IL87902A0 - Soluble human cd4 fragments and applications thereof - Google Patents

Soluble human cd4 fragments and applications thereof

Info

Publication number
IL87902A0
IL87902A0 IL87902A IL8790288A IL87902A0 IL 87902 A0 IL87902 A0 IL 87902A0 IL 87902 A IL87902 A IL 87902A IL 8790288 A IL8790288 A IL 8790288A IL 87902 A0 IL87902 A0 IL 87902A0
Authority
IL
Israel
Prior art keywords
fragments
applications
soluble human
soluble
human
Prior art date
Application number
IL87902A
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/217,475 external-priority patent/US5109123A/en
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of IL87902A0 publication Critical patent/IL87902A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL87902A 1987-10-08 1988-10-04 Soluble human cd4 fragments and applications thereof IL87902A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10618587A 1987-10-08 1987-10-08
US14431388A 1988-01-14 1988-01-14
US20658588A 1988-06-14 1988-06-14
US07/217,475 US5109123A (en) 1988-06-14 1988-07-11 Alteration of ability of soluble CD4 fragments to bind HIV

Publications (1)

Publication Number Publication Date
IL87902A0 true IL87902A0 (en) 1989-03-31

Family

ID=27493499

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87902A IL87902A0 (en) 1987-10-08 1988-10-04 Soluble human cd4 fragments and applications thereof

Country Status (9)

Country Link
EP (1) EP0400010A1 (en)
JP (1) JPH03504234A (en)
AU (1) AU2614888A (en)
DK (1) DK87490A (en)
ES (1) ES2012129A6 (en)
GR (1) GR1000850B (en)
IL (1) IL87902A0 (en)
NZ (1) NZ226475A (en)
WO (1) WO1989003222A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637677A (en) 1987-07-16 1997-06-10 The Trustees Of The University Of Pennsylvania Biologically active compounds and methods of constructing and using the same
ZA887365B (en) * 1987-10-02 1990-05-30 Genentech Inc Adheson variants
US5206353A (en) * 1988-07-23 1993-04-27 The United States Of America As Represented By The Department Of Health And Human Services CD-4/cytotoxic gene fusions
AU623924B2 (en) * 1988-07-22 1992-05-28 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Cytotoxic agent against specific virus infection
EP0408372A1 (en) * 1989-07-13 1991-01-16 Smithkline Beecham Corporation Anti-viral therapy
KR927003613A (en) * 1989-08-23 1992-12-18 더 제너랄 호스피탈 코오퍼레이숀 CD4 polypeptides, glycosylated human CD4 molecules, fragments thereof, fusion proteins, gene sequences, and uses thereof of non-human primates
US5614612A (en) * 1990-03-09 1997-03-25 Haigwood; Nancy L. Purified gp120 compositions retaining natural conformation
JPH0725794B2 (en) * 1990-03-23 1995-03-22 呉羽化学工業株式会社 Novel peptide
CA2091258A1 (en) * 1990-09-14 1992-03-15 William Williams Design of bioactive peptides based on immunoglobulin structure
AU1438592A (en) * 1991-02-08 1992-09-07 Progenics Pharmaceuticals, Inc. Cd4-gamma1 and cd4-igg1 chimeras
US7070991B2 (en) 1991-02-08 2006-07-04 Progenics Pharmaceuticals, Inc. Cells expressing a CD4-IgG2 chimeric heterotetramer
EP1340769B1 (en) 1991-02-08 2005-02-09 Progenics Pharmaceuticals, Inc. CD4-gamma2 and CD4-IgG2 chimeras
US5234905A (en) * 1991-02-22 1993-08-10 University Of Colorado Foundation, Inc. Soluble CD4 molecules modified to prolong circulating half-life
EP0510483A1 (en) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Method for the detection of viruses
CA2360347C (en) 1998-12-31 2013-05-07 Chiron Corporation Improved expression of hiv polypeptides and production of virus-like particles
US7935805B1 (en) 1998-12-31 2011-05-03 Novartis Vaccines & Diagnostics, Inc Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof
JP4776075B2 (en) 1998-12-31 2011-09-21 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Modified HIVENV polypeptide
WO2000039304A2 (en) 1998-12-31 2000-07-06 Chiron Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
JP5033303B2 (en) 2001-07-05 2012-09-26 ノバルティス バクシンズ アンド ダイアグノスティックス，インコーポレーテッド Polynucleotides encoding polypeptides with antigenic type C HIV, polypeptides and uses thereof
US20030170614A1 (en) 2001-08-31 2003-09-11 Megede Jan Zur Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof
JP2005521380A (en) 2001-08-31 2005-07-21 カイロン コーポレイション Polynucleotide encoding antigenic type B HIV polypeptide, polypeptide and use thereof
WO2014150748A2 (en) 2013-03-15 2014-09-25 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Stabilized single human cd4 domains and fusion proteins
WO2017055522A1 (en) 2015-09-29 2017-04-06 Academisch Medisch Centrum Stabilized env proteins of hiv

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3134874B2 (en) * 1986-08-21 2001-02-13 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク Use of DNA encoding T cell surface protein T4 and T4 fragment for AIDS treatment
PT88641B (en) * 1987-10-02 1993-04-30 Genentech Inc METHOD FOR PREPARING A VARIETY OF ADHESION

Also Published As

Publication number Publication date
DK87490A (en) 1990-06-08
ES2012129A6 (en) 1990-03-01
WO1989003222A1 (en) 1989-04-20
GR1000850B (en) 1993-02-17
JPH03504234A (en) 1991-09-19
EP0400010A1 (en) 1990-12-05
NZ226475A (en) 1991-03-26
DK87490D0 (en) 1990-04-06
AU2614888A (en) 1989-05-02

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