GB2111055B - N-(vinblastinoyl-23) derivative of amino acids - Google Patents

N-(vinblastinoyl-23) derivative of amino acids

Info

Publication number
GB2111055B
GB2111055B GB08234965A GB8234965A GB2111055B GB 2111055 B GB2111055 B GB 2111055B GB 08234965 A GB08234965 A GB 08234965A GB 8234965 A GB8234965 A GB 8234965A GB 2111055 B GB2111055 B GB 2111055B
Authority
GB
United Kingdom
Prior art keywords
vinblastinoyl
derivative
amino acids
acids
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08234965A
Other versions
GB2111055A (en
Inventor
Andre Benoit Leon Trouet
Kandukuri Sivaprasada Bhus Rao
Jean Alfred Alphonse J Hannart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of GB2111055A publication Critical patent/GB2111055A/en
Application granted granted Critical
Publication of GB2111055B publication Critical patent/GB2111055B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GB08234965A 1981-12-08 1982-12-08 N-(vinblastinoyl-23) derivative of amino acids Expired GB2111055B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (en) 1981-12-08 1981-12-08 N- (VINBLASTINOYL-23) DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
GB2111055A GB2111055A (en) 1983-06-29
GB2111055B true GB2111055B (en) 1985-07-10

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08234965A Expired GB2111055B (en) 1981-12-08 1982-12-08 N-(vinblastinoyl-23) derivative of amino acids

Country Status (24)

Country Link
JP (1) JPS58116491A (en)
AT (1) AT390958B (en)
AU (1) AU564951B2 (en)
BE (1) BE895262A (en)
CA (1) CA1198422A (en)
CH (1) CH655727A5 (en)
DD (1) DD205906A5 (en)
DE (1) DE3245269A1 (en)
DK (1) DK161833C (en)
ES (1) ES8401768A1 (en)
FR (1) FR2517680B1 (en)
GB (1) GB2111055B (en)
GR (1) GR77280B (en)
HU (1) HU187803B (en)
IE (1) IE55283B1 (en)
IL (1) IL67366A (en)
IT (1) IT1157126B (en)
LU (1) LU83822A1 (en)
NL (1) NL8204711A (en)
NZ (1) NZ202708A (en)
OA (1) OA07270A (en)
PT (1) PT75949B (en)
SE (1) SE452622B (en)
ZA (1) ZA828823B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124502B1 (en) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Conjugates of vinblastine and its derivatives, process for their preparation and pharmaceutical compositions containing these conjugates
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
EP0233101A1 (en) * 1986-01-13 1987-08-19 Ire-Celltarg S.A. Vinblastine derivatives and pharmaceutical compositions containing them
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (en) * 1988-02-08 1991-11-08 Ire Celltarg Sa VINCA DERIVATIVE CONJUGATES COMPRISING A DETERGENT CHAIN IN POSITION C-3
WO2014169697A1 (en) * 2013-04-19 2014-10-23 暨南大学 Vinblastine derivatives, preparation method therefor and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (en) 1973-04-02 1975-11-12 Lilly Co Eli PROCEDURES FOR PREPARING VINBLASTIN LEUROSIDINE AND LEUROCRISTINE DERIVATIVES
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (en) * 1980-06-10 1981-09-30 Omnium Chimique Sa Process for the preparation of N- (vinblastinoyl-23) derivatives of amino acids and peptides.

Also Published As

Publication number Publication date
GB2111055A (en) 1983-06-29
NZ202708A (en) 1986-01-24
DE3245269A1 (en) 1983-07-21
FR2517680B1 (en) 1990-05-25
CH655727A5 (en) 1986-05-15
DK161833B (en) 1991-08-19
FR2517680A1 (en) 1983-06-10
IL67366A0 (en) 1983-03-31
DK161833C (en) 1992-01-20
LU83822A1 (en) 1983-09-01
GR77280B (en) 1984-09-11
AU9084782A (en) 1983-06-16
PT75949B (en) 1985-10-04
IE822906L (en) 1983-06-08
AT390958B (en) 1990-07-25
SE8206981L (en) 1983-06-09
DK541882A (en) 1983-06-09
IT1157126B (en) 1987-02-11
OA07270A (en) 1984-04-30
ES517942A0 (en) 1984-01-01
HU187803B (en) 1986-02-28
ZA828823B (en) 1983-09-28
ATA444982A (en) 1990-01-15
PT75949A (en) 1983-01-01
IT8268431A0 (en) 1982-12-07
DD205906A5 (en) 1984-01-11
CA1198422A (en) 1985-12-24
SE452622B (en) 1987-12-07
ES8401768A1 (en) 1984-01-01
NL8204711A (en) 1983-07-01
IE55283B1 (en) 1990-08-01
JPS58116491A (en) 1983-07-11
IL67366A (en) 1987-01-30
AU564951B2 (en) 1987-09-03
BE895262A (en) 1983-06-07
JPH0449557B2 (en) 1992-08-11
SE8206981D0 (en) 1982-12-07

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19921208