied to the target site photographed in FIG. 5A. FIG. 6B is a photograph taken one hour after applying a test product containing 40% by mass of apple extract to the target site photographed in FIG. 6A. FIG. 7B is a photograph taken one hour after applying the test product containing 50% by mass of apple extract to the target site photographed in FIG. 7A. FIG. 8B is a photograph taken one hour after the test product containing 60% by mass of apple extract was applied to the target site photographed in FIG. 8A. FIG. 9B is a photograph taken one hour after applying the test product containing 70% by mass of apple extract to the target site photographed in FIG. 9A. FIG. 10B is a photograph taken one hour after the test product containing 80% by mass of apple extract was applied to the target site photographed in FIG. 10A.
図4B、図5B、図6B、図7B、図8B、図9B、及び図10Bの写真から明らかなように、被験品の塗布1時間後にも関わらず、対象部位のシワを低減させることができた。特に70質量%以上のリンゴエキスを含む被験品の場合にはその効果が顕著であった(図9Aと図9B、及び図10Aと図10Bを参照)。 As is clear from the photographs of FIGS. 4B, 5B, 6B, 7B, 8B, 9B, and 10B, wrinkles on the target site can be reduced even after 1 hour of application of the test product. It was. In particular, the effect was remarkable in the case of the test product containing 70% by mass or more of apple extract (see FIGS. 9A and 9B, and FIGS. 10A and 10B).
本発明の実施形態及び実施例を説明したが、これらは例として提示したものであり、発明の範囲を限定することは意図していない。実施形態は、その他の様々な形態で実施されることが可能であり、発明の要旨を逸脱しない範囲で、種々の省略、置き換え、変更を行うことができる。実施形態やその変形は、発明の範囲や要旨に含まれると同様に、特許請求の範囲に記載された発明とその均等の範囲に含まれるものである。 Although embodiments and examples of the present invention have been described, they are presented as examples and are not intended to limit the scope of the invention. The embodiment can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the gist of the invention. The embodiments and variations thereof are included in the scope of the invention described in the claims and the equivalent scope thereof, as are included in the scope and gist of the invention.
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