ID28005A - 4-benzil piperidina alkilsulfoksida heterolingkar dan penggunaannya sebagai antagonis subtipe reseptor nmda selektif - Google Patents

4-benzil piperidina alkilsulfoksida heterolingkar dan penggunaannya sebagai antagonis subtipe reseptor nmda selektif

Info

Publication number: ID28005A
Authority: ID; Indonesia
Prior art keywords: subtipe; heterolingcar; alkylsulfoxide; antagonists; nmda receptor
Prior art date: 1998-06-26

Application number

IDW20002514A

Other languages

English (en)

Inventor

Jonathan L Wright

Suzanne Ross Kesten

Ravindra B Upsani

Nancy C Lan

Original Assignee

Warner Lambert Company Cs

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-06-26

Filing date

1999-06-25

Publication date

2001-05-03

1999-06-25 Application filed by Warner Lambert Company Cs filed Critical Warner Lambert Company Cs

2001-05-03 Publication of ID28005A publication Critical patent/ID28005A/id

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Ophthalmology & Optometry (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IDW20002514A 1998-06-26 1999-06-25 4-benzil piperidina alkilsulfoksida heterolingkar dan penggunaannya sebagai antagonis subtipe reseptor nmda selektif ID28005A (id)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US9091498P	1998-06-26	1998-06-26

Publications (1)

Publication Number	Publication Date
ID28005A true ID28005A (id)	2001-05-03

Family

ID=22224939

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IDW20002514A ID28005A (id)	1998-06-26	1999-06-25	4-benzil piperidina alkilsulfoksida heterolingkar dan penggunaannya sebagai antagonis subtipe reseptor nmda selektif

Country Status (28)

Country	Link
US (1)	US6284774B1 (id)
EP (1)	EP1089735B1 (id)
JP (1)	JP2002519322A (id)
KR (1)	KR20010053170A (id)
CN (1)	CN1304307A (id)
AP (1)	AP2000001949A0 (id)
AT (1)	ATE297207T1 (id)
AU (1)	AU769650B2 (id)
BG (1)	BG105082A (id)
BR (1)	BR9911575A (id)
CA (1)	CA2327888A1 (id)
DE (1)	DE69925730T2 (id)
EA (1)	EA200100058A1 (id)
EE (1)	EE200000778A (id)
ES (1)	ES2244201T3 (id)
HU (1)	HUP0102471A2 (id)
ID (1)	ID28005A (id)
IL (1)	IL138949A0 (id)
IS (1)	IS5667A (id)
NO (1)	NO20006482L (id)
NZ (1)	NZ508808A (id)
OA (1)	OA11570A (id)
PE (1)	PE20000728A1 (id)
PL (1)	PL345024A1 (id)
SK (1)	SK19512000A3 (id)
TR (1)	TR200003888T2 (id)
WO (1)	WO2000000197A1 (id)
ZA (1)	ZA200005848B (id)

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KR100849839B1 (ko)	2001-02-23	2008-08-01	머크 앤드 캄파니 인코포레이티드	Ｎ-치환된 비-아릴-헤테로사이클릭 ｎｍｄａ/ｎｒ2ｂ 길항제 및 이를 포함하는 약제학적 조성물
EP1436258A4 (en) *	2001-03-08	2005-03-23	Univ Emory	ANTAGONISTS OF THE NMDA RECEPTOR DEPENDENT OF PH
EP1390034A4 (en)	2001-04-03	2005-07-13	Merck & Co Inc	NMDA / NR2B NONARYL-HETEROCYCLO AMIDYL N-SUBSTITUTE ANTAGONISTS
CA2381630A1 (en) *	2001-04-23	2002-10-23	Leonard Theodore Meltzer	Method for preventing dyskinesias
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AU2002324846B2 (en)	2001-08-31	2007-05-10	Childrens Hospital Medical Center	Phosphodiesterase activity and regulation of phosphodiesterase 1-B-mediated signaling in brain
KR20040066890A (ko) *	2001-12-11	2004-07-27	유니버시티 오브 버지니아 페이턴트 파운데이션	근위축성 측삭 경화증 치료를 위한 프라미펙솔의 용도
US20060281797A1 (en) *	2001-12-11	2006-12-14	University Of Virginia Patent Foundation	Neurorestoration with R(+) Pramipexole
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US7732162B2 (en)	2003-05-05	2010-06-08	Probiodrug Ag	Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases
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AU2005322611A1 (en) *	2004-12-23	2006-07-06	Voyager Pharmaceutical Corporation	Leuprolide acetate and acetylcholinesterase inhibitors or NMDA receptor antagonists for the treatment of Alzheimer's disease
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JP5379692B2 (ja)	2006-11-09	2013-12-25	プロビオドルグエージー	潰瘍、癌及び他の疾患の治療のためのグルタミニルシクラーゼの阻害薬としての３−ヒドロキシ−１，５−ジヒドロ−ピロール−２−オン誘導体
SI2091948T1 (sl)	2006-11-30	2012-07-31	Probiodrug Ag	Novi inhibitorji glutaminil ciklaze
US8524695B2 (en)	2006-12-14	2013-09-03	Knopp Neurosciences, Inc.	Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same
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BRPI0910575A2 (pt)	2008-04-18	2017-06-06	Arizona Board Of Regents A Body Corp Of The State Of Arizona Acting For And Behalf Of The Univ Of Ar	métodos para tratar degeneração macular relacionada com a idade, para limitar desenvolvimento de degeneração macular relacionada com a idade, e para identificar compostos para tratar degeneração macular relacionada com a idade, e, composição
CN102186350A (zh)	2008-08-19	2011-09-14	诺普神经科学股份有限公司	使用(r)-普拉克索的组合物与方法
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US8778970B2 (en)	2009-08-04	2014-07-15	Dainippon Sumitomo Pharma Co., Ltd	Benzyl piperidine compound
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US9662313B2 (en)	2013-02-28	2017-05-30	Knopp Biosciences Llc	Compositions and methods for treating amyotrophic lateral sclerosis in responders
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1999
- 1999-06-24 PE PE1999000567A patent/PE20000728A1/es not_active Application Discontinuation
- 1999-06-25 PL PL99345024A patent/PL345024A1/xx unknown
- 1999-06-25 AT AT99931887T patent/ATE297207T1/de not_active IP Right Cessation
- 1999-06-25 JP JP2000556782A patent/JP2002519322A/ja active Pending
- 1999-06-25 CA CA002327888A patent/CA2327888A1/en not_active Abandoned
- 1999-06-25 DE DE69925730T patent/DE69925730T2/de not_active Expired - Fee Related
- 1999-06-25 TR TR2000/03888T patent/TR200003888T2/xx unknown
- 1999-06-25 US US09/674,298 patent/US6284774B1/en not_active Expired - Fee Related
- 1999-06-25 ES ES99931887T patent/ES2244201T3/es not_active Expired - Lifetime
- 1999-06-25 AU AU48303/99A patent/AU769650B2/en not_active Ceased
- 1999-06-25 IL IL13894999A patent/IL138949A0/xx unknown
- 1999-06-25 KR KR1020007014745A patent/KR20010053170A/ko not_active Application Discontinuation
- 1999-06-25 BR BR9911575-1A patent/BR9911575A/pt not_active Application Discontinuation
- 1999-06-25 WO PCT/US1999/014291 patent/WO2000000197A1/en active IP Right Grant
- 1999-06-25 CN CN99807087A patent/CN1304307A/zh active Pending
- 1999-06-25 OA OA1200000347A patent/OA11570A/en unknown
- 1999-06-25 SK SK1951-2000A patent/SK19512000A3/sk unknown
- 1999-06-25 EE EEP200000778A patent/EE200000778A/xx unknown
- 1999-06-25 HU HU0102471A patent/HUP0102471A2/hu unknown
- 1999-06-25 EA EA200100058A patent/EA200100058A1/ru unknown
- 1999-06-25 NZ NZ508808A patent/NZ508808A/xx unknown
- 1999-06-25 AP APAP/P/2000/001949A patent/AP2000001949A0/en unknown
- 1999-06-25 ID IDW20002514A patent/ID28005A/id unknown
- 1999-06-25 EP EP99931887A patent/EP1089735B1/en not_active Expired - Lifetime
2000
- 2000-10-16 IS IS5667A patent/IS5667A/is unknown
- 2000-10-19 ZA ZA200005848A patent/ZA200005848B/en unknown
- 2000-12-19 NO NO20006482A patent/NO20006482L/no not_active Application Discontinuation
- 2000-12-21 BG BG105082A patent/BG105082A/xx unknown

Also Published As

Publication number	Publication date
BR9911575A (pt)	2001-03-20
AU4830399A (en)	2000-01-17
DE69925730D1 (de)	2005-07-14
HUP0102471A2 (hu)	2002-05-29
WO2000000197A1 (en)	2000-01-06
US6284774B1 (en)	2001-09-04
CN1304307A (zh)	2001-07-18
DE69925730T2 (de)	2006-03-23
SK19512000A3 (sk)	2001-08-06
TR200003888T2 (tr)	2001-06-21
NO20006482D0 (no)	2000-12-19
BG105082A (en)	2001-09-28
EE200000778A (et)	2002-04-15
AP2000001949A0 (en)	2000-12-31
AU769650B2 (en)	2004-01-29
EP1089735B1 (en)	2005-06-08
NZ508808A (en)	2002-12-20
IL138949A0 (en)	2001-11-25
EP1089735A4 (en)	2002-12-18
JP2002519322A (ja)	2002-07-02
PE20000728A1 (es)	2000-08-21
NO20006482L (no)	2000-12-19
ATE297207T1 (de)	2005-06-15
IS5667A (is)	2000-10-16
KR20010053170A (ko)	2001-06-25
EP1089735A1 (en)	2001-04-11
OA11570A (en)	2004-07-01
CA2327888A1 (en)	2000-01-06
PL345024A1 (en)	2001-11-19
EA200100058A1 (ru)	2001-08-27
ES2244201T3 (es)	2005-12-01
ZA200005848B (en)	2001-12-18

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