HRP20020349A2 - Tyrosine kinase inhibitors - Google Patents

Tyrosine kinase inhibitors Download PDF

Info

Publication number: HRP20020349A2
Authority: HR; Croatia
Prior art keywords: alkyl; indol; compound; cycloalkyl; alkynyl
Prior art date: 1999-10-19

Application number

HR20020349A

Other languages

English (en)

Croatian (hr)

Inventor

Kenneth L Arrington

Mark T Bilodeau

Mark E Fraley

George D Hartman

William F Hoffman

Randall W Hungate

Yuntae Kim

Original Assignee

Merck & Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-19

Filing date

2002-04-19

Publication date

2004-02-29

2002-04-19 Application filed by Merck & Co Inc filed Critical Merck & Co Inc

2004-02-29 Publication of HRP20020349A2 publication Critical patent/HRP20020349A2/hr

Links

229940121358 tyrosine kinase inhibitor Drugs 0.000 title claims description 6
239000005483 tyrosine kinase inhibitor Substances 0.000 title claims description 6
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-1 heterocylyl Chemical group 0.000 claims description 60
239000000203 mixture Substances 0.000 claims description 55
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125000001424 substituent group Chemical group 0.000 claims description 41
125000000753 cycloalkyl group Chemical group 0.000 claims description 40
125000000623 heterocyclic group Chemical group 0.000 claims description 40
125000000304 alkynyl group Chemical group 0.000 claims description 35
125000003342 alkenyl group Chemical group 0.000 claims description 32
102000004022 Protein-Tyrosine Kinases Human genes 0.000 claims description 31
108090000412 Protein-Tyrosine Kinases Proteins 0.000 claims description 31
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IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 19
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HR20020349A 1999-10-19 2002-04-19 Tyrosine kinase inhibitors HRP20020349A2 (en)

Applications Claiming Priority (2)

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US16035699P	1999-10-19	1999-10-19
PCT/US2000/028625 WO2001029025A2 (en)	1999-10-19	2000-10-16	Tyrosine kinase inhibitors

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JP (2)	JP3822494B2 (es)
KR (1)	KR100681724B1 (es)
CN (1)	CN1213045C (es)
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2000
- 2000-10-16 CA CA002387351A patent/CA2387351C/en not_active Expired - Fee Related
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- 2000-10-16 PL PL354292A patent/PL202842B1/pl not_active IP Right Cessation
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- 2000-10-16 DE DE60017179T patent/DE60017179T2/de not_active Expired - Lifetime
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2001
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2002
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2003
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Also Published As

Publication number	Publication date
IL148891A (en)	2008-12-29
MY137656A (en)	2009-02-27
SA01220048B1 (ar)	2007-01-23
DE60017179D1 (de)	2005-02-03
EG24381A (en)	2009-04-05
MXPA02003887A (es)	2002-09-30
EP1226136B1 (en)	2004-12-29
AR035626A1 (es)	2004-06-23
DZ3223A1 (fr)	2001-04-26
CO5261601A1 (es)	2003-03-31
BG65585B1 (bg)	2009-01-30
KR100681724B1 (ko)	2007-02-28
EE200200201A (et)	2003-06-16
BR0014843A (pt)	2002-06-11
NO20021820D0 (no)	2002-04-18
WO2001029025A3 (en)	2001-11-01
IS2165B (is)	2006-11-15
JP2006206609A (ja)	2006-08-10
CZ20021390A3 (cs)	2002-09-11
NZ518001A (en)	2004-05-28
HK1054931A1 (en)	2003-12-19
UA74560C2 (en)	2006-01-16
PE20010749A1 (es)	2001-07-16
JP2003512369A (ja)	2003-04-02
JP3822494B2 (ja)	2006-09-20
AU778588B2 (en)	2004-12-09
IL148891A0 (en)	2002-09-12
GEP20053530B (en)	2005-05-25
TWI239957B (en)	2005-09-21
SA06270148B1 (ar)	2007-01-23
ATE286045T1 (de)	2005-01-15
CN1213045C (zh)	2005-08-03
TR200201051T2 (tr)	2002-09-23
NO20021820L (no)	2002-05-23
PT1226136E (pt)	2005-04-29
EE05107B1 (et)	2008-12-15
IS6326A (is)	2002-03-27
ZA200202985B (en)	2003-06-25
HUP0203323A3 (en)	2004-01-28
HUP0203323A2 (hu)	2003-02-28
AU1571001A (en)	2001-04-30
EA005812B1 (ru)	2005-06-30
CN1409708A (zh)	2003-04-09
BG106710A (en)	2003-03-31
RS50380B (sr)	2009-11-10
YU28602A (sh)	2004-12-31
WO2001029025A2 (en)	2001-04-26
KR20020038959A (ko)	2002-05-24
NO325696B1 (no)	2008-07-07
EA200200473A1 (ru)	2002-10-31
EP1226136A2 (en)	2002-07-31
ES2234698T3 (es)	2005-07-01
CA2387351A1 (en)	2001-04-26
PL354292A1 (en)	2003-12-29
US6306874B1 (en)	2001-10-23
SK286628B6 (sk)	2009-02-05
SK6912002A3 (en)	2003-08-05
CA2387351C (en)	2009-09-08
PL202842B1 (pl)	2009-07-31
DE60017179T2 (de)	2006-01-05

Legal Events

Date	Code	Title	Description
2004-02-29	A1OB	Publication of a patent application
2004-08-31	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2008-10-16	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20081016 Year of fee payment: 9
2010-04-06	PNAN	Change of the applicant name, address/residence	Owner name: MERCK SHARP & DOHME CORP., US
2010-11-22	OBST	Application withdrawn

Publication	Publication Date	Title
EP1226136B1 (en)	2004-12-29	Tyrosine kinase inhibitors
US6794393B1 (en)	2004-09-21	Tyrosine kinase inhibitors
US6479512B1 (en)	2002-11-12	Tyrosine kinase inhibitors
US6958340B2 (en)	2005-10-25	Tyrosine kinase inhibitors
US6420382B2 (en)	2002-07-16	Tyrosine kinase inhibitors
US6927293B2 (en)	2005-08-09	Tyrosine kinase inhibitors
US7109204B2 (en)	2006-09-19	Tyrosine kinase inhibitors
US20040171630A1 (en)	2004-09-02	Tyrosine kinase inhibitors
US20010047007A1 (en)	2001-11-29	Tyrosine kinase inhibitors
US20040220216A1 (en)	2004-11-04	Tyrosine kinase inhibitors
AU3617900A (en)	2000-09-28	Tyrosine kinase inhibitors
JP2003523390A (ja)	2003-08-05	チロシンキナーゼ阻害薬
WO2003011838A1 (en)	2003-02-13	Tyrosine kinase inhibitors
US20040235826A1 (en)	2004-11-25	Tyrosine kinase ihnibitors