IL153594A0 - Amino alcohol derivatives and pharmaceutical compositions containing the same - Google Patents
Amino alcohol derivatives and pharmaceutical compositions containing the sameInfo
- Publication number
- IL153594A0 IL153594A0 IL15359401A IL15359401A IL153594A0 IL 153594 A0 IL153594 A0 IL 153594A0 IL 15359401 A IL15359401 A IL 15359401A IL 15359401 A IL15359401 A IL 15359401A IL 153594 A0 IL153594 A0 IL 153594A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- hydrogen atom
- same
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 150000001414 amino alcohols Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000006832 (C1-C10) alkylene group Chemical group 0.000 abstract 3
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000008629 immune suppression Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/32—Oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The present invention relates to compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives: <CHEM> wherein R<1> and R<2> are a hydrogen atom, an amino protecting group; R<3> is a hydrogen atom, a hydroxy protecting group; R<4> is a lower alkyl group; n is an integer from 1 to 6; X is an ethylene group; Y is a C1-C10 alkylene group, a C1-C10 alkylene group substituted with 1 to 3 substituents selected from substituent group a and b; R<5> is an aryl group; R<6> and R<7> are a hydrogen atom, a group selected from substituent group a; with the proviso when R<5> is a hydrogen atom, Y is not a single bond or a straight chain C1-C10 alkylene group.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000212246 | 2000-07-13 | ||
JP2000241744 | 2000-08-09 | ||
JP2000283218 | 2000-09-19 | ||
PCT/JP2001/005988 WO2002006268A1 (en) | 2000-07-13 | 2001-07-10 | Amino alcohol derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IL153594A0 true IL153594A0 (en) | 2003-07-06 |
Family
ID=27344040
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15359401A IL153594A0 (en) | 2000-07-13 | 2001-07-10 | Amino alcohol derivatives and pharmaceutical compositions containing the same |
IL153594A IL153594A (en) | 2000-07-13 | 2002-12-22 | Amino alcohol derivatives and pharmaceutical compositions containing the same |
IL174664A IL174664A0 (en) | 2000-07-13 | 2006-03-30 | Optically active amino alcohol derivatives and processes for the preparation thereof |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL153594A IL153594A (en) | 2000-07-13 | 2002-12-22 | Amino alcohol derivatives and pharmaceutical compositions containing the same |
IL174664A IL174664A0 (en) | 2000-07-13 | 2006-03-30 | Optically active amino alcohol derivatives and processes for the preparation thereof |
Country Status (20)
Country | Link |
---|---|
US (2) | US6723745B2 (en) |
EP (1) | EP1300405B1 (en) |
KR (1) | KR100812578B1 (en) |
CN (2) | CN1328387C (en) |
AT (1) | ATE360011T1 (en) |
AU (2) | AU2001269503B2 (en) |
BR (1) | BR0112484A (en) |
CA (1) | CA2415678A1 (en) |
CZ (1) | CZ200350A3 (en) |
DE (1) | DE60127961D1 (en) |
HK (1) | HK1051680A1 (en) |
HU (1) | HUP0301688A3 (en) |
IL (3) | IL153594A0 (en) |
MX (1) | MXPA03000397A (en) |
NO (1) | NO20030120L (en) |
NZ (2) | NZ533997A (en) |
PL (1) | PL359411A1 (en) |
SK (1) | SK152003A3 (en) |
TW (1) | TWI301833B (en) |
WO (1) | WO2002006268A1 (en) |
Families Citing this family (50)
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US8882847B2 (en) | 2001-05-25 | 2014-11-11 | Conformis, Inc. | Patient selectable knee joint arthroplasty devices |
CZ200350A3 (en) * | 2000-07-13 | 2003-05-14 | Sankyo Company Limited | Aminoalcohol derivatives |
WO2002029001A2 (en) | 2000-10-03 | 2002-04-11 | University Of Virginian Patent Foundation | Novel lysophosphatidic acid receptor agonists and antagonists |
WO2002064616A2 (en) | 2001-01-30 | 2002-08-22 | University Of Virgina Patent Foundation | Agonists and antagonists of sphingosine-1-phosphate receptors |
ATE314383T1 (en) * | 2001-03-26 | 2006-01-15 | Novartis Pharma Gmbh | 2-AMINO-PROPANOL DERIVATIVES |
DE60328161D1 (en) * | 2002-01-11 | 2009-08-13 | Daiichi Sankyo Co Ltd | AMINO ALCOHOL DERIVATIVE OR PHOSPHONIC ACID DERIVATIVE AND MEDICAL COMPOSITION CONTAINING THEREOF |
EP1478641A1 (en) * | 2002-01-24 | 2004-11-24 | Eli Lilly And Company | Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine |
SI1505959T1 (en) | 2002-05-16 | 2009-04-30 | Novartis Ag | Use of edg receptor binding agents in cancer |
SE0202280D0 (en) * | 2002-07-19 | 2002-07-19 | Astrazeneca Ab | Novel compounds |
SE0202279D0 (en) * | 2002-07-19 | 2002-07-19 | Astrazeneca Ab | Novel comppounds |
EP1548003A4 (en) | 2002-09-19 | 2006-06-07 | Kyorin Seiyaku Kk | Amino alcohol derivative, addition salt thereof, and immunosuppressant |
KR20080103117A (en) | 2002-09-24 | 2008-11-26 | 노파르티스 아게 | Sphingosine-1-phosphate receptor agonists in the treatment of demyelinating disorders |
US7452911B2 (en) | 2002-10-31 | 2008-11-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
EP3075356B1 (en) | 2002-11-07 | 2023-07-05 | ConforMIS, Inc. | Method of selecting a meniscal implant |
CA2707750A1 (en) | 2003-04-08 | 2004-10-21 | Novartis Ag | Solid pharmaceutical compositions comprising a s1p receptor agonist and a sugar alcohol |
WO2005005383A1 (en) * | 2003-07-11 | 2005-01-20 | Sankyo Company, Limited | Amino alcohol compound |
TW200505416A (en) * | 2003-08-12 | 2005-02-16 | Mitsubishi Pharma Corp | Bi-aryl compound having immunosuppressive activity |
GB0320638D0 (en) | 2003-09-03 | 2003-10-01 | Novartis Ag | Organic compounds |
GB0329498D0 (en) | 2003-12-19 | 2004-01-28 | Novartis Ag | Organic compounds |
DE102004004719A1 (en) * | 2004-01-29 | 2005-08-18 | Basf Ag | Process for the preparation of enantiomerically pure aminoalcohols |
TWI355934B (en) | 2004-02-24 | 2012-01-11 | Sankyo Co | Pharmaceutical composition for treatment or prophy |
US7521473B2 (en) | 2004-02-25 | 2009-04-21 | Wyeth | Inhibitors of protein tyrosine phosphatase 1B |
US20090163523A1 (en) * | 2004-05-03 | 2009-06-25 | Philip Lake | Combinations comprising a s1p receptor agonist and a jak3 kinase inhibitor |
EP1750722A4 (en) | 2004-05-06 | 2010-03-10 | Univ Virginia | Novel lysophosphatidic acid receptor selective antagonists |
CA2571710A1 (en) | 2004-06-24 | 2006-11-02 | Nicholas Valiante | Small molecule immunopotentiators and assays for their detection |
BRPI0513110A (en) * | 2004-07-16 | 2008-04-29 | Kyorin Seiyaku Kk | medicament comprising diaryl sulfide compound or diaryl ether compound having a 2-amine-1,3-propanediol structure having a peripherally circulating lymphocyte reducing activity, in combination with an immunosuppressive agent and / or an antiinflammatory agent and expression method for the prevention of side effect |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
CA2574664C (en) | 2004-07-30 | 2013-01-15 | Novartis Ag | Compound formulations of 2-amino-1,3-propanediol compounds |
US7119211B2 (en) * | 2004-09-23 | 2006-10-10 | Yamakawa Chemical Industry Co., Ltd. | Process for preparing optically active 3-(methylamino)-1-(2-thienyl) propan-1-ol and intermediates for preparation |
PL1806338T3 (en) * | 2004-10-12 | 2016-07-29 | Kyorin Seiyaku Kk | Process for producing 2-amino-2-[2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl[ethyl]-1,3-propanediol hydrochloride and hydrates thereof. and intermediates the production thereof |
WO2006058316A1 (en) | 2004-11-29 | 2006-06-01 | Novartis Ag | Dosage regimen of an s1p receptor agonist |
GB0504544D0 (en) | 2005-03-04 | 2005-04-13 | Novartis Ag | Organic compounds |
GB0519274D0 (en) | 2005-09-21 | 2005-11-02 | Arakis Ltd | The treatment of neurodegenerative diseases |
BRPI0617077A2 (en) * | 2005-10-07 | 2015-01-06 | Kyorin Seiyaku Kk | THERAPEUTIC AGENT FOR TREATMENT OF LIVER DISEASES CONTAINING 2-AMINE-1, 3-PROPANEDIOL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR TREATMENT OF LIVER DISEASES |
TWI389683B (en) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
BRPI0710878A2 (en) | 2006-04-11 | 2015-03-31 | Novartis Ag | Organic compounds and their uses |
GB0612721D0 (en) | 2006-06-27 | 2006-08-09 | Novartis Ag | Organic compounds |
TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
PL2058317T3 (en) * | 2006-08-08 | 2014-03-31 | Kyorin Seiyaku Kk | Aminophosphoric acid ester derivative and s1p receptor modulator containing the same as active ingredient |
US8273748B2 (en) | 2006-08-08 | 2012-09-25 | Kyorin Pharmaceutical Co., Ltd. | Amino alcohol derivative and immunosuppresive agent having same as an active ingredient |
US20100040678A1 (en) | 2006-09-26 | 2010-02-18 | Michael Ambuhl | Organic compounds |
TW200906389A (en) * | 2007-05-25 | 2009-02-16 | Daiichi Sankyo Co Ltd | Pharmaceutical composition comprising of therapeutic or prophylactic agents for hepatitis |
ES2864671T3 (en) | 2007-10-12 | 2021-10-14 | Novartis Ag | Compositions comprising sphingosine 1-phosphate (s1p) receptor modulators |
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DE2817494A1 (en) * | 1977-05-03 | 1978-11-09 | Continental Pharma | AMINO ALCOHOL DERIVATIVE |
US4638070A (en) * | 1978-12-21 | 1987-01-20 | Continental Pharma | Heterocyclic amino-alcohol derivatives |
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JPS60132934A (en) * | 1983-11-21 | 1985-07-16 | Nippon Shinyaku Co Ltd | Butanol derivative |
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CZ200350A3 (en) * | 2000-07-13 | 2003-05-14 | Sankyo Company Limited | Aminoalcohol derivatives |
JP2004507552A (en) * | 2000-08-31 | 2004-03-11 | メルク エンド カムパニー インコーポレーテッド | Phosphate derivatives as immunomodulators |
US20040058894A1 (en) * | 2002-01-18 | 2004-03-25 | Doherty George A. | Selective S1P1/Edg1 receptor agonists |
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2001
- 2001-07-10 CZ CZ200350A patent/CZ200350A3/en unknown
- 2001-07-10 WO PCT/JP2001/005988 patent/WO2002006268A1/en active IP Right Grant
- 2001-07-10 IL IL15359401A patent/IL153594A0/en active IP Right Grant
- 2001-07-10 MX MXPA03000397A patent/MXPA03000397A/en active IP Right Grant
- 2001-07-10 CN CNB2005100590917A patent/CN1328387C/en not_active Expired - Fee Related
- 2001-07-10 NZ NZ533997A patent/NZ533997A/en unknown
- 2001-07-10 KR KR1020037000413A patent/KR100812578B1/en not_active IP Right Cessation
- 2001-07-10 BR BR0112484-6A patent/BR0112484A/en not_active IP Right Cessation
- 2001-07-10 EP EP01947965A patent/EP1300405B1/en not_active Expired - Lifetime
- 2001-07-10 NZ NZ523554A patent/NZ523554A/en unknown
- 2001-07-10 CN CNB018153402A patent/CN1267429C/en not_active Expired - Fee Related
- 2001-07-10 DE DE60127961T patent/DE60127961D1/en not_active Expired - Lifetime
- 2001-07-10 PL PL01359411A patent/PL359411A1/en unknown
- 2001-07-10 AU AU2001269503A patent/AU2001269503B2/en not_active Ceased
- 2001-07-10 SK SK15-2003A patent/SK152003A3/en not_active Application Discontinuation
- 2001-07-10 CA CA002415678A patent/CA2415678A1/en not_active Abandoned
- 2001-07-10 HU HU0301688A patent/HUP0301688A3/en unknown
- 2001-07-10 AT AT01947965T patent/ATE360011T1/en not_active IP Right Cessation
- 2001-07-10 AU AU6950301A patent/AU6950301A/en active Pending
- 2001-07-12 TW TW090117073A patent/TWI301833B/en active
-
2002
- 2002-12-22 IL IL153594A patent/IL153594A/en not_active IP Right Cessation
-
2003
- 2003-01-07 US US10/337,702 patent/US6723745B2/en not_active Expired - Fee Related
- 2003-01-10 NO NO20030120A patent/NO20030120L/en not_active Application Discontinuation
- 2003-05-06 HK HK03103214A patent/HK1051680A1/en not_active IP Right Cessation
- 2003-11-20 US US10/718,858 patent/US6964976B2/en not_active Expired - Fee Related
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2006
- 2006-03-30 IL IL174664A patent/IL174664A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
NZ523554A (en) | 2004-12-24 |
PL359411A1 (en) | 2004-08-23 |
CN1267429C (en) | 2006-08-02 |
US6964976B2 (en) | 2005-11-15 |
EP1300405A4 (en) | 2004-04-21 |
CN1494540A (en) | 2004-05-05 |
IL174664A0 (en) | 2006-08-20 |
TWI301833B (en) | 2008-10-11 |
EP1300405B1 (en) | 2007-04-18 |
MXPA03000397A (en) | 2003-05-27 |
HUP0301688A3 (en) | 2006-05-29 |
EP1300405A1 (en) | 2003-04-09 |
AU6950301A (en) | 2002-01-30 |
CZ200350A3 (en) | 2003-05-14 |
KR20030047988A (en) | 2003-06-18 |
HUP0301688A2 (en) | 2003-09-29 |
AU2001269503B2 (en) | 2005-02-17 |
WO2002006268A1 (en) | 2002-01-24 |
CN1680563A (en) | 2005-10-12 |
US6723745B2 (en) | 2004-04-20 |
IL153594A (en) | 2008-04-13 |
SK152003A3 (en) | 2004-07-07 |
US20040132784A1 (en) | 2004-07-08 |
CN1328387C (en) | 2007-07-25 |
ATE360011T1 (en) | 2007-05-15 |
NO20030120D0 (en) | 2003-01-10 |
CA2415678A1 (en) | 2003-01-10 |
HK1051680A1 (en) | 2003-08-15 |
US20030236297A1 (en) | 2003-12-25 |
NZ533997A (en) | 2005-11-25 |
KR100812578B1 (en) | 2008-03-13 |
BR0112484A (en) | 2003-09-23 |
DE60127961D1 (en) | 2007-05-31 |
NO20030120L (en) | 2003-03-11 |
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