ID17938A - Penghambatan metalloproreinase-metalloproteinase oleh asam-asam 2-(w-aroilalkil)-4-biaril-4-oksobutirat - Google Patents
Penghambatan metalloproreinase-metalloproteinase oleh asam-asam 2-(w-aroilalkil)-4-biaril-4-oksobutiratInfo
- Publication number
- ID17938A ID17938A IDP971608A ID971608A ID17938A ID 17938 A ID17938 A ID 17938A ID P971608 A IDP971608 A ID P971608A ID 971608 A ID971608 A ID 971608A ID 17938 A ID17938 A ID 17938A
- Authority
- ID
- Indonesia
- Prior art keywords
- acid
- oxobobirate
- metalloproreinase
- biaril
- aroilalkil
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/80—Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/88—Unsaturated compounds containing keto groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64502996A | 1996-05-15 | 1996-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ID17938A true ID17938A (id) | 1998-02-12 |
Family
ID=24587374
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IDP971608A ID17938A (id) | 1996-05-15 | 1997-05-14 | Penghambatan metalloproreinase-metalloproteinase oleh asam-asam 2-(w-aroilalkil)-4-biaril-4-oksobutirat |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0904260B1 (id) |
JP (1) | JP3524556B2 (id) |
CN (1) | CN1119313C (id) |
AR (1) | AR007099A1 (id) |
AT (1) | ATE224350T1 (id) |
AU (1) | AU715877B2 (id) |
BR (1) | BR9709078A (id) |
CA (1) | CA2254750C (id) |
CO (1) | CO5011071A1 (id) |
DE (1) | DE69715619T2 (id) |
ES (1) | ES2184092T3 (id) |
HN (1) | HN1997000070A (id) |
HR (1) | HRP970242A2 (id) |
ID (1) | ID17938A (id) |
PA (1) | PA8429601A1 (id) |
PE (1) | PE66198A1 (id) |
SV (1) | SV1997000038A (id) |
TN (1) | TNSN97081A1 (id) |
TW (1) | TW457231B (id) |
WO (1) | WO1997043240A1 (id) |
YU (1) | YU18397A (id) |
ZA (1) | ZA974028B (id) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6288063B1 (en) | 1998-05-27 | 2001-09-11 | Bayer Corporation | Substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives as matrix metalloprotease inhibitors |
EP1031349A1 (en) * | 1999-02-25 | 2000-08-30 | Bayer Aktiengesellschaft | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases |
CA2944617A1 (en) | 2014-04-03 | 2015-10-08 | Bayer Pharma Aktiengesellschaft | Chiral 2,5-disubstituted cyclopentanecarboxylic acid derivatives and use thereof |
CA2944614A1 (en) | 2014-04-03 | 2015-10-08 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituted cyclopentane carboxylic acids for the treatment of respiratoy tract diseases |
US20170022171A1 (en) | 2014-04-03 | 2017-01-26 | Bayer Pharma Aktiengesellschaft | 2,5-disubstituted cyclopentanecarboxylic acids and their use |
CN116687925B (zh) * | 2022-11-04 | 2024-10-22 | 中国科学院遗传与发育生物学研究所 | 一种侵蚀性蛋白酶抑制剂及其应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS243570B1 (en) * | 1984-08-31 | 1986-06-12 | Miroslav Kuchar | Omega-aryloxoalkane acids |
GB9101468D0 (en) * | 1991-01-23 | 1991-03-06 | Ciba Geigy | Coating compositions |
US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
-
1997
- 1997-05-09 ZA ZA9704028A patent/ZA974028B/xx unknown
- 1997-05-09 HR HR08/645,029A patent/HRP970242A2/xx not_active Application Discontinuation
- 1997-05-09 TN TNTNSN97081A patent/TNSN97081A1/fr unknown
- 1997-05-09 CO CO97025187A patent/CO5011071A1/es unknown
- 1997-05-12 PA PA19978429601A patent/PA8429601A1/es unknown
- 1997-05-12 SV SV1997000038A patent/SV1997000038A/es not_active Application Discontinuation
- 1997-05-12 WO PCT/US1997/008608 patent/WO1997043240A1/en active IP Right Grant
- 1997-05-12 JP JP54119597A patent/JP3524556B2/ja not_active Expired - Fee Related
- 1997-05-12 TW TW086106287A patent/TW457231B/zh not_active IP Right Cessation
- 1997-05-12 BR BR9709078A patent/BR9709078A/pt not_active IP Right Cessation
- 1997-05-12 PE PE1997000364A patent/PE66198A1/es not_active Application Discontinuation
- 1997-05-12 HN HN1997000070A patent/HN1997000070A/es unknown
- 1997-05-12 AR ARP970101979A patent/AR007099A1/es unknown
- 1997-05-12 DE DE69715619T patent/DE69715619T2/de not_active Expired - Fee Related
- 1997-05-12 EP EP97924788A patent/EP0904260B1/en not_active Expired - Lifetime
- 1997-05-12 AU AU30104/97A patent/AU715877B2/en not_active Ceased
- 1997-05-12 YU YU18397A patent/YU18397A/sr unknown
- 1997-05-12 CA CA002254750A patent/CA2254750C/en not_active Expired - Fee Related
- 1997-05-12 AT AT97924788T patent/ATE224350T1/de not_active IP Right Cessation
- 1997-05-12 ES ES97924788T patent/ES2184092T3/es not_active Expired - Lifetime
- 1997-05-12 CN CN97196453A patent/CN1119313C/zh not_active Expired - Fee Related
- 1997-05-14 ID IDP971608A patent/ID17938A/id unknown
Also Published As
Publication number | Publication date |
---|---|
HRP970242A2 (en) | 1998-04-30 |
CO5011071A1 (es) | 2001-02-28 |
DE69715619D1 (de) | 2002-10-24 |
SV1997000038A (es) | 1998-09-01 |
JP2001509783A (ja) | 2001-07-24 |
PE66198A1 (es) | 1998-10-23 |
AU715877B2 (en) | 2000-02-10 |
PA8429601A1 (es) | 2000-05-24 |
TNSN97081A1 (fr) | 2005-03-15 |
AR007099A1 (es) | 1999-10-13 |
CN1234791A (zh) | 1999-11-10 |
WO1997043240A1 (en) | 1997-11-20 |
ES2184092T3 (es) | 2003-04-01 |
JP3524556B2 (ja) | 2004-05-10 |
EP0904260B1 (en) | 2002-09-18 |
CA2254750A1 (en) | 1997-11-20 |
ZA974028B (en) | 1998-02-19 |
CA2254750C (en) | 2003-09-30 |
ATE224350T1 (de) | 2002-10-15 |
EP0904260A1 (en) | 1999-03-31 |
DE69715619T2 (de) | 2003-01-16 |
AU3010497A (en) | 1997-12-05 |
TW457231B (en) | 2001-10-01 |
HN1997000070A (es) | 1997-09-08 |
BR9709078A (pt) | 1999-08-03 |
CN1119313C (zh) | 2003-08-27 |
YU18397A (en) | 1999-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ID17053A (id) | Derivat-derivat 2-(2-okso-etiliden)-imidazolidin-4-on | |
DE69918278D1 (de) | Substituierte indolalkansäure | |
ID19403A (id) | Senyawa-senyawa heterosiklik | |
ID16152A (id) | Senyawa-senyawa triaril | |
ID15904A (id) | Senyawa-senyawa tiofenopirimidina | |
EE200000321A (et) | Uudsed ühendid | |
DE69716924D1 (de) | Phosphonat-nukleotid-verbindungen | |
BR9708236A (pt) | Composto pró-fragrância | |
ID18685A (id) | Senyawa trisiklik tersubstitusi | |
ID23803A (id) | Turunan-turunan 2-(4-aril atau heteroaril-piperazin-1-ilmetil)-1h-indola | |
EE9800430A (et) | Uued ühendid | |
MA23779A1 (fr) | Compose 9-substitue 2-(2-n-alkoxyphenyl) - purine -6- ones | |
NO991561L (no) | 3-alkoksyisoksazol-4-yl-substituerte 2-aminokarboksylsyreforbindelser | |
DK0923594T3 (da) | Bromotiacumicinforbindelser | |
ID17938A (id) | Penghambatan metalloproreinase-metalloproteinase oleh asam-asam 2-(w-aroilalkil)-4-biaril-4-oksobutirat | |
DE69709659D1 (de) | Halopropargyl-einschlussverbindungen | |
EE9900012A (et) | Uudsed ühendid | |
NO994838D0 (no) | <pi>-kompleks-forbindelser | |
BR9707330A (pt) | Composição herbicida | |
SE9704542D0 (sv) | Novel pyridazinone compounds | |
SE9601599D0 (sv) | Novel compounds | |
IS4890A (is) | Ný pýridasín efnasambönd | |
SE9603470D0 (sv) | New compounds | |
SE9604787D0 (sv) | New compounds | |
SE9600555D0 (sv) | New compounds |