GR79158B - - Google Patents
Info
- Publication number
- GR79158B GR79158B GR73477A GR840173477A GR79158B GR 79158 B GR79158 B GR 79158B GR 73477 A GR73477 A GR 73477A GR 840173477 A GR840173477 A GR 840173477A GR 79158 B GR79158 B GR 79158B
- Authority
- GR
- Greece
- Prior art keywords
- alkyl
- denotes
- aryl
- denotes hydrogen
- alkenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/96—Spiro-condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19833300774 DE3300774A1 (de) | 1983-01-12 | 1983-01-12 | Neue spirocyclische aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue spirocyclische aminosaeuren als zwischenprodukte und verfahren zu deren herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR79158B true GR79158B (el) | 1984-10-02 |
Family
ID=6188100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR73477A GR79158B (el) | 1983-01-12 | 1984-01-10 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4620012A (el) |
| EP (1) | EP0116276B1 (el) |
| JP (1) | JPH0759590B2 (el) |
| KR (1) | KR910003185B1 (el) |
| AT (1) | ATE39931T1 (el) |
| AU (1) | AU575308B2 (el) |
| DE (2) | DE3300774A1 (el) |
| DK (1) | DK166586C (el) |
| ES (2) | ES8406880A1 (el) |
| GR (1) | GR79158B (el) |
| IE (1) | IE56544B1 (el) |
| PT (1) | PT77943B (el) |
| ZA (1) | ZA84213B (el) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3226768A1 (de) * | 1981-11-05 | 1983-05-26 | Hoechst Ag, 6230 Frankfurt | Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
| GR78413B (el) * | 1981-12-29 | 1984-09-27 | Hoechst Ag | |
| US5175306A (en) * | 1983-01-31 | 1992-12-29 | Hoechst Aktiengesellschaft | Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters |
| DE3333455A1 (de) * | 1983-09-16 | 1985-04-11 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung n-alkylierter dipeptide und deren estern |
| DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
| US5684016A (en) * | 1984-04-12 | 1997-11-04 | Hoechst Aktiengesellschaft | Method of treating cardiac insufficiency |
| DE3431541A1 (de) * | 1984-08-28 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung |
| WO1986007064A1 (en) * | 1985-05-22 | 1986-12-04 | Takeda Chemical Industries, Ltd. | Piperidine derivatives |
| US5231080A (en) * | 1985-10-15 | 1993-07-27 | Hoechst Aktiengesellschaft | Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease |
| US5231084A (en) * | 1986-03-27 | 1993-07-27 | Hoechst Aktiengesellschaft | Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons |
| DE3610391A1 (de) * | 1986-03-27 | 1987-10-08 | Hoechst Ag | Verbindungen mit nootroper wirkung, diese enthaltende mittel und deren verwendung bei der behandlung und prophylaxe cognitiver dysfunktionen |
| CS277405B6 (en) * | 1986-06-12 | 1993-03-17 | Vyzk Ustav Farm Biochem Sp | Peptides with 1-amino-1-cycloalkane carboxylic acid |
| DE3633496A1 (de) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln |
| DE3639879A1 (de) * | 1986-11-21 | 1988-06-01 | Hoechst Ag | Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung |
| DE3722007A1 (de) * | 1987-07-03 | 1989-01-12 | Hoechst Ag | Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung |
| HU904967D0 (en) * | 1988-04-22 | 1991-01-28 | Hoechst Ag | Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives |
| KR20010033158A (ko) * | 1997-12-16 | 2001-04-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 1-치환-1-아미노메틸-시클로알칸 유도체 (=가바펜틴동족체), 그의 제조법 및 신경성 질환 치료에 있어서 그의용도 |
| MXPA05011168A (es) * | 2003-04-15 | 2005-12-14 | Warner Lambert Co | Derivados de prolina biciclicos [b]-condensados y sus usos para tratar afecciones artriticas. |
| MXPA05010165A (es) * | 2003-04-15 | 2005-11-16 | Warner Lambert Co | Derivados de prolina biciclicos [c]-condensados y su uso para el tratamiento de estados artriticos. |
| CN113372324A (zh) * | 2021-06-18 | 2021-09-10 | 山东大学苏州研究院 | 一种通过碘化锂催化合成螺环类化合物的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL58849A (en) * | 1978-12-11 | 1983-03-31 | Merck & Co Inc | Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them |
| DE3174844D1 (en) * | 1980-10-23 | 1986-07-24 | Schering Corp | Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them |
| DE3211397A1 (de) * | 1982-03-27 | 1983-11-10 | Hoechst Ag, 6230 Frankfurt | Spiro (4.(3+n))-2-aza-3-carbonsaeure-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung |
-
1983
- 1983-01-12 DE DE19833300774 patent/DE3300774A1/de not_active Withdrawn
-
1984
- 1984-01-09 DE DE8484100130T patent/DE3476067D1/de not_active Expired
- 1984-01-09 EP EP84100130A patent/EP0116276B1/de not_active Expired
- 1984-01-09 AT AT84100130T patent/ATE39931T1/de not_active IP Right Cessation
- 1984-01-10 ES ES528761A patent/ES8406880A1/es not_active Expired
- 1984-01-10 KR KR1019840000070A patent/KR910003185B1/ko not_active IP Right Cessation
- 1984-01-10 US US06/569,758 patent/US4620012A/en not_active Expired - Lifetime
- 1984-01-10 GR GR73477A patent/GR79158B/el unknown
- 1984-01-11 ZA ZA84213A patent/ZA84213B/xx unknown
- 1984-01-11 IE IE48/84A patent/IE56544B1/en not_active IP Right Cessation
- 1984-01-11 DK DK011984A patent/DK166586C/da active
- 1984-01-11 JP JP59002113A patent/JPH0759590B2/ja not_active Expired - Lifetime
- 1984-01-11 AU AU23229/84A patent/AU575308B2/en not_active Ceased
- 1984-01-11 PT PT77943A patent/PT77943B/pt not_active IP Right Cessation
- 1984-03-05 ES ES530290A patent/ES8500905A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0116276B1 (de) | 1989-01-11 |
| DE3476067D1 (en) | 1989-02-16 |
| ES528761A0 (es) | 1984-09-01 |
| ES8406880A1 (es) | 1984-09-01 |
| KR910003185B1 (ko) | 1991-05-22 |
| AU575308B2 (en) | 1988-07-28 |
| PT77943B (de) | 1986-05-30 |
| ES530290A0 (es) | 1984-11-01 |
| EP0116276A2 (de) | 1984-08-22 |
| DK11984A (da) | 1984-07-13 |
| IE840048L (en) | 1984-07-12 |
| ATE39931T1 (de) | 1989-01-15 |
| DK166586C (da) | 1993-11-08 |
| AU2322984A (en) | 1984-07-19 |
| DK166586B (da) | 1993-06-14 |
| KR840007585A (ko) | 1984-12-08 |
| DE3300774A1 (de) | 1984-07-12 |
| ES8500905A1 (es) | 1984-11-01 |
| PT77943A (de) | 1984-02-01 |
| EP0116276A3 (en) | 1985-11-27 |
| JPH0759590B2 (ja) | 1995-06-28 |
| ZA84213B (en) | 1984-08-29 |
| JPS59134765A (ja) | 1984-08-02 |
| IE56544B1 (en) | 1991-08-28 |
| DK11984D0 (da) | 1984-01-11 |
| US4620012A (en) | 1986-10-28 |
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