HUE036224T2 - C1-gátló készítmények örökletes angioödéma megelõzésében és kezelésében történõ alkalmazásra - Google Patents

C1-gátló készítmények örökletes angioödéma megelõzésében és kezelésében történõ alkalmazásra

Info

Publication number
HUE036224T2
HUE036224T2 HUE14762343A HUE14762343A HUE036224T2 HU E036224 T2 HUE036224 T2 HU E036224T2 HU E14762343 A HUE14762343 A HU E14762343A HU E14762343 A HUE14762343 A HU E14762343A HU E036224 T2 HUE036224 T2 HU E036224T2
Authority
HU
Hungary
Prior art keywords
hae
prevention
treatment
hereditary angioedema
inh
Prior art date
Application number
HUE14762343A
Other languages
English (en)
Inventor
Cynthia Gallagher
Stephen Ruddy
Mark Manning
Original Assignee
Shire Viropharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51538486&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUE036224(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shire Viropharma Inc filed Critical Shire Viropharma Inc
Publication of HUE036224T2 publication Critical patent/HUE036224T2/hu

Links

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HUE14762343A 2013-03-15 2014-03-17 C1-gátló készítmények örökletes angioödéma megelõzésében és kezelésében történõ alkalmazásra HUE036224T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361791399P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
HUE036224T2 true HUE036224T2 (hu) 2018-06-28

Family

ID=51538486

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE17177676A HUE041837T2 (hu) 2013-03-15 2014-03-17 C1-INH készítmények és eljárások C1- észteráz inhibitor elégtelenséggel összefüggõ rendellenességek megelõzésére és kezelésére
HUE14762343A HUE036224T2 (hu) 2013-03-15 2014-03-17 C1-gátló készítmények örökletes angioödéma megelõzésében és kezelésében történõ alkalmazásra

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HUE17177676A HUE041837T2 (hu) 2013-03-15 2014-03-17 C1-INH készítmények és eljárások C1- észteráz inhibitor elégtelenséggel összefüggõ rendellenességek megelõzésére és kezelésére

Country Status (30)

Country Link
US (9) US9616111B2 (hu)
EP (3) EP3290046B1 (hu)
JP (9) JP6184581B2 (hu)
KR (4) KR102430453B1 (hu)
CN (2) CN105517559A (hu)
AU (3) AU2014232912A1 (hu)
BR (1) BR112015023207A8 (hu)
CA (2) CA3054718A1 (hu)
CY (2) CY1119419T1 (hu)
DE (1) DE202014011208U1 (hu)
DK (2) DK2968434T3 (hu)
EA (1) EA201591278A1 (hu)
ES (2) ES2639833T3 (hu)
GB (1) GB2530921B (hu)
HK (2) HK1220403A1 (hu)
HR (2) HRP20171269T1 (hu)
HU (2) HUE041837T2 (hu)
IL (2) IL241549B (hu)
LT (2) LT2968434T (hu)
ME (2) ME02865B (hu)
MX (3) MX2020004724A (hu)
NZ (2) NZ710730A (hu)
PL (2) PL3290046T3 (hu)
PT (2) PT2968434T (hu)
RS (2) RS58351B1 (hu)
SG (2) SG11201507616VA (hu)
SI (2) SI2968434T1 (hu)
TR (1) TR201900319T4 (hu)
WO (1) WO2014145519A2 (hu)
ZA (3) ZA201507604B (hu)

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US20170224788A1 (en) 2017-08-10
BR112015023207A8 (pt) 2018-01-23
JP2019073546A (ja) 2019-05-16
ZA201806793B (en) 2020-01-29
GB2530921B (en) 2017-09-20
AU2018229558B2 (en) 2020-03-05
PL2968434T3 (pl) 2018-01-31
AU2014232912A1 (en) 2015-09-03
US20180153972A1 (en) 2018-06-07
DK3290046T3 (en) 2019-03-18
US9616111B2 (en) 2017-04-11
MX2021011946A (es) 2021-11-17
ZA201507604B (en) 2018-05-30
JP6473534B2 (ja) 2019-02-20
JP2018119002A (ja) 2018-08-02
SG10201707598QA (en) 2017-10-30
AU2018229558A1 (en) 2018-10-04
AU2020203183A1 (en) 2020-06-04
JP2019073544A (ja) 2019-05-16
US20180110844A1 (en) 2018-04-26
US20160015795A1 (en) 2016-01-21
EP3508213A1 (en) 2019-07-10
IL276153B (en) 2022-06-01
LT2968434T (lt) 2017-09-25
JP6422520B2 (ja) 2018-11-14
ME03326B (me) 2019-10-20
US20190160158A1 (en) 2019-05-30
CA3054718A1 (en) 2014-09-18
IL241549B (en) 2020-08-31
JP2018119001A (ja) 2018-08-02
PT3290046T (pt) 2019-02-18
WO2014145519A3 (en) 2014-12-31
MX2015011281A (es) 2016-03-03
US11364288B2 (en) 2022-06-21
PL3290046T3 (pl) 2019-05-31
IL276153A (en) 2020-09-30
EP2968434B1 (en) 2017-06-28
NZ710730A (en) 2021-07-30
US10130690B2 (en) 2018-11-20
EP3290046A1 (en) 2018-03-07
CY1121653T1 (el) 2020-07-31
MX2020004724A (es) 2022-01-18
US11534482B2 (en) 2022-12-27
GB2530921A (en) 2016-04-06
JP2017105847A (ja) 2017-06-15
EA201591278A1 (ru) 2016-03-31
SI3290046T1 (sl) 2019-04-30
CA2904543C (en) 2019-10-08
DE202014011208U1 (de) 2018-08-23
JP2021088599A (ja) 2021-06-10
HRP20171269T1 (hr) 2017-11-03
JP6877472B2 (ja) 2021-05-26
KR20210129267A (ko) 2021-10-27
US20180085441A1 (en) 2018-03-29
ZA201706929B (en) 2019-05-29
SG11201507616VA (en) 2015-10-29
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CN105517559A (zh) 2016-04-20
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LT3290046T (lt) 2019-03-12
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JP2018119000A (ja) 2018-08-02
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CY1119419T1 (el) 2018-03-07
CA2904543A1 (en) 2014-09-18
AU2020203183B2 (en) 2022-06-02
HK1250912B (zh) 2020-01-10
US10080788B2 (en) 2018-09-25
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HUE041837T2 (hu) 2019-05-28
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KR20210021146A (ko) 2021-02-24
US20200261556A1 (en) 2020-08-20
PT2968434T (pt) 2017-09-18
SI2968434T1 (sl) 2017-11-30
ES2639833T3 (es) 2017-10-30
JP6877470B2 (ja) 2021-05-26
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ME02865B (me) 2018-04-20
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US10105423B2 (en) 2018-10-23
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JP6473536B2 (ja) 2019-02-20
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US10201595B2 (en) 2019-02-12
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HK1220403A1 (zh) 2017-05-05
BR112015023207A2 (pt) 2017-11-21

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