JP2011201834A - Gel-like composition for external use - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a gel-like composition for external use containing a large amount of alcohol with suppressed stickiness.SOLUTION: The gel-like composition for external use includes following ingredients (1) to (5): (1) 20-50 mass% of ethanol based on the composition; (2) 0.1-1 mass% of a hydrophobically modified alkyl cellulose based on the composition; (3) 0.1-0.5 mass% of a carboxyvinyl polymer or a salt thereof based on the composition; (4) a water-insoluble ingredient; and (5) water.

Description

  The present invention relates to a gel composition that can be used as a composition for external use such as cosmetics. The gel composition of the present invention is suitable for use as a body cosmetic.

  A gel-like composition for external use is a dosage form called jelly or gel, has a uniform appearance, and is usually transparent or translucent, and generally gives a fresh feel when used. In the past, it has been used as a makeup base for summer, taking advantage of the fresh and refreshing feel that is characteristic of aqueous gels. Recently, various formulation technologies have been developed, and various aqueous and oily gels have been provided, and functions other than hydration and moisturization, that is, functions such as blood circulation promotion, washing and makeup removal have been added.

  Since the aqueous gel contains a large amount of water, it is used as a base base for hydration to the skin, a moisturizing effect and a refreshing effect, and a base base for a light make-up cleansing agent. The feeling of use is refreshing, refreshing and refreshing, so it is used as a product for summer and oily skin.

  Since oily gel contains a lot of oil, it is used for winter and dry skin in order to maintain a moisturizing effect when used in combination with water replenishment, skin lotion and the like. In addition, since it is familiar with hard make, it can be used as a make-up remover by appropriately selecting the type and amount of active agent to make it washable.

JP 2002-322045 A JP 2004-75604 A Japanese Patent Laid-Open No. 3-151330

  In addition to the above dosage forms, a gel-external composition includes a type in which a large amount of alcohol is blended (high alcohol blending type). This form of gel is accompanied by a refreshing sensation and is found primarily in hair styling. Considering application to the body, the amount of the carboxyvinyl polymer as a thickener is large, and the film feeling and stickiness are too strong, which is inappropriate.

  In particular, in body cosmetics, a strong scent is often preferred, so the blending amount of the fragrance tends to increase, and a refreshing agent such as menthol is often blended. Therefore, the ethanol concentration in the preparation tends to be increased to ensure the dissolved or dispersed state of these components. When the ethanol concentration is high, ethanol is first diffused during use, and the thickener remaining on the skin often causes stickiness.

  An object of the present invention is to provide a gel-like external composition containing a high alcohol content and having reduced stickiness.

  As a result of studies aimed at solving the above problems, the present inventor has found that this can be solved by providing the following gel external composition.

That is, this invention is invention which provides the gel-form external composition (henceforth the composition of this invention) characterized by containing the component of following (1)-(5).
(1) ethanol is 20 to 50% by mass of the composition,
(2) 0.1-1% by mass of the hydrophobic modified alkyl cellulose,
(3) 0.1 to 0.5% by mass of the carboxyvinyl polymer or a salt thereof,
(4) a water-insoluble component,
(5) Water.

  Here, the “water-insoluble component” means all components that are sparingly soluble in water, such as fragrance components, fats and oils, refreshing agents, oil-soluble drugs, and peptides. As described above, in body applications, a fragrance component, a refreshing agent, and an oil-soluble drug are often blended as a water-insoluble component.

  It is preferable that a nonionic surfactant is further blended in the composition of the present invention from the viewpoint of stable blending of water-insoluble components. In addition, when the nonionic surfactant is a nonionic surfactant having an HLB value of 7 or more, the water-insoluble component can be easily solubilized in the system. Polyoxyethylene may be abbreviated as “POE”, and polyoxypropylene may be abbreviated as “POP”.

  The composition of the present invention is an effective feature that even when a relatively large amount of oil is blended in a system in which ethanol is actively blended, stickiness due to a thickener, etc. accompanying the drying is sufficiently suppressed. A gel-like composition for external use. This feature of the composition of the present invention is suitable for use as a body cosmetic.

[Essential ingredients]
(1) Water-insoluble component The water-insoluble component is not particularly limited, and as described above, one kind or two or more kinds selected from a fragrance ingredient, an oil and fat, a refreshing agent, an oil-soluble drug, a peptide, and the like. Different components are mentioned. Examples of the fragrance component include linalool, linalyl acetate, limonene, citrol, methylionone benzyl acetate, methyl dehydrojasmonate, phenylethyl alcohol, musk ketone, sandalol, α-hexylcinnamic aldehyde, TEC, citronellol and the like. Can be mentioned. Examples of the refreshing agent include menthol derivatives such as menthol and lactate menthyl, camphor and camphor derivatives. In addition, essential oils such as eucalyptus oil and mint (thin cargo) oil containing these refreshing agents are also preferably used as water-insoluble components. Other essential oils include bergamot oil, clove oil, geranium oil, lavender oil, lemon oil, lemongrass oil, rosemary oil, tea tree oil, and ylang ylang oil. Oil-soluble herbal medicines can also be used. In addition, oil-soluble ultraviolet absorbers, oil-soluble drugs, oil-soluble vitamins, peptides and the like can be mentioned. The range of the amount of the water-insoluble component in the composition of the present invention varies depending on the type of the component and is not strictly defined. For example, the above-described fragrance components and refreshing agents (essential oils) Is preferably about 0.01 to 1.5% by mass, more preferably 0.3 to 1% by mass, and most preferably 0.4 to 0.8% by mass. Other water-insoluble components can be blended accordingly.

(2) Hydrophobically modified alkylcellulose The hydrophobically modified alkylcellulose blended in the present composition is a hydrophobically modified alkylcellulose represented by the general formula (I).

[Wherein, R is a bonding group R ¹ -R ² , and R ¹ may be the same or different, and — [CH ₂ CH (CH ₃ ) O] _r —, — [CH ₂ CH ₂ O] _r -, _{and, - [CH 2 CH (OH} ) CH 2 O] r - ( wherein, r is an integer of 0 to 4) one or more groups selected from a, ^{R 2} is carbon It is at least one group selected from a hydrocarbon group having 12 to 28 atoms, a hydrogen atom, and an alkyl group having 1 to 4 carbon atoms, and at least one R ² has 12 carbon atoms. -28 hydrocarbon groups. A is a group — (CH ₂ ) _t — (t is an integer of 1 to 3), and s is a number of 100 to 10,000. ]

  The hydrophobically modified alkyl cellulose (I) is a water-soluble cellulose ether derivative having a long-chain alkyl group that is a hydrophobic group introduced therein, and the composition of the present invention may contain one or more of these components. it can.

The method for producing hydrophobically modified alkyl cellulose (I) is generally based on a water-soluble cellulose ether derivative as a group, specifically methyl cellulose (R, ie, R in R ¹ -R ² is 0 in R ^1. R ¹ is not present, R ² is a hydrogen atom or a methyl group), ethyl cellulose (as described above, R ¹ is not present, R ² is a hydrogen atom or an ethyl group), propyl cellulose (as described above) R ¹ does not exist, R ² is a hydrogen atom or a propyl group), butyl cellulose (the same as above, R ¹ does not exist, R ² is a hydrogen atom or a butyl group), hydroxyethyl cellulose (bonding group R ¹ -R ² , R ¹ is a group — [CH ₂ CH ₂ O] _r — (r = 0 or 1, r in at least one R ¹ in the compound is 1 or more), and R ² is Hydrogen atom ), (Among the linking groups ^{R 1} -R ^{2, R} 1 is a group _{- [CH 2 CH (CH 3} ) O] hydroxypropylcellulose r - (r = 0 to 5, preferably an integer of 0 to 3, And at least one R ¹ in the compound is 1 or more, and R ² is a hydrogen atom), hydroxypropylmethylcellulose (of the bonding groups R ¹ -R ² , R ¹ is a group — [CH ₂ CH (CH ₃ ) O] _r — (r = 0 to 5, preferably an integer of 0 to 3, r in at least one R ¹ in the compound is 1 or more), and R ² is a hydrogen atom or methyl A long-chain alkyl group-introducing compound, specifically, the following long-chain alkyl glycidyl ether (I ′):

  [R 'is an alkyl group having 10 to 28 carbon atoms, preferably 12 to 22 carbon atoms. ] Can be contacted in the presence of an alkali catalyst to obtain the desired hydrophobically modified alkyl cellulose (I).

The content of the group —CH ₂ CH (OH) CH ₂ OR ′ introduced as a part of R by this reaction in the hydrophobically modified alkylcellulose (I) is based on the hydrophobically modified alkylcellulose (I). It is about 0.1-5.0 mass%. In order to obtain such a content, the molar ratio, reaction time, type of alkali catalyst, etc. in the reaction of the water-soluble cellulose ester derivative and the long-chain alkyl glycidyl ether are appropriately selected, and the hydrophobic modified alkyl cellulose Manufacturing can be performed. After the reaction, a hydrophobically modified alkyl cellulose (I) suitable for blending into the composition of the present invention can be produced by carrying out purification steps such as neutralization, filtration, washing, drying and sieving of the reaction product. it can. The method for introducing a long chain alkyl group is not limited to the above.

Of the above water-soluble cellulose ether derivatives, hydroxypropylmethylcellulose or hydroxyethylcellulose is preferable, and hydroxypropylmethylcellulose is particularly preferable (in this way, R of hydrophobic alkylcellulose (I) is hydrogen An atom, a methyl group, a bonding group R ¹ -R ² that is “R ¹ : — [CH ₂ CH (CH ₃ ) O] _r —, R ² : a hydrogen atom”, and “R ¹ : —CH ₂ CH ( OH) CH ₂ O—, R ² : R ′ ”, the four groups of the linking group R ¹ -R ² , t of group A is 1, and A is a methylene group). Further, R ′ of the long-chain alkyl glycidyl ether (I ′) is preferably a stearyl group (—C ₁₈ H ₃₇ ) or a cetyl group (—C ₁₆ H ₃₃ ) (therefore, the group —CH ₂ CH (OH) CH ₂ OR ′ becomes the group —CH ₂ CH (OH) CH ₂ O—C ₁₈ H ₃₇ or —CH ₂ CH (OH) CH ₂ O—C ₁₆ H ₃₃ ).

  Hydrophobic hydroxypropylmethylcellulose having a hydrophobic group R ′ as a stearyl group, which is the most preferred embodiment of the hydrophobically modified alkylcellulose (I), is commercially available from Daido Kasei Kogyo Co., Ltd. under the trade name of Sangelose. It is also possible to use a commercially available product as a component of the composition of the present invention. (Sangelose 90L, 90M, 90H, 60L, 60M, 60H)

  The blending amount of the hydrophobically modified alkyl cellulose (I) in the composition of the present invention is preferably 0.1 to 1% by mass, more preferably 0.3 to 0.8% by mass, and 0.4 to 0.00%. 6% by mass is most preferred. If the blending amount is less than 0.1% by weight of the composition, an improvement in effect commensurate with the blending amount cannot be expected, and if the blending amount exceeds 1% by weight, it is difficult to exert a desired stickiness suppressing effect. It becomes.

(3) Carboxyvinyl polymer or salt thereof The carboxyvinyl polymer blended in the composition of the present invention is a polyacrylic acid cross-linked polymer, and is known by a Japanese cosmetic display name (hereinafter also referred to as display name) called carbomer. Yes. Specifically, it is a polymer of acrylic acid crosslinked with pentaerythryl allyl ether, sucrose allyl ether or propylene allyl ether, and is provided as an emulsion stabilizer or a hydrophilic thickener. The composition of the present invention includes the carboxyvinyl polymer itself, its calcium salt (partially potassium salt) (carbomer (Ca / K)), potassium salt (carbomer K), sodium salt (carbomer Na), triethanolamine salt. A salt of a carboxyvinyl polymer such as (carbomer TEA) can be used. Examples of commercially available products include Syntalen K (manufactured by Wako Pure Chemical Industries, Ltd.), Carbopol 934, 934P, 940, 941, 974, 980, 981, 2980, 5984, EDT 2050 (Nikko Chemicals).

  The blending amount of the carboxyvinyl polymer or a salt thereof in the composition of the present invention is preferably 0.1 to 0.5% by mass, more preferably 0.1 to 0.4% by mass, and 0.1 to 0%. .3% by mass is most preferred. When the blending amount exceeds 0.5% by mass of the composition, a tendency to have a film feeling and stickiness is recognized, and when it is less than 0.1% by mass, it is difficult to achieve a viscosity suitable as a gel composition. It becomes.

(4) Ethanol and water As described above, ethanol is preferably in the range of 20 to 50% by mass of the composition, more preferably 25 to 45% by mass, and most preferably 30 to 40% by mass. Appropriate amounts can be freely selected according to the characteristics of the product. The water may be tap water, purified water, or ion exchange water, and can be blended as the remaining amount of all other blending components.

[Selective ingredients]
(5) Nonionic surfactant It is one of the suitable aspects to mix | blend a nonionic surfactant with the composition of this invention. The kind of nonionic surfactant that can be blended is not particularly limited. For example, POE-sorbitan fatty acid esters (for example, POE-sorbitan monooleate, POE-sorbitan monostearate, POE-sorbitan monooleate, POE- Sorbitan tetraoleate, etc.); POE sorbite fatty acid esters (for example, POE-sorbite monolaurate, POE-sorbite monooleate, POE-sorbite pentaoleate, POE-sorbite monostearate, etc.); POE-glycerin fatty acid ester (For example, POE-glycerol monostearate, POE-glycerol monoisostearate, POE-monooleate such as POE-glycerol triisostearate, etc.); POE-fatty acid esters (eg, POE-distearate, POE-monodiolate, Ethylene glycol distearate, etc.); POE-alkyl A (Eg POE-lauryl ether, POE-oleyl ether, POE-stearyl ether, POE-behenyl ether, POE-2-octyldodecyl ether, POE-cholestanol ether, etc.); Pluronic type (eg, pluronic etc.) POE / POP-alkyl ethers (for example, POE / POP-cetyl ether, POE / POP-decyltetradecyl ether, POE / POP-monobutyl ether, POE / POP-hydrogenated lanolin, POE / POP-glycerin ether) Tetra-POE / tetra-POP-ethylenediamine condensates (eg, Tetronic); POE-castor oil hydrogenated castor oil derivatives (eg, POE-castor oil, POE-hardened castor oil, POE-hardened castor oil monoisostearate POE-hardened castor oil triisostearate, POE-hardened castor oil monopyroglutamic acid monoisostearic acid diester, POE-hardened castor Maleic acid, etc.); POE-beeswax lanolin derivatives (eg POE-sorbite beeswax etc.); alkanolamides (eg coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide etc.); POE-propylene glycol fatty acid ester POE-alkylamines; POE-fatty acid amides; sucrose fatty acid esters; alkyl ethoxydimethylamine oxides; trioleyl phosphoric acid and the like.

  It is a preferred embodiment to make the composition of the present invention solubilized. Therefore, it is possible to mix a nonionic surfactant as a solubilizer. Specifically, the nonionic surfactant is preferably a nonionic surfactant having an HLB value of 7 or more, particularly a nonionic surfactant having an HLB value of 8 to 14. Particularly suitable nonionic surfactants that can be blended in the composition of the present invention include POE • POP-alkyl ethers, among which PPG-20decyltetradeceth-10 (display name: generic name is POE) (10) .POP (20) 2-decyltetradecyl ether).

  The amount of the nonionic surfactant to be blended with the composition of the present invention can be freely selected according to the type of nonionic surfactant to be blended, the specific purpose of the blending, the form of the composition, etc. It can be selected and is not particularly limited. For example, when the nonionic surfactant is a nonionic surfactant having an HLB value of 7 or more and takes the form of a gel composition in which the composition is solubilized, the nonionic surfactant is used. Is preferably blended in the range of 0.05 to 0.5% by mass of the composition, and 0.1 to 0.3% by mass is particularly suitable. If the blending amount is less than 0.05% by weight of the composition, it is difficult to sufficiently solubilize the water-insoluble component. If the blending amount exceeds 0.5% by weight, the feeling of use tends to be impaired. Thus, an effect commensurate with the increase in the blending amount is not recognized.

(6) Other compounding components In the composition of the present invention, general components blended in a composition for external use such as cosmetics within the qualitative / quantitative range that does not substantially impede the effects of the present invention, particularly A water-soluble component can be blended as necessary. For example, surfactants other than nonionic surfactants, hydrophilic UV absorbers, hydrophilic drugs, polyhydric alcohols such as glycerin, 1,3-butylene glycol, dipropylene glycol (polyhydric alcohols are hydrophobically modified alkyls) Examples thereof include thickeners other than carboxyvinyl polymers such as xanthan gum, antioxidants, pH adjusters, sequestering agents, and the like.

[Form of composition]
The composition of this invention can be manufactured according to the manufacturing process of a normal external composition. That is, it can be produced by simply mixing the blended components at room temperature. However, it is preferable that the hydrophobic modified alkylcellulose is pre-swelled and dispersed in hot water and then mixed with other components in a state cooled to room temperature. In addition, when the composition of the present invention is a solubilized type, a solubilized phase prepared in advance (usually prepared by separately preparing an aqueous phase and an alcohol phase and gradually adding the aqueous phase to the alcohol phase). And a wet-modified hydrophobic modified alkyl cellulose can also be produced. Even if the composition of the present invention is in an emulsified form, it can also be produced by mixing a preliminarily prepared emulsified phase and a swollen hydrophobic modified alkylcellulose. Preparation of a solubilization phase and an emulsification phase can be performed according to the manufacturing method of a normal solubilization composition and an emulsification composition.

  In addition, the composition of the present invention is a gel-like external composition and can be applied to any cosmetics, pharmaceuticals, and quasi drugs for external use (including scalp and hair). The dosage form is basically a gel form. The use is not particularly limited for hair, face, body, etc., but for the purpose of the present invention, relative to the relative amount of ethyl alcohol blended, the body use that allows a refreshing feel to be used Can be cited as one of the preferred uses.

  EXAMPLES The present invention will be specifically described below with reference to examples, but this is not intended to limit the scope of the present invention. Moreover, a compounding quantity is the mass% with respect to a compounding object unless there is particular notice.

[Test method]
Below, the test method performed in order to verify the effect of this invention is disclosed.

(1) Viscosity measurement The viscosity was measured using a VS-A1 type (Shibaura System Co., Ltd.) of a single cylindrical rotational viscometer (Bismetron viscometer). The measurement temperature is 30 ° C. Evaluation is based on the following criteria.
<Evaluation criteria>
○: 15,000 mPa · s or more ×: less than 15,000 mPa · s

(2) Usability (Evaluation of stickiness)
An actual use test of stickiness when a test product was applied to the arms of 10 female panels was conducted. The evaluation criteria are as follows.
<Evaluation criteria>
A: Evaluated that 8 or more of 10 people were not sticky.
Δ: It was evaluated that 5 to 7 out of 10 people were sticky.
X: Evaluated that 8 or more out of 10 people were sticky.

[Test example]
Test products (Examples 1 to 4 and Comparative Examples 1 to 3) having the formulations shown in Tables 1 and 2 below were prepared according to a conventional method. That is, stearoxyhydroxypropylmethylcellulose is moistened with DPG (dipropylene glycol), dispersed in hot water using a portion of purified water, and after cooling, the remaining ingredients are mixed to prepare each test product. did.

  As a result, the examples satisfying the requirements of the blending component and the blending amount of the composition of the present invention gave good results for both the viscosity and the usability, but did not satisfy the blending component requirement of the blending component. In the comparative example, a problem was observed in viscosity or usability.

Hereinafter, formulation examples of the composition of the present invention are disclosed as examples.
[Example 5] Body gel for whitening
Compounding component amount (% by mass)
Stearoxyhydroxypropylmethylcellulose 0.5
Carbomer 0.4
Xanthan gum 0.2
Ethanol 20
Menthol 0.05
Ascorbyl glucoside 1
DPG 5
Glycerin 1
AMP 0.45
EDTA-2Na 0.05
Citric acid 0.03
Sodium citrate 0.17
Perfume Appropriate amount of purified water

<Manufacturing method>
Stearoxyhydroxypropylmethylcellulose is wetted with DPG, dispersed in hot water using a portion of purified water, cooled, and the remaining ingredients are mixed to prepare a whitening body gel.

[Example 6] Gel cream for whole body
Compounding component amount (% by mass)
Stearoxyhydroxypropylmethylcellulose 0.7
Carbomer 0.2
(Acrylic acid / alkyl acrylate (C10-30)) copolymer 0.08
Xanthan gum 0.2
Ethanol 35
Menthol 0.3
Pentaerythrityl tetraethylhexanoate 3
DPG 10
Glycerin 1
AMP 0.1
EDTA-2Na 0.05
Perfume Appropriate amount of purified water

<Manufacturing method>
Stearoxyhydroxypropyl methylcellulose is wetted with DPG, dispersed in hot water using a portion of purified water, and after cooling, the remaining ingredients are mixed to prepare a whole body gel cream.

[Example 7] Cool body gel for whole body
Compounding component amount (% by mass)
Stearoxyhydroxypropylmethylcellulose 0.5
Carbomer 0.25
Xanthan gum 0.2
Ethanol 35
PPG-20 decyltetradeces-10 0.2
Menthol 0.5
Peppermint oil 0.07
Caffeine 0.001
DPG 5
Glycerin 1
AMP 0.09
EDTA-2Na 0.05
Perfume Appropriate amount of purified water

<Manufacturing method>
Stearoxyhydroxypropylmethylcellulose is wetted with DPG, dispersed in hot water using a portion of purified water, and after cooling, the remaining ingredients are mixed to prepare a whole body cool body gel.

[Example 8] Slimming gel
Compounding component amount (% by mass)
Stearoxyhydroxypropylmethylcellulose 0.5
Carbomer 0.25
Xanthan gum 0.2
Ethanol 40
PPG-20 decyltetradeces-10 0.2
Menthol 0.5
Menthyl lactate 1
Caffeine 0.2
DPG 5
Glycerin 1
AMP 0.09
EDTA-2Na 0.05
Perfume Appropriate amount of purified water

<Manufacturing method>
Stearoxy hydroxypropyl methylcellulose is wetted with DPG, dispersed in hot water using a portion of purified water, and after cooling, the remaining ingredients are mixed to prepare a slimming gel.

Claims (9)

The gel external composition characterized by containing the component of following (1)-(5).
(1) ethanol is 20 to 50% by mass of the composition,
(2) 0.1-1% by mass of the hydrophobic modified alkyl cellulose,
(3) 0.1 to 0.5% by mass of the carboxyvinyl polymer or a salt thereof,
(4) a water-insoluble component,
(5) Water. The gel external composition according to claim 1, wherein the hydrophobically modified alkyl cellulose is stearoxyhydroxypropyl methylcellulose. Furthermore, the gel-form composition for external use of Claim 1 or 2 which contains 0.05-0.5 mass% of nonionic surfactants of a composition. The gel-like external composition according to claim 3, wherein the nonionic surfactant is a nonionic surfactant having an HLB value of 7 or more. The gel-like external composition according to claim 4, wherein the nonionic surfactant is a POE · POP-alkyl ether. The gelled external composition according to claim 5, wherein the POE · POP-alkyl ether is PPG-20decyltetradeceth-10. The water-insoluble component is one or two or more different components selected from the group consisting of a fragrance component, fats and oils, a refreshing agent, an oil-soluble drug, and a peptide. A gel-like external composition according to claim 1. The gel external composition according to any one of claims 1 to 7, which is a solubilized composition in which a water-insoluble component is solubilized. The gel external composition according to any one of claims 1 to 8, which is a body cosmetic.