GB201004475D0 - Gene silencing - Google Patents

Gene silencing

Info

Publication number
GB201004475D0
GB201004475D0 GBGB1004475.8A GB201004475A GB201004475D0 GB 201004475 D0 GB201004475 D0 GB 201004475D0 GB 201004475 A GB201004475 A GB 201004475A GB 201004475 D0 GB201004475 D0 GB 201004475D0
Authority
GB
United Kingdom
Prior art keywords
gene silencing
silencing
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
GBGB1004475.8A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford University Innovation Ltd
Original Assignee
Oxford University Innovation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford University Innovation Ltd filed Critical Oxford University Innovation Ltd
Priority to GBGB1004475.8A priority Critical patent/GB201004475D0/en
Publication of GB201004475D0 publication Critical patent/GB201004475D0/en
Priority to PCT/GB2011/000378 priority patent/WO2011114106A2/en
Ceased legal-status Critical Current

Links

GBGB1004475.8A 2010-03-17 2010-03-17 Gene silencing Ceased GB201004475D0 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
GBGB1004475.8A GB201004475D0 (en) 2010-03-17 2010-03-17 Gene silencing
PCT/GB2011/000378 WO2011114106A2 (en) 2010-03-17 2011-03-17 Gene silencing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1004475.8A GB201004475D0 (en) 2010-03-17 2010-03-17 Gene silencing

Publications (1)

Publication Number Publication Date
GB201004475D0 true GB201004475D0 (en) 2010-05-05

Family

ID=42227891

Family Applications (1)

Application Number Title Priority Date Filing Date
GBGB1004475.8A Ceased GB201004475D0 (en) 2010-03-17 2010-03-17 Gene silencing

Country Status (2)

Country Link
GB (1) GB201004475D0 (en)
WO (1) WO2011114106A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201604505QA (en) * 2013-12-03 2016-07-28 Agency Science Tech & Res Tailed Mirtron Effectors For RNAi-Mediated Gene Silencing
DK3289080T3 (en) * 2015-04-30 2021-11-08 Univ Columbia GENERATION THERAPY FOR AUTOSOMAL DOMINANT DISEASES
WO2017087282A1 (en) * 2015-11-18 2017-05-26 Rosalind Franklin University Of Medicine And Science Antisense compounds targeting leucine-rich repeat kinase 2 (lrrk2) for the treatment of parkinsons disease
US10370667B2 (en) 2015-11-18 2019-08-06 Rosalind Franklin University Of Medicine And Science Antisense compounds targeting leucine-rich repeat kinase 2 (LRRK2) for the treatment of parkinsons disease
CA3006599A1 (en) 2016-01-05 2017-07-13 Ionis Pharmaceuticals, Inc. Methods for reducing lrrk2 expression
KR101956315B1 (en) * 2017-07-19 2019-03-08 국민대학교 산학협력단 miR494 as a biomarker for parkinson’s disease and diagnostic kit using thereof
TWI833770B (en) 2018-06-27 2024-03-01 美商Ionis製藥公司 Compounds and methods for reducing lrrk2 expression
GB201817470D0 (en) * 2018-10-26 2018-12-12 Univ Oxford Innovation Ltd Gene therapy
JP2023511434A (en) * 2020-01-24 2023-03-17 アルナイラム ファーマシューティカルズ， インコーポレイテッド Leucine-rich repeat kinase 2 (LRRK2) iRNA agent compositions and methods of use thereof
CN113999847A (en) * 2021-10-11 2022-02-01 中山大学附属第六医院 sgRNA of specific target LRRK2 gene, lentivirus transfection vector and application thereof
WO2023194586A2 (en) * 2022-04-08 2023-10-12 Secarna Pharmaceuticals Gmbh & Co. Kg Oligonucleotide for reducing the expression of leucine-rich repeat kinase 2 (lrrk2) and its use for preventing and/or treating human diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
JP3250802B2 (en) 1989-03-21 2002-01-28 バイカル・インコーポレイテッド Expression of exogenous polynucleotide sequences in vertebrates
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5283185A (en) 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
EP0632722A4 (en) 1992-03-20 1997-07-30 Baylor College Medicine A dna transporter system and method of use.
AU682308C (en) 1992-04-03 2006-08-17 Regents Of The University Of California, The Self-assembling polynucleotide delivery system
US5651981A (en) 1994-03-29 1997-07-29 Northwestern University Cationic phospholipids for transfection
US5527928A (en) 1994-09-30 1996-06-18 Nantz; Michael H. Cationic transport reagents
US20060171935A1 (en) * 2005-01-31 2006-08-03 Asa Abeliovich Protecting cell therapy for neurological disorders including Parkinson's disease

Also Published As

Publication number Publication date
WO2011114106A2 (en) 2011-09-22
WO2011114106A3 (en) 2012-01-05

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Legal Events

Date Code Title Description
AT Applications terminated before publication under section 16(1)