JP6074866B2 - Alkali-free additive permanent composition using cysteamine base - Google Patents
Alkali-free additive permanent composition using cysteamine base Download PDFInfo
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- 239000000203 mixture Substances 0.000 title claims description 30
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title claims description 25
- 229960003151 mercaptamine Drugs 0.000 title claims description 24
- 239000000654 additive Substances 0.000 title claims 2
- 230000000996 additive effect Effects 0.000 title claims 2
- OGMADIBCHLQMIP-UHFFFAOYSA-N 2-aminoethanethiol;hydron;chloride Chemical compound Cl.NCCS OGMADIBCHLQMIP-UHFFFAOYSA-N 0.000 claims description 5
- 229940097265 cysteamine hydrochloride Drugs 0.000 claims description 5
- 239000004480 active ingredient Substances 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 description 64
- 239000002585 base Substances 0.000 description 19
- 239000003638 chemical reducing agent Substances 0.000 description 17
- CWERGRDVMFNCDR-UHFFFAOYSA-N thioglycolic acid Chemical compound OC(=O)CS CWERGRDVMFNCDR-UHFFFAOYSA-N 0.000 description 17
- 150000003839 salts Chemical class 0.000 description 13
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 description 11
- 238000011282 treatment Methods 0.000 description 11
- 230000003700 hair damage Effects 0.000 description 9
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 7
- 239000003513 alkali Substances 0.000 description 7
- 230000008961 swelling Effects 0.000 description 7
- 230000006378 damage Effects 0.000 description 6
- 239000007800 oxidant agent Substances 0.000 description 6
- 230000001590 oxidative effect Effects 0.000 description 6
- 210000004761 scalp Anatomy 0.000 description 6
- 235000018417 cysteine Nutrition 0.000 description 5
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- PMUNIMVZCACZBB-UHFFFAOYSA-N 2-hydroxyethylazanium;chloride Chemical compound Cl.NCCO PMUNIMVZCACZBB-UHFFFAOYSA-N 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 102000011782 Keratins Human genes 0.000 description 4
- 125000003277 amino group Chemical group 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 108010076876 Keratins Proteins 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- QGZKDVFQNNGYKY-UHFFFAOYSA-N ammonia Natural products N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 238000006386 neutralization reaction Methods 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- NLXLAEXVIDQMFP-UHFFFAOYSA-N Ammonia chloride Chemical compound [NH4+].[Cl-] NLXLAEXVIDQMFP-UHFFFAOYSA-N 0.000 description 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 229960003067 cystine Drugs 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 239000003205 fragrance Substances 0.000 description 2
- 235000011187 glycerol Nutrition 0.000 description 2
- 239000003906 humectant Substances 0.000 description 2
- 230000007794 irritation Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 229920001184 polypeptide Polymers 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 108090000765 processed proteins & peptides Proteins 0.000 description 2
- 239000003223 protective agent Substances 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000003352 sequestering agent Substances 0.000 description 2
- XUXNAKZDHHEHPC-UHFFFAOYSA-M sodium bromate Chemical compound [Na+].[O-]Br(=O)=O XUXNAKZDHHEHPC-UHFFFAOYSA-M 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 description 1
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
- DBVJJBKOTRCVKF-UHFFFAOYSA-N Etidronic acid Chemical compound OP(=O)(O)C(O)(C)P(O)(O)=O DBVJJBKOTRCVKF-UHFFFAOYSA-N 0.000 description 1
- 229920000289 Polyquaternium Polymers 0.000 description 1
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical compound [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 150000001414 amino alcohols Chemical class 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 235000019270 ammonium chloride Nutrition 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- GWBBVOVXJZATQQ-UHFFFAOYSA-L etidronate disodium Chemical compound [Na+].[Na+].OP(=O)([O-])C(O)(C)P(O)([O-])=O GWBBVOVXJZATQQ-UHFFFAOYSA-L 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 239000012458 free base Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000003094 microcapsule Substances 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 235000013772 propylene glycol Nutrition 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- -1 thioglycolic acid ester Chemical class 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/04—Preparations for permanent waving or straightening the hair
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Description
本発明はシステアミンベース｛ｃｙｓｔｅａｍｉｎｅ ｆｒｅｅ ｂａｓｅ｝を含むパーマ剤組成物に関するものであり、より具体的には、システアミンベースを有効性分として含むアルカリ無添加パーマ剤組成物に関するものである。 The present invention relates to a permanent agent composition containing a cysteamine base {systeme free base}, and more specifically to an alkali-free permanent agent composition containing a cysteamine base as an effective component.
毛髪は３つの層で構成されているが、毛髪の一番外側の層から毛表皮、毛皮質、毛髄質となっており、毛髪の主な部分である毛皮質は、主にケラチンという弾力性に富んだ纎維状の硬蛋白質からできている。毛髪のケラチンは、各種アミノ酸の結合で成り立っているポリペプチドによって連結しているとともに、ポリペプチドとポリペプチドの間は、シスチン結合、塩結合、水素結合等の側鎖高分子物質からできており、他のタンパク質に比べ硫黄の含有量が多い。毛髪は、このような構造のケラチンで構成されていることから弾力性があり、曲げてもまた元どおりに戻る性質を持っている。このような毛髪の弾力性を側鎖の切断によって一時的に喪失させた後、新たな位置に再結合させることにより思い通りのウェーブを形成させることがパーマネントウェーブ及びストレート用パーマ剤の原理である。 The hair is composed of three layers. The outermost layer of the hair is the hair epidermis, fur and medulla, and the fur that is the main part of the hair is mainly elastic, called keratin. It is made of fiber-like hard protein. Hair keratin is linked by a polypeptide composed of the bonds of various amino acids, and the polypeptide is composed of side chain macromolecular substances such as cystine bond, salt bond, and hydrogen bond. Higher sulfur content than other proteins. Hair is elastic because it is composed of keratin having such a structure, and has the property of returning to its original state even when bent. The principle of permanent wave and straightening permanent agents is to form such a desired wave by temporarily losing the elasticity of the hair by side chain cleavage and then recombining it with a new position.
毛髪にウェーブ及びストレート等のパーマ効果を付与するパーマネントウェーブ及びストレート用パーマ（ｐｅｒｍ）剤は、一般的に還元性第１剤と酸化性第２剤から構成されるが、具体的にはチオグリコール酸、チオグリコール酸の塩類、チオグリコール酸エステル、システイン、システインの塩類及びシステインのアセチル誘導体等の還元性物質を含む還元性第１剤により毛髪内のシスチン結合を還元させ、ここに過酸化水素水または臭素酸ナトリウムの酸化性物質を含む酸化性第２剤による酸化再結合によりウェーブ及びストレート等を形成させる。また、その効果及び使用性を高めるため、アルカリ剤、浸透剤、安定剤、湿潤剤、養毛剤、着色剤、乳化剤、香料等を使用している。 Permanent wave and straight perm agents that impart perm effects such as wave and straight to hair are generally composed of a reducing first agent and an oxidizing second agent, specifically thioglycol. The cystine bond in the hair is reduced by a reducing first agent containing a reducing substance such as an acid, a salt of thioglycolic acid, a thioglycolic acid ester, cysteine, a salt of cysteine, and an acetyl derivative of cysteine. Waves, straights and the like are formed by oxidative recombination with an oxidizing second agent containing an oxidizing substance of water or sodium bromate. Moreover, in order to improve the effect and usability, an alkali agent, a penetrating agent, a stabilizer, a wetting agent, a hair nourishing agent, a coloring agent, an emulsifier, a fragrance and the like are used.
還元性第１剤は、主剤及び使用法によりチオグリコール酸またはその塩類を主成分とするコールド２浴式パーマネントウェーブ剤、システインを主成分とするコールド２浴式パーマネントウェーブ剤、チオグリコール酸またはその塩類を主成分とする加温２浴式パーマネントウェーブ剤、システインまたはその塩類を主成分とする加温２浴式パーマネントウェーブ剤、チオグリコール酸またはその塩類を主成分とするコールド２浴式縮毛矯正用ストレートクリーム、チオグリコール酸またはその塩類を主成分とするコールド２浴式パーマネントウェーブ剤、チオグリコール酸またはその塩類を主成分とする第１剤の使用時に調剤する発熱２浴式パーマネントウェーブ剤、チオグリコール酸またはその塩類を主成分とする加温２浴式縮毛矯正用ストレートクリーム、チオグリコール酸または塩類を主成分とする高温整髪用熱器具を使用する加温２浴式に区分されており、梯形状に液状、ローション状、クリーム状に分類されている。 The first reducing agent may be a cold two-bath permanent wave agent based on thioglycolic acid or its salts, a cold two-bath permanent wave agent based on cysteine, thioglycolic acid or its Heated two-bath permanent wave agent based on salts, heated two-bath permanent wave agent based on cysteine or its salts, cold two-bath curly hair based on thioglycolic acid or its salts Straightening cream for straightening, cold two-bath permanent wave agent with thioglycolic acid or its salts as the main component, exothermic two-bath type permanent wave agent to be dispensed when using the first component with thioglycolic acid or its salts as its main component , For heating 2 bath type straightening with thioglycolic acid or its salt as main ingredient DOO rate cream, are divided into warm 2 bath type that uses hot hairstyling heat instrument composed mainly of thioglycolic acid or salts, liquid in ladder shape, lotions, are classified creamed.
このような還元性第１剤は、アルカリ剤を必須成分として使用しており、またそのアルカリ剤には、アンモニア水、エタノールアミン、トリエタノールアミン等のアミノアルコール類を使用しているが、このようなアルカリ剤の使用により、還元性第１剤のｐＨは８．９〜１０．０の範囲でアルカリ性領域を構成する。前記のようにアルカリ性を示す還元性第１剤は、アルカリ剤の使用により毛髪を効果的に膨潤させ、膨潤した毛髪内部に還元性第１剤は容易に浸透することができるが、このような毛髪の膨潤は、結局毛髪損傷の原因となる。 Such a reducing first agent uses an alkaline agent as an essential component, and the alkaline agent uses an amino alcohol such as aqueous ammonia, ethanolamine, triethanolamine, etc. By using such an alkaline agent, the pH of the reducing first agent is in the range of 8.9 to 10.0 to constitute an alkaline region. As described above, the reducing first agent exhibiting alkalinity effectively swells the hair by using an alkali agent, and the reducing first agent can easily penetrate into the swollen hair. Hair swelling eventually causes hair damage.
また、酸化性第２剤は酸化剤であり、過酸化水素水及び臭素酸ナトリウムの使用によって膨潤した毛髪を容易に酸化させることができるが、毛髪損傷及び頭皮刺激の原因となり、施術時間についても３０分以上を要する。すなわち、既存のパーマネントェーブ及びストレートナー用還元性及び酸化性製剤は、毛髪のケラチン結合を還元・切断・酸化・再結合させる化学的施術を３０分以上適用することにより毛髪の損傷及び頭皮刺激を惹き起こし、また長期間の毛髪の過度な膨潤により施術後に還元剤及び還元後の還元性物質が膨潤した毛髪に残留して悪臭を残すこととなる。 In addition, the oxidizing second agent is an oxidizing agent, which can easily oxidize swollen hair by using hydrogen peroxide solution and sodium bromate, but it causes hair damage and scalp irritation, and the treatment time It takes 30 minutes or more. In other words, the existing permanent and straightener reducing and oxidizing preparations are applied to chemical treatments that reduce, cleave, oxidize, and recombine keratin bonds in hair for 30 minutes or longer to cause hair damage and scalp irritation. The reductant and the reducing substance after reduction remain on the swollen hair after the treatment due to excessive swelling of the hair for a long period of time and leave a bad odor.
一方、前記の既存の還元性第１剤及び酸化性第２剤の頭皮及び毛髪損傷等の問題点を解決するため、ビタミン等の多くの機能性物質を添加して使用する方法等が提示されているが、これらの機能性成分には、パーマ剤を構成する還元剤、酸化剤及びアルカリ剤等により分解または破壊され、甚だしくは水溶液状でも分解される傾向があり、パーマ剤との混合使用が不可能となる問題点がある。このような問題点を解決し、前記機能性物質の有効性を高めるための研究の一環としてＷ／Ｏ型乳化、リポゾーム、マイクロカプセル方式を選択して製剤化する方法が提示されているが、その有効性は確保されていない。 On the other hand, in order to solve the problems such as scalp and hair damage of the existing reducing first agent and oxidizing second agent, a method of adding many functional substances such as vitamins and the like is presented. However, these functional ingredients tend to be decomposed or destroyed by reducing agents, oxidizing agents, alkaline agents, etc. that make up permanent agents, and even decomposed in an aqueous solution. There is a problem that makes it impossible. As a part of research for solving such problems and enhancing the effectiveness of the functional substance, a method of formulating by selecting W / O type emulsification, liposome, and microcapsule method has been presented. Its effectiveness is not ensured.
現在広く使われているシステアミンパーマ剤は、還元剤にシステアミン塩酸塩を原料として使用していることからパーマ剤製造時に毛髪の膨潤のためにｐＨを９．０〜９．５に調整しなければならない。一般的な還元剤は、たいてい酸性物質であることからパーマ剤製造時に多量のアルカリ剤（例えば、アンモニア、モノエタノールアミン）を使用しなければならない。この時発生する塩（塩化アンモニウム、モノエタノールアミン塩酸塩）はパーマ剤にそのまま存在することとなり、パーマ施術時の毛髪損傷、悪臭等を誘発させる問題点がある。 The currently widely used cysteamine permanent agent uses cysteamine hydrochloride as a raw material as a reducing agent, so the pH must be adjusted to 9.0 to 9.5 for hair swelling during the manufacture of the permanent agent. Don't be. Since a general reducing agent is usually an acidic substance, a large amount of an alkaline agent (for example, ammonia, monoethanolamine) must be used when producing a permanent agent. The salt (ammonium chloride, monoethanolamine hydrochloride) generated at this time is present in the permanent agent as it is, and there is a problem inducing hair damage, bad odor, etc. during the permanent treatment.
本発明者はこのような問題点を解決することのできるパーマ剤を開発すべく研究を重ねた結果、塩酸塩を除去した純粋なシステアミンベースを使用することで、アルカリを全く添加せずにそれ自体のｐＨ（９．５）を利用することのできる純粋なパーマ剤を開発し、本発明を完成させた。 The inventor has conducted research to develop a permanent agent that can solve such problems, and as a result, by using a pure cysteamine base from which hydrochloride has been removed, it can be obtained without adding any alkali. A pure permanent agent that can utilize its own pH (9.5) was developed to complete the present invention.
したがって、本発明で解決しようとする技術的課題は、パーマ施術時の毛髪損傷及び悪臭を制御することのできるパーマ剤を提供するためのものである。 Therefore, the technical problem to be solved by the present invention is to provide a permanent agent capable of controlling hair damage and malodor during perm treatment.
前記の技術的課題を解決するため、本発明は、システアミンベースを有効成分として含むパーマ剤組成物を提供する。 In order to solve the above technical problem, the present invention provides a permanent composition containing cysteamine base as an active ingredient.
上述したように、本発明によるパーマ剤組成物は、システアミンベース自体、アミノ基によりｐＨが９．５程度であることから、アルカリ剤を別途添加せずとも充分な毛髪膨潤を誘導することができ、ウェーブまたはストレートの形成力においても既存のパーマ剤と比べて全く劣らない。また、既存のパーマ剤の場合、残存塩酸とアルカリ剤の中和により発生するモノエタノールアミン塩酸塩がパーマ剤に残留して毛髪を損傷させるのとは異なり、本発明のパーマ剤は、毛髪及び頭皮損傷を著しく緩和させるだけでなく、施術時または施術後に発生する悪臭を著しく減らすことができる。 As described above, the permanent composition according to the present invention has a pH of about 9.5 due to the cysteamine base itself and amino groups, and therefore can induce sufficient hair swelling without the addition of an alkaline agent. Also, the wave or straight forming ability is not inferior to that of existing permanent agents. Further, in the case of an existing permanent agent, monoethanolamine hydrochloride generated by neutralization of residual hydrochloric acid and an alkaline agent remains in the permanent agent and damages the hair. Not only can the scalp damage be remarkably relieved, but the malodor that occurs during or after treatment can be significantly reduced.
本発明のパーマ剤組成物は、システアミンベースを有効成分として含むことを特徴とする。 The permanent composition of the present invention is characterized by containing cysteamine base as an active ingredient.
本発明のパーマ剤組成物に使用されるシステアミンベースは、分子量が７７．１５である、アルカリを添加しないパーマ還元剤である。 The cysteamine base used in the permanent agent composition of the present invention is a permanent reducing agent having a molecular weight of 77.15 and no addition of alkali.
本発明のパーマ剤組成物は、システアミンベースを組成物の総重量を基準として０．１乃至１００重量パーセントの量で含むことができる。 The permanent composition of the present invention may comprise a cysteamine base in an amount of 0.1 to 100 weight percent, based on the total weight of the composition.
本発明のパーマ剤組成物は、ｐＨ９．３乃至９．７、好ましくはｐＨ９．５である。 The permanent composition of the present invention has a pH of 9.3 to 9.7, preferably pH 9.5.
本発明で使用するシステアミンベースは、それ自体、アミノ基によりｐＨが９．５程度であることから、アルカリ剤を添加せずとも充分な毛髪膨潤を誘導することができる。 The cysteamine base used in the present invention itself has a pH of about 9.5 due to an amino group, so that sufficient hair swelling can be induced without adding an alkaline agent.
本発明のパーマ剤組成物は、通常パーマ剤に添加される増粘剤、香料、界面活性剤、毛髪保護剤、安定剤、保湿剤、金属封鎖剤、着色剤、乳化剤、精製水等を含有することがあるが、前記界面活性剤にはポリソルベート、ラウリル硫酸ナトリウム、セテアレス、ステアレス等を選択して使用することができ、全体の組成物重量に対して０．１〜５重量パーセント使用するのが好ましい。 The permanent composition of the present invention contains a thickener, a fragrance, a surfactant, a hair protecting agent, a stabilizer, a humectant, a metal sequestering agent, a coloring agent, an emulsifier, purified water, etc., which are usually added to the permanent agent. The surfactant may be selected from polysorbate, sodium lauryl sulfate, cetealess, steareth, etc., and used in an amount of 0.1 to 5 percent by weight based on the total composition weight. Is preferred.
前記毛髪保護剤には、第四級アンモニウム塩類、ポリクウォータニウム類等を選択して使用することができ、全体の組成物重量に対して０．０５〜１重量パーセント使用することが好ましい。 As the hair protecting agent, quaternary ammonium salts, polyquaterniums and the like can be selected and used, and it is preferable to use 0.05 to 1 weight percent with respect to the total weight of the composition.
前記安定剤には、カボモ類、セルロース類、クエン酸及びその塩類、リン酸及びその塩類等を選択して使用することができ、全体の組成物重量に対して０．１〜３重量パーセント使用することが好ましい。 As the stabilizer, cabamos, celluloses, citric acid and salts thereof, phosphoric acid and salts thereof can be selected and used, and used in an amount of 0.1 to 3 weight percent with respect to the total composition weight. It is preferable to do.
前記保湿剤には、グリセリン、プロピレングリコール、ヨウ素、グリセリン、ブチレングリコール等を選択して使用することができ、全体の組成物重量に対して３〜１５重量パーセント使用することが好ましい。 As the humectant, glycerin, propylene glycol, iodine, glycerin, butylene glycol and the like can be selected and used, and it is preferable to use 3 to 15 weight percent with respect to the total composition weight.
前記金属封鎖剤には、エチドロニック酸、エチドロン酸ナトリウム、ジソジウムＥＤＴＡ、テトラソジウムＥＤＴＡ等を選択して使用することができ、全体の組成物重量に対して０．１〜３重量パーセント使用することが好ましい。 For the metal sequestering agent, etidronic acid, sodium etidronate, disodium EDTA, tetrasodium EDTA, etc. can be selected and used, and it is preferably used in an amount of 0.1 to 3 weight percent based on the total composition weight. .
その他、必要に応じ、本発明の目的を阻害しない水準でパーマ剤組成物に使用可能な成分を当業者の選択により適切に選択使用することができる。 In addition, if necessary, components that can be used in the permanent composition at a level that does not impair the object of the present invention can be appropriately selected and used according to selection by those skilled in the art.
本発明のパーマ剤組成物は、パーマネントウェーブ及びストレートナー用の組成物とすることができる。 The permanent agent composition of the present invention may be a permanent wave and straightener composition.
上述したように、本発明によるパーマ剤組成物は、システアミンベース自体、アミノ基によりｐＨが９．５程度であることから、アルカリ剤を別途添加せずとも充分な毛髪膨潤を誘導することができ、ウェーブまたはストレートの形成力においても既存のパーマ剤と比べて全く劣らない。また、既存のパーマ剤の場合、残存塩酸とアルカリ剤の中和により発生するモノエタノールアミン塩酸塩がパーマ剤に残留して毛髪を損傷させるのとは異なり、本発明のパーマ剤は、毛髪及び頭皮損傷を著しく緩和させるだけでなく、施術時または施術後に発生する悪臭を著しく減らすことができる。 As described above, the permanent composition according to the present invention has a pH of about 9.5 due to the cysteamine base itself and amino groups, and therefore can induce sufficient hair swelling without the addition of an alkaline agent. Also, the wave or straight forming ability is not inferior to that of existing permanent agents. Further, in the case of an existing permanent agent, monoethanolamine hydrochloride generated by neutralization of residual hydrochloric acid and an alkaline agent remains in the permanent agent and damages the hair. Not only can the scalp damage be remarkably relieved, but the malodor that occurs during or after treatment can be significantly reduced.
以下に、本発明の理解を助けるために実施例等を挙げて詳細に説明する。但し、本発明による実施例は、様々な異なる形態に変形されることができ、本発明の範囲は下記の実施例に限定されるものと解釈されてはならない。本発明の実施例は、当業界において平均的な知識を持つ者に対し、本発明をより完全に説明するために提供されるものである。 Hereinafter, examples and the like will be described in detail in order to help understanding of the present invention. However, the examples according to the present invention can be modified in various different forms, and the scope of the present invention should not be construed to be limited to the following examples. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the invention to those skilled in the art.
パーマ還元剤の同一当量における消費アルカリ測定
下記表１に示すとおり、各パーマ還元剤の同一当量における消費アルカリを測定した。その結果は、下記表２に示した。
Measurement of consumption alkali at the same equivalent of the permanent reducing agent As shown in Table 1 below, the consumption alkali at the same equivalent of each permanent reducing agent was measured. The results are shown in Table 2 below.
条件：１）還元剤濃度／０．５当量
２）ｐＨ／９．５
３）アルカリ剤／モノエタノールアミン
４）用量／１００ｇ パーマ剤
Conditions: 1) Reducing agent concentration / 0.5 equivalent 2) pH / 9.5
3) Alkaline agent / monoethanolamine 4) Dose / 100g Perm
前記表２から、本発明で使用するシステアミンベースは、アルカリを全く消費しないことがわかる。 From Table 2, it can be seen that the cysteamine base used in the present invention does not consume any alkali.
パーマ還元剤の同一当量パーマのウェーブ効果測定
前記表１に示したそれぞれのパーマ還元剤の同一当量パーマのウェーブ効果を下記の条件で測定し、その結果を表3に示した。▲ 弱い、△ 普通、◎ 良好、○ 大変良好で表記した。
Wave effect measurement of the same equivalent perm of the permanent reducing agent The wave effect of the same equivalent permanent of each of the permanent reducing agents shown in Table 1 was measured under the following conditions, and the results are shown in Table 3. ▲ Weak, △ Normal, ◎ Good, ○ Very good.
条件 : １） 毛髪／健康毛
２）還元剤濃度／０．５当量
３）ｐＨ／９．５
４）アルカリ剤／モノエタノールアミン
５）放置時間３０分、未加熱
６）酸化剤／過酸化水素水
Conditions: 1) Hair / Healthy hair 2) Reducing agent concentration / 0.5 equivalent 3) pH / 9.5
4) Alkaline agent / monoethanolamine 5) Standing time 30 minutes, unheated 6) Oxidizing agent / hydrogen peroxide solution
前記表３から、本発明のシステアミンベースは、ウェーブ効果が非常に優秀であることがわかる。 From Table 3, it can be seen that the cysteamine base of the present invention has a very excellent wave effect.
システアミンベースパーマ剤の毛髪損傷度測定
下記の条件で本発明のシステアミンベース（ＨＳ−ＣＨ２−ＣＨ２−ＮＨ２）パーマ剤の毛髪損傷度を測定し、その結果を下記表４に示した。比較のため、システアミン塩酸塩（ＨＳ−ＣＨ２−ＣＨ２−ＮＨ２．ＨＣＬ）を使用した。
Measurement of hair damage degree of cysteamine base permanent agent The hair damage degree of the cysteamine base (HS-CH2-CH2-NH2) permanent agent of the present invention was measured under the following conditions, and the results are shown in Table 4 below. For comparison, cysteamine hydrochloride (HS-CH2-CH2-NH2.HCL) was used.
条件：１）毛髪／健康毛
２）還元剤濃度／０．５当量
３）ｐＨ／９．５
４）アルカリ剤／モノエタノールアミン
５）放置時間３０分、未加熱
６）酸化剤／過酸化水素水
Conditions: 1) Hair / Healthy hair 2) Reducing agent concentration / 0.5 equivalent 3) pH / 9.5
4) Alkaline agent / monoethanolamine 5) Standing time 30 minutes, unheated 6) Oxidizing agent / hydrogen peroxide solution
前記表４から、本発明のシステアミンベースでは、毛髪損傷が既存のパーマ還元剤であるシステアミン塩酸塩に比べて非常に良好であることがわかる。 From Table 4, it can be seen that the cysteamine base of the present invention has very good hair damage compared to cysteamine hydrochloride, which is an existing permanent reducing agent.
システアミンベースパーマ剤施術後の臭い測定
下記の条件で本発明のシステアミンベース（ＨＳ−ＣＨ２−ＣＨ２−ＮＨ２）パーマ剤施術後の臭いを測定し、その結果を下記表５に示した。比較のためにシステアミン塩酸塩（ＨＳ−ＣＨ２−ＣＨ２−ＮＨ２．ＨＣＬ）を使用した。
Odor measurement after cysteamine base permanent treatment The odor after cysteamine base (HS-CH2-CH2-NH2) permanent treatment of the present invention was measured under the following conditions, and the results are shown in Table 5 below. For comparison, cysteamine hydrochloride (HS-CH2-CH2-NH2.HCL) was used.
条件：１）毛髪／健康毛
２）還元剤濃度／０．５当量
３）ｐＨ／９．５
４）アルカリ剤／モノエタノールアミン
５）放置時間３０分、未加熱
６）酸化剤／過酸化水素水
Conditions: 1) Hair / Healthy hair 2) Reducing agent concentration / 0.5 equivalent 3) pH / 9.5
4) Alkaline agent / monoethanolamine 5) Standing time 30 minutes, unheated 6) Oxidizing agent / hydrogen peroxide solution
前記表５から、本発明のシステアミンベースでは、施術後の臭いが格段に減少していることがわかる。 From Table 5, it can be seen that in the cysteamine base of the present invention, the odor after the treatment is remarkably reduced.
上述したように、本発明によるパーマ剤組成物は、システアミンベース自体、アミノ基によりｐＨが９．５程度であることから、アルカリ剤を別途添加せずとも充分な毛髪膨潤を誘導することができ、ウェーブまたはストレートの形成力においても既存のパーマ剤と比べて全く劣らない。また、既存のパーマ剤の場合、残存塩酸とアルカリ剤の中和により発生するモノエタノールアミン塩酸塩がパーマ剤に残留して毛髪を損傷させるのとは異なり、本発明のパーマ剤は、毛髪及び頭皮損傷を著しく緩和させるだけでなく、施術時または施術後に発生する悪臭を著しく減らすことができる。したがって、本発明のシステアミンベースパーマ剤組成物は、当分野において非常に有用に使用することができるものと期待される。 As described above, the permanent composition according to the present invention has a pH of about 9.5 due to the cysteamine base itself and amino groups, and therefore can induce sufficient hair swelling without the addition of an alkaline agent. Also, the wave or straight forming ability is not inferior to that of existing permanent agents. Further, in the case of an existing permanent agent, monoethanolamine hydrochloride generated by neutralization of residual hydrochloric acid and an alkaline agent remains in the permanent agent and damages the hair. Not only can the scalp damage be remarkably relieved, but the malodor that occurs during or after treatment can be significantly reduced. Therefore, it is expected that the cysteamine-based permanent agent composition of the present invention can be used very usefully in the art.
Claims (4)
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| KR1020140167141A KR20160063642A (en) | 2014-11-27 | 2014-11-27 | A perm composition comprising cysteamine free base |
| KR10-2014-0167141 | 2014-11-27 |
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