IL87563A - Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents

Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Info

Publication number
IL87563A
IL87563A IL87563A IL8756388A IL87563A IL 87563 A IL87563 A IL 87563A IL 87563 A IL87563 A IL 87563A IL 8756388 A IL8756388 A IL 8756388A IL 87563 A IL87563 A IL 87563A
Authority
IL
Israel
Prior art keywords
isoxazole
processes
preparation
same
pharmaceutical compositions
Prior art date
Application number
IL87563A
Other languages
English (en)
Other versions
IL87563A0 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK449887A external-priority patent/DK449887D0/da
Priority claimed from DE19873730667 external-priority patent/DE3730667A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL87563A0 publication Critical patent/IL87563A0/xx
Publication of IL87563A publication Critical patent/IL87563A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL87563A 1987-08-28 1988-08-25 Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same IL87563A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK449887A DK449887D0 (da) 1987-08-28 1987-08-28 Beta-carbolinderivater, deres fremstilling og anvendelse
DE19873730667 DE3730667A1 (de) 1987-09-09 1987-09-09 Neue ss-carboline

Publications (2)

Publication Number Publication Date
IL87563A0 IL87563A0 (en) 1989-01-31
IL87563A true IL87563A (en) 1993-08-18

Family

ID=25859709

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87563A IL87563A (en) 1987-08-28 1988-08-25 Isoxazole-b-carboline derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same

Country Status (15)

Country Link
US (1) US4933345A (pt)
EP (1) EP0305322B1 (pt)
JP (1) JP2690329B2 (pt)
AU (1) AU619203B2 (pt)
CA (1) CA1324382C (pt)
DE (1) DE3888428D1 (pt)
ES (1) ES2061716T3 (pt)
FI (1) FI88160C (pt)
HU (1) HU203101B (pt)
IE (1) IE65712B1 (pt)
IL (1) IL87563A (pt)
NO (1) NO167287C (pt)
NZ (1) NZ225959A (pt)
PT (1) PT88351B (pt)
RU (1) RU1836369C (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4118741A1 (de) * 1991-06-05 1992-12-10 Schering Ag Neue hetaryloxy-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
DE4120109A1 (de) * 1991-06-15 1992-12-17 Schering Ag 3-aryl- oder 3-hetaryl-(beta)-carboline, deren herstellung und verwendung in arzneimitteln
US5543519A (en) * 1991-06-15 1996-08-06 Schering Aktiengesellschaft 3-aryl or 3-hetaryl-β-carbolines, their production and use in pharmaceutical agents
DE4130933A1 (de) * 1991-09-13 1993-03-18 Schering Ag Neue (beta)-carbolinderivate, deren herstellung und verwendung in arzneimitteln
JP3108483B2 (ja) * 1991-09-30 2000-11-13 日清製粉株式会社 インドール誘導体およびこれを有効成分とする抗潰瘍薬
DE4330175A1 (de) * 1993-08-31 1995-03-02 Schering Ag Alkoxy-substituierte beta-Carboline
US9149465B2 (en) * 2009-05-18 2015-10-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8765735B2 (en) * 2009-05-18 2014-07-01 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
US8927551B2 (en) * 2009-05-18 2015-01-06 Infinity Pharmaceuticals, Inc. Isoxazolines as inhibitors of fatty acid amide hydrolase
FR2953838B1 (fr) * 2009-12-10 2012-02-24 Sanofi Aventis Derives de 9h-beta-carboline (ou 9h-pyridino[3,4-b]indole) trisubstitues, leur preparation et leur utilisation therapeutique
FR2953837B1 (fr) * 2009-12-10 2012-03-09 Sanofi Aventis Derives 9h-pyridino[3,4-b]indole disubstitues, leur preparation et leur utilisation therapeutique
US10947253B2 (en) 2019-08-05 2021-03-16 Ankh Life Sciences Limited Fused polycyclic dimers
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3240514A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Ss-carboline, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3240511A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von ss-carbolinderivaten
DE3240513A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung
DE3322895A1 (de) * 1983-06-23 1985-01-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s)
DK240084D0 (da) * 1984-05-15 1984-05-15 Ferrosan As New beta-carboline-3-oxadiazolyl derivatives
DE3535927A1 (de) * 1985-10-04 1987-04-09 Schering Ag 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel
DE3608089A1 (de) * 1986-03-08 1987-09-10 Schering Ag Heteroaryl-oxy-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
NO167287C (no) 1991-10-23
FI883963A0 (fi) 1988-08-26
NO883833L (no) 1989-03-01
IE882600L (en) 1989-02-28
IL87563A0 (en) 1989-01-31
IE65712B1 (en) 1995-11-15
ES2061716T3 (es) 1994-12-16
FI88160B (fi) 1992-12-31
NO167287B (no) 1991-07-15
HUT48244A (en) 1989-05-29
EP0305322A3 (en) 1990-04-04
PT88351B (pt) 1995-03-31
NZ225959A (en) 1991-02-26
FI883963A (fi) 1989-03-01
PT88351A (pt) 1989-06-30
HU203101B (en) 1991-05-28
CA1324382C (en) 1993-11-16
EP0305322B1 (de) 1994-03-16
EP0305322A2 (de) 1989-03-01
RU1836369C (ru) 1993-08-23
NO883833D0 (no) 1988-08-26
US4933345A (en) 1990-06-12
FI88160C (fi) 1993-04-13
DE3888428D1 (de) 1994-04-28
JPS6468370A (en) 1989-03-14
AU2150088A (en) 1989-03-02
JP2690329B2 (ja) 1997-12-10
AU619203B2 (en) 1992-01-23

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Legal Events

Date Code Title Description
KB Patent renewed
RH Patent void
MM9K Patent not in force due to non-payment of renewal fees