IN167980B - - Google Patents

Info

Publication number
IN167980B
IN167980B IN1059/DEL/87A IN1059DE1987A IN167980B IN 167980 B IN167980 B IN 167980B IN 1059DE1987 A IN1059DE1987 A IN 1059DE1987A IN 167980 B IN167980 B IN 167980B
Authority
IN
India
Application number
IN1059/DEL/87A
Other languages
English (en)
Inventor
Edmund William Hafner
Kelvin Scott Holdom
Shin-Jen Edward Lee
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IN167980B publication Critical patent/IN167980B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C12P19/623Avermectin; Milbemycin; Ivermectin; C-076
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Fodder In General (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steroid Compounds (AREA)
IN1059/DEL/87A 1987-01-23 1987-12-10 IN167980B (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US651287A 1987-01-23 1987-01-23

Publications (1)

Publication Number Publication Date
IN167980B true IN167980B (fr) 1991-01-19

Family

ID=21721247

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1059/DEL/87A IN167980B (fr) 1987-01-23 1987-12-10

Country Status (30)

Country Link
EP (2) EP0276103B1 (fr)
JP (2) JPH0681757B2 (fr)
KR (2) KR900004419B1 (fr)
CN (1) CN1056883C (fr)
AR (1) AR241798A1 (fr)
AT (2) ATE96174T1 (fr)
AU (2) AU595673B2 (fr)
BG (1) BG51051A3 (fr)
BR (1) BR8800271A (fr)
CZ (1) CZ279782B6 (fr)
DD (2) DD290214A5 (fr)
DE (2) DE3884973T2 (fr)
DK (2) DK28988A (fr)
EG (1) EG18797A (fr)
ES (2) ES2059498T3 (fr)
FI (2) FI90091C (fr)
GR (1) GR3007586T3 (fr)
HU (2) HU201973B (fr)
IE (2) IE61483B1 (fr)
IL (2) IL85118A (fr)
IN (1) IN167980B (fr)
MA (1) MA21160A1 (fr)
MY (1) MY103514A (fr)
NZ (2) NZ223272A (fr)
PL (2) PL156764B1 (fr)
PT (2) PT86583B (fr)
RU (1) RU1806198C (fr)
SK (1) SK40788A3 (fr)
YU (1) YU47878B (fr)
ZA (3) ZA88447B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
US4874749A (en) * 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
EP0313297B1 (fr) * 1987-10-23 1993-05-19 Pfizer Inc. Procédé de production d'aglycones d'avermectine et des cultures les contenant
GB8807280D0 (en) * 1988-03-26 1988-04-27 Pfizer Ltd Antiparasitic agents
GB8811036D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
GB8815967D0 (en) * 1988-07-05 1988-08-10 Pfizer Ltd Antiparasitic agents
NZ231773A (en) * 1988-12-23 1992-09-25 Merck & Co Inc Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof
NZ231772A (en) * 1988-12-23 1992-11-25 Merck & Co Inc Avermectin derivatives, preparation and parasiticidal compositions thereof
US5015630A (en) * 1989-01-19 1991-05-14 Merck & Co., Inc. 5-oxime avermectin derivatives
US4897383A (en) * 1989-02-13 1990-01-30 Merck & Co., Inc. Avermectin derivatives
US5252474A (en) * 1989-03-31 1993-10-12 Merck & Co., Inc. Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use
US5057499A (en) * 1989-06-02 1991-10-15 Merck & Co. Inc. Avermectin derivatives
US5030622A (en) * 1989-06-02 1991-07-09 Merck & Co., Inc. Avermectin derivatives
US5023241A (en) * 1989-07-31 1991-06-11 Merck & Co., Inc. Avermectin derivatives
US5830875A (en) * 1989-10-30 1998-11-03 Merck & Co., Inc. 24-and 25-substituted avermectin and milbemycin derivatives
JP2888586B2 (ja) * 1990-03-05 1999-05-10 社団法人北里研究所 エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法
US5169839A (en) * 1990-05-11 1992-12-08 Merck & Co., Inc. Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections
US5208222A (en) * 1991-03-28 1993-05-04 Merck & Co., Inc. 4"-and 4'-alkylthio avermectin derivatives
US5240915A (en) * 1991-10-15 1993-08-31 Merck & Co., Inc. Avermectin derivatives
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
US5292647A (en) * 1992-11-30 1994-03-08 Eli Lilly And Company Strain of streptomyces for producing avermectins and processes therewith
CN1038330C (zh) * 1993-07-05 1998-05-13 塞泰克斯公司 阿弗麦菌素的生产与分离
PL181778B1 (pl) * 1993-07-30 2001-09-28 Pfizer Sposób wytwarzania naturalnej awermektyny PL PL
CN1040113C (zh) * 1993-10-05 1998-10-07 美国辉瑞有限公司 抗寄生虫药物多哇麦汀(doramectin)的中间体及其制备方法
FI942725A (fi) * 1993-12-16 1995-06-17 Pfizer Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta
US5701591A (en) * 1995-04-07 1997-12-23 Telecommunications Equipment Corporation Multi-function interactive communications system with circularly/elliptically polarized signal transmission and reception
NZ518657A (en) * 1998-02-13 2003-10-31 Pfizer Prod Inc Streptomyces hygroscopicus directing the ratio of B2:B1 avermectins
PL203818B1 (pl) * 1999-08-12 2009-11-30 Pfizer Prod Inc Cząsteczka polinukleotydowa, zrekombinowany wektor, komórka gospodarz Streptomyces, sposób wytwarzania nowego szczepu S. avermitilis, komórka Streptomyces avermitilis, sposób wytwarzania awermektyn i kompozycja awermektyn cykloheksylo-B2:cykloheksylo-B1
KR100415395B1 (ko) * 2000-08-02 2004-01-16 한국생명공학연구원 에버멕틴 bc-5-o-메칠트랜스퍼라제의 유전자가 파괴된 스트렙토마이세스 에버미티리스 변이균주 및 그의 제조 방법
RS50813B (sr) 2002-02-12 2010-08-31 Pfizer Products Inc. Streptomyces avermitilis gen koji određuje odnos b2:b1 avermektina
WO2023203038A1 (fr) 2022-04-19 2023-10-26 Syngenta Crop Protection Ag Lutte contre les insectes, les acariens et les nématodes nuisibles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4429042A (en) 1978-09-08 1984-01-31 Merck & Co., Inc. Strain of Streptomyces for producing antiparasitic compounds
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
GB8606120D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process

Also Published As

Publication number Publication date
YU47878B (sh) 1996-05-20
EP0276103A2 (fr) 1988-07-27
DD290214A5 (de) 1991-05-23
HU201973B (en) 1991-01-28
IE880160L (en) 1988-07-23
DE3884973T2 (de) 1994-02-17
ES2053719T3 (es) 1994-08-01
KR880009027A (ko) 1988-09-13
KR900004419B1 (ko) 1990-06-25
MY103514A (en) 1993-07-31
HUT47644A (en) 1989-03-28
EP0276131B1 (fr) 1993-04-07
CN88100649A (zh) 1988-10-26
DD267512A5 (de) 1989-05-03
FI880280A (fi) 1988-07-24
PL156763B1 (pl) 1992-04-30
DK28988A (da) 1988-07-24
EP0276131A3 (en) 1989-10-25
EP0276131A2 (fr) 1988-07-27
JPH0681757B2 (ja) 1994-10-19
AU1069688A (en) 1988-07-28
DE3879975T2 (de) 1993-07-15
PL270239A1 (en) 1989-06-26
CZ279782B6 (cs) 1995-06-14
AU7111091A (en) 1991-08-08
JPS63291576A (ja) 1988-11-29
FI880281A0 (fi) 1988-01-22
DE3884973D1 (de) 1993-11-25
BG51051A3 (en) 1993-01-15
RU1806198C (ru) 1993-03-30
ZA88449B (en) 1989-08-30
YU11988A (en) 1989-08-31
FI90088C (fi) 1993-12-27
HU200487B (en) 1990-06-28
FI90088B (fi) 1993-09-15
IL85118A0 (en) 1988-06-30
DK175720B1 (da) 2005-02-07
EP0276103B1 (fr) 1993-10-20
DK29088A (da) 1988-07-24
ATE96174T1 (de) 1993-11-15
PL270238A1 (en) 1989-06-26
HUT47978A (en) 1989-04-28
CZ40788A3 (en) 1994-12-15
AU595673B2 (en) 1990-04-05
DE3879975D1 (de) 1993-05-13
DK29088D0 (da) 1988-01-22
PT86583B (pt) 1991-12-31
PT86584A (en) 1988-02-01
FI90091C (fi) 1993-12-27
JPS63270684A (ja) 1988-11-08
KR910002225B1 (ko) 1991-04-08
ZA88447B (en) 1989-08-30
CN1056883C (zh) 2000-09-27
KR880009122A (ko) 1988-09-14
PT86584B (pt) 1991-12-31
NZ223272A (en) 1989-12-21
BR8800271A (pt) 1988-09-06
FI90091B (fi) 1993-09-15
EG18797A (en) 1994-06-30
AU631298B2 (en) 1992-11-19
PL156764B1 (pl) 1992-04-30
IE61066B1 (en) 1994-09-21
ES2059498T3 (es) 1994-11-16
NZ223271A (en) 1991-12-23
SK279351B6 (sk) 1998-10-07
FI880280A0 (fi) 1988-01-22
IL85165A (en) 1992-07-15
MA21160A1 (fr) 1988-10-01
GR3007586T3 (fr) 1993-08-31
JPH0817693B2 (ja) 1996-02-28
ATE87927T1 (de) 1993-04-15
IE61483B1 (en) 1994-11-02
AR241798A1 (es) 1992-12-30
EP0276103A3 (en) 1989-11-08
PT86583A (en) 1988-02-01
SK40788A3 (en) 1998-10-07
IL85118A (en) 1993-01-31
AU1074288A (en) 1988-07-28
IE880161L (en) 1988-07-23
ZA88448B (en) 1989-08-30
AU603416B2 (en) 1990-11-15
FI880281A (fi) 1988-07-24
IL85165A0 (en) 1988-07-31
DK28988D0 (da) 1988-01-22

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