IN2013MU03216A - - Google Patents

Info

Publication number
IN2013MU03216A
IN2013MU03216A IN3216MU2013A IN2013MU03216A IN 2013MU03216 A IN2013MU03216 A IN 2013MU03216A IN 3216MU2013 A IN3216MU2013 A IN 3216MU2013A IN 2013MU03216 A IN2013MU03216 A IN 2013MU03216A
Authority
IN
India
Prior art keywords
compounds
preventing
formula
preparation
disclosed
Prior art date
Application number
Inventor
Prasad Keshav Deshpande
Shivaji Sampatrao Pawar
Satish Bhavsar
Ravindra Dattatraya Yeole
Sachin Bhagwat
Mahesh Vithalbhai Patel
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Priority to CA2926773A priority Critical patent/CA2926773A1/en
Priority to EP14802150.4A priority patent/EP3055311B1/en
Priority to US15/027,790 priority patent/US9434728B1/en
Priority to JP2016521668A priority patent/JP6411482B2/en
Priority to CN201480066216.6A priority patent/CN106414444B/en
Priority to AU2014333436A priority patent/AU2014333436A1/en
Priority to MX2016004509A priority patent/MX2016004509A/en
Priority to IN3216MU2013 priority patent/IN2013MU03216A/en
Priority to RU2016113755A priority patent/RU2016113755A/en
Priority to PCT/IB2014/065195 priority patent/WO2015052682A1/en
Publication of IN2013MU03216A publication Critical patent/IN2013MU03216A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Compounds of Formula (I), their preparation and use in preventing or treating bacterial infections are disclosed.
IN3216MU2013 2013-10-11 2014-10-10 IN2013MU03216A (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
CA2926773A CA2926773A1 (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use
EP14802150.4A EP3055311B1 (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use
US15/027,790 US9434728B1 (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use
JP2016521668A JP6411482B2 (en) 2013-10-11 2014-10-10 Nitrogen-containing compounds and uses thereof
CN201480066216.6A CN106414444B (en) 2013-10-11 2014-10-10 Nitrogen-containing compound and their purposes
AU2014333436A AU2014333436A1 (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use
MX2016004509A MX2016004509A (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use.
IN3216MU2013 IN2013MU03216A (en) 2013-10-11 2014-10-10
RU2016113755A RU2016113755A (en) 2013-10-11 2014-10-10 NITROGEN-CONTAINING COMPOUNDS AND THEIR APPLICATION
PCT/IB2014/065195 WO2015052682A1 (en) 2013-10-11 2014-10-10 Nitrogen containing compounds and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN3216MU2013 IN2013MU03216A (en) 2013-10-11 2014-10-10

Publications (1)

Publication Number Publication Date
IN2013MU03216A true IN2013MU03216A (en) 2015-07-03

Family

ID=51945946

Family Applications (1)

Application Number Title Priority Date Filing Date
IN3216MU2013 IN2013MU03216A (en) 2013-10-11 2014-10-10

Country Status (10)

Country Link
US (1) US9434728B1 (en)
EP (1) EP3055311B1 (en)
JP (1) JP6411482B2 (en)
CN (1) CN106414444B (en)
AU (1) AU2014333436A1 (en)
CA (1) CA2926773A1 (en)
IN (1) IN2013MU03216A (en)
MX (1) MX2016004509A (en)
RU (1) RU2016113755A (en)
WO (1) WO2015052682A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106458896A (en) 2014-03-14 2017-02-22 沃克哈特有限公司 A process for preparation of sodium (2s, 5r)-6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate
WO2018053057A2 (en) * 2016-09-19 2018-03-22 Merck Sharp & Dohme Corp. Process for preparing beta-lactamase inhibitor hydroxylurea intermediates
JOP20190061A1 (en) * 2016-09-28 2019-03-26 Novartis Ag Beta-lactamase inhibitors
CN111138456A (en) * 2019-12-27 2020-05-12 山东安弘制药有限公司 Preparation method of cephamycin intermediate compound
WO2024227071A1 (en) * 2023-04-26 2024-10-31 Entasis Therapeutics Limited Synthesis of durlobactam

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2812635B1 (en) 2000-08-01 2002-10-11 Aventis Pharma Sa NOVEL HETEROCYCLIC COMPOUNDS, PREPARATION AND USE AS MEDICAMENTS IN PARTICULAR AS ANTI-BACTERIALS
EP2135959A1 (en) * 2008-06-19 2009-12-23 Novexel Use of (1R,2S,5R) 1,6-Diazabicyclo [3,2,1]octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases
FR2936798B1 (en) * 2008-10-03 2012-09-28 Novexel NOVEL HETEROCYCLIC NITROGEN COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIAL MEDICINES.
FR2936951B1 (en) 2008-10-10 2010-12-03 Novexel NOVEL COMBINATIONS OF ANTIBACTERIAL NITROGENIC HETEROCYCLIC COMPOUNDS WITH OTHER ANTIBACTERIAL COMPOUNDS AND THEIR USE AS MEDICAMENTS
FR2937034B1 (en) * 2008-10-10 2012-11-23 Novexel NOVEL HETEROCYCLIC NITROGEN COMPOUNDS, THEIR PREPARATION AND THEIR USE AS ANTIBACTERIAL MEDICINES
CA2846107C (en) * 2011-09-13 2016-06-21 Wockhardt Limited Nitrogen containing compounds and their use

Also Published As

Publication number Publication date
JP6411482B2 (en) 2018-10-24
EP3055311B1 (en) 2017-08-09
RU2016113755A (en) 2017-11-16
JP2016532661A (en) 2016-10-20
RU2016113755A3 (en) 2018-06-26
US9434728B1 (en) 2016-09-06
MX2016004509A (en) 2016-10-28
US20160257684A1 (en) 2016-09-08
EP3055311A1 (en) 2016-08-17
CN106414444A (en) 2017-02-15
CA2926773A1 (en) 2015-04-16
WO2015052682A1 (en) 2015-04-16
AU2014333436A1 (en) 2016-05-05
CN106414444B (en) 2018-02-02

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