HK1257595A1 - 抑制胰島β細胞凋亡的藥物及其用途 - Google Patents

抑制胰島β細胞凋亡的藥物及其用途

Info

Publication number
HK1257595A1
HK1257595A1 HK18116714.1A HK18116714A HK1257595A1 HK 1257595 A1 HK1257595 A1 HK 1257595A1 HK 18116714 A HK18116714 A HK 18116714A HK 1257595 A1 HK1257595 A1 HK 1257595A1
Authority
HK
Hong Kong
Prior art keywords
drug
cell apoptosis
beta cell
pancreatic beta
inhibiting pancreatic
Prior art date
Application number
HK18116714.1A
Other languages
English (en)
Inventor
李季男
Original Assignee
深圳瑞健生命科學研究院有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳瑞健生命科學研究院有限公司 filed Critical 深圳瑞健生命科學研究院有限公司
Publication of HK1257595A1 publication Critical patent/HK1257595A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18116714.1A 2016-12-15 2018-12-28 抑制胰島β細胞凋亡的藥物及其用途 HK1257595A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611162269 2016-12-15

Publications (1)

Publication Number Publication Date
HK1257595A1 true HK1257595A1 (zh) 2019-10-25

Family

ID=62657342

Family Applications (6)

Application Number Title Priority Date Filing Date
HK18116713.2A HK1257594A1 (zh) 2016-12-15 2018-12-28 一種促進胰島β細胞損傷修復和減少胰島纖維化的方法
HK18116712.3A HK1257593A1 (zh) 2016-12-15 2018-12-28 治療糖尿病的新藥物及其用途
HK18116716.9A HK1257597A1 (zh) 2016-12-15 2018-12-28 一種使胰高血糖素、胰島素恢復正常平衡的方法
HK18116715.0A HK1257596A1 (zh) 2016-12-15 2018-12-28 一種促進胰島素分泌的方法
HK18116714.1A HK1257595A1 (zh) 2016-12-15 2018-12-28 抑制胰島β細胞凋亡的藥物及其用途
HK18116718.7A HK1257599A1 (zh) 2016-12-15 2018-12-28 一種促進胰島素受體底物-2表達的方法

Family Applications Before (4)

Application Number Title Priority Date Filing Date
HK18116713.2A HK1257594A1 (zh) 2016-12-15 2018-12-28 一種促進胰島β細胞損傷修復和減少胰島纖維化的方法
HK18116712.3A HK1257593A1 (zh) 2016-12-15 2018-12-28 治療糖尿病的新藥物及其用途
HK18116716.9A HK1257597A1 (zh) 2016-12-15 2018-12-28 一種使胰高血糖素、胰島素恢復正常平衡的方法
HK18116715.0A HK1257596A1 (zh) 2016-12-15 2018-12-28 一種促進胰島素分泌的方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18116718.7A HK1257599A1 (zh) 2016-12-15 2018-12-28 一種促進胰島素受體底物-2表達的方法

Country Status (2)

Country Link
CN (7) CN108210912A (zh)
HK (6) HK1257594A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111411072B (zh) * 2020-03-09 2022-10-11 同济大学 SLC30A8基因表达下调的抗糖尿病胰岛β细胞及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
AU2003210137A1 (en) * 2002-02-06 2003-09-02 N-Zyme Biotec Gmbh Method for producing recombinant proteins in micro-organisms
DK2914575T3 (da) * 2012-10-31 2021-01-18 Univ Michigan Regents Plasminogen-aktivator-1-inhibitorer og fremgangsmåder til anvendelse deraf

Also Published As

Publication number Publication date
CN108210903A (zh) 2018-06-29
HK1257593A1 (zh) 2019-10-25
HK1257597A1 (zh) 2019-10-25
CN108210912A (zh) 2018-06-29
HK1257596A1 (zh) 2019-10-25
HK1257594A1 (zh) 2019-10-25
CN108210911A (zh) 2018-06-29
CN108339114A (zh) 2018-07-31
CN108210913A (zh) 2018-06-29
HK1257599A1 (zh) 2019-10-25
CN108210901A (zh) 2018-06-29
CN108210907A (zh) 2018-06-29

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