HK1018443A1 - Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase - Google Patents

Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase

Info

Publication number
HK1018443A1
HK1018443A1 HK99103415A HK99103415A HK1018443A1 HK 1018443 A1 HK1018443 A1 HK 1018443A1 HK 99103415 A HK99103415 A HK 99103415A HK 99103415 A HK99103415 A HK 99103415A HK 1018443 A1 HK1018443 A1 HK 1018443A1
Authority
HK
Hong Kong
Prior art keywords
protein transferase
inhibition
farnesyl protein
derivatives useful
substituted
Prior art date
Application number
HK99103415A
Other languages
English (en)
Inventor
Arthur G Taveras
F George Njoroge
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of HK1018443A1 publication Critical patent/HK1018443A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
  • Confectionery (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
HK99103415A 1996-09-13 1999-08-07 Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase HK1018443A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71192596A 1996-09-13 1996-09-13
PCT/US1997/015905 WO1998011099A1 (en) 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase

Publications (1)

Publication Number Publication Date
HK1018443A1 true HK1018443A1 (en) 1999-12-24

Family

ID=24860067

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99103415A HK1018443A1 (en) 1996-09-13 1999-08-07 Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase

Country Status (21)

Country Link
EP (1) EP0931079B1 (xx)
JP (1) JP2001500508A (xx)
KR (1) KR20000036103A (xx)
CN (1) CN1122031C (xx)
AT (1) ATE209201T1 (xx)
AU (1) AU4337797A (xx)
BR (1) BR9711477A (xx)
CA (1) CA2264513C (xx)
CZ (1) CZ87499A3 (xx)
DE (1) DE69709774T2 (xx)
ES (1) ES2163195T3 (xx)
HK (1) HK1018443A1 (xx)
HU (1) HUP9904056A3 (xx)
ID (1) ID22156A (xx)
IL (1) IL128929A0 (xx)
NO (1) NO991229L (xx)
NZ (1) NZ334437A (xx)
PL (1) PL332253A1 (xx)
SK (1) SK33599A3 (xx)
TR (1) TR199901205T2 (xx)
WO (1) WO1998011099A1 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002506444A (ja) * 1997-06-17 2002-02-26 シェーリング コーポレイション ファルネシルタンパク質トランスフェラーゼの新規n置換尿素インヒビター
US6358968B1 (en) 1997-06-17 2002-03-19 Schering Corporation N-substituted urea inhibitors of farnesyl-protein transferase
CA2318088A1 (en) 1998-01-21 1999-07-29 Yoshisuke Nakasato Chemokine receptor antagonists and methods of use therefor
US6509346B2 (en) 1998-01-21 2003-01-21 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6613905B1 (en) 1998-01-21 2003-09-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
ID26618A (id) 1998-01-21 2001-01-25 Millennium Pharm Inc Antagonis-antagonis reseptor kemokin dan metode penggunaannya
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6503926B2 (en) 1998-09-04 2003-01-07 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US7271176B2 (en) 1998-09-04 2007-09-18 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use thereof
US7541365B2 (en) 2001-11-21 2009-06-02 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) 2002-11-13 2007-12-21 Millennium Pharm Inc CCR1 antagonists and methods of use therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
US5719148A (en) * 1993-10-15 1998-02-17 Schering Corporation Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
EP1019392B1 (en) * 1995-12-22 2005-11-09 Schering Corporation Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases

Also Published As

Publication number Publication date
CA2264513C (en) 2004-03-30
KR20000036103A (ko) 2000-06-26
ES2163195T3 (es) 2002-01-16
DE69709774D1 (de) 2002-02-21
DE69709774T2 (de) 2002-08-08
CZ87499A3 (cs) 1999-08-11
SK33599A3 (en) 2000-03-13
WO1998011099A1 (en) 1998-03-19
TR199901205T2 (xx) 1999-07-21
HUP9904056A3 (en) 2001-10-29
JP2001500508A (ja) 2001-01-16
CN1122031C (zh) 2003-09-24
ATE209201T1 (de) 2001-12-15
IL128929A0 (en) 2000-02-17
CA2264513A1 (en) 1998-03-19
NO991229L (no) 1999-05-12
EP0931079A1 (en) 1999-07-28
CN1236364A (zh) 1999-11-24
AU4337797A (en) 1998-04-02
NZ334437A (en) 2000-09-29
NO991229D0 (no) 1999-03-12
PL332253A1 (en) 1999-08-30
HUP9904056A2 (hu) 2000-04-28
BR9711477A (pt) 1999-08-24
ID22156A (id) 1999-09-09
EP0931079B1 (en) 2001-11-21

Similar Documents

Publication Publication Date Title
IL128928A0 (en) Tricyclic inhibitors of farnesyl protein transferase
HK1018446A1 (en) Tricyclic antitumor compounds being farnesyl protein transferase inhibitors.
HK1018443A1 (en) Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase
NO991235D0 (no) Forbindelser anvendelige for inhibering av farnesylproteintransferase
IL128927A0 (en) Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase
IL128930A0 (en) Compounds useful for inhibition of farnesyl protein transferase

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20050911