GB936365A - Chemotherapeutic methyl-sulphonyl-phenyl compounds - Google Patents

Chemotherapeutic methyl-sulphonyl-phenyl compounds

Info

Publication number
GB936365A
GB936365A GB12035/61A GB1203561A GB936365A GB 936365 A GB936365 A GB 936365A GB 12035/61 A GB12035/61 A GB 12035/61A GB 1203561 A GB1203561 A GB 1203561A GB 936365 A GB936365 A GB 936365A
Authority
GB
United Kingdom
Prior art keywords
threo
sulphonyl
chemotherapeutic
methyl
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12035/61A
Inventor
Carlo Concilio
Piero Lanza
Mario Preti
Mario Portelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zambon SpA
Original Assignee
Zambon SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon SpA filed Critical Zambon SpA
Publication of GB936365A publication Critical patent/GB936365A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises d-threo and dl-threo isomers of a compound of the formula <FORM:0936365/IV(a)/1> and water-soluble salts thereof such as the sulphate and hydrochloride, and their preparation by treating the appropriate d-threo-or dl-threo-1-p-methylsulphonylphenyl-2-dichloroacetylamino-1, 3-propanediol with chloroacetyl chloride, converting the resulting chloroacetyl ester into its salt with hexamethylenetetramine and hydrolysing this salt with a strong acid to give the desired product in the form of its acid addition salt. Specifications 745,900, 770,277 and 936,366 are referred to.
GB12035/61A 1960-04-09 1961-04-04 Chemotherapeutic methyl-sulphonyl-phenyl compounds Expired GB936365A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT638360 1960-04-09

Publications (1)

Publication Number Publication Date
GB936365A true GB936365A (en) 1963-09-11

Family

ID=11121031

Family Applications (2)

Application Number Title Priority Date Filing Date
GB46861/62A Expired GB936366A (en) 1960-04-09 1961-04-04 Methylsulphonyl-phenyl compounds
GB12035/61A Expired GB936365A (en) 1960-04-09 1961-04-04 Chemotherapeutic methyl-sulphonyl-phenyl compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB46861/62A Expired GB936366A (en) 1960-04-09 1961-04-04 Methylsulphonyl-phenyl compounds

Country Status (4)

Country Link
DE (1) DE1221239B (en)
FR (1) FR1119M (en)
GB (2) GB936366A (en)
OA (1) OA01074A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2081584A1 (en) * 1970-03-24 1971-12-10 Sumitomo Chemical Co Chloramphenicol and thiamphenicol esters
US4188402A (en) * 1977-08-05 1980-02-12 Clesa S.P.A. Derivatives of the D-threo-1-phenyl-2-trifluoroacetamido-1,3-propandediol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1213714A (en) * 1957-11-07 1960-04-04 Erba Carlo Chloramphenicol derivatives and their preparation

Also Published As

Publication number Publication date
FR1119M (en) 1962-02-12
DE1221239B (en) 1966-07-21
OA01074A (en) 1968-08-07
GB936366A (en) 1963-09-11

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