GB201321146D0 - Quinazoline compounds - Google Patents
Quinazoline compoundsInfo
- Publication number
- GB201321146D0 GB201321146D0 GBGB1321146.1A GB201321146A GB201321146D0 GB 201321146 D0 GB201321146 D0 GB 201321146D0 GB 201321146 A GB201321146 A GB 201321146A GB 201321146 D0 GB201321146 D0 GB 201321146D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- quinazoline compounds
- quinazoline
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1321146.1A GB201321146D0 (en) | 2013-11-29 | 2013-11-29 | Quinazoline compounds |
| PCT/GB2014/053537 WO2015079251A1 (en) | 2013-11-29 | 2014-11-28 | Quinazoline compounds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1321146.1A GB201321146D0 (en) | 2013-11-29 | 2013-11-29 | Quinazoline compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB201321146D0 true GB201321146D0 (en) | 2014-01-15 |
Family
ID=49979581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB1321146.1A Ceased GB201321146D0 (en) | 2013-11-29 | 2013-11-29 | Quinazoline compounds |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB201321146D0 (en) |
| WO (1) | WO2015079251A1 (en) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2571883B1 (en) | 2010-05-20 | 2015-01-07 | Array Biopharma, Inc. | Macrocyclic compounds as trk kinase inhibitors |
| US10202365B2 (en) | 2015-02-06 | 2019-02-12 | Blueprint Medicines Corporation | 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors |
| CA2992586A1 (en) | 2015-07-16 | 2017-01-19 | Array Biopharma, Inc. | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| CN105017164A (en) * | 2015-08-25 | 2015-11-04 | 佛山市赛维斯医药科技有限公司 | Tyrosine kinase inhibitor containing novel benzo quinazoline and ortho chlorine structure and application |
| MX2018004109A (en) | 2015-10-05 | 2018-09-27 | Univ Columbia | Activators of autophagic flux and phospholipase d and clearance of protein aggregates including tau and treatment of proteinopathies. |
| HRP20231681T1 (en) | 2015-11-02 | 2024-04-12 | Blueprint Medicines Corporation | Inhibitors of ret |
| WO2017161269A1 (en) | 2016-03-17 | 2017-09-21 | Blueprint Medicines Corporation | Inhibitors of ret receptor tyrosine kinases |
| LT3442535T (en) | 2016-04-15 | 2022-10-25 | Cancer Research Technology Limited | Heterocyclic compounds as ret kinase inhibitors |
| DK3442980T3 (en) | 2016-04-15 | 2021-08-30 | Cancer Research Tech Ltd | HETEROCYCLIC COMPOUNDS AS RIGHT-KINASE INHIBITORS |
| US10227329B2 (en) | 2016-07-22 | 2019-03-12 | Blueprint Medicines Corporation | Compounds useful for treating disorders related to RET |
| JP2018052878A (en) | 2016-09-29 | 2018-04-05 | 第一三共株式会社 | Pyridine compound |
| JOP20190077A1 (en) | 2016-10-10 | 2019-04-09 | Array Biopharma Inc | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| TWI704148B (en) | 2016-10-10 | 2020-09-11 | 美商亞雷生物製藥股份有限公司 | Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors |
| WO2018136663A1 (en) | 2017-01-18 | 2018-07-26 | Array Biopharma, Inc. | Ret inhibitors |
| US11168090B2 (en) | 2017-01-18 | 2021-11-09 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors |
| JOP20190213A1 (en) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | Macrocyclic compounds as ros1 kinase inhibitors |
| GB201705971D0 (en) | 2017-04-13 | 2017-05-31 | Cancer Res Tech Ltd | Inhibitor compounds |
| WO2018213329A1 (en) | 2017-05-15 | 2018-11-22 | Blueprint Medicines Corporation | Combinations of ret inhibitors and mtorc1 inhibitors and uses thereof for the treatment of cancer mediated by aberrant ret activity |
| TWI812649B (en) | 2017-10-10 | 2023-08-21 | 美商絡速藥業公司 | Formulations of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile |
| TWI791053B (en) | 2017-10-10 | 2023-02-01 | 美商亞雷生物製藥股份有限公司 | Crystalline forms of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile and pharmaceutical composition thereof |
| WO2019121143A1 (en) | 2017-12-20 | 2019-06-27 | Basf Se | Substituted cyclopropyl derivatives |
| CN111971286B (en) | 2018-01-18 | 2023-04-14 | 阿雷生物药品公司 | Substituted pyrrolo [2,3-d ] pyrimidine compounds as RET kinase inhibitors |
| WO2019143991A1 (en) | 2018-01-18 | 2019-07-25 | Array Biopharma Inc. | SUBSTITUTED PYRAZOLO[3,4-d]PYRIMIDINE COMPOUNDS AS RET KINASE INHIBITORS |
| CA3087972C (en) | 2018-01-18 | 2023-01-10 | Array Biopharma Inc. | Substituted pyrazolyl[4,3-c]pyridinecompounds as ret kinase inhibitors |
| CN108218713A (en) * | 2018-03-26 | 2018-06-29 | 福建仁宏医药化工有限公司 | A kind of method that 2,6- dimethyl -3- chloroanilines are prepared with 2,6- dimethyl nitrobenzenes |
| BR112020020273A2 (en) | 2018-04-03 | 2021-04-06 | Blueprint Medicines Corporation | RET INHIBITOR FOR USE IN CANCER TREATMENT HAVING A RET ALTERATION |
| US11964988B2 (en) | 2018-09-10 | 2024-04-23 | Array Biopharma Inc. | Fused heterocyclic compounds as RET kinase inhibitors |
| CN111499583B (en) * | 2020-05-22 | 2022-02-15 | 沈阳工业大学 | Quinazoline derivative and application thereof as antitumor drug |
| CN117321036A (en) * | 2021-04-30 | 2023-12-29 | 成都安泰康赛生物科技有限公司 | phenyl-O-quinoline, quinazoline, thienopyridine, thienopyrimidine, pyrrolopyridine, pyrrolopyrimidine compounds having anticancer activity |
| WO2024184550A1 (en) | 2023-03-09 | 2024-09-12 | Cancer Research Technology Limited | Biarylamide derivatives and their use as pkmyt1 inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9624482D0 (en) * | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| US6184225B1 (en) * | 1996-02-13 | 2001-02-06 | Zeneca Limited | Quinazoline derivatives as VEGF inhibitors |
| US20070299092A1 (en) * | 2004-05-20 | 2007-12-27 | Wyeth | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors |
| US20080199480A1 (en) * | 2004-07-22 | 2008-08-21 | Sequenom, Inc. | Methods for Identifying Risk of Type II Diabetes and Treatments Thereof |
| WO2011094628A1 (en) * | 2010-01-28 | 2011-08-04 | University Of Washington | Compositions and methods for treating toxoplasmosis. cryptosporidiosis and other apicomplexan protozoan related diseases |
-
2013
- 2013-11-29 GB GBGB1321146.1A patent/GB201321146D0/en not_active Ceased
-
2014
- 2014-11-28 WO PCT/GB2014/053537 patent/WO2015079251A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015079251A1 (en) | 2015-06-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB201321146D0 (en) | Quinazoline compounds | |
| HK1212694A1 (en) | Tetrahydropyrrolothiazine compounds | |
| GB201309085D0 (en) | Compounds | |
| GB201302927D0 (en) | Compounds | |
| GB201310542D0 (en) | Compounds | |
| GB201311951D0 (en) | Compounds | |
| GB201309508D0 (en) | Compounds | |
| GB201319363D0 (en) | Compounds | |
| GB201320636D0 (en) | Compounds | |
| GB201317619D0 (en) | Compounds | |
| HK1212695A1 (en) | Azetidinyloxyphenylpyrrolidine compounds | |
| GB201312901D0 (en) | Compounds | |
| GB201311953D0 (en) | Compounds | |
| EP3010923A4 (en) | Pyrroloquinazoline compounds | |
| EP2948457A4 (en) | Compounds | |
| GB201306794D0 (en) | Compounds | |
| GB201318461D0 (en) | Compounds | |
| GB201316014D0 (en) | Compounds | |
| GB201310460D0 (en) | Compounds | |
| GB201321147D0 (en) | Quinazoline compounds | |
| GB201322855D0 (en) | Compounds | |
| GB201322028D0 (en) | Compounds | |
| GB201321553D0 (en) | Compounds | |
| GB201321554D0 (en) | Compounds | |
| GB201321283D0 (en) | Compounds |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |