GB2464610A - Antimicrobial cable - Google Patents
Antimicrobial cable Download PDFInfo
- Publication number
- GB2464610A GB2464610A GB0918418A GB0918418A GB2464610A GB 2464610 A GB2464610 A GB 2464610A GB 0918418 A GB0918418 A GB 0918418A GB 0918418 A GB0918418 A GB 0918418A GB 2464610 A GB2464610 A GB 2464610A
- Authority
- GB
- United Kingdom
- Prior art keywords
- group
- cable
- active agent
- polymer composition
- coupling agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 26
- 229920000642 polymer Polymers 0.000 claims abstract description 61
- 239000000203 mixture Substances 0.000 claims abstract description 54
- 150000001282 organosilanes Chemical class 0.000 claims abstract description 45
- -1 ethoxyl Chemical group 0.000 claims abstract description 43
- 239000007822 coupling agent Substances 0.000 claims abstract description 39
- 239000013543 active substance Substances 0.000 claims abstract description 37
- 238000000034 method Methods 0.000 claims abstract description 31
- 230000003641 microbiacidal effect Effects 0.000 claims abstract description 26
- 239000010457 zeolite Substances 0.000 claims abstract description 25
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical group [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 23
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 23
- 239000011701 zinc Chemical group 0.000 claims abstract description 23
- 229910052709 silver Inorganic materials 0.000 claims abstract description 22
- 239000004332 silver Substances 0.000 claims abstract description 22
- 229910021536 Zeolite Inorganic materials 0.000 claims abstract description 21
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims abstract description 21
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical group [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims abstract description 18
- 238000004519 manufacturing process Methods 0.000 claims abstract description 14
- 150000002484 inorganic compounds Chemical class 0.000 claims abstract description 13
- 229910010272 inorganic material Inorganic materials 0.000 claims abstract description 13
- 238000004320 controlled atmosphere Methods 0.000 claims abstract description 12
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 7
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000004599 antimicrobial Substances 0.000 claims abstract description 6
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical group [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 5
- ATJFFYVFTNAWJD-UHFFFAOYSA-N Tin Chemical group [Sn] ATJFFYVFTNAWJD-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229910052797 bismuth Inorganic materials 0.000 claims abstract description 5
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical group [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229910052793 cadmium Inorganic materials 0.000 claims abstract description 5
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical group [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 claims abstract description 5
- 229910052802 copper Inorganic materials 0.000 claims abstract description 5
- 239000010949 copper Chemical group 0.000 claims abstract description 5
- 239000011135 tin Chemical group 0.000 claims abstract description 5
- 229910052718 tin Inorganic materials 0.000 claims abstract description 5
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims abstract description 5
- 229920002554 vinyl polymer Polymers 0.000 claims abstract description 5
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 4
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 46
- 239000004408 titanium dioxide Substances 0.000 claims description 26
- 239000002131 composite material Substances 0.000 claims description 18
- 239000002270 dispersing agent Substances 0.000 claims description 17
- 238000013329 compounding Methods 0.000 claims description 16
- 150000001875 compounds Chemical class 0.000 claims description 16
- 229920001903 high density polyethylene Polymers 0.000 claims description 16
- 239000004700 high-density polyethylene Substances 0.000 claims description 16
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 14
- 239000004743 Polypropylene Substances 0.000 claims description 12
- 229920001155 polypropylene Polymers 0.000 claims description 12
- 239000004800 polyvinyl chloride Substances 0.000 claims description 12
- 239000004094 surface-active agent Substances 0.000 claims description 10
- 150000001993 dienes Chemical class 0.000 claims description 8
- HQQADJVZYDDRJT-UHFFFAOYSA-N ethene;prop-1-ene Chemical group C=C.CC=C HQQADJVZYDDRJT-UHFFFAOYSA-N 0.000 claims description 8
- 229920001897 terpolymer Polymers 0.000 claims description 8
- 239000004721 Polyphenylene oxide Substances 0.000 claims description 6
- 239000008187 granular material Substances 0.000 claims description 6
- 229920000570 polyether Polymers 0.000 claims description 6
- 229920005862 polyol Polymers 0.000 claims description 5
- 150000003077 polyols Chemical class 0.000 claims description 5
- 229930040373 Paraformaldehyde Natural products 0.000 claims description 4
- 239000004696 Poly ether ether ketone Substances 0.000 claims description 4
- 239000004698 Polyethylene Substances 0.000 claims description 4
- PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 claims description 4
- 239000004433 Thermoplastic polyurethane Substances 0.000 claims description 4
- MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 claims description 4
- 229910052918 calcium silicate Inorganic materials 0.000 claims description 4
- 239000000378 calcium silicate Substances 0.000 claims description 4
- AOWKSNWVBZGMTJ-UHFFFAOYSA-N calcium titanate Chemical compound [Ca+2].[O-][Ti]([O-])=O AOWKSNWVBZGMTJ-UHFFFAOYSA-N 0.000 claims description 4
- OYACROKNLOSFPA-UHFFFAOYSA-N calcium;dioxido(oxo)silane Chemical compound [Ca+2].[O-][Si]([O-])=O OYACROKNLOSFPA-UHFFFAOYSA-N 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 229910001430 chromium ion Inorganic materials 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- JAUGGEIKQIHSMF-UHFFFAOYSA-N dialuminum;dimagnesium;dioxido(oxo)silane;oxygen(2-);hydrate Chemical compound O.[O-2].[O-2].[Mg+2].[Mg+2].[Al+3].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O.[O-][Si]([O-])=O JAUGGEIKQIHSMF-UHFFFAOYSA-N 0.000 claims description 4
- 125000005843 halogen group Chemical group 0.000 claims description 4
- 150000002500 ions Chemical class 0.000 claims description 4
- 229910021645 metal ion Inorganic materials 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- 229920002492 poly(sulfone) Polymers 0.000 claims description 4
- 229920002530 polyetherether ketone Polymers 0.000 claims description 4
- 229920000573 polyethylene Polymers 0.000 claims description 4
- 229920006324 polyoxymethylene Polymers 0.000 claims description 4
- 229920001296 polysiloxane Polymers 0.000 claims description 4
- 150000004760 silicates Chemical class 0.000 claims description 4
- 229920002803 thermoplastic polyurethane Polymers 0.000 claims description 4
- NSBGJRFJIJFMGW-UHFFFAOYSA-N trisodium;stiborate Chemical compound [Na+].[Na+].[Na+].[O-][Sb]([O-])([O-])=O NSBGJRFJIJFMGW-UHFFFAOYSA-N 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 3
- 230000003750 conditioning effect Effects 0.000 claims description 3
- 238000001125 extrusion Methods 0.000 claims description 3
- 238000001746 injection moulding Methods 0.000 claims description 3
- 238000004898 kneading Methods 0.000 claims description 3
- NLHHRLWOUZZQLW-UHFFFAOYSA-N Acrylonitrile Chemical compound C=CC#N NLHHRLWOUZZQLW-UHFFFAOYSA-N 0.000 claims description 2
- NOWKCMXCCJGMRR-UHFFFAOYSA-N Aziridine Chemical compound C1CN1 NOWKCMXCCJGMRR-UHFFFAOYSA-N 0.000 claims description 2
- 239000004593 Epoxy Substances 0.000 claims description 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 claims description 2
- 239000005977 Ethylene Substances 0.000 claims description 2
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims description 2
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims description 2
- 239000004417 polycarbonate Substances 0.000 claims description 2
- 229920000515 polycarbonate Polymers 0.000 claims description 2
- 229920000647 polyepoxide Polymers 0.000 claims description 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 2
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 2
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical group [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 abstract 1
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 abstract 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 abstract 1
- 229910052804 chromium Chemical group 0.000 abstract 1
- 239000011651 chromium Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 description 34
- 229920003031 santoprene Polymers 0.000 description 11
- 241000894006 Bacteria Species 0.000 description 8
- 230000000694 effects Effects 0.000 description 6
- 229910044991 metal oxide Inorganic materials 0.000 description 6
- 229920000915 polyvinyl chloride Polymers 0.000 description 6
- 239000000284 extract Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 4
- 231100000263 cytotoxicity test Toxicity 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 230000004044 response Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
- 125000000524 functional group Chemical group 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 229920002614 Polyether block amide Polymers 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000003242 anti bacterial agent Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 230000000249 desinfective effect Effects 0.000 description 2
- 239000000835 fiber Substances 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 230000009257 reactivity Effects 0.000 description 2
- 241000588722 Escherichia Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 241000720945 Hosta Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000003749 cleanliness Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000000356 contaminant Substances 0.000 description 1
- 238000011437 continuous method Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000000428 dust Substances 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 239000000945 filler Substances 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000000155 melt Substances 0.000 description 1
- 150000004706 metal oxides Chemical class 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 239000013307 optical fiber Substances 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000002787 reinforcement Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013026 undiluted sample Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/12—Chemical modification
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01B—CABLES; CONDUCTORS; INSULATORS; SELECTION OF MATERIALS FOR THEIR CONDUCTIVE, INSULATING OR DIELECTRIC PROPERTIES
- H01B3/00—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties
- H01B3/18—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties mainly consisting of organic substances
- H01B3/30—Insulators or insulating bodies characterised by the insulating materials; Selection of materials for their insulating or dielectric properties mainly consisting of organic substances plastics; resins; waxes
Landscapes
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Abstract
The present invention relates to a cable and a cord suitable for use in a hospital environment or in a controlled atmosphere environment, and to the method for the manufacture thereof and to the use thereof. In particular, the invention provides a cable comprising: i) a polymer composition; ii) at least one active agent composed of an antimicrobial or microbicidal inorganic compound; said at least one active agent being coupled to the polymer composition via iii) at least one organosilane coupling agent; wherein ii) is selected from silicate, zeolite, titanate or antimonate substituted with silver, copper, zinc, tin, bismuth, lead, cadmium or chromium, and wherein iii) has the formula R13SiR2, wherein R1is methoxyl or ethoxyl, and R2is a) vinyl, b) phenyl, c) aminoalkylaminoalkyl having independently C2or C3alkyl groups, d) C1-4linear or branched alkyl optionally substituted with suphanyl or halogen.
Description
INTELLECTUAL
. .... PROPERTY OFFICE Application No. GBO9 18418.5 RTM Date:19 February 2010 The following terms are registered trademarks and should be read as such wherever they occur in this document: Santoprene Hostalen Intellectual Property Office is an operating name of the Patent Office www.ipo.gov.uk Cable and/or cord suitable for use in a hospital environment or in a controlled atmosphere environment and method for the manufacture thereof The present invention relates to a cable and a cord suitable for use in a hospital environment or in a controlled atmosphere environment, and to the method for the manufacture thereof and to the use thereof.
It is often critical, in a hospital environment or in a controlled atmosphere environment, such as chambers under positive pressure or under negative pressure, to control the entry and/or the departure of pollutants or contaminants (bacteria, dust, and the like) and necessary to provide an impeccable quality of cleanliness, indeed even sterilization, of the equipment or device used. Controlling these various parameters makes it possible to protect staff and/or patients from any possible contamination and/or to guarantee a healthy environment for the manufacture of products, such as pharmaceuticals or semiconducting devices.
In the specific case of medical centres and hospitals, numerous electronic and computer devices are installed. The disinfecting, which is a regulatory requirement, of the surfaces of these items of equipment and of their peripheral components, such as cables and cords, has to be carried out regularly using disinfectants. It would thus be advantageous to render these surfaces of items of equipment and these peripheral components antibacterial or bactericidal from their manufacture in order to eliminate or reduce disinfecting operations.
Patent Application JP 11-199732 describes a cable composed of an antibacterial external coating, the composition of which is mainly composed of a polymer and of an antibacterial agent. Although this type of cable exhibits antibacterial properties, it is not sufficiently reliable over time.
There thus exists a real need to provide an item of equipment or a device, in particular a cable or a cord, which is more effective than existing cables.
The aim of the invention is to devise a cable or a cord which makes it possible to effectively minimize or to prevent risks of contamination and to provide a method for manufacturing this cable or this cord.
According to its first subject matter, the invention relates to a cable suitable for use in a hospital environment or in a controlled atmosphere environment, said cable comprising: -a polymer composition; -at least one active agent composed of an antimicrobial or microbicidal inorganic compound, said inorganic compound preferably being chosen from the group consisting of silicates, zeolites, titanates and antimonates, in particular calcium silicate, calcium titanate, sodium antimonate and magnesium aluminometasilicate, the ions of which have been replaced by one or more antimicrobial or microbicidal metal ion(s) selected from silver, copper, zinc, tin, bismuth, lead, cadmium or chromium ions; -said at least one active agent being coupled to the polymer composition via at least one organosilane coupling agent, preferably of formula (I): R' R1 (I) in which: * R1 denotes a methoxyl (CH3-O-or MeO-) or ethoxyl (CH3-CH2-O-or EtO-) group; and * R2 is chosen from the group consisting of the vinyl (H2C=CH-) group, the phenyl (C6H5-) group, the aminoalkylaminoalkyl group, in which the alkyls independently have from 2 to 3 carbon atoms, and the linear or branched CC4 alkyl group, optionally substituted by a sulphanyl group or by a halogen atom.
Generally, the term "antimicrobial" is understood to mean an agent which inhibits the growth or prevents the proliferation of microorganisms.
Microorganisms comprise bacteria, viruses, protozoa and fungi, including yeasts and moulds. The term "antimicrobial" thus encompasses the terms "antibacterial", "antifungal" and "antiviral".
Analogously, the expression "microbicidal compound" represents an agent which destroys or kills microorganisms. The expression "microbicidal compound" encompasses, inter alia, bactericidal and fungicidal compounds.
The coupling agent is a compound which makes it possible mainly to connect said at least one active agent of inorganic nature to said polymer composition of organic nature and to disperse said at least one active agent in said polymer composition. This linkage, also known as "coupling", of chemical and/or physical nature is provided, in the present case, by an organosilane which exhibits two types of reactive functional groups: one of the two functional groups will react with the inorganic compound, that is to say with said at least one active agent, and the remaining functional group with the polymer composition.
Said at least one organosilane coupling agent employed in the present invention preferably comprises: -three alkoxyl groups R1 (either methoxyl or ethoxyl) which, after hydrolysis (either by addition of water or by the presence of residual water originating from the active agent), are converted into hydroxyl (-OH) groups. The latter groups then react with the active agent; -a group R2, as defined above, which reacts chemically and/or physically with the polymer composition. The polymer composition is chosen depending on its reactivity with respect to that of the R2 group of the organosilane coupling agent.
According to a particularly advantageous alternative embodiment of the invention, said aminoalkylaminoalkyl group is aminoethylaminopropyl (H2N-CH2-CH2-NH-CH2-CH2--CH2-).
According to another particularly advantageous alternative embodiment of the invention, said C-C4 alkyl group is isobutyl or mercaptopropyl.
According to yet another particularly advantageous alternative embodiment of the invention, said at least one organosifane coupling agent is chosen from the group consisting of: MeQ EtO CH2 CH2 EtO.// OMe OFt (a) (Tb) MeO MeO MeO MeOSH OMe OMe
I I
(Ia) (Id) MeO MeO MeO. NH2 OMe and OMe (Je) (If) According to an advantageous embodiment of the invention, the polymer composition is chosen from polyvinyl chloride (PVC), polyethylene (PE), preferably high density polyethylene (HDPE), polypropylene (PP), polytetrafi uoroethylene (PTFE), poly(styrene/butadiene/acrylonitrile) (ABS), poly(styrene/butadiene/styrene) (SBS), polyca rbonate (PC), polyoxymethylene (POM), poly(ethylenimine) (PEI), polysulphone (PSU), polyetheretherketone (PEEK), polyether block amide (PEBA), thermoplastic polyurethanes (TPU), epoxy polymers (or polyepoxide), silicones (or polysiloxanes), fluorinated ethylene/propylene copolymer (FEP), ethylene/tetrafluoroethylene copolymer (ETFE), thermoplastic elastomers (TPE5) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene, and a blend of at least two of these polymers.
According to a particularly advantageous alternative embodiment of the invention, said polymer composition is chosen from polyvinyl chloride (PVC), high density polyethylene (HDPE) and thermoplastic elastomers (TPE5) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
According to a specific embodiment of the invention, said at least one active agent is an antibacterial or bactericidal inorganic compound.
The term "antibacterial" is understood to mean an agent which inhibits the growth or prevents the proliferation of bacteria and the term "bactericidal" is understood to mean an agent which destroys or kills bacteria.
According to an advantageous alternative embodiment of the invention, said at least one active agent comprises silver ions.
According to another advantageous alternative embodiment of the invention, said at least one active agent is a zeolite comprising silver ions and optionally zinc ions.
According to yet another advantageous alternative embodiment of the invention, said zeolite comprises from 1 to 2% by weight of zinc and from 0.2 to 0.8% by weight of silver, with respect to the total weight of the zeolite based on silver and on zinc. Preferably, said zeolite comprises 1.36% by weight of zinc and 0.44% by weight of silver, with respect to the total weight of the zeolite based on silver and on zinc.
According to an advantageous embodiment of the invention, said cable additionally comprises titanium dioxide.
According to another advantageous embodiment of the invention, said cable additionally comprises a dispersant or surface-active agent, preferably chosen from the group consisting of a polyether polyol and an ethoxylated nonionic fluorinated surface-active agent of formula F(CF2CF2)CH2CH2o(CH2CH2o)H where x = 0 to 15 and y = 1 to 7.
According to yet another advantageous embodiment of the invention, said cable comprises: -from 0.1 to 5.0% by weight of said at least one active agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant; and/or -from 0.02 or 0.05 to 1.0% by weight of said at least one organosilane coupling agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant.
Said cable preferably comprises from 0.1 to 1.0%, with 1.0% excluded, and more advantageously from 0.1 to 0.5% by weight of said at least one active agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant.
In the presence of titanium dioxide and/or of dispersant in the cable, the combination to be considered for the total weight is formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent, said titanium dioxide and/or said dispersant.
According to an advantageous alternative embodiment of the invention, said cable comprises: -from 0.02 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes I and Je; or -from 0.05 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes a, Ib, Id and I. According to an advantageous embodiment of the invention, said cable comprises from 0.1 to 1.5% by weight of titanium dioxide, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent, said titanium dioxide and optionally a dispersant, According to its second subject matter, the invention relates to a cord composed of a cable as described above and at least one connecting element, said at least one connecting element preferably comprising an electrical connector, a USB connector, and the like. "Cord" is thus understood to mean a device comprising a cable and one or more connecting elements. The connecting element can comprise any type of connector, in particular a connector for the transmission of data, such as a USB or RJ45 connector; or also a connector for the transmission of current, such as a two-phase or three-phase plug or socket, and the like.
Likewise, the cable can denote any type of cable, in particular a single fibre or multi-fibre cable, a flat cable, and/or a coaxial cable; the cable can also be a cable used for the transfer of fluids (gases, liquids) or for the transmission of optical signals via at least one optical fibre or of pressure signals via a fluid.
Another subject matter of the invention is the use of the cable as described above or of the cord as defined above in a hospital environment or in a controlled atmosphere environment.
According to its fourth subject matter, the invention relates to a method for manufacturing a cable or cord suitable for use in a hospital environment or in a controlled atmosphere environment, characterized in that it comprises the steps consisting in: a. preparing a premix in a mixing device at ambient temperature (15-25°C), said premix comprising: > at least one active agent composed of an antimicrobial or microbicidal inorganic compound, said inorganic compound preferably being chosen from the group consisting of silicates, zeolites, titanates and antimonates, in particular calcium silicate, calcium titanate, sodium antimonate and magnesium aluminometasilicate, the ions of which have been replaced by one or more antimicrobial or microbicidal metal ion(s) selected from silver, copper, zinc, tin, bismuth, lead, cadmium or chromium ions; at least one organosilane coupling agent, preferably of formula (I): R' (I') in which: * R' denotes a methoxyl (CH3-O-) or ethoxyl (CH3-CH2-O-) group; and * R2 is chosen from the group consisting of the vinyl (H2C=CH-) group, the phenyl (C6H5-) group, the aminoalkylaminoalkyl group, in which the alkyls independently have from 2 to 3 carbon atoms, and the linear or branched C1-C4 alkyl group, optionally substituted by a sulphanyl group or by a halogen atom; > optionally titanium dioxide; and > optionally a dispersant or surface-active agent, preferably chosen from the group consisting of a polyether polyol and an ethoxylated nonionic fluorinated surface-active agent of formula F(CF2CF2)yCH2CH2O(CH2CH2o)H where x = 0 to 15 and y 1 to 7; b. continuously compounding: by feeding an extruder with a polymer composition and the premix obtained in the previous step, said extruder kneading the premix with the polymer composition at temperatures of between 150°C and 255°C; and by conditioning the product resulting from the compounding, known as compound or composite, in the form of granules once the composite has cooled; and c. forming the cable by a sheath extrusion operation, or a method of injection moulding using the composite granules.
Compounding is a method which makes possible the melt blending of plastics and additives. This method has the result of modifying certain physical, thermal or indeed even aesthetic features (by the introduction of colouring metal oxide(s)) of the plastic. By incorporating a broad range of additives, fillers and reinforcements, it is possible to obtain a large number of conductivity, flame retardance or wear resistance properties and/or a variety of advantageous structural properties. In our case, the compounding step according to the present invention makes it possible to render the composite antimicrobial or microbicidal. The final product resulting from the compounding step is known as compound or composite.
One of the difficulties encountered in the prior art in manufacturing composites intended for the production of antibacterial cables lies in the complexity of the method employed. When a composite is mainly formed from a polymer and an antibacterial inorganic compound, a good degree of homogeneity of the composite can only be achieved only after multiple passes (at least two passes) through a compounder (machine which makes it possible to carry out the compounding step). Such a method involves the use of numerous devices in series in order to make possible a continuous method or else the use of a single compounder in a noncontinuous method. The method for manufacturing an antibacterial cable or cord of the prior art is consequently relatively expensive.
The method of the present invention effectively solves the problems encountered in the prior art. Said method makes it possible to manufacture an antimicrobial or microbicidal, in particular antibacterial or bactericidal, cable or cord which exhibits a uniform antimicrobial or microbicidal activity. This uniform antimicrobial or microbicidal activity is based on the homogeneity of the blend obtained from the polymer composition and the premix. In other words, said activity depends on the homogeneity of the composite resulting from the compounding step. The achievement of such a homogeneity is made possible by the formulation of the composite (choice of the combination of the compounds constituting the composite) and/or by the step of preparation of the premix, followed by the implementation of the compounding step.
Surprisingly, the inventors have discovered that the method of the invention makes it possible to reduce the amount of the active agent used while retaining the desired antimicrobial or microbicidal activity. The method of the present invention thus provides a solution which is both simple to implement and economically advantageous.
According to a particularly advantageous alternative embodiment of the method, the compounding step is carried out at temperatures of: -between 150°C and 255°C, when the polymer composition is composed of high density polyethylene (HDPE); -between 160°C and 255°C, when the polymer composition is composed of polyvinyl chloride (PVC); -between 170°C and 255°C, when the polymer composition is composed of thermoplastic elastomers (TPEs) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
According to an advantageous embodiment of the method, said method additionally comprises a step consisting in: d. forming a cord from the cable obtained in step c and at least one connecting element, said at least one connecting element preferably comprising an electrical connector or a USB connector.
The method can be employed in the manufacture of cables or cords as defined above, according to any one of their embodiments or alternative forms.
According to an advantageous embodiment of the method, said premix comprises titanium dioxide.
According to another advantageous embodiment of the method, said premix comprises a dispersant or surface-active agent, preferably chosen from the group consisting of a polyether polyol and an ethoxylated nonionic fluorinated surface-active agent of formula F(CF2CF2)yCH2CH2O(CH2CH2O)H where x = 0 to 15 and y = 1 to 7.
According to yet another advantageous embodiment of the method, said premix comprises: from 0.1 to 5.0% by weight of said at least one active agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant; and/or -from 0.02 or 0.05 to 1.0% by weight of said at least one organosilane coupling agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant.
According to an advantageous alternative embodiment of the method, said premix comprises: -from 0.02 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes I and Ie or -from 0.05 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes a, Ib, Id and I. According to an advantageous embodiment of the method, said premix comprises from 0.1 to 1.5% by weight of titanium dioxide, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent, said titanium dioxide and optionally a dispersant.
Thus, the invention makes it possible to obtain a cable or a cord suitable for use in a hospital environment or in a controlled atmosphere environment which exhibits a uniform antimicrobial or microbicidal, in particular antibacterial or bactericidal, activity over the surface of the cable or cord, The cable or cord according to the present invention thus effectively solves the technical problems stated by virtue of the combination of the compounds (the polymer composition, the active agent and the organosilane coupling agent) included in the cable or cord. The active agent and the organosilane coupling agent are homogeneously distributed in the polymer composition. The combination of these compounds thus provides an optimum activity of the active agent, in this instance the antimicrobial or microbicidal inorganic compound, which, used in a smatter amount than in the prior art, makes it possible to obtain a cable or cord having antimicrobial or microbicidal properties at least comparable and/or superior to those of the cables or cords of the prior art.
Finally, the invention provides an effective method for manufacturing a cable or cord suitable for use in a hospital environment or in a controlled atmosphere environment. The step of preparation of the premix, followed by the implementation of the compounding step, makes it possible to obtain a homogeneous composite and thus to confer, on the polymer composition, uniform antimicrobial or microbicidal properties.
Other aims, characteristics and advantages of the invention will become clearly apparent to a person skilled in the art subsequent to the reading of the examples, which are given solely by way of illustration and which should not in any way limit the scope of the invention.
The examples form an integral part of the present invention and any feature appearing novel with respect to any state of the prior art from the description taken as a whole, including the examples, forms an integral part of the invention in the function thereof and in the generality thereof. Thus, each example has a general scope.
Furthermore, in the examples, all the percentages are given by weight, unless otherwise indicated, and the temperature is expressed in degrees Celsius, unless otherwise indicated, and the pressure is atmospheric pressure, unless otherwise indicated.
Examoles of the imDlementation of the invention Example 1 Cable or cord 1 A premix is prepared in a mixing device at ambient temperature (15-25°C) from: -a zeolite comprising 1.36% by weight of zinc and 0.44°k by weight of silver, with respect to the total weight of the zeolite based on silver and on zinc. Said zeolite has antimicrobial or microbicidal properties; -one or two organosilane coupling agent(s); -titanium dioxide.
Compounding is carried out continuously: > by feeding an extruder with a polymer composition or a polymer (in this instance PVC) and the premix obtained above, said extruder kneading the premix with the polymer at temperatures of between 160°C and 255°C; and by conditioning the composite in the form of granules once it has cooled.
The cable is formed by a sheath extrusion operation, or a method of injection moulding using the composite granules.
A cord is formed from the cable obtained and at least one connecting element, said at least one connecting element preferably comprising an electrical connector or a USB connector.
Example 1 of the implementation of the invention is illustrated in the following table, the amounts and the natures of the compounds included in the cable or cord being shown.
Zeolite having 136% by weight of zinc and 0.44% Antimicrobial or by weight of silver, with 0 5°! microbicidal compound respect to the total weight ° of the zeolite based on _________________________ silver_and_on_zinc _________________________ 1st organosilane If 0.3% 2' organosilane 0.2% Metal oxide Titanium dioxide 0.3% Type of polymer PVC 98.7% Example 2 -Cable or cord 2 A cable or cord 2 is manufactured as described in Example 1. However, the compounding step is carried out at temperatures of between 170°C and 255°C.
Zeolite having 1.36% by weight of zinc and 0.44% Antimicrobial or by weight of silver, with 0 5°! microbicidal compound respect to the total weight 0 of the zeolite based on _________________________ silver_and_on_zinc _________________________ 1st organosilane If 0.3% 2 organosilane Ic 0.2% Metal oxide Titanium dioxide 0.3% Type of polymer Santoprene*l 98.7% *1 this polymer corresponds to a thermoplastic elastomer (TPE) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
Example 3 -Cable or cord 3 A cable or cord 3 is manufactured as described in Example 2.
ZeoUte having 136% by weight of zinc and 0.44% Antimicrobial or by weight of silver, with 0 5°! microbicidal compound respect to the total weight ° of the zeolite based on _________________________ silver_and_on_zinc _________________________ Organosilane Id 0.3% Metal oxide Titanium dioxide 0.2% Type of polymer Santoprene*' 99.0% * this polymer corresponds to a thermoplastic elastomer (TPE) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
Example 4 -Cable or cord 4 A cable or cord 4 is manufactured as described in Example 1. However, the compounding step is carried out at temperatures of between 150°C and 255°C.
Zeolite having 1.36% by weight of zinc and 0.44% Antimicrobial or by weight of silver, with 0 5°/ microbicidal compound respect to the total weight 0 of the zeolite based on silver_and_on_zinc _________________________ iorosilan _____________________ 0.3% 2 organosflane le 0.2% Metal oxide Titanium dioxide ___________________ Type of polymer ien 98.7% *2 this polymer corresponds to a high density polyethylene (HDPE).
Example 5 -Cable or cord 5 A cable or cord 5 is manufactured as described in Example 4.
Zeolite having 1.36% by weight of zinc and 0.44% Anttmicrobial or by weight of silver, with 0 50/ microbicidal compound respect to the total weight of the zeolite based on _________________________ silver_and_on_zinc _________________________ 1st organosilane a O.3% 2 organosilane C 0.2% Metal oxide Titanium dioxide O.3% Type of polymer Hostalen*2 98.7% *2 this polymer corresponds to a high density polyethylene (HDPE).
Example 6 -Antibacterial or bactericidal activity of the cable or cord obtained Tests relating to the antibacterial or bactericidal activity are carried out according to Japanese Standard JIS Z 2801: 2000 from the cables or cords of the present invention. The results of these experiments are presented in the two tables below.
The controls are composed of the pure polymers and Tests 1 to 5 correspond respectively to the cables or cords obtained in Examples 1 to 5.
Staphylococcus aureus strain After incubating at 37°C for 24 h Example Type of polymer C4 log (C4)J E4 log (E4) log (C4) -log (E4) Control PVC 14 352 4.16 ____ _________ ________________ 1 PVC ______ ______ 32 1.50 2.66 Control Santoprene*l 482 350 5.68 ____ __________ 2 Santoprene*l _______ _______ 0 Bactericidal Control Santoprene*l 482 255 5.68 3 Santoprene*' _______ _______ 0 __________ Bactericidal Control Hostalen*2 478 465 5.68 4 Hostalen*2 _______ 0 Bactericidal Control Hostaien*2 13 946 4.14 Hostalen*2 ______ ______ 56 1.75 2.39 1) Ct24: the mean number of the bacteria counted in the case of the control, namely nonantibacterial, cable, after incubating for 24 hours.
2) Et24: the mean number of the bacteria counted in the case of the test cable after incubating for 24 hours. When Et24 is zero, the activity is bactericidal.
3) log (Cr24) -log (Et24): the activity is antibacterial when it is greater than 1.00.
Escherichia coil strain After incubating at 37°C for 24 h
______ ____________ _____ ______ _____ ______ _______________
Example Type of polymer! C4 log (C4) E4 log (E4) log (C4) -log (E4) Control PVC 4044 3.60 _____ ______ ________________ 1 PVC ______ ______ 15 1.17 2.43 Control Santoprene*l 20 125 4.30 _____ ______ ________________ 2 Santoprene*' ______ _______ 0 ______ Bactericidal Control Santoprene*' 20 585 4.31 _____ _______ _________________ 3 Santoprene*l ______ _______ 0 _______ Bactericidal Control Hosta$en*2 21 897 4.34 _____ _______ _________________ 4 Hostalen*2 ______ _______ 0 _______ Bactericidal Control Hostalen* 876 526 5.94 ______ _______ __________________ Hostalen*2 _______ 7765 3.87 2.07 1) Cr24: the mean number of the bacteria counted in the case of the control, namely nonantibacterial, cable, after incubating for 24 hours.
2) E4: the mean number of the bacteria counted in the case of the test cable after incubating for 24 hours. When Et24 is zero, the activity is bactericidal.
3) log (Ct24) -log (E24): the antibacterial activity is regarded as effective when it is greater than 1.00.
The homogeneity of the composite included in the cable or cord makes it possible to use a smaller amount of the antibacterial or bactericidal agent in a cable or cord of the present invention. Said cable or cord exhibits either an antibacterial activity or a bactericidal activity at least comparable and/or superior to those of the cables or cords of the
prior art.
Example 7 -Cytotoxicity. sensitivity and irritation tests Cytotoxicity test A cytotoxicity test is carried out according to Standard ISO 10993-5: 1999 from the cable or cord obtained in Example 1.
The cytotoxicity test consists in counting the percentage of living cells after exposure of a culture of mouse fibroblast cells to an extract solution, prepared from the cable or cord of the present invention, at different concentrations. This test thus makes it possible to evaluate the biological reactivity of a culture of mammal cells with regard to the extract solutions prepared from the cable or cord of the present invention.
Results: the response obtained is of level 1 (very low) from the preparation of an undiluted sample and the response is of level 0 (no response) from extract solutions diluted to �, � and 1/8.
The cytotoxicity test from the cable or cord of the present invention is in accordance with the requirements of Standard USP 31 (United States Pharmacopoeia) for a level of response not exceeding 2 (low).
Sensitivity and irritation tests A sensitivity and irritation test is carried out according to Standard ISO 10993-10: 2002 from the cable or cord obtained in Example 1.
These tests make it possible to estimate the sensitization and/or irritation potential of the extracts obtained from the cable or cord of the present invention when the extracts are injected intradermally.
Results: the cable or cord of the present invention was evaluated as being nonsensitizing and nonirritating.
Claims (19)
- CLAIMS1. Cable suitable for use in a hospital environment or in a controlled atmosphere environment, characterized in that it comprises: -a polymer composition; -at least one active agent composed of an antimicrobial or microbicidal inorganic compound, said inorganic compound preferably being chosen from the group consisting of silicates, zeolites, titanates and antimonates, in particular calcium silicate, calcium titanate, sodium antimonate and magnesium aluminometasilicate, the ions of which have been replaced by one or more antimicrobial or microbicidal metal ion(s) selected from silver, copper, zinc, tin, bismuth, lead, cadmium or chromium ions; -said at least one active agent being coupled to the polymer composition via at least one organosilane coupling agent, preferably of formula (I): R1 it: (I) in which: * R' denotes a methoxyl (CH3-O-) or ethoxyl (CH3-CH2-O-) group, and * R2 is chosen from the group consisting of the vinyl (H2C=CH-) group, the phenyf (C6H5-) group, the aminoalkylaminoalkyl group, in which the alkyls independently have from 2 to 3 carbon atoms, and the linear or branched C1c4 alkyl group, optionally substituted by a sulphanyl group or by a halogen atom.
- 2. Cable according to Claim 1, characterized in that said aminoalkylam inoalkyl group is aminoethylaminopropyl (H2N-CH2-CH2-NH-CH2-CH2-CH2-).
- 3. Cable according to Claim 1 or 2, characterized in that said C1-C4 alkyl group is isobutyl or mercaptopropyl.
- 4. Cable according to any one of Claims 1 to 3, characterized in that said at least one organosilane coupling agent is chosen from the group consisting of: MeQ EtO OH2 OH2 EtO-
- 5.c2 ONe GEtI(Ia) (Ib) MeO MeO MeO MeO.SH OMe OMeF F(Ia) (ci) MeG MeO MeO. MeO. NH2 OMe, and OMe GEe) (If) 5. Cable according to any one of Claims ito 4, characterized in that the polymer composition is chosen from polyvinyl chloride (PVC), polyethylene (PE), preferably high density polyethylene (HDPE), polypropylene (PP), polytetrafluoroethylene (PTFE), poly(styrene/butadiene/acrylonitrile) (ABS), poly(styrene/butadiene/styrene) (SBS), polycarbonate (PC), polyoxymethylene (POM), poly(ethylenimine) (PEI), polysul phone (PSU), polyetheretherketone (PEEK), polyether block am ide (PEBA), thermoplastic polyurethanes (TPU), epoxy polymers (or polyepoxide), silicones (or polysiloxanes), fluorinated ethylene/propylene copolymer (FEP), ethylene/tetrafluoroethylene copolymer (ETFE), thermoplastic elastomers (IPEs) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene, and a blend of at least two of these polymers.
- 6. Cable according to Claim 5, characterized in that said polymer composition is chosen from polyvinyl chloride (PVC), high density polyethylene (HDPE) and thermoplastic elastomers (IPEs) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
- 7. Cable according to any one of Claims 1 to 6, characterized in that said at least one active agent comprises silver ions.
- 8. Cable according to any one of Claims 1 to 7, characterized in that said at least one active agent is a zeolite comprising silver ions and optionally zinc ions.
- 9. Cable according to Claim 8, characterized in that said zeolite comprises from 1 to 2% by weight of zinc and from 0.2 to 08% by weight of silver, with respect to the total weight of the zeolite based on silver and on zinc.
- 10. Cable according to any one of Claims 1 to 9, characterized in that it additionally comprises titanium dioxide.
- 11. Cable according to any one of Claims 1 to 10, characterized in that it additionally comprises a dispersant or surface-active agent, preferably chosen from the group consisting of a polyether polyol and an ethoxylated nonionic fluorinated surface-active agent of formula F(CF2CF2)YCH2CH2O(CH2CH2O)XH where x = 0 to 15 and y = 1 to 7.
- 12. Cable according to any one of Claims 1 to 11, characterized in that it comprises: -from 0.1 to 5.0% by weight of said at least one active agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant; and/or -from 0.02 or 0.05 to 1.0% by weight of said at least one organosilane coupling agent, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent and optionally the titanium dioxide and a dispersant.
- 13. Cable according to Claim 12, characterized in that it comprises: -from 0.02 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes I and le; or -from 0.05 to 1.0% by weight of said at least one organosilane coupling agent when said at least one coupling agent is chosen from the organosilanes a, Ib, Id and Jr*
- 14. Cable according to any one of Claims 1 to 13, characterized in that it comprises from 0.1 to 1.5% by weight of titanium dioxide, with respect to the total weight of the combination formed by said polymer composition, said at least one active agent, said at least one organosilane coupling agent, said titanium dioxide and optionally a dispersant.
- 15. Cord composed of a cable according to any one of Claims 1 to 14 and at least one connecting element, said at least one connecting element preferably comprising an electrical connector or a USB connector.
- 16. Use of the cable according to any one of Claims 1 to 14 or of the cord according to Claim 15 in a hospital environment or in a controlled atmosphere environment.
- 17. Method for manufacturing a cable or cord suitable for use in a hospital environment or in a controlled atmosphere environment, characterized in that it comprises the steps consisting in: a. preparing a premix in a mixing device at ambient temperature (15-25°C), said premix comprising: > at least one active agent composed of an antimicrobial or microbicidal inorganic compound, said inorganic compound preferably being chosen from the group consisting of silicates, zeolites, titanates and antimonates, in particular calcium silicate, calcium titanate, sodium antimonate and magnesium aluminometasilicate, the ions of which have been replaced by one or more antimicrobial or microbicidal metal ion(s) selected from silver, copper, zinc, tin, bismuth, lead, cadmium or chromium ions; > at least one organosilane coupling agent, preferably of formula (I): R1 R2I R1 (I)in which: R' denotes a methoxyl (CH3O) or ethoxyl (CH3CH2O-) group; and R2 is chosen from the group consisting of the vinyl (H7C=CH-) group, the phenyl (C6H5-) group, the aminoalkylaminoalkyl group, in which the alkyls independently have from 2 to 3 carbon atoms, and the linear or branched C1-C4 alkyl group, optionally substituted by a suiphanyl group or by a halogen atom; > optionally titanium dioxide; and optionally a dispersant or surface-active agent, preferably chosen from the group consisting of a polyether polyol and an ethoxylated nonionic fluorinated surface-active agent of formula F(CF2CF2)CH2CH2O(CH2CH2O)H where x = 0 to 15 and y = I to 7; b. continuously compounding: > by feeding an extruder with a polymer composition and the premix obtained in the previous step, said extruder kneading the premix with the polymer composition at temperatures of between 150°C and 255°C; and > by conditioning the product resulting from the compounding, known as compound or composite, in the form of granules once the composite has cooled; and c. forming the cable by a sheath extrusion operation, or a method of injection moulding using the composite granules.
- 18. Method according to Claim 17, characterized in that the compounding step is carried out at temperatures of: -between 150°C and 255°C, when the polymer composition is composed of high density polyethylene (HDPE); -between 160°C and 255°C, when the polymer composition is composed of polyvinyl chloride (PVC); * between 170°C and 255°C, when the polymer composition is composed of thermoplastic elastomers (TPE5) resulting from a blend of EPDM (ethylene/propylene/diene terpolymer) and polypropylene.
- 19. Method according to Claim 17 or 18, characterized in that it additionally comprises a step consisting in: d forming a cord from the cable obtained in step c and at least one connecting element, said at least one connecting element preferably comprising an electrical connector or a USB connector.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0857144A FR2937461B1 (en) | 2008-10-21 | 2008-10-21 | CABLE AND / OR CORD FOR USE IN HOSPITAL OR IN A CONTROLLED ATMOSPHERE ENVIRONMENT AND METHOD OF MAKING THE SAME |
Publications (3)
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|---|---|
| GB0918418D0 GB0918418D0 (en) | 2009-12-09 |
| GB2464610A true GB2464610A (en) | 2010-04-28 |
| GB2464610B GB2464610B (en) | 2013-02-20 |
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| GB0918418.5A Active GB2464610B (en) | 2008-10-21 | 2009-10-21 | Cable and/or cord suitable for use in a hospital environment or in a controlled atmosphere environment and method for the manufacture thereof |
Country Status (3)
| Country | Link |
|---|---|
| DE (1) | DE102009045779B4 (en) |
| FR (1) | FR2937461B1 (en) |
| GB (1) | GB2464610B (en) |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103214706A (en) * | 2013-03-26 | 2013-07-24 | 安徽瑞侃电缆科技有限公司 | Urban rail transportation environment-friendly electric power cable material and preparation method thereof |
| EP2753341A4 (en) * | 2011-09-08 | 2015-03-04 | Nanox Tecnologia S A | Antimicrobial compositions and uses thereof |
| WO2015059520A1 (en) * | 2013-10-23 | 2015-04-30 | Prysmian S.P.A. | Energy cable having a crosslinked electrically insulating layer, and method for extracting crosslinking by-products therefrom |
| WO2016116779A1 (en) * | 2015-01-21 | 2016-07-28 | Prysmian S.P.A. | Accessory for high voltage direct current energy cables |
| CN109754938A (en) * | 2019-02-27 | 2019-05-14 | 武汉欣泰宇电力电子科技有限公司 | A kind of cable surface antibacterial and protective processing method |
| US10361010B2 (en) | 2015-04-22 | 2019-07-23 | Prysmian S.P.A. | Energy cable having a crosslinked electrically insulating system, and method for extracting crosslinking by-products therefrom |
| IT201900002609A1 (en) * | 2019-02-22 | 2020-08-22 | Prysmian Spa | METHOD FOR EXTRACTING CROSS-LINKING BYPRODUCTS FROM A CROSS-LINKED ELECTRICAL INSULATION SYSTEM OF A POWER CABLE AND ITS POWER CABLE. |
| US11011283B2 (en) | 2013-03-15 | 2021-05-18 | General Cable Technologies Corporation | Easy clean cable |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104194424B (en) * | 2014-09-19 | 2016-08-24 | 沈阳沃鑫源商贸有限公司 | A kind of preparation method of medical medical apparatus and instruments metal antibacterial coating |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1374830A1 (en) * | 2002-06-21 | 2004-01-02 | Kerr Corporation | Silver-containing dental composition |
| US20070116976A1 (en) * | 2005-11-23 | 2007-05-24 | Qi Tan | Nanoparticle enhanced thermoplastic dielectrics, methods of manufacture thereof, and articles comprising the same |
| EP1942375A2 (en) * | 2007-01-05 | 2008-07-09 | Samsung Electronics Co., Ltd. | Composition for forming photosensitive polymer complex and method of preparing photosensitive polymer complex containing silver nanoparticles using the composition |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8400150D0 (en) | 1984-01-05 | 1984-02-08 | Bp Chem Int Ltd | Polymer composition |
| EP0673881B1 (en) * | 1994-03-25 | 1999-06-16 | Kabushiki Kaisha Kaisui Kagaku Kenkyujo | Antimicrobial agent |
| JP2889836B2 (en) | 1995-03-16 | 1999-05-10 | 鐘紡株式会社 | Antibacterial zeolite with little discoloration action and method for producing the same |
| JPH11199732A (en) * | 1998-01-14 | 1999-07-27 | Hitachi Cable Ltd | Antibacterial polyvinyl chloride resin composition and electric wire and cable |
| JP2001296639A (en) | 2000-04-13 | 2001-10-26 | Fuji Photo Film Co Ltd | Packaging material for photographic sensitve material |
| US20060188580A1 (en) | 2005-02-03 | 2006-08-24 | Ralph Sacks | Anti-microbial granules |
| DE102005032616A1 (en) * | 2005-07-13 | 2007-01-25 | Rehau Ag + Co. | Plastics molding with improved mechanical properties has a UV-hardened coating containing a polyacrylate, an inorganic oxide filler, a polyol (mono)acrylate ester, a vinyl silane, a photoinitiator and an antimicrobial agent |
| DE102005042372B3 (en) * | 2005-09-07 | 2007-01-18 | Dräger Medical AG & Co. KG | Artificial respiration and/or anesthetic device comprises hydrophilic polymer material surface that contains silver particle and mineral filler such as zeolite, silicon dioxide, titanium dioxide, alumina, and zircon oxide |
-
2008
- 2008-10-21 FR FR0857144A patent/FR2937461B1/en active Active
-
2009
- 2009-10-16 DE DE102009045779.8A patent/DE102009045779B4/en active Active
- 2009-10-21 GB GB0918418.5A patent/GB2464610B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1374830A1 (en) * | 2002-06-21 | 2004-01-02 | Kerr Corporation | Silver-containing dental composition |
| US20070116976A1 (en) * | 2005-11-23 | 2007-05-24 | Qi Tan | Nanoparticle enhanced thermoplastic dielectrics, methods of manufacture thereof, and articles comprising the same |
| EP1942375A2 (en) * | 2007-01-05 | 2008-07-09 | Samsung Electronics Co., Ltd. | Composition for forming photosensitive polymer complex and method of preparing photosensitive polymer complex containing silver nanoparticles using the composition |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2753341A4 (en) * | 2011-09-08 | 2015-03-04 | Nanox Tecnologia S A | Antimicrobial compositions and uses thereof |
| US9686997B2 (en) | 2011-09-08 | 2017-06-27 | Nanox Technology Llc | Antimicrobial compositions and uses thereof |
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| CN103214706A (en) * | 2013-03-26 | 2013-07-24 | 安徽瑞侃电缆科技有限公司 | Urban rail transportation environment-friendly electric power cable material and preparation method thereof |
| US10325694B2 (en) | 2013-10-23 | 2019-06-18 | Prysmian S.P.A | Energy cable having a crosslinked electrically insulating layer, and method for extracting crosslinking by-products therefrom |
| WO2015059520A1 (en) * | 2013-10-23 | 2015-04-30 | Prysmian S.P.A. | Energy cable having a crosslinked electrically insulating layer, and method for extracting crosslinking by-products therefrom |
| US9991690B2 (en) | 2015-01-21 | 2018-06-05 | Prysmian S.P.A. | Accessory for high voltage direct current energy cables |
| WO2016116779A1 (en) * | 2015-01-21 | 2016-07-28 | Prysmian S.P.A. | Accessory for high voltage direct current energy cables |
| US10361010B2 (en) | 2015-04-22 | 2019-07-23 | Prysmian S.P.A. | Energy cable having a crosslinked electrically insulating system, and method for extracting crosslinking by-products therefrom |
| IT201900002609A1 (en) * | 2019-02-22 | 2020-08-22 | Prysmian Spa | METHOD FOR EXTRACTING CROSS-LINKING BYPRODUCTS FROM A CROSS-LINKED ELECTRICAL INSULATION SYSTEM OF A POWER CABLE AND ITS POWER CABLE. |
| EP3699931A1 (en) * | 2019-02-22 | 2020-08-26 | Prysmian S.p.A. | Method for extracting crosslinking by-products from a crosslinked electrically insulating system of a power cable and related power cable |
| US10930414B2 (en) | 2019-02-22 | 2021-02-23 | Prysmian S.P.A. | Method for extracting crosslinking by-products from a crosslinked electrically insulating system of a power cable and related power cable |
| CN109754938A (en) * | 2019-02-27 | 2019-05-14 | 武汉欣泰宇电力电子科技有限公司 | A kind of cable surface antibacterial and protective processing method |
| CN109754938B (en) * | 2019-02-27 | 2020-06-02 | 武汉欣泰宇电力电子科技有限公司 | Cable surface antibacterial protection treatment method |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2464610B (en) | 2013-02-20 |
| FR2937461A1 (en) | 2010-04-23 |
| DE102009045779B4 (en) | 2024-01-25 |
| FR2937461B1 (en) | 2014-02-14 |
| DE102009045779A1 (en) | 2010-05-12 |
| GB0918418D0 (en) | 2009-12-09 |
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