GB2161160B - Heterocyclic sulphinyl compounds - Google Patents

Heterocyclic sulphinyl compounds

Info

Publication number
GB2161160B
GB2161160B GB8516434A GB8516434A GB2161160B GB 2161160 B GB2161160 B GB 2161160B GB 8516434 A GB8516434 A GB 8516434A GB 8516434 A GB8516434 A GB 8516434A GB 2161160 B GB2161160 B GB 2161160B
Authority
GB
United Kingdom
Prior art keywords
heterocyclic
sulphinyl
compounds
sulphinyl compounds
heterocyclic sulphinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB8516434A
Other versions
GB2161160A (en
GB8516434D0 (en
Inventor
David Cox
Anthony Howard Ingall
John Louis Suschitzky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Ltd
Original Assignee
Fisons Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848417272A external-priority patent/GB8417272D0/en
Priority claimed from GB848417271A external-priority patent/GB8417271D0/en
Priority claimed from GB848419738A external-priority patent/GB8419738D0/en
Priority claimed from GB848424351A external-priority patent/GB8424351D0/en
Priority claimed from GB848424346A external-priority patent/GB8424346D0/en
Priority claimed from GB848424347A external-priority patent/GB8424347D0/en
Priority claimed from GB848424350A external-priority patent/GB8424350D0/en
Priority claimed from GB848430163A external-priority patent/GB8430163D0/en
Priority claimed from GB858509406A external-priority patent/GB8509406D0/en
Priority to GB8516434A priority Critical patent/GB2161160B/en
Application filed by Fisons Ltd filed Critical Fisons Ltd
Publication of GB8516434D0 publication Critical patent/GB8516434D0/en
Publication of GB2161160A publication Critical patent/GB2161160A/en
Publication of GB2161160B publication Critical patent/GB2161160B/en
Application granted granted Critical
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/74Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/21Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/04Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
    • C07D215/06Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62Benzothiazoles
    • C07D277/68Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70Sulfur atoms
    • C07D277/74Sulfur atoms substituted by carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB8516434A 1984-07-06 1985-06-28 Heterocyclic sulphinyl compounds Expired GB2161160B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8516434A GB2161160B (en) 1984-07-06 1985-06-28 Heterocyclic sulphinyl compounds

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
GB848417272A GB8417272D0 (en) 1984-07-06 1984-07-06 Biologically active nitrogen heterocycles
GB848417271A GB8417271D0 (en) 1984-07-06 1984-07-06 Biologically active nitrogen heterocycles
GB848419738A GB8419738D0 (en) 1984-08-02 1984-08-02 Nitrogen heterocycles
GB848424346A GB8424346D0 (en) 1984-09-26 1984-09-26 Nitrogen heterocycles
GB848424347A GB8424347D0 (en) 1984-09-26 1984-09-26 Nitrogen heterocycles
GB848424350A GB8424350D0 (en) 1984-09-26 1984-09-26 Nitrogen heterocycles
GB848424351A GB8424351D0 (en) 1984-09-26 1984-09-26 Nitrogen heterocycles
GB848430163A GB8430163D0 (en) 1984-11-29 1984-11-29 Biologically active nitrogen heterocycles
GB858509406A GB8509406D0 (en) 1985-04-12 1985-04-12 Nitrogen heterocycles
GB8516434A GB2161160B (en) 1984-07-06 1985-06-28 Heterocyclic sulphinyl compounds

Publications (3)

Publication Number Publication Date
GB8516434D0 GB8516434D0 (en) 1985-07-31
GB2161160A GB2161160A (en) 1986-01-08
GB2161160B true GB2161160B (en) 1989-05-24

Family

ID=27579368

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8516434A Expired GB2161160B (en) 1984-07-06 1985-06-28 Heterocyclic sulphinyl compounds

Country Status (1)

Country Link
GB (1) GB2161160B (en)

Families Citing this family (11)

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EP0204215B1 (en) * 1985-05-24 1993-08-11 G.D. Searle & Co. 2-[(1H-benzimidazol-2-ylsulfinyl)methyl]-benzenamines
KR950001015B1 (en) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 Process for preparing sulfoxide derivatives
JPS62207261A (en) * 1986-03-07 1987-09-11 Tokyo Tanabe Co Ltd Novel benzimidazole derivative
US4963566A (en) * 1986-03-28 1990-10-16 Otsuka Pharmaceutical Co., Ltd. Benzimidazolyl-sulfinyl-tetrahydroquinolines
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
WO1988002367A1 (en) * 1986-09-27 1988-04-07 Fisons Plc Compounds
GB8630080D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
AU2395095A (en) 1994-04-29 1995-11-29 G.D. Searle & Co. Method of using (h+/k+) atpase inhibitors as antiviral agents

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GB861907A (en) * 1956-05-14 1961-03-01 Kodak Ltd Improvements in dye-sensitized photographic emulsions
GB908352A (en) * 1959-08-07 1962-10-17 Ici Ltd Substituted 1:3:5-triazines
GB957842A (en) * 1961-04-26 1964-05-13 Ici Ltd New substituted phenols
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GB1114861A (en) * 1964-05-04 1968-05-22 Ciba Ltd New hydroxyphenyl-triazines and process for their manufacture
GB1152814A (en) * 1967-03-07 1969-05-21 Cassenne Lab Sa Improvements in or relating to Therapeutical Composition containing Mercapto-Benzimidazoles
GB1193661A (en) * 1965-06-18 1970-06-03 Agripat Sa New 1,2-Dithiol-3-Ones, their production and use
GB1223175A (en) * 1967-07-21 1971-02-24 Allied Chem Co-catalysts in anionic lactam polymerisation
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GB541024A (en) *
GB361917A (en) * 1930-08-22 1931-11-23 Ici Ltd New vulcanisation accelerators and the application thereof
GB377253A (en) * 1931-03-23 1932-07-25 Ici Ltd New sulphur-containing compounds and their application as vulcanisation accelerators for rubber and rubber like substances
GB410454A (en) * 1932-08-08 1934-05-17 Naugatuck Chem Co Improvements in or relating to the preparation of aromatic sulphide compounds
GB506296A (en) * 1937-05-08 1939-05-25 Wingfoot Corp Vulcanisation of rubber
GB522983A (en) * 1938-04-08 1940-07-02 Wingfoot Corp Improvements in the vulcanization of rubber
GB668952A (en) * 1949-04-07 1952-03-26 Us Rubber Co Chemical compounds and use as rubber anti-oxidants
GB855389A (en) * 1956-03-29 1960-11-30 Monsanto Chemicals Fungicidal compositions and basically substituted thiazoles for use therein
GB861907A (en) * 1956-05-14 1961-03-01 Kodak Ltd Improvements in dye-sensitized photographic emulsions
GB842995A (en) * 1956-06-22 1960-08-04 Irwin Neisler & Co Therapeutic bis-quaternary compounds
GB908352A (en) * 1959-08-07 1962-10-17 Ici Ltd Substituted 1:3:5-triazines
GB957842A (en) * 1961-04-26 1964-05-13 Ici Ltd New substituted phenols
GB979668A (en) * 1961-06-09 1965-01-06 Ciba Ltd Aromatic thiazole carboxylic acid halides and process for their manufacture
GB1019338A (en) * 1962-06-09 1966-02-02 Union Rheinische Braunkohlen Process for the preparation of thioethers
GB1049142A (en) * 1962-10-29 1966-11-23 Us Rubber Co Derivatives of pyridazine and their use in rubber compositions
GB1042639A (en) * 1963-08-01 1966-09-14 Us Rubber Co Substituted phenols
GB1114861A (en) * 1964-05-04 1968-05-22 Ciba Ltd New hydroxyphenyl-triazines and process for their manufacture
GB1044147A (en) * 1964-07-14 1966-09-28 Monsanto Chemicals Benzthiazole derivatives and herbicidal compositions containing them
GB1063879A (en) * 1964-09-25 1967-03-30 Taisho Pharmaceutical Co Ltd Benzimidazole derivatives
GB1193661A (en) * 1965-06-18 1970-06-03 Agripat Sa New 1,2-Dithiol-3-Ones, their production and use
GB1152814A (en) * 1967-03-07 1969-05-21 Cassenne Lab Sa Improvements in or relating to Therapeutical Composition containing Mercapto-Benzimidazoles
GB1223175A (en) * 1967-07-21 1971-02-24 Allied Chem Co-catalysts in anionic lactam polymerisation
GB1231931A (en) * 1968-08-21 1971-05-12
GB1234058A (en) * 1968-10-21 1971-06-03
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GB8516434D0 (en) 1985-07-31

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