IT201600122363A1 - COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY - Google Patents

COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY

Info

Publication number
IT201600122363A1
IT201600122363A1 IT102016000122363A IT201600122363A IT201600122363A1 IT 201600122363 A1 IT201600122363 A1 IT 201600122363A1 IT 102016000122363 A IT102016000122363 A IT 102016000122363A IT 201600122363 A IT201600122363 A IT 201600122363A IT 201600122363 A1 IT201600122363 A1 IT 201600122363A1
Authority
IT
Italy
Prior art keywords
nanoformulation
oncology
coordination
synthesis
compounds
Prior art date
Application number
IT102016000122363A
Other languages
Italian (it)
Inventor
Dolores Fregona
Chiara Nardon
Leonardo Brustolin
Nicolo' Pettenuzzo
Original Assignee
Dolores Fregona
Chiara Nardon
Leonardo Brustolin
Pettenuzzo Nicolo’
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dolores Fregona, Chiara Nardon, Leonardo Brustolin, Pettenuzzo Nicolo’ filed Critical Dolores Fregona
Priority to IT102016000122363A priority Critical patent/IT201600122363A1/en
Priority to PCT/IB2017/057593 priority patent/WO2018100561A1/en
Publication of IT201600122363A1 publication Critical patent/IT201600122363A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/12Gold compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT102016000122363A 2016-12-02 2016-12-02 COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY IT201600122363A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT102016000122363A IT201600122363A1 (en) 2016-12-02 2016-12-02 COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY
PCT/IB2017/057593 WO2018100561A1 (en) 2016-12-02 2017-12-02 Coordination compounds, syntheses, nanoformulation and use thereof in oncology

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102016000122363A IT201600122363A1 (en) 2016-12-02 2016-12-02 COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY

Publications (1)

Publication Number Publication Date
IT201600122363A1 true IT201600122363A1 (en) 2018-06-02

Family

ID=58545052

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102016000122363A IT201600122363A1 (en) 2016-12-02 2016-12-02 COMPOUNDS OF COORDINATION, SYNTHESIS, NANOFORMULATION AND USE OF THE SAME IN ONCOLOGY

Country Status (2)

Country Link
IT (1) IT201600122363A1 (en)
WO (1) WO2018100561A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI579296B (en) 2011-12-28 2017-04-21 Chugai Pharmaceutical Co Ltd Cyclization of Peptide Compounds
CN118772227A (en) 2017-06-09 2024-10-15 中外制药株式会社 Method for synthesizing peptides containing N-substituted amino acids
WO2019117274A1 (en) 2017-12-15 2019-06-20 中外製薬株式会社 Method for producing peptide, and method for processing bases
EP3727458A1 (en) 2017-12-18 2020-10-28 Auburn University Method for preparing stabilized metal ion ligand nanocomplex and compositions thereof
US11732002B2 (en) 2018-11-30 2023-08-22 Chugai Seiyaku Kabushiki Kaisha Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound
CN111384273B (en) * 2018-12-29 2021-07-16 Tcl科技集团股份有限公司 Quantum dot light-emitting diode and preparation method thereof
JP7472101B2 (en) 2019-03-15 2024-04-22 中外製薬株式会社 Method for producing aromatic amino acid derivatives
CN110408047B (en) * 2019-08-29 2020-06-23 中南大学 Nano coordination polymer and preparation method and application thereof
CN114702515B (en) * 2022-04-18 2023-08-01 中山大学 Gold (III) complex and application thereof in cancer light therapy

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010105691A1 (en) * 2009-03-20 2010-09-23 Universita' Degli Studi Di Padova Gold (iii) complexes with oligopeptides functionalized with sulfur donors and use thereof as antitumor agents

Family Cites Families (2)

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Publication number Priority date Publication date Assignee Title
US10082001B2 (en) 2012-03-09 2018-09-25 Halliburton Energy Services, Inc. Cement set activators for cement compositions and associated methods
ITPD20130236A1 (en) 2013-08-22 2015-02-23 Michele Back PHOTO-COMPOSITIONS, SYNTHESIS AND USE OF THE SAME

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010105691A1 (en) * 2009-03-20 2010-09-23 Universita' Degli Studi Di Padova Gold (iii) complexes with oligopeptides functionalized with sulfur donors and use thereof as antitumor agents

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
ALEX FRAGOSO ET AL: "Influence of Electrostatic Interactions and Hydrogen Bonding on the Activity of Cyclodextrin-based Superoxide Dismutase Models", SUPRAMOLECULAR CHEMISTRY., vol. 13, no. 5, 1 September 2001 (2001-09-01), US, pages 619 - 625, XP055374831, ISSN: 1061-0278, DOI: 10.1080/10610270108039795 *
BENIGNO MACIAS ET AL: "Copper complexes with dithiocarbamates derived from natural occurring amino acids. Crystal and molecular structure of [Cu(en)(EtOH)(H 2O) 3][Cu(dtc-pro) 2]", POLYHEDRON, 1 January 2002 (2002-01-01), pages 1899 - 1904, XP055366149, Retrieved from the Internet <URL:https://ac.els-cdn.com/S0277538702010987/1-s2.0-S0277538702010987-main.pdf?_tid=54114b32-2654-11e7-97ae-00000aab0f27&acdnat=1492753108_d69a0caee314a2d85d15d9530fde3868> DOI: 10.1016/S0277-5387(02)01098-7 *
CHIARA NARDON ET AL: "Gold(III)-pyrrolidinedithiocarbamato Derivatives as Antineoplastic Agents**", CHEMISTRYOPEN, 1 January 2015 (2015-01-01), pages 183 - 191, XP055366143, Retrieved from the Internet <URL:https://onlinelibrary.wiley.com/store/10.1002/open.201402091/asset/open201402091.pdf?v=1&t=j1reame9&s=f8c76ed7fc5fe7748002b80806c80d45168716ed> [retrieved on 20170421] *
DIAZ A ET AL: "Interactions of nitric ocide with copper (II) dithiocarbamates in aqueous solution", JOURNAL OF INORGANIC BIOCHEMISTRY, ELSEVIER INC, US, no. 95, 1 January 2003 (2003-01-01), pages 283 - 290, XP002335489, ISSN: 0162-0134, DOI: 10.1016/S0162-0134(03)00126-0 *
GIOVAGNINI LORENA ET AL: "Chemical and biological profiles of novel copper(II) complexes containing S-donor ligands for the treatment of cancer", INORGANIC CHEMISTRY UNITED ST,, vol. 47, no. 14, 21 July 2008 (2008-07-21), pages 6336 - 6343, XP009119369, DOI: 10.1021/IC800404E *
MORELLE NEGOM KOUODOM ET AL: "Rational design of gold(III)-dithiocarbamato peptidomimetics for the targeted anticancer chemotherapy", JOURNAL OF INORGANIC BIOCHEMISTRY, vol. 117, 1 December 2012 (2012-12-01), US, pages 248 - 260, XP055366138, ISSN: 0162-0134, DOI: 10.1016/j.jinorgbio.2012.07.001 *
MUHAMMAD ALTAF ET AL: "Synthesis, characterization and in vitro cytotoxicity of gold(III) dialkyl/diaryldithiocarbamato complexes", RSC ADVANCES: AN INTERNATIONAL JOURNAL TO FURTHER THE CHEMICAL SCIENCES, vol. 5, no. 99, 1 January 2015 (2015-01-01), GB, pages 81599 - 81607, XP055366145, ISSN: 2046-2069, DOI: 10.1039/C5RA15123F *
NAMI SHAHAB A A ET AL: "Synthesis, characterization, molecular docking and biological studies of self assembled transition metal dithiocarbamates of substituted pyrrole-2-carboxaldehyde", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B: BIOLOGY, ELSEVIER SCIENCE S.A., BASEL, CH, vol. 160, 11 May 2016 (2016-05-11), pages 392 - 399, XP029560439, ISSN: 1011-1344, DOI: 10.1016/J.JPHOTOBIOL.2016.05.010 *
ROBERTO CAO ET AL: "Gold Nanoparticles Enhancing Dismutation of Superoxide Radical by Its Bis(dithiocarbamato)copper(II) Shell", INORGANIC CHEMISTRY, vol. 50, no. 11, 6 June 2011 (2011-06-06), EASTON, US, pages 4705 - 4712, XP055366148, ISSN: 0020-1669, DOI: 10.1021/ic101770h *
RONCONI LUCA ET AL: "Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity", INORGANIC CHEMI, AMERICAN CHEMICAL SOCIETY, EASTON, US, vol. 44, no. 6, 21 March 2005 (2005-03-21), pages 1867 - 1881, XP009119371, ISSN: 0020-1669, DOI: 10.1021/IC048260V *
SHI YANAN ET AL: "Synthesis, characterization and cytotoxicity of the Au(III) complexes with cyclic amine-based dithiocarbamate ligands", INORGANIC CHEMISTRY COMMUNICATIONS, ELSEVIER, AMSTERDAM, NL, vol. 30, 14 February 2013 (2013-02-14), pages 178 - 181, XP029003773, ISSN: 1387-7003, DOI: 10.1016/J.INOCHE.2013.02.010 *

Also Published As

Publication number Publication date
WO2018100561A1 (en) 2018-06-07

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