HUT55774A - Process for producing 13,14-dihydro-berbane derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing 13,14-dihydro-berbane derivatives and pharmaceutical compositions containing them

Info

Publication number
HUT55774A
HUT55774A HU447887A HU447887A HUT55774A HU T55774 A HUT55774 A HU T55774A HU 447887 A HU447887 A HU 447887A HU 447887 A HU447887 A HU 447887A HU T55774 A HUT55774 A HU T55774A
Authority
HU
Hungary
Prior art keywords
acid
ester
berbane
dihydro
derivatives
Prior art date
Application number
HU447887A
Other languages
Hungarian (hu)
Other versions
HU204048B (en
Inventor
Szilveszter Vizi
Csaba Szantay
Lajos Szabo
Istvan Toth
Istvan Hermecz
Jozsef Gaal
Laszlo Harsing
Gyoergy Somogyi
Tibor Szabo
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Mta Koezponti Kemiai Kutato In
Mta Kiserleti Orvostudomanyi K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet, Mta Koezponti Kemiai Kutato In, Mta Kiserleti Orvostudomanyi K filed Critical Chinoin Gyogyszer Es Vegyeszet
Priority to HU447887A priority Critical patent/HU204048B/en
Publication of HUT55774A publication Critical patent/HUT55774A/en
Publication of HU204048B publication Critical patent/HU204048B/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Novel racemic 13,14-di:de-hydro-berbine-derivs. and acid adduct salts of general formula (I) - where R1 and R2 represent together a methylene-di:oxy gp.; R3 = 1-4C linear- or branched-alkyl gp., are prepd. from a racemic 14-hydroxy cpd. of general formula (II), and from thionyl-chloride, phosphoryl-chloride in anhydrous pyridine, or di:methyl-formamide or from an acetic-acid-ester of cpd. (II) is boiled with anhydrous, acetic-anhydride or formic-acid-ester with formic acid, or sulphonic acid ester of (II) is boiled in an inert solvent. Prod. (I) is opt. converted to its acid adduct salts or the base is liberated from corresponding salts.
HU447887A 1987-10-06 1987-10-06 Process for producing 13,14-didehydroberban derivatives and pharmaceutical compositions same HU204048B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU447887A HU204048B (en) 1987-10-06 1987-10-06 Process for producing 13,14-didehydroberban derivatives and pharmaceutical compositions same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU447887A HU204048B (en) 1987-10-06 1987-10-06 Process for producing 13,14-didehydroberban derivatives and pharmaceutical compositions same

Publications (2)

Publication Number Publication Date
HUT55774A true HUT55774A (en) 1991-06-28
HU204048B HU204048B (en) 1991-11-28

Family

ID=10968076

Family Applications (1)

Application Number Title Priority Date Filing Date
HU447887A HU204048B (en) 1987-10-06 1987-10-06 Process for producing 13,14-didehydroberban derivatives and pharmaceutical compositions same

Country Status (1)

Country Link
HU (1) HU204048B (en)

Also Published As

Publication number Publication date
HU204048B (en) 1991-11-28

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Legal Events

Date Code Title Description
HPC4 Succession in title of patentee

Owner name: MTA KOEZPONTI KEMIAI KUTATO INTEZET, HU

Owner name: MTA KISERLETI ORVOSTUDOMANYI INTEZET, HU

HMM4 Cancellation of final prot. due to non-payment of fee
HNF4 Restoration of lapsed final prot.
HMM4 Cancellation of final prot. due to non-payment of fee
HNF9 Restoration of lapsed temporary prot.
HMM4 Cancellation of final prot. due to non-payment of fee