HK1222658A1 - 氰基三唑化合物 - Google Patents

氰基三唑化合物

Info

Publication number
HK1222658A1
HK1222658A1 HK16110856.4A HK16110856A HK1222658A1 HK 1222658 A1 HK1222658 A1 HK 1222658A1 HK 16110856 A HK16110856 A HK 16110856A HK 1222658 A1 HK1222658 A1 HK 1222658A1
Authority
HK
Hong Kong
Prior art keywords
cyanotriazole
compounds
cyanotriazole compounds
Prior art date
Application number
HK16110856.4A
Other languages
English (en)
Inventor
Seiji Sato
Satoshi Matsuda
Chiharu Matsumura
Motohiro Itotani
Toshio Shinohara
Shigekazu Fujita
Yohji Sakurai
Kuninori Tai
Tae Fukushima
Naohide Kanemoto
Takashi Okamoto
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of HK1222658A1 publication Critical patent/HK1222658A1/zh

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    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4192—1,2,3-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
HK16110856.4A 2013-07-17 2016-09-14 氰基三唑化合物 HK1222658A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361847268P 2013-07-17 2013-07-17
US201361885254P 2013-10-01 2013-10-01
US201461928267P 2014-01-16 2014-01-16
PCT/JP2014/069501 WO2015008872A1 (en) 2013-07-17 2014-07-16 Cyanotriazole compounds

Publications (1)

Publication Number Publication Date
HK1222658A1 true HK1222658A1 (zh) 2017-07-07

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US (1) US10626095B2 (zh)
EP (2) EP4219477A1 (zh)
JP (1) JP6503336B2 (zh)
KR (1) KR102377635B1 (zh)
CN (1) CN105408325B (zh)
AU (1) AU2014291142B2 (zh)
CA (1) CA2917267C (zh)
EA (1) EA201690228A1 (zh)
HK (1) HK1222658A1 (zh)
IL (1) IL243592B (zh)
MX (1) MX2016000654A (zh)
MY (1) MY184572A (zh)
PH (1) PH12016500085B1 (zh)
SA (1) SA516370405B1 (zh)
SG (2) SG11201600108PA (zh)
TW (1) TWI641595B (zh)
WO (1) WO2015008872A1 (zh)
ZA (1) ZA201600353B (zh)

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WO2016130501A1 (en) * 2015-02-09 2016-08-18 Incyte Corporation Aza-heteroaryl compounds as pi3k-gamma inhibitors
CN107207459B (zh) * 2015-02-19 2021-03-30 捷恩智株式会社 具有苯并噻吩的液晶性化合物、液晶组合物及液晶显示元件
WO2017070089A1 (en) 2015-10-19 2017-04-27 Incyte Corporation Heterocyclic compounds as immunomodulators
TWI744256B (zh) 2015-11-06 2021-11-01 美商英塞特公司 作為ＰＩ３Ｋ-γ抑制劑之雜環化合物
SI3377488T1 (sl) 2015-11-19 2022-11-30 Incyte Corporation Heterociklične spojine kot imunomodulatorji
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CN106008474A (zh) * 2016-04-23 2016-10-12 上海大学 N2选择性烯醇醚取代的三氮唑衍生物及其制备方法
WO2017192961A1 (en) 2016-05-06 2017-11-09 Incyte Corporation Heterocyclic compounds as immunomodulators
WO2017205464A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
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US10138248B2 (en) 2016-06-24 2018-11-27 Incyte Corporation Substituted imidazo[2,1-f][1,2,4]triazines, substituted imidazo[1,2-a]pyridines, substituted imidazo[1,2-b]pyridazines and substituted imidazo[1,2-a]pyrazines as PI3K-γ inhibitors
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