GR3031767T3 - Cyclopropane derivatives and antiviral agents containing the same. - Google Patents

Cyclopropane derivatives and antiviral agents containing the same.

Info

Publication number
GR3031767T3
GR3031767T3 GR990402857T GR990402857T GR3031767T3 GR 3031767 T3 GR3031767 T3 GR 3031767T3 GR 990402857 T GR990402857 T GR 990402857T GR 990402857 T GR990402857 T GR 990402857T GR 3031767 T3 GR3031767 T3 GR 3031767T3
Authority
GR
Greece
Prior art keywords
hydrogen atom
same
antiviral agents
agents containing
group
Prior art date
Application number
GR990402857T
Other languages
Greek (el)
Inventor
Takaaki Sekiyama
Osamu Ikemura
Tomoyuki Onishi
Takashi Tsuji
Satoshi Iwayama
Katsuya Suzuki
Yuko Ohmura
Masahiko Okunishi
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of GR3031767T3 publication Critical patent/GR3031767T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A cyclopropane derivative represented by the general formula (I) or a pharmaceutically acceptable salt thereof has antiviral activity and is suitable for inclusion in antiviral medicaments: <CHEM> wherein R<1> and R<2>, which may be the same or different, each represents a hydrogen atom or a group represented by the formula (1): <CHEM> (in which R<3> represents an alkyl group containing 1 to 6 carbon atoms), provided that at least one of R<1> and R<2> is not a hydrogen atom; X represents a hydrogen atom, a hydroxyl group, an amino group, or a halogen atom; and Y represents a hydrogen atom, a hydroxyl group, or an amino group.
GR990402857T 1993-11-18 1999-11-05 Cyclopropane derivatives and antiviral agents containing the same. GR3031767T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28902093 1993-11-18

Publications (1)

Publication Number Publication Date
GR3031767T3 true GR3031767T3 (en) 2000-02-29

Family

ID=17737794

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990402857T GR3031767T3 (en) 1993-11-18 1999-11-05 Cyclopropane derivatives and antiviral agents containing the same.

Country Status (10)

Country Link
EP (1) EP0654473B1 (en)
KR (1) KR950014110A (en)
CN (1) CN1041729C (en)
AT (1) ATE184282T1 (en)
CA (1) CA2136159A1 (en)
DE (1) DE69420514T2 (en)
DK (1) DK0654473T3 (en)
ES (1) ES2138052T3 (en)
GR (1) GR3031767T3 (en)
TW (1) TW282470B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives
US6703394B2 (en) 1996-02-16 2004-03-09 Medivir Ab Acyclic nucleoside derivatives
WO1999032490A1 (en) * 1997-12-19 1999-07-01 Bristol-Myers Squibb Company Prodrugs of lobucavir and methods of use
JP3709793B2 (en) * 2001-01-29 2005-10-26 株式会社村田製作所 Vibrating gyro, electronic device using the same, and self-diagnosis method of vibrating gyro
JP2004026695A (en) * 2002-06-24 2004-01-29 M's Science Corp Aqueous eye drop
GB0814065D0 (en) * 2008-08-01 2008-09-10 Univ Leuven Kath Use of nucleoside analogs as anti-koi herpes virus molecules

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8202626A (en) * 1982-06-29 1984-01-16 Stichting Rega V Z W DERIVATIVES OF 9- (2-HYDROXYETHOXYMETHYL) GUANINE.
US4617304A (en) * 1984-04-10 1986-10-14 Merck & Co., Inc. Purine derivatives
US4859680A (en) * 1984-04-10 1989-08-22 Merck & Co., Inc. Pyrimidine derivatives as antiviral compounds
AP55A (en) * 1987-08-15 1989-09-26 The Wellcome Foundation Ltd Therapeutic Acyclic Nucleosides
AU618436B2 (en) * 1988-12-19 1991-12-19 Wellcome Foundation Limited, The Antiviral cytosine and guanine derivatives
CA2051012C (en) * 1990-09-14 2002-04-02 David R. Borcherding Carbocyclic adenosine analogs useful as immunosupressants
DE69230349T2 (en) * 1991-03-05 2000-07-27 Ajinomoto Co., Inc. Cyclopropane derivative
JPH0680670A (en) * 1992-09-03 1994-03-22 Ajinomoto Co Inc Cyclopropane derivative and its production

Also Published As

Publication number Publication date
EP0654473A1 (en) 1995-05-24
TW282470B (en) 1996-08-01
KR950014110A (en) 1995-06-15
DE69420514D1 (en) 1999-10-14
CA2136159A1 (en) 1995-05-19
DE69420514T2 (en) 2000-05-18
DK0654473T3 (en) 2000-03-20
CN1041729C (en) 1999-01-20
EP0654473B1 (en) 1999-09-08
ATE184282T1 (en) 1999-09-15
ES2138052T3 (en) 2000-01-01
CN1111244A (en) 1995-11-08

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