IL121407A0 - Substituted indanylidineacetylguanidines process for their preparation their use as medicaments or in diagnosis and medicaments containing them - Google Patents

Substituted indanylidineacetylguanidines process for their preparation their use as medicaments or in diagnosis and medicaments containing them

Info

Publication number
IL121407A0
IL121407A0 IL12140797A IL12140797A IL121407A0 IL 121407 A0 IL121407 A0 IL 121407A0 IL 12140797 A IL12140797 A IL 12140797A IL 12140797 A IL12140797 A IL 12140797A IL 121407 A0 IL121407 A0 IL 121407A0
Authority
IL
Israel
Prior art keywords
medicaments
indanylidineacetylguanidines
diagnosis
substituted
preparation
Prior art date
Application number
IL12140797A
Other languages
English (en)
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL121407A0 publication Critical patent/IL121407A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • C07C327/38—Amides of thiocarboxylic acids
    • C07C327/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
    • C07C327/54—Y being a hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL12140797A 1996-07-30 1997-07-28 Substituted indanylidineacetylguanidines process for their preparation their use as medicaments or in diagnosis and medicaments containing them IL121407A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96112275A EP0837055A1 (en) 1996-07-30 1996-07-30 Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them

Publications (1)

Publication Number Publication Date
IL121407A0 true IL121407A0 (en) 1998-01-04

Family

ID=8223055

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12140797A IL121407A0 (en) 1996-07-30 1997-07-28 Substituted indanylidineacetylguanidines process for their preparation their use as medicaments or in diagnosis and medicaments containing them

Country Status (29)

Country Link
US (1) US5900436A (xx)
EP (2) EP0837055A1 (xx)
JP (1) JP4039589B2 (xx)
KR (1) KR980009236A (xx)
CN (1) CN1064351C (xx)
AR (1) AR008095A1 (xx)
AT (1) ATE207888T1 (xx)
AU (1) AU715187B2 (xx)
BR (1) BR9704131A (xx)
CA (1) CA2211982C (xx)
CZ (1) CZ241197A3 (xx)
DE (1) DE69707777T2 (xx)
DK (1) DK0822182T3 (xx)
ES (1) ES2164283T3 (xx)
HR (1) HRP970424B1 (xx)
HU (1) HUP9701316A3 (xx)
ID (1) ID17565A (xx)
IL (1) IL121407A0 (xx)
MX (1) MX9705737A (xx)
NO (1) NO308213B1 (xx)
NZ (1) NZ328440A (xx)
PL (1) PL321392A1 (xx)
PT (1) PT822182E (xx)
RU (1) RU2176638C2 (xx)
SI (1) SI0822182T1 (xx)
SK (1) SK282128B6 (xx)
TR (1) TR199700704A2 (xx)
TW (1) TW445251B (xx)
ZA (1) ZA976735B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2384318T (pt) 2008-12-31 2018-02-07 Ardelyx Inc Compostos e métodos para inibir o antiporte mediado por nhe no tratamento de distúrbios associados com a retenção de fluidos ou sobrecarga de sal e distúrbios do trato gastrointestinal
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine
KR20210117282A (ko) 2013-04-12 2021-09-28 알데릭스, 인코포레이티드 Nhe3-결합 화합물 및 포스페이트 수송을 저해하는 방법
AU2018205400B2 (en) 2017-01-09 2022-07-14 Ardelyx, Inc. Compounds useful for treating gastrointestinal tract disorders
EP3565811A1 (en) 2017-01-09 2019-11-13 Ardelyx, Inc. Inhibitors of nhe-mediated antiport
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE4421536A1 (de) * 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
CN1172104A (zh) 1998-02-04
AU3155497A (en) 1998-02-05
HUP9701316A3 (en) 1998-07-28
NO308213B1 (no) 2000-08-14
PT822182E (pt) 2002-03-28
CA2211982C (en) 2007-09-18
KR980009236A (ko) 1998-04-30
ID17565A (id) 1998-01-08
SI0822182T1 (en) 2002-04-30
NO973486D0 (no) 1997-07-29
EP0837055A1 (en) 1998-04-22
ES2164283T3 (es) 2002-02-16
JPH1129545A (ja) 1999-02-02
US5900436A (en) 1999-05-04
JP4039589B2 (ja) 2008-01-30
TW445251B (en) 2001-07-11
CA2211982A1 (en) 1998-01-30
DE69707777D1 (de) 2001-12-06
CZ241197A3 (cs) 1998-02-18
HRP970424B1 (en) 2002-06-30
MX9705737A (es) 1998-02-28
CN1064351C (zh) 2001-04-11
EP0822182B1 (en) 2001-10-31
HUP9701316A2 (hu) 1998-03-02
RU2176638C2 (ru) 2001-12-10
TR199700704A2 (xx) 1998-02-21
NO973486L (no) 1998-02-02
DE69707777T2 (de) 2003-01-16
NZ328440A (en) 1997-11-24
BR9704131A (pt) 1998-12-29
AU715187B2 (en) 2000-01-20
DK0822182T3 (da) 2002-02-25
PL321392A1 (en) 1998-02-02
AR008095A1 (es) 1999-12-09
SK282128B6 (sk) 2001-11-06
HRP970424A2 (en) 1998-06-30
SK103497A3 (en) 1998-02-04
HU9701316D0 (en) 1997-09-29
ZA976735B (en) 1998-01-30
ATE207888T1 (de) 2001-11-15
EP0822182A1 (en) 1998-02-04

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