IL162431A0 - Corticotropin releasing factor 2 receptor agonists - Google Patents

Corticotropin releasing factor 2 receptor agonists

Info

Publication number: IL162431A0
Authority: IL; Israel
Prior art keywords: receptor agonists; releasing factor; corticotropin releasing; corticotropin; factor
Prior art date: 2002-01-16

Application number

IL16243103A

Other languages

English (en)

Original Assignee

Procter & Gamble

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-16

Filing date

2003-01-16

Publication date

2005-11-20

2003-01-16 Application filed by Procter & Gamble filed Critical Procter & Gamble

2005-11-20 Publication of IL162431A0 publication Critical patent/IL162431A0/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Endocrinology (AREA)
Gastroenterology & Hepatology (AREA)
Neurology (AREA)
Molecular Biology (AREA)
Physical Education & Sports Medicine (AREA)
Toxicology (AREA)
Zoology (AREA)
Orthopedic Medicine & Surgery (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Immunology (AREA)
Epidemiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

IL16243103A 2002-01-16 2003-01-16 Corticotropin releasing factor 2 receptor agonists IL162431A0 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US34911702P	2002-01-16	2002-01-16
US37633702P	2002-04-29	2002-04-29
US38889502P	2002-06-14	2002-06-14
US41198802P	2002-09-19	2002-09-19
PCT/US2003/001461 WO2003062269A2 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor receptor 2 agonists

Publications (1)

Publication Number	Publication Date
IL162431A0 true IL162431A0 (en)	2005-11-20

Family

ID=27617822

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
IL16243103A IL162431A0 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor 2 receptor agonists
IL15252903A IL162529A0 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor 2 receptor agonists
IL16253003A IL162530A0 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor receptor 2 agonists
IL196384A IL196384A0 (en)	2002-01-16	2009-01-07	Corticotropin releasing factor 2 receptor agonists
IL197774A IL197774A0 (en)	2002-01-16	2009-03-24	Corticotropin releasing factor 2 receptor agonists

Family Applications After (4)

Application Number	Title	Priority Date	Filing Date
IL15252903A IL162529A0 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor 2 receptor agonists
IL16253003A IL162530A0 (en)	2002-01-16	2003-01-16	Corticotropin releasing factor receptor 2 agonists
IL196384A IL196384A0 (en)	2002-01-16	2009-01-07	Corticotropin releasing factor 2 receptor agonists
IL197774A IL197774A0 (en)	2002-01-16	2009-03-24	Corticotropin releasing factor 2 receptor agonists

Country Status (30)

Country	Link
US (7)	US7192924B2 (zh)
EP (4)	EP1724283B1 (zh)
JP (3)	JP4508648B2 (zh)
KR (3)	KR100758858B1 (zh)
CN (3)	CN100475844C (zh)
AR (3)	AR038143A1 (zh)
AT (4)	ATE398632T1 (zh)
AU (2)	AU2003205197B2 (zh)
BR (3)	BR0306878A (zh)
CA (3)	CA2470743C (zh)
CY (1)	CY1106133T1 (zh)
DE (4)	DE60318547T2 (zh)
DK (2)	DK1465921T3 (zh)
ES (4)	ES2309909T3 (zh)
HK (1)	HK1078095A1 (zh)
IL (5)	IL162431A0 (zh)
MA (3)	MA27590A1 (zh)
MX (3)	MXPA04006885A (zh)
MY (1)	MY140306A (zh)
NO (3)	NO20043366L (zh)
NZ (3)	NZ533599A (zh)
PE (3)	PE20030849A1 (zh)
PL (3)	PL373529A1 (zh)
PT (2)	PT1465921E (zh)
RU (1)	RU2294333C2 (zh)
SA (3)	SA03230565B1 (zh)
SI (1)	SI1465921T1 (zh)
TW (3)	TW200302278A (zh)
WO (3)	WO2003062269A2 (zh)
ZA (1)	ZA200404995B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2427490A1 (en) *	2000-09-22	2002-03-28	Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V.	Methods for improving the antagonistic/agonistic properties of peptidic antagonists/agonists of the corticotropin-releasing factor receptor (crfr)
US7192924B2 (en) *	2002-01-16	2007-03-20	The Procter & Gamble Company	Corticotropin releasing factor 2 receptor agonists
WO2005103690A2 (en) *	2004-04-24	2005-11-03	Bayer Healthcare Ag	Diagnostics and therapeutics for diseases associated with corticotropin releasing hormone receptor 2 (crhr2)
MX2007012057A (es) *	2005-03-30	2007-11-23	Novartis Vaccines & Diagnostic	Haemophilus influenzae tipo b.
WO2007090087A2 (en) *	2006-01-27	2007-08-09	Research Development Foundation	Use of corticotropin releasing factor receptor-2 inhibitors for treating insulin-related diseases
US20100184674A1 (en) *	2007-09-11	2010-07-22	Dorian Bevec	Proadrenomedullin alone or in combination with big gastrin i as a therapeutic agent
EP2187937A1 (en) *	2007-09-11	2010-05-26	Mondobiotech Laboratories AG	Use of the peptide pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys as a therapeutic agent
WO2009046874A1 (en) *	2007-09-11	2009-04-16	Mondobiotech Laboratories Ag	Therapeutic combination of trh-potentiating peptide and stresscopin
BRPI0921640A2 (pt) *	2008-11-04	2019-09-24	Janssen Pharmaceutica Nv	agonistas peptídicos do crhr2 e usos do mesmo
EP2206726A1 (en) *	2009-01-08	2010-07-14	Universite Joseph Fourier	Non-invasive tools for detecting vulnerable atherosclerotic plaques
US20110105397A1 (en) *	2009-11-04	2011-05-05	Gengo Peter J	Method for treating heart failure with stresscopin-like peptides
WO2013063046A1 (en)	2011-10-24	2013-05-02	Research Development Foundation	Methods for increasing insulin secretion by co-stimulation of corticotropin-releasing factor receptors
US20150118287A1 (en)	2012-02-14	2015-04-30	The Regents Of The University Of California	Systemic delivery and regulated expression of paracrine genes for cardiovascular diseases and other conditions
JOP20170153A1 (ar) *	2016-07-15	2019-01-30	Lilly Co Eli	نظائر urocortin-2 جديدة معدلة بحمض دهني لعلاج داء السكري وأمراض الكلى المزمنة
KR20190084055A (ko) *	2016-10-20	2019-07-15	코르텐 인코포레이티드	부적응 스트레스 반응에서 기인한 질환의 치료 방법
CN110755434B (zh) *	2018-07-27	2022-03-15	中国医学科学院药物研究所	化合物palosuran防治骨骼肌萎缩等疾病的用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5235036A (en)	1991-05-31	1993-08-10	The Salk Institute For Biological Studies	Crf analogs
EP0860501A3 (en)	1994-06-14	1999-05-19	Neurocrine Biosciences, Inc.	Corticotropin-releasing factor2 receptors
US5786203A (en)	1994-06-14	1998-07-28	Neurocrine Biosciences, Inc.	Isolated nucleic acid encoding corticotropin-releasing factor2 receptors
US5824771A (en)	1994-12-12	1998-10-20	The Salk Institute For Biological Studies	Cyclic CRF agonists
US5663292A (en)	1994-12-12	1997-09-02	The Salk Institute For Biological Studies	Cyclic CRF analogs
US5660824A (en)	1995-05-24	1997-08-26	Grabstein; Kenneth H.	Muscle trophic factor
WO1997000063A2 (en)	1995-06-13	1997-01-03	The Salk Institute For Biological Studies	Urocortin peptides
US5869450A (en)	1996-03-06	1999-02-09	The Regents Of The University Of California	Anti-inflammatory compositions and method with corticotropin-releasing factor analogs
KR100879232B1 (ko)	2000-08-04	2009-01-20	리서치 디벨럽먼트 파운데이션	우로코르틴 단백질 및 이를 포함하는 약제학적 조성물
US20020082409A1 (en)	2000-10-26	2002-06-27	Hsu Sheau Yu	Stresscopins and their uses
US6670140B2 (en) *	2001-03-06	2003-12-30	The Procter & Gamble Company	Methods for identifying compounds for regulating muscle mass or function using corticotropin releasing factor receptors
US7192924B2 (en)	2002-01-16	2007-03-20	The Procter & Gamble Company	Corticotropin releasing factor 2 receptor agonists

2002
- 2002-12-11 US US10/317,251 patent/US7192924B2/en not_active Expired - Fee Related
- 2002-12-11 US US10/317,252 patent/US6936585B2/en not_active Expired - Lifetime
- 2002-12-11 US US10/315,964 patent/US7192923B2/en not_active Expired - Fee Related
2003
- 2003-01-10 TW TW092100535A patent/TW200302278A/zh unknown
- 2003-01-10 TW TW092100533A patent/TWI300442B/zh not_active IP Right Cessation
- 2003-01-10 TW TW092100532A patent/TW200302276A/zh unknown
- 2003-01-14 PE PE2003000041A patent/PE20030849A1/es not_active Application Discontinuation
- 2003-01-14 PE PE2003000040A patent/PE20030974A1/es not_active Application Discontinuation
- 2003-01-14 PE PE2003000039A patent/PE20030747A1/es not_active Application Discontinuation
- 2003-01-15 AR ARP030100100A patent/AR038143A1/es unknown
- 2003-01-15 AR ARP030100101A patent/AR038144A1/es unknown
- 2003-01-15 AR ARP030100099A patent/AR038142A1/es unknown
- 2003-01-15 MY MYPI20030136A patent/MY140306A/en unknown
- 2003-01-16 PL PL03373529A patent/PL373529A1/xx not_active Application Discontinuation
- 2003-01-16 KR KR1020047011057A patent/KR100758858B1/ko not_active IP Right Cessation
- 2003-01-16 ES ES06117810T patent/ES2309909T3/es not_active Expired - Lifetime
- 2003-01-16 ES ES03731965T patent/ES2287484T3/es not_active Expired - Lifetime
- 2003-01-16 AT AT06117810T patent/ATE398632T1/de not_active IP Right Cessation
- 2003-01-16 IL IL16243103A patent/IL162431A0/xx unknown
- 2003-01-16 NZ NZ533599A patent/NZ533599A/en unknown
- 2003-01-16 EP EP06117810A patent/EP1724283B1/en not_active Expired - Lifetime
- 2003-01-16 CN CNB038023520A patent/CN100475844C/zh not_active Expired - Fee Related
- 2003-01-16 AT AT03731965T patent/ATE362488T1/de not_active IP Right Cessation
- 2003-01-16 DK DK03703867T patent/DK1465921T3/da active
- 2003-01-16 CN CNB038023644A patent/CN100391972C/zh not_active Expired - Fee Related
- 2003-01-16 PT PT03703867T patent/PT1465921E/pt unknown
- 2003-01-16 JP JP2003562145A patent/JP4508648B2/ja not_active Expired - Fee Related
- 2003-01-16 MX MXPA04006885A patent/MXPA04006885A/es active IP Right Grant
- 2003-01-16 PL PL03371364A patent/PL371364A1/xx unknown
- 2003-01-16 IL IL15252903A patent/IL162529A0/xx unknown
- 2003-01-16 KR KR1020047011051A patent/KR100735586B1/ko not_active IP Right Cessation
- 2003-01-16 RU RU2004124847/13A patent/RU2294333C2/ru active
- 2003-01-16 NZ NZ533600A patent/NZ533600A/en unknown
- 2003-01-16 AU AU2003205197A patent/AU2003205197B2/en not_active Ceased
- 2003-01-16 BR BR0306878-1A patent/BR0306878A/pt not_active IP Right Cessation
- 2003-01-16 KR KR1020047011052A patent/KR100758857B1/ko not_active IP Right Cessation
- 2003-01-16 PT PT03731965T patent/PT1465923E/pt unknown
- 2003-01-16 AT AT03731963T patent/ATE383372T1/de not_active IP Right Cessation
- 2003-01-16 JP JP2003562154A patent/JP4489434B2/ja not_active Expired - Fee Related
- 2003-01-16 ES ES03731963T patent/ES2299701T3/es not_active Expired - Lifetime
- 2003-01-16 NZ NZ533598A patent/NZ533598A/en unknown
- 2003-01-16 EP EP03731965A patent/EP1465923B1/en not_active Expired - Lifetime
- 2003-01-16 DE DE60318547T patent/DE60318547T2/de not_active Expired - Lifetime
- 2003-01-16 SI SI200330360T patent/SI1465921T1/sl unknown
- 2003-01-16 CA CA2470743A patent/CA2470743C/en not_active Expired - Fee Related
- 2003-01-16 AT AT03703867T patent/ATE334147T1/de not_active IP Right Cessation
- 2003-01-16 CA CA2470656A patent/CA2470656C/en not_active Expired - Fee Related
- 2003-01-16 AU AU2003237419A patent/AU2003237419B2/en not_active Ceased
- 2003-01-16 MX MXPA04006884A patent/MXPA04006884A/es active IP Right Grant
- 2003-01-16 WO PCT/US2003/001461 patent/WO2003062269A2/en active IP Right Grant
- 2003-01-16 IL IL16253003A patent/IL162530A0/xx unknown
- 2003-01-16 WO PCT/US2003/001451 patent/WO2003062268A2/en active IP Right Grant
- 2003-01-16 WO PCT/US2003/001454 patent/WO2003062277A1/en active IP Right Grant
- 2003-01-16 EP EP03731963A patent/EP1465922B1/en not_active Expired - Lifetime
- 2003-01-16 CA CA2470731A patent/CA2470731C/en not_active Expired - Fee Related
- 2003-01-16 MX MXPA04006883A patent/MXPA04006883A/es active IP Right Grant
- 2003-01-16 DE DE60313845T patent/DE60313845T2/de not_active Expired - Lifetime
- 2003-01-16 DE DE60321730T patent/DE60321730D1/de not_active Expired - Lifetime
- 2003-01-16 BR BR0306826-9A patent/BR0306826A/pt not_active IP Right Cessation
- 2003-01-16 CN CNA038023709A patent/CN1617887A/zh active Pending
- 2003-01-16 PL PL03373139A patent/PL373139A1/xx not_active Application Discontinuation
- 2003-01-16 BR BR0306838-2A patent/BR0306838A/pt not_active Application Discontinuation
- 2003-01-16 EP EP03703867A patent/EP1465921B1/en not_active Expired - Lifetime
- 2003-01-16 DE DE60307044T patent/DE60307044T2/de not_active Expired - Lifetime
- 2003-01-16 JP JP2003562146A patent/JP4508649B2/ja not_active Expired - Fee Related
- 2003-01-16 ES ES03703867T patent/ES2269976T3/es not_active Expired - Lifetime
- 2003-01-16 DK DK03731965T patent/DK1465923T3/da active
- 2003-03-01 SA SA3230565A patent/SA03230565B1/ar unknown
- 2003-03-01 SA SA3230564A patent/SA03230564B1/ar unknown
- 2003-03-01 SA SA03230564D patent/SA03230564A/ar unknown
2004
- 2004-06-24 ZA ZA2004/04995A patent/ZA200404995B/en unknown
- 2004-07-13 MA MA27778A patent/MA27590A1/fr unknown
- 2004-07-13 MA MA27779A patent/MA27591A1/fr unknown
- 2004-07-13 MA MA27780A patent/MA27592A1/fr unknown
- 2004-08-13 NO NO20043366A patent/NO20043366L/no not_active Application Discontinuation
- 2004-08-13 NO NO20043371A patent/NO20043371L/no not_active Application Discontinuation
- 2004-08-16 NO NO20043396A patent/NO20043396L/no not_active Application Discontinuation
2005
- 2005-05-04 US US11/121,612 patent/US7462597B2/en not_active Expired - Fee Related
- 2005-11-11 HK HK05110114A patent/HK1078095A1/xx not_active IP Right Cessation
2006
- 2006-07-28 CY CY20061101051T patent/CY1106133T1/el unknown
2007
- 2007-02-02 US US11/701,576 patent/US7608701B2/en not_active Expired - Fee Related
- 2007-02-02 US US11/701,912 patent/US7632933B2/en not_active Expired - Fee Related
2009
- 2009-01-07 IL IL196384A patent/IL196384A0/en unknown
- 2009-03-24 IL IL197774A patent/IL197774A0/en unknown
- 2009-10-26 US US12/605,718 patent/US7897731B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60313845T2 (de)	2008-01-31
JP2005521387A (ja)	2005-07-21
NO20043371L (no)	2004-10-06
US20030148956A1 (en)	2003-08-07
MY140306A (en)	2009-12-31
DE60313845D1 (de)	2007-06-28
CA2470656C (en)	2011-06-28
TW200302276A (en)	2003-08-01
US7897731B2 (en)	2011-03-01
CA2470743A1 (en)	2003-07-31
DK1465921T3 (da)	2006-11-27
DE60318547D1 (de)	2008-02-21
AU2003205197B2 (en)	2006-03-02
KR20040082390A (ko)	2004-09-24
MXPA04006884A (es)	2004-12-06
WO2003062268A2 (en)	2003-07-31
ATE334147T1 (de)	2006-08-15
ATE398632T1 (de)	2008-07-15
CA2470743C (en)	2011-12-13
AU2003237419B2 (en)	2006-04-13
NZ533600A (en)	2007-02-23
NO20043396L (no)	2004-10-06
JP2005525101A (ja)	2005-08-25
US20060025339A1 (en)	2006-02-02
SA03230564B1 (ar)	2006-10-31
PE20030747A1 (es)	2003-10-23
CN100391972C (zh)	2008-06-04
US7192924B2 (en)	2007-03-20
CN1617887A (zh)	2005-05-18
ATE362488T1 (de)	2007-06-15
WO2003062269A3 (en)	2003-11-06
CA2470731C (en)	2011-06-21
SA03230565B1 (ar)	2006-10-31
EP1465923A1 (en)	2004-10-13
EP1724283B1 (en)	2008-06-18
SA03230565A (ar)	2005-12-03
IL196384A0 (en)	2011-07-31
EP1465921A2 (en)	2004-10-13
IL162530A0 (en)	2005-11-20
US6936585B2 (en)	2005-08-30
BR0306878A (pt)	2004-10-26
CY1106133T1 (el)	2011-06-08
EP1724283A2 (en)	2006-11-22
ES2299701T3 (es)	2008-06-01
MA27590A1 (fr)	2005-11-01
WO2003062269A2 (en)	2003-07-31
US7462597B2 (en)	2008-12-09
PT1465923E (pt)	2007-08-06
SI1465921T1 (sl)	2006-10-31
US7632933B2 (en)	2009-12-15
WO2003062277A1 (en)	2003-07-31
EP1465922B1 (en)	2008-01-09
MA27592A1 (fr)	2005-11-01
HK1078095A1 (en)	2006-03-03
SA03230564A (ar)	2005-12-03
IL162529A0 (en)	2005-11-20
US20030148957A1 (en)	2003-08-07
ZA200404995B (en)	2005-06-29
US20100197579A1 (en)	2010-08-05
EP1465923B1 (en)	2007-05-16
ES2287484T3 (es)	2007-12-16
PT1465921E (pt)	2006-12-29
MXPA04006883A (es)	2004-12-06
PE20030849A1 (es)	2003-12-01
MA27591A1 (fr)	2005-11-01
KR100758858B1 (ko)	2007-09-14
RU2294333C2 (ru)	2007-02-27
KR100758857B1 (ko)	2007-09-14
MXPA04006885A (es)	2004-12-06
US7608701B2 (en)	2009-10-27
AR038143A1 (es)	2004-12-29
CN1617886A (zh)	2005-05-18
CN1617885A (zh)	2005-05-18
IL197774A0 (en)	2009-12-24
AR038144A1 (es)	2004-12-29
KR20040082392A (ko)	2004-09-24
BR0306826A (pt)	2005-09-06
AR038142A1 (es)	2004-12-29
EP1724283A3 (en)	2007-04-11
EP1465921B1 (en)	2006-07-26
TW200302278A (en)	2003-08-01
ES2309909T3 (es)	2008-12-16
BR0306838A (pt)	2005-04-05
JP2005522191A (ja)	2005-07-28
WO2003062268A3 (en)	2003-11-27
DE60307044D1 (de)	2006-09-07
US20090124793A1 (en)	2009-05-14
JP4508648B2 (ja)	2010-07-21
CN100475844C (zh)	2009-04-08
RU2004124847A (ru)	2005-04-20
PL371364A1 (en)	2005-06-13
DE60321730D1 (de)	2008-07-31
KR20040082389A (ko)	2004-09-24
TWI300442B (en)	2008-09-01
JP4489434B2 (ja)	2010-06-23
PL373139A1 (en)	2005-08-22
EP1465922A2 (en)	2004-10-13
PE20030974A1 (es)	2003-12-26
NO20043366L (no)	2004-10-06
NZ533599A (en)	2007-03-30
KR100735586B1 (ko)	2007-07-04
CA2470656A1 (en)	2003-07-31
DK1465923T3 (da)	2007-07-02
US7192923B2 (en)	2007-03-20
PL373529A1 (en)	2005-09-05
ES2269976T3 (es)	2007-04-01
ATE383372T1 (de)	2008-01-15
TW200302277A (en)	2003-08-01
JP4508649B2 (ja)	2010-07-21
US20080004435A1 (en)	2008-01-03
US20030148958A1 (en)	2003-08-07
NZ533598A (en)	2007-03-30
CA2470731A1 (en)	2003-07-31
DE60318547T2 (de)	2008-12-24
DE60307044T2 (de)	2007-02-15

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