HK134494A - Substituted release azelastine containing medicaments - Google Patents

Substituted release azelastine containing medicaments

Info

Publication number
HK134494A
HK134494A HK134494A HK134494A HK134494A HK 134494 A HK134494 A HK 134494A HK 134494 A HK134494 A HK 134494A HK 134494 A HK134494 A HK 134494A HK 134494 A HK134494 A HK 134494A
Authority
HK
Hong Kong
Prior art keywords
azelastine
release
containing medicaments
substituted
substituted release
Prior art date
Application number
HK134494A
Inventor
Helmut Dr Hettche
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of HK134494A publication Critical patent/HK134494A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Rotary Pumps (AREA)
  • Switches With Compound Operations (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Azelastine-containing pharmaceutical compositions with controlled release of active substance using a release-delaying component, there being 0.001 to 800 parts of release-delaying component for one part by weight of azelastine (as base), and it also being possible for the azelastine to be in the form of its physiologically tolerated salts, and the rate of azelastine release being between 0.05 and 5 mg per hour.
HK134494A 1988-04-20 1994-12-01 Substituted release azelastine containing medicaments HK134494A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3813244 1988-04-20

Publications (1)

Publication Number Publication Date
HK134494A true HK134494A (en) 1994-12-09

Family

ID=6352451

Family Applications (1)

Application Number Title Priority Date Filing Date
HK134494A HK134494A (en) 1988-04-20 1994-12-01 Substituted release azelastine containing medicaments

Country Status (15)

Country Link
EP (1) EP0338444B1 (en)
JP (1) JP2950845B2 (en)
AT (1) ATE97572T1 (en)
AU (1) AU3318389A (en)
CA (1) CA1325976C (en)
DE (1) DE58906232D1 (en)
DK (1) DK172235B1 (en)
ES (1) ES2060685T3 (en)
FI (1) FI891865A (en)
HK (1) HK134494A (en)
HU (1) HU202403B (en)
IE (1) IE62778B1 (en)
MC (1) MC2025A1 (en)
PT (1) PT90308B (en)
ZA (1) ZA892877B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9003903D0 (en) * 1990-12-07 1990-12-07 Astra Ab NEW PHARMACEUTICAL FORMULATIONS
DE4207234A1 (en) * 1992-03-07 1993-09-09 Asta Medica Ag NEW AMINOCARBONIC ACID DERIVATIVES WITH ANTIALLERGIC / ANTIASTHMIC EFFECT AND METHOD FOR THE PRODUCTION THEREOF
JPH0710747A (en) * 1993-04-28 1995-01-13 Takeda Chem Ind Ltd Solid preparation and its production
GB9514842D0 (en) * 1995-07-20 1995-09-20 Smithkline Beecham Plc Novel formulation
JP4138910B2 (en) * 1997-07-02 2008-08-27 帝國製薬株式会社 Transdermal preparation containing azelastine hydrochloride with good transdermal absorbability and low skin irritation
UA67802C2 (en) * 1998-10-23 2004-07-15 Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А. CONTROLLED-RELEASE FORMULATIONS FOR ORAL ADMINISTRATION CONTAINING cGMP PDE-5 INHIBITOR (VARIANTS), METHOD FOR ITS PREPARATION AND METHOD FOR TREATING ERECTILE DYSFUNCTION
ID29852A (en) 1998-11-02 2001-10-18 Elan Corp Plc Cs COMPLEXION OF MULTI PARTICULATION MODIFICATION
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
CN1407884B (en) 1999-10-29 2012-06-20 欧罗赛铁克股份有限公司 Controlled release hydrocodone formulations
MXPA03003895A (en) 2000-10-30 2003-07-28 Euro Celtique Sa Controlled release hydrocodone formulations.
EP1396263A1 (en) * 2002-08-09 2004-03-10 Warner-Lambert Company Film coating for tablets and caplets
EP1585500B8 (en) * 2002-12-20 2017-07-26 Auritec Pharmaceuticals Coated particles for sustained-release pharmaceutical administration
HUE030388T2 (en) * 2004-11-24 2017-05-29 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods of use thereof
KR102069473B1 (en) 2013-03-21 2020-01-22 유프락시아 파마수티컬스 유에스에이 엘엘씨 Injectable sustained release composition and method of using the same for treating inflammation in joints and pain associated therewith
KR20180069055A (en) 2015-10-27 2018-06-22 유프락시아 파마수티컬스 인코포레이티드 Sustained release formulation of topical anesthetic

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3575135D1 (en) * 1984-09-14 1990-02-08 Asta Pharma Ag SUBSTITUTED BENZYLPHTHALAZINONE DERIVATIVES.

Also Published As

Publication number Publication date
ES2060685T3 (en) 1994-12-01
DE58906232D1 (en) 1994-01-05
JP2950845B2 (en) 1999-09-20
PT90308A (en) 1989-11-10
CA1325976C (en) 1994-01-11
HU202403B (en) 1991-03-28
DK189189A (en) 1989-10-21
ATE97572T1 (en) 1993-12-15
IE891263L (en) 1989-10-20
DK172235B1 (en) 1998-02-02
FI891865A (en) 1989-10-21
EP0338444B1 (en) 1993-11-24
HUT49808A (en) 1989-11-28
JPH01311024A (en) 1989-12-15
DK189189D0 (en) 1989-04-19
EP0338444A1 (en) 1989-10-25
MC2025A1 (en) 1990-04-25
ZA892877B (en) 1989-12-27
PT90308B (en) 1994-10-31
IE62778B1 (en) 1995-02-22
AU3318389A (en) 1989-10-26
FI891865A0 (en) 1989-04-19

Similar Documents

Publication Publication Date Title
PT615754E (en) SOLID FORMS OF CONTROLLED LIBERATION ORAL ADMINISTRATION FLUPERTINE
IL95691A0 (en) Thienylcarboxylates of amino alcohols,their preparation and pharmaceutical compositions containing them
EP0427247A3 (en) Pharmaceutical composition with r-alpha-lipoic acid or s-alpha-lipoic acid as the active ingredient
GR3007202T3 (en)
HK134494A (en) Substituted release azelastine containing medicaments
IL80149A (en) Pharmaceutical compositions containing toluidide derivatives against graft-versus-host diseases and autoimmune diseases
IL85523A (en) Stable alpha interferon complex,its preparation and pharmaceutical compositions comprising it
MY105121A (en) Pharmaceutical composition for systemic transdermal administration.
NZ218028A (en) Benzimidazole derivatives and pharmaceutical compositions
ZA928170B (en) Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid
ZA876731B (en) Therapeutic agents
DE3766200D1 (en) L-DOPA CONTAINING MEDICINAL PRODUCT.
PT86186A (en) Process for the preparation of benzimidazol derivatives and of pharmaceutical compositions containing the same
GR3006091T3 (en)
GR890100833A (en) Process for the preparation of a compound with gastric inhibitopy effect
DE3474774D1 (en) Therapeutic compositions for oral use containing stable s-adenosy1-l-methionine salts
GB2021409A (en) Pharmaceutical composition
GR3002765T3 (en) New pharmaceutical compositions for parenteral use containing a calcitonin as the active ingredient
HU9700842D0 (en) Pharmaceutical compositions based on stabilized lipophyl matrix giving controlled release for the active components
EP0380989A3 (en) Plaster for transdermal administration
EP0351876A3 (en) Composition for potentiating vaccination effect
ATE85218T1 (en) ORAL PHARMACEUTICAL FORM FOR THE TREATMENT OF HYPERTENSION WITH DILTIAZEM HYDROCHLORIDE ONCE DAILY.
GR3031360T3 (en) Composition based on ibuprofen, for oral usage
JO1519B1 (en) Novel compounds (Novel deravatives of Benzimidazoles active as anti-ulcer agents).
JO1531B1 (en) Novel pharmacological compounds

Legal Events

Date Code Title Description
PF Patent in force
CHPA Change of a particular in the register (except of change of ownership)
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080414