GB2015516A - Pharmacologically active dihydropyridine derivatives - Google Patents

Pharmacologically active dihydropyridine derivatives

Info

Publication number
GB2015516A
GB2015516A GB7907727A GB7907727A GB2015516A GB 2015516 A GB2015516 A GB 2015516A GB 7907727 A GB7907727 A GB 7907727A GB 7907727 A GB7907727 A GB 7907727A GB 2015516 A GB2015516 A GB 2015516A
Authority
GB
United Kingdom
Prior art keywords
pharmacologically active
dihydropyridine derivatives
active dihydropyridine
derivatives
coronarodilating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB7907727A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INST ORGANICHESKOGO SINTEZA AK
Original Assignee
INST ORGANICHESKOGO SINTEZA AK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INST ORGANICHESKOGO SINTEZA AK filed Critical INST ORGANICHESKOGO SINTEZA AK
Publication of GB2015516A publication Critical patent/GB2015516A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The dihydropyridine derivatives have the formula: <IMAGE> in which R is a nitro group in the ortho- or meta- position. These compounds have a pronounced coronarodilating activity.
GB7907727A 1978-03-06 1979-03-05 Pharmacologically active dihydropyridine derivatives Withdrawn GB2015516A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU782587345A SU798099A1 (en) 1978-03-06 1978-03-06 1-benzyl-2,6-dimethyl-4-0- or -m-nitrophenyl-3,5-diethoxycarbonyl-1,4-dihydropyridines possessing coronarodilating activity

Publications (1)

Publication Number Publication Date
GB2015516A true GB2015516A (en) 1979-09-12

Family

ID=20752212

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7907727A Withdrawn GB2015516A (en) 1978-03-06 1979-03-05 Pharmacologically active dihydropyridine derivatives

Country Status (5)

Country Link
JP (1) JPS54138569A (en)
DE (1) DE2908738A1 (en)
FR (1) FR2419283A1 (en)
GB (1) GB2015516A (en)
SU (1) SU798099A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451654A2 (en) * 1990-04-11 1991-10-16 Bayer Ag Use of N-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0330470A3 (en) * 1988-02-24 1992-01-02 Ajinomoto Co., Inc. 1,4-dihydropyridine derivatives useful against tumour cells
US5216172A (en) * 1988-02-24 1993-06-01 Ajinomoto Co., Inc. 1,4-dihydropyridine-4-aryl-2,6-dimethyl-3,5-dicarboxylates useful as agents against drug resistant tumor cells
JPH076059U (en) * 1993-06-24 1995-01-27 貞夫 庄司 Bicycle saddle cover and storage

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1813436C3 (en) * 1968-12-07 1979-01-11 Bayer Ag, 5090 Leverkusen N-substituted 2,6-dimethyl-1,4-dihydropyridines
DE1923990C3 (en) * 1969-05-10 1978-11-23 Bayer Ag Process for the preparation of N-substituted M-dihydropyridine-S.S-dicarboxylic acid esters
DE2210672C3 (en) * 1972-03-06 1980-03-20 Bayer Ag, 5090 Leverkusen N-substituted asymmetrical 1 ^ -dihydropyridine-S ^ -dicarboxylic acid esters, process for their preparation and their use as medicaments

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451654A2 (en) * 1990-04-11 1991-10-16 Bayer Ag Use of N-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation
EP0451654A3 (en) * 1990-04-11 1992-07-08 Bayer Ag Use of n-alkylated 1,4-dihydropyridine carboxylic acid esters as drugs, new compounds and process for their preparation
US5234935A (en) * 1990-04-11 1993-08-10 Bayer Aktiengesellschaft N-alkylated 1,4-dihydropyridine-dicarboxylic acid esters

Also Published As

Publication number Publication date
JPS54138569A (en) 1979-10-27
SU798099A1 (en) 1981-01-23
DE2908738A1 (en) 1979-09-13
FR2419283A1 (en) 1979-10-05

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)