GB936365A - Chemotherapeutic methyl-sulphonyl-phenyl compounds - Google Patents
Chemotherapeutic methyl-sulphonyl-phenyl compoundsInfo
- Publication number
- GB936365A GB936365A GB12035/61A GB1203561A GB936365A GB 936365 A GB936365 A GB 936365A GB 12035/61 A GB12035/61 A GB 12035/61A GB 1203561 A GB1203561 A GB 1203561A GB 936365 A GB936365 A GB 936365A
- Authority
- GB
- United Kingdom
- Prior art keywords
- threo
- sulphonyl
- chemotherapeutic
- methyl
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises d-threo and dl-threo isomers of a compound of the formula <FORM:0936365/IV(a)/1> and water-soluble salts thereof such as the sulphate and hydrochloride, and their preparation by treating the appropriate d-threo-or dl-threo-1-p-methylsulphonylphenyl-2-dichloroacetylamino-1, 3-propanediol with chloroacetyl chloride, converting the resulting chloroacetyl ester into its salt with hexamethylenetetramine and hydrolysing this salt with a strong acid to give the desired product in the form of its acid addition salt. Specifications 745,900, 770,277 and 936,366 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT638360 | 1960-04-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB936365A true GB936365A (en) | 1963-09-11 |
Family
ID=11121031
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB12035/61A Expired GB936365A (en) | 1960-04-09 | 1961-04-04 | Chemotherapeutic methyl-sulphonyl-phenyl compounds |
GB46861/62A Expired GB936366A (en) | 1960-04-09 | 1961-04-04 | Methylsulphonyl-phenyl compounds |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB46861/62A Expired GB936366A (en) | 1960-04-09 | 1961-04-04 | Methylsulphonyl-phenyl compounds |
Country Status (4)
Country | Link |
---|---|
DE (1) | DE1221239B (en) |
FR (1) | FR1119M (en) |
GB (2) | GB936365A (en) |
OA (1) | OA01074A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2081584A1 (en) * | 1970-03-24 | 1971-12-10 | Sumitomo Chemical Co | Chloramphenicol and thiamphenicol esters |
US4188402A (en) * | 1977-08-05 | 1980-02-12 | Clesa S.P.A. | Derivatives of the D-threo-1-phenyl-2-trifluoroacetamido-1,3-propandediol |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1213714A (en) * | 1957-11-07 | 1960-04-04 | Erba Carlo | Chloramphenicol derivatives and their preparation |
-
1961
- 1961-04-04 GB GB12035/61A patent/GB936365A/en not_active Expired
- 1961-04-04 GB GB46861/62A patent/GB936366A/en not_active Expired
- 1961-04-06 DE DEZ8658A patent/DE1221239B/en active Pending
- 1961-04-07 FR FR858090A patent/FR1119M/en active Active
-
1964
- 1964-12-30 OA OA51184A patent/OA01074A/en unknown
Also Published As
Publication number | Publication date |
---|---|
OA01074A (en) | 1968-08-07 |
DE1221239B (en) | 1966-07-21 |
GB936366A (en) | 1963-09-11 |
FR1119M (en) | 1962-02-12 |
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