GB2129427B - 15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation - Google Patents

15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation

Info

Publication number
GB2129427B
GB2129427B GB08326187A GB8326187A GB2129427B GB 2129427 B GB2129427 B GB 2129427B GB 08326187 A GB08326187 A GB 08326187A GB 8326187 A GB8326187 A GB 8326187A GB 2129427 B GB2129427 B GB 2129427B
Authority
GB
United Kingdom
Prior art keywords
didehydrocarboprostacyclins
preparation
cycloaliphatic derivatives
cycloaliphatic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08326187A
Other versions
GB2129427A (en
GB8326187D0 (en
Inventor
Nicola Mongelli
Carmelo Gandolfi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Priority to GB08326187A priority Critical patent/GB2129427B/en
Publication of GB8326187D0 publication Critical patent/GB8326187D0/en
Publication of GB2129427A publication Critical patent/GB2129427A/en
Application granted granted Critical
Publication of GB2129427B publication Critical patent/GB2129427B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
    • C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
    • C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/535—Organo-phosphoranes
    • C07F9/5352—Phosphoranes containing the structure P=C-
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/54—Quaternary phosphonium compounds
    • C07F9/5435—Cycloaliphatic phosphonium compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08326187A 1982-10-01 1983-09-30 15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation Expired GB2129427B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB08326187A GB2129427B (en) 1982-10-01 1983-09-30 15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8228143 1982-10-01
GB08326187A GB2129427B (en) 1982-10-01 1983-09-30 15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation

Publications (3)

Publication Number Publication Date
GB8326187D0 GB8326187D0 (en) 1983-11-02
GB2129427A GB2129427A (en) 1984-05-16
GB2129427B true GB2129427B (en) 1986-01-08

Family

ID=26284008

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08326187A Expired GB2129427B (en) 1982-10-01 1983-09-30 15-cycloaliphatic derivatives of 13,14-didehydrocarboprostacyclins and process for their preparation

Country Status (1)

Country Link
GB (1) GB2129427B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2192395B (en) * 1986-07-08 1990-11-14 Kotobuki Seiyaku Co Ltd Carbacyclin derivatives
DE3839155A1 (en) * 1988-11-17 1990-05-23 Schering Ag PROCESS FOR THE PREPARATION OF CARBACYCLINE DERIVATIVES BY STEREOSELECTIVE INTRODUCTION OF 5,6-DUAL BINDING
EP0431571A3 (en) * 1989-12-05 1992-01-02 Sagami Chemical Research Center Cis-bicyclo(4.3.0)non-2-ene derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1113341B (en) * 1978-03-31 1986-01-20 Ono Pharmaceutical Co ANALOGUES OF 6.9-METHANE-PGI2
DE2845770A1 (en) * 1978-10-19 1980-04-30 Schering Ag NEW PROSTACYCLINE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Also Published As

Publication number Publication date
GB2129427A (en) 1984-05-16
GB8326187D0 (en) 1983-11-02

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee