HUE053903T2 - Kombinációs terápia rák ellen - Google Patents
Kombinációs terápia rák ellenInfo
- Publication number
- HUE053903T2 HUE053903T2 HUE16718802A HUE16718802A HUE053903T2 HU E053903 T2 HUE053903 T2 HU E053903T2 HU E16718802 A HUE16718802 A HU E16718802A HU E16718802 A HUE16718802 A HU E16718802A HU E053903 T2 HUE053903 T2 HU E053903T2
- Authority
- HU
- Hungary
- Prior art keywords
- cancer
- combination therapy
- therapy
- combination
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6875—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin
- A61K47/6879—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin the immunoglobulin having two or more different antigen-binding sites, e.g. bispecific or multispecific immunoglobulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1084—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562146766P | 2015-04-13 | 2015-04-13 | |
| US201562190945P | 2015-07-10 | 2015-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE053903T2 true HUE053903T2 (hu) | 2021-07-28 |
Family
ID=55809223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE16718802A HUE053903T2 (hu) | 2015-04-13 | 2016-04-12 | Kombinációs terápia rák ellen |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US20180085472A1 (hu) |
| EP (2) | EP3964527A3 (hu) |
| JP (1) | JP6971850B2 (hu) |
| KR (1) | KR20170135924A (hu) |
| CN (2) | CN114681608A (hu) |
| AU (1) | AU2016249981B2 (hu) |
| BR (1) | BR112017020952A2 (hu) |
| CA (1) | CA2980460A1 (hu) |
| CY (1) | CY1123972T1 (hu) |
| DK (1) | DK3283527T3 (hu) |
| ES (1) | ES2857076T3 (hu) |
| HU (1) | HUE053903T2 (hu) |
| IL (1) | IL254705B (hu) |
| LT (1) | LT3283527T (hu) |
| MX (1) | MX2017013178A (hu) |
| PL (1) | PL3283527T3 (hu) |
| PT (1) | PT3283527T (hu) |
| RS (1) | RS61531B1 (hu) |
| SI (1) | SI3283527T1 (hu) |
| TW (1) | TWI725966B (hu) |
| WO (1) | WO2016168149A1 (hu) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108064176A (zh) | 2015-04-22 | 2018-05-22 | 库瑞瓦格股份公司 | 用于治疗肿瘤疾病的含有rna的组合物 |
| DK3294885T3 (da) | 2015-05-08 | 2020-08-10 | Curevac Real Estate Gmbh | Fremgangsmåde til at fremstille rna |
| JP6621252B2 (ja) * | 2015-06-17 | 2019-12-18 | 国立大学法人北海道大学 | 治療耐性がんに対する治療耐性低減剤 |
| SG11201810509PA (en) | 2016-06-20 | 2018-12-28 | Kymab Ltd | Anti-pd-l1 antibodies |
| WO2018144334A1 (en) * | 2017-02-02 | 2018-08-09 | Imclone Llc | Dosing regimen for anti-csf-1r antibody |
| MX2019010173A (es) | 2017-02-27 | 2019-11-21 | Shattuck Labs Inc | Proteínas quiméricas basadas en el csf1r. |
| CN110636861B (zh) * | 2017-03-03 | 2022-07-08 | 詹森生物科技公司 | 用于治疗癌症的包含小分子csf-1r抑制剂和特异性地结合cd40的激动性抗体的协同疗法 |
| WO2018183366A1 (en) * | 2017-03-28 | 2018-10-04 | Syndax Pharmaceuticals, Inc. | Combination therapies of csf-1r or csf-1 antibodies and a t-cell engaging therapy |
| EP3601353A1 (en) * | 2017-03-31 | 2020-02-05 | Five Prime Therapeutics, Inc. | Combination therapy for cancer using anti-gitr antibodies |
| WO2018195283A1 (en) * | 2017-04-19 | 2018-10-25 | Elstar Therapeutics, Inc. | Multispecific molecules and uses thereof |
| KR20200012920A (ko) | 2017-06-01 | 2020-02-05 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 항-cd40 항체, 이의 항원 결합 단편 및 이의 의학적 용도 |
| WO2019035938A1 (en) | 2017-08-16 | 2019-02-21 | Elstar Therapeutics, Inc. | MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF |
| CA3105448A1 (en) | 2018-07-03 | 2020-01-09 | Elstar Therapeutics, Inc. | Anti-tcr antibody molecules and uses thereof |
| TW202428604A (zh) * | 2018-07-09 | 2024-07-16 | 美商戊瑞治療有限公司 | 結合至ilt4的抗體 |
| JP2021534101A (ja) | 2018-08-09 | 2021-12-09 | ヴェルソー セラピューティクス， インコーポレイテッド | Ｃｃｒ２及びｃｓｆ１ｒを標的とするためのオリゴヌクレオチド組成物ならびにその使用 |
| EP3856350A1 (en) * | 2018-09-27 | 2021-08-04 | Marengo Therapeutics, Inc. | Csf1r/ccr2 multispecific antibodies |
| CN109364252B (zh) * | 2018-11-21 | 2021-09-28 | 南京大学 | 抑制ifn-i至arg1诱导通路在制备抗肿瘤药物组合物中的应用 |
| KR20210099027A (ko) * | 2018-11-30 | 2021-08-11 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | 항-cd40 항체, 이의 항원-결합 단편 및 약학적 용도 |
| EP3939998A4 (en) * | 2018-11-30 | 2022-08-10 | Jiangsu Hengrui Medicine Co., Ltd. | PHARMACEUTICAL COMPOSITION WITH CD40 ANTIBODY AND USE THEREOF |
| WO2020178313A1 (en) * | 2019-03-05 | 2020-09-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New biomarkers and biotargets in renal cell carcinoma |
| TW202103733A (zh) * | 2019-04-10 | 2021-02-01 | 南開大學 | 抗cd40抗體及其用途 |
| CN110904229B (zh) * | 2019-11-25 | 2020-09-29 | 济南市中心医院 | Ilt4在肿瘤诊治中的应用 |
| WO2021142573A1 (zh) * | 2020-01-13 | 2021-07-22 | 丁邦 | 一种融合蛋白及其制法和用途 |
| IL303266A (en) * | 2020-12-04 | 2023-07-01 | Univ Antwerpen | Combined immunotherapy of IL-15 and CD40 agonists in cancer treatment |
| CN112979749A (zh) * | 2021-02-26 | 2021-06-18 | 深圳海创生物科技有限公司 | 一种活性环肽、活性环肽组合物及其在制备具有抗氧化作用或抗衰老作用的产品中的应用 |
| AU2022255506A1 (en) | 2021-04-08 | 2023-11-09 | Marengo Therapeutics, Inc. | Multifunctional molecules binding to tcr and uses thereof |
| WO2024073111A2 (en) * | 2022-09-30 | 2024-04-04 | Adicet Therapeutics, Inc. | Affinity binding entities directed to b7h6 and methods of use thereof |
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2016
- 2016-04-12 HU HUE16718802A patent/HUE053903T2/hu unknown
- 2016-04-12 PL PL16718802T patent/PL3283527T3/pl unknown
- 2016-04-12 EP EP20212116.6A patent/EP3964527A3/en not_active Withdrawn
- 2016-04-12 CN CN202210198527.4A patent/CN114681608A/zh active Pending
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- 2016-04-12 CA CA2980460A patent/CA2980460A1/en active Pending
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- 2016-04-12 MX MX2017013178A patent/MX2017013178A/es unknown
- 2016-04-12 WO PCT/US2016/027038 patent/WO2016168149A1/en active Application Filing
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- 2016-04-12 LT LTEP16718802.8T patent/LT3283527T/lt unknown
- 2016-04-12 PT PT167188028T patent/PT3283527T/pt unknown
- 2016-04-12 SI SI201631091T patent/SI3283527T1/sl unknown
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2017
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2020
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| Publication number | Publication date |
|---|---|
| SI3283527T1 (sl) | 2021-04-30 |
| JP6971850B2 (ja) | 2021-11-24 |
| AU2016249981A1 (en) | 2017-10-12 |
| EP3964527A2 (en) | 2022-03-09 |
| JP2018512430A (ja) | 2018-05-17 |
| CN107709365A (zh) | 2018-02-16 |
| US20200237927A1 (en) | 2020-07-30 |
| EP3283527B1 (en) | 2021-01-13 |
| RS61531B1 (sr) | 2021-04-29 |
| DK3283527T3 (da) | 2021-03-08 |
| CN114681608A (zh) | 2022-07-01 |
| LT3283527T (lt) | 2021-03-25 |
| US20180085472A1 (en) | 2018-03-29 |
| CA2980460A1 (en) | 2016-10-20 |
| US11559583B2 (en) | 2023-01-24 |
| TWI725966B (zh) | 2021-05-01 |
| EP3283527A1 (en) | 2018-02-21 |
| BR112017020952A2 (pt) | 2018-07-10 |
| IL254705A0 (en) | 2017-11-30 |
| MX2017013178A (es) | 2018-03-01 |
| TW201702270A (zh) | 2017-01-16 |
| WO2016168149A1 (en) | 2016-10-20 |
| PL3283527T3 (pl) | 2021-06-14 |
| AU2016249981B2 (en) | 2022-02-17 |
| CY1123972T1 (el) | 2022-05-27 |
| IL254705B (en) | 2021-07-29 |
| EP3964527A3 (en) | 2022-06-15 |
| KR20170135924A (ko) | 2017-12-08 |
| PT3283527T (pt) | 2021-03-03 |
| ES2857076T3 (es) | 2021-09-28 |
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