IL132991A - Substituted pyrazoles, pharmaceutical compositionscomprising them and their use as p38 inase inhibi tors - Google Patents
Substituted pyrazoles, pharmaceutical compositionscomprising them and their use as p38 inase inhibi torsInfo
- Publication number
- IL132991A IL132991A IL13299198A IL13299198A IL132991A IL 132991 A IL132991 A IL 132991A IL 13299198 A IL13299198 A IL 13299198A IL 13299198 A IL13299198 A IL 13299198A IL 132991 A IL132991 A IL 132991A
- Authority
- IL
- Israel
- Prior art keywords
- inase
- substituted pyrazoles
- inhibi tors
- compositionscomprising
- pharmaceutical
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4757097P | 1997-05-22 | 1997-05-22 | |
| PCT/US1998/010436 WO1998052940A1 (en) | 1997-05-22 | 1998-05-22 | SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL132991A0 IL132991A0 (en) | 2001-03-19 |
| IL132991A true IL132991A (en) | 2005-11-20 |
Family
ID=21949743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13299198A IL132991A (en) | 1997-05-22 | 1998-05-22 | Substituted pyrazoles, pharmaceutical compositionscomprising them and their use as p38 inase inhibi tors |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1000055A1 (en) |
| JP (1) | JP2002508754A (en) |
| KR (1) | KR20010012854A (en) |
| CN (1) | CN1264377A (en) |
| AP (1) | AP1246A (en) |
| AU (1) | AU754830C (en) |
| BG (1) | BG64313B1 (en) |
| BR (1) | BR9809147A (en) |
| CA (1) | CA2291115A1 (en) |
| EA (1) | EA003925B1 (en) |
| EE (1) | EE9900527A (en) |
| GE (1) | GEP20033053B (en) |
| HU (1) | HUP0001880A3 (en) |
| ID (1) | ID22982A (en) |
| IL (1) | IL132991A (en) |
| IS (1) | IS5257A (en) |
| NO (1) | NO995695L (en) |
| NZ (1) | NZ501112A (en) |
| OA (1) | OA12981A (en) |
| PL (1) | PL337020A1 (en) |
| SK (1) | SK157899A3 (en) |
| TR (1) | TR200000235T2 (en) |
| WO (1) | WO1998052940A1 (en) |
| ZA (1) | ZA984358B (en) |
Families Citing this family (77)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW289752B (en) * | 1994-03-11 | 1996-11-01 | Ciba Geigy Ag | |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| US6514977B1 (en) | 1997-05-22 | 2003-02-04 | G.D. Searle & Company | Substituted pyrazoles as p38 kinase inhibitors |
| WO1998052941A1 (en) | 1997-05-22 | 1998-11-26 | G.D. Searle And Co. | PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS |
| US6979686B1 (en) | 2001-12-07 | 2005-12-27 | Pharmacia Corporation | Substituted pyrazoles as p38 kinase inhibitors |
| EP1023066A4 (en) | 1997-06-13 | 2001-05-23 | Smithkline Beecham Corp | Novel pyrazole and pyrazoline substituted compounds |
| US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
| US6184226B1 (en) | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| US6649617B1 (en) | 1998-10-07 | 2003-11-18 | Smithkline Beecham Corporation | Treatment for stroke management |
| EP1140916B1 (en) | 1998-12-16 | 2002-11-13 | Aventis Pharma Limited | Heteroaryl-cyclic acetals |
| US6191147B1 (en) | 1998-12-24 | 2001-02-20 | Ppd Discovery, Inc. | Pyrazole compounds and uses thereof |
| EP1142890B1 (en) * | 1998-12-25 | 2005-08-03 | Teikoku Hormone Mfg. Co., Ltd. | Aminopyrazole derivatives |
| CZ20013435A3 (en) | 1999-03-26 | 2002-04-17 | Euro-Celtique S. A. | Aryl substituted pyrazoles, imidazoles, oxazoles, thiazoles and pyrroles as well as use thereof |
| ATE296820T1 (en) | 1999-06-03 | 2005-06-15 | Teikoku Hormone Mfg Co Ltd | SUBSTITUTED PYRAZOLE DERIVATIVES |
| US7122666B2 (en) | 1999-07-21 | 2006-10-17 | Sankyo Company, Limited | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses |
| AR032130A1 (en) * | 1999-08-13 | 2003-10-29 | Vertex Pharma | AN INHIBITOR COMPOUND OF PROTEIN KINASES, A PHARMACEUTICAL COMPOSITION THAT INCLUDES IT, AND A METHOD TO TREAT AFFECTIONS WITH SUCH COMPOUND |
| WO2001030154A2 (en) * | 1999-10-25 | 2001-05-03 | Basf Aktiengesellschaft | Agrochemical compositions containing pyrazoles and use thereof as fungicidal plant protection agents |
| DE19952147A1 (en) | 1999-10-29 | 2001-05-03 | Boehringer Ingelheim Pharma | New cyclopropanes, pharmaceutical compositions containing these compounds and process for their preparation |
| US7053099B1 (en) | 1999-11-23 | 2006-05-30 | Smithkline Beecham Corporation | 3,4-dihydro-(1H)quinazolin-2-one compounds as CSBP/p38 kinase inhibitors |
| CA2419550A1 (en) | 2000-08-14 | 2002-02-21 | Ortho-Mcneil Pharmaceutical, Inc. | Substituted pyrazoles |
| GB0102687D0 (en) | 2001-02-02 | 2001-03-21 | Pharmacia & Upjohn Spa | Oxazolyl-pyrazole derivatives active as kinase inhibitors,process for their preparation and pharmaceutical compositions comprising them |
| WO2002062792A1 (en) * | 2001-02-02 | 2002-08-15 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| EP2048142A3 (en) | 2001-04-26 | 2009-04-22 | Eisai R&D Management Co., Ltd. | Nitrogen-containing condensed cyclic compound having a pyrazolyl group as a substituent group and pharmaceutical composition thereof |
| UA76461C2 (en) | 2001-05-24 | 2006-08-15 | Lilly Co Eli | Pyrrazole derivatives as pharmaceutical agents, use thereof, a pharmaceutical composition on their basis |
| BR0212812A (en) | 2001-09-25 | 2004-08-03 | Pharmacia Corp | Processes for the manufacture of substituted pyrazoles and pharmaceutical composition comprising the same |
| US7057049B2 (en) | 2001-09-25 | 2006-06-06 | Pharmacia Corporation | Process for making substituted pyrazoles |
| US20040082551A1 (en) * | 2002-06-05 | 2004-04-29 | Benson Alan G. | Novel pyrazoles and their use as p38 kinase inhibitors |
| GB0215844D0 (en) | 2002-07-09 | 2002-08-14 | Novartis Ag | Organic compounds |
| CA2492033A1 (en) | 2002-07-09 | 2004-01-15 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases |
| GB0217786D0 (en) * | 2002-07-31 | 2002-09-11 | Glaxo Group Ltd | Compounds |
| WO2004016592A1 (en) | 2002-08-14 | 2004-02-26 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
| US6649638B1 (en) | 2002-08-14 | 2003-11-18 | Ppd Discovery, Inc. | Prenylation inhibitors and methods of their synthesis and use |
| WO2004026302A1 (en) * | 2002-09-19 | 2004-04-01 | Eli Lilly And Company | Methods of inhibiting tgf beta with substituted pyrazoles |
| GB0229618D0 (en) | 2002-12-19 | 2003-01-22 | Cancer Rec Tech Ltd | Pyrazole compounds |
| CA2515119A1 (en) | 2003-02-07 | 2004-08-19 | Daiichi Pharmaceutical Co., Ltd. | Pyrazole derivative |
| US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
| EP1778686B9 (en) | 2004-08-12 | 2009-07-08 | Pfizer Limited | Triazolopyridinylsulfanyl derivatives as p38 map kinase inhibitors |
| PE20060777A1 (en) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | INDOLINONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES |
| EP1832584B1 (en) | 2004-12-28 | 2011-12-21 | ASKA Pharmaceutical Co., Ltd. | Pyrimidinylisoxazole derivative |
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| KR20090031721A (en) * | 2006-06-28 | 2009-03-27 | 아스카 세이야쿠 가부시키가이샤 | Treatment agent for inflammatory bowel disease |
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| CA2731146C (en) | 2008-07-24 | 2016-05-03 | Nerviano Medical Sciences S.R.L. | 3,4-diarylpyrazoles as protein kinase inhibitors |
| EP2318403B1 (en) * | 2008-08-25 | 2015-12-23 | Boehringer Ingelheim International GmbH | Aryl- and heteroarylcarbonyl derivatives of substituted nortropanes, medicaments containing such compounds and their use |
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| CN108542906A (en) | 2011-11-11 | 2018-09-18 | 诺华股份有限公司 | The method for treating proliferative disease |
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| JP6579623B2 (en) | 2013-03-15 | 2019-09-25 | ザ・スクリップス・リサーチ・インスティテュート | Compounds and methods for inducing cartilage formation |
| BR112016012482B1 (en) * | 2013-12-12 | 2020-07-21 | Sumitomo Chemical Company, Limited | aromatic compound, its use, agent and method of pest control |
| CN104829536B (en) * | 2015-05-04 | 2017-12-29 | 陕西科技大学 | A kind of Phenylpyrazole carboxylic acid compound and its synthetic method for having antitumor activity |
| WO2016189877A1 (en) * | 2015-05-27 | 2016-12-01 | Kyorin Pharmaceutical Co., Ltd. | Urea derivative or pharmacologically acceptable salt thereof |
| CN109748873B (en) * | 2017-11-08 | 2021-02-02 | 北京嘉林药业股份有限公司 | Compounds and their use for treating cancer |
| CA3121202A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
| EP4085056A1 (en) | 2020-01-03 | 2022-11-09 | Berg LLC | Polycyclic amides as ube2k modulators for treating cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2753659B2 (en) * | 1990-09-03 | 1998-05-20 | 株式会社大塚製薬工場 | Pyrazole derivatives |
| US5593992A (en) * | 1993-07-16 | 1997-01-14 | Smithkline Beecham Corporation | Compounds |
| US5559137A (en) * | 1994-05-16 | 1996-09-24 | Smithkline Beecham Corp. | Compounds |
| US5486534A (en) * | 1994-07-21 | 1996-01-23 | G. D. Searle & Co. | 3,4-substituted pyrazoles for the treatment of inflammation |
| JP3734180B2 (en) * | 1994-12-28 | 2006-01-11 | エーザイ株式会社 | New pyrazole derivatives |
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1998
- 1998-05-22 AU AU75883/98A patent/AU754830C/en not_active Ceased
- 1998-05-22 AP APAP/P/1999/001715A patent/AP1246A/en active
- 1998-05-22 HU HU0001880A patent/HUP0001880A3/en unknown
- 1998-05-22 SK SK1578-99A patent/SK157899A3/en unknown
- 1998-05-22 ID IDW991425A patent/ID22982A/en unknown
- 1998-05-22 CN CN98807369A patent/CN1264377A/en active Pending
- 1998-05-22 NZ NZ501112A patent/NZ501112A/en unknown
- 1998-05-22 GE GEAP19985095A patent/GEP20033053B/en unknown
- 1998-05-22 BR BR9809147-6A patent/BR9809147A/en not_active Application Discontinuation
- 1998-05-22 EP EP98923642A patent/EP1000055A1/en not_active Withdrawn
- 1998-05-22 IL IL13299198A patent/IL132991A/en not_active IP Right Cessation
- 1998-05-22 WO PCT/US1998/010436 patent/WO1998052940A1/en not_active Application Discontinuation
- 1998-05-22 PL PL98337020A patent/PL337020A1/en unknown
- 1998-05-22 TR TR2000/00235T patent/TR200000235T2/en unknown
- 1998-05-22 CA CA002291115A patent/CA2291115A1/en not_active Abandoned
- 1998-05-22 EA EA199900953A patent/EA003925B1/en not_active IP Right Cessation
- 1998-05-22 EE EEP199900527A patent/EE9900527A/en unknown
- 1998-05-22 ZA ZA984358A patent/ZA984358B/en unknown
- 1998-05-22 KR KR19997010820A patent/KR20010012854A/en not_active Application Discontinuation
- 1998-05-22 JP JP55065098A patent/JP2002508754A/en not_active Withdrawn
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1999
- 1999-11-19 NO NO995695A patent/NO995695L/en not_active Application Discontinuation
- 1999-11-19 IS IS5257A patent/IS5257A/en unknown
- 1999-11-22 OA OA9900252A patent/OA12981A/en unknown
- 1999-12-08 BG BG103964A patent/BG64313B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002508754A (en) | 2002-03-19 |
| BG64313B1 (en) | 2004-09-30 |
| EA199900953A1 (en) | 2000-10-30 |
| AU754830B2 (en) | 2002-11-28 |
| ID22982A (en) | 1999-12-23 |
| BG103964A (en) | 2000-08-31 |
| EE9900527A (en) | 2000-06-15 |
| IL132991A0 (en) | 2001-03-19 |
| IS5257A (en) | 1999-11-19 |
| EP1000055A1 (en) | 2000-05-17 |
| NO995695D0 (en) | 1999-11-19 |
| CN1264377A (en) | 2000-08-23 |
| BR9809147A (en) | 2000-08-01 |
| GEP20033053B (en) | 2003-08-25 |
| HUP0001880A2 (en) | 2001-03-28 |
| SK157899A3 (en) | 2000-08-14 |
| AU7588398A (en) | 1998-12-11 |
| HUP0001880A3 (en) | 2002-03-28 |
| AP1246A (en) | 2004-02-07 |
| EA003925B1 (en) | 2003-10-30 |
| CA2291115A1 (en) | 1998-11-26 |
| NZ501112A (en) | 2002-10-25 |
| ZA984358B (en) | 1999-05-24 |
| OA12981A (en) | 2006-10-13 |
| TR200000235T2 (en) | 2000-05-22 |
| KR20010012854A (en) | 2001-02-26 |
| AU754830C (en) | 2004-02-12 |
| PL337020A1 (en) | 2000-07-31 |
| WO1998052940A1 (en) | 1998-11-26 |
| AP9901715A0 (en) | 1999-12-31 |
| NO995695L (en) | 2000-01-21 |
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