GB1465961A - Method of manufacturing capsules containing gaseous radio isotopes - Google Patents
Method of manufacturing capsules containing gaseous radio isotopesInfo
- Publication number
- GB1465961A GB1465961A GB2085574A GB2085574A GB1465961A GB 1465961 A GB1465961 A GB 1465961A GB 2085574 A GB2085574 A GB 2085574A GB 2085574 A GB2085574 A GB 2085574A GB 1465961 A GB1465961 A GB 1465961A
- Authority
- GB
- United Kingdom
- Prior art keywords
- valve
- diluent
- radioisotope
- chamber
- container
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002775 capsule Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000003085 diluting agent Substances 0.000 abstract 6
- 239000003708 ampul Substances 0.000 abstract 3
- 239000007789 gas Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000011521 glass Substances 0.000 abstract 1
- 238000009991 scouring Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1262—Capsules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S53/00—Package making
- Y10S53/90—Capsules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus For Radiation Diagnosis (AREA)
Abstract
1465961 Mixing gases GENERAL ELECTRIC CO 10 May 1974 [15 Aug 1973] 20855/ 74 Heading B1C [Also in Division F4] Mixing of a gaseous radioisotope released by crushing a glass ampoule in a chamber 14 with a gaseous diluent from container 33 prior to supplying the mixture to apparatus for manufacturing gas capsules (see Div. F4), comprises the following steps: a) Evacuating lines 12, 21 by pump 30 with valves 15, 19, 22, 28 open; b) closing valves 15, 19, 22, 28 and then crushing the ampoule in chamber 14 to release the radioisotope; c) opening valves 32, 22 to admit diluent from container 33 as far as closed valve 19, such supply being terminated when a desired pressure measured by gauge 20 is reached; d) opening and closing valve 19 to admit diluent to chamber 14 before opening valve 15 and screwing down piston 17 to expel the radioisotope and diluent to mixing container 11, the valve 15 being then closed; e) repeating step (d) until the required amount of diluent is present in the mixing zone between container 11 and valve 19; and f) opening valve 15 whilst valve 19 is closed and reciprocating piston 13 to cause mixing of the radioisotope and diluent by scouring the mixture back and forth between chamber 14 and vessel 11. Instead of crushing an ampoule, the radioisotope may be supplied to chamber 14 from a storage container (Fig. 2, not shown).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US388488A US3893278A (en) | 1973-08-15 | 1973-08-15 | Method of manufacturing capsules containing gaseous radioisotope |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1465961A true GB1465961A (en) | 1977-03-02 |
Family
ID=23534316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2085574A Expired GB1465961A (en) | 1973-08-15 | 1974-05-10 | Method of manufacturing capsules containing gaseous radio isotopes |
Country Status (11)
Country | Link |
---|---|
US (1) | US3893278A (en) |
JP (1) | JPS5072479A (en) |
BE (1) | BE818776A (en) |
CH (1) | CH573748A5 (en) |
DE (1) | DE2434277A1 (en) |
DK (2) | DK134388B (en) |
FR (1) | FR2245336B1 (en) |
GB (1) | GB1465961A (en) |
IT (1) | IT1019936B (en) |
NL (1) | NL7407235A (en) |
SE (1) | SE409075B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6286319B1 (en) * | 1998-09-30 | 2001-09-11 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6523356B2 (en) | 1998-09-30 | 2003-02-25 | Medi-Physics, Inc. | Meted hyperpolarized noble gas dispensing methods and associated devices |
US6237363B1 (en) | 1998-09-30 | 2001-05-29 | Medi-Physics, Inc. | Hyperpolarized noble gas extraction methods masking methods and associated transport containers |
CN100437001C (en) * | 2005-05-13 | 2008-11-26 | 鸿富锦精密工业(深圳)有限公司 | Vacuum liquid filling device and vacuum liquid filling method |
US8069886B1 (en) | 2006-06-02 | 2011-12-06 | Vulcan Lead, Inc. | Capsule preparation system |
JP5033147B2 (en) * | 2009-02-04 | 2012-09-26 | 株式会社 ノサカテック | Container lid joining method |
BR112014008204B1 (en) | 2011-10-06 | 2020-07-28 | Combocap, Inc | method and apparatus for making a capsule to retain a substance |
US9456987B2 (en) | 2013-04-03 | 2016-10-04 | Binutra, Inc. | Capsule with internal diaphragm |
CA3103406A1 (en) * | 2018-06-14 | 2019-12-19 | Curium Us Llc | Evacuation/fill station for radioactive fluid container production |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3040490A (en) * | 1960-05-31 | 1962-06-26 | Triangle Package Machinery Co | Apparatus and method for making, filling, and sealing containers |
DE1642089A1 (en) * | 1965-03-27 | 1971-05-06 | Metrimpex Magyar Mueszeripari | Method and device for the automatic production of liquid pharmaceutical preparations filled into ampoules |
-
1973
- 1973-08-15 US US388488A patent/US3893278A/en not_active Expired - Lifetime
-
1974
- 1974-05-07 DK DK249574AA patent/DK134388B/en unknown
- 1974-05-07 DK DK29574*#A patent/DK29574A/da unknown
- 1974-05-10 GB GB2085574A patent/GB1465961A/en not_active Expired
- 1974-05-29 NL NL7407235A patent/NL7407235A/en not_active Application Discontinuation
- 1974-07-17 DE DE2434277A patent/DE2434277A1/en not_active Withdrawn
- 1974-08-09 CH CH1091674A patent/CH573748A5/xx not_active IP Right Cessation
- 1974-08-12 FR FR7427942A patent/FR2245336B1/fr not_active Expired
- 1974-08-13 BE BE147543A patent/BE818776A/en unknown
- 1974-08-14 IT IT26304/74A patent/IT1019936B/en active
- 1974-08-14 SE SE7410389A patent/SE409075B/en unknown
- 1974-08-14 JP JP49092430A patent/JPS5072479A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IT1019936B (en) | 1977-11-30 |
SE409075B (en) | 1979-07-30 |
SE7410389L (en) | 1975-02-17 |
FR2245336A1 (en) | 1975-04-25 |
FR2245336B1 (en) | 1978-04-28 |
CH573748A5 (en) | 1976-03-31 |
DE2434277A1 (en) | 1975-02-27 |
DK134388B (en) | 1976-11-01 |
AU6851874A (en) | 1975-11-06 |
US3893278A (en) | 1975-07-08 |
JPS5072479A (en) | 1975-06-16 |
DK134388C (en) | 1977-05-09 |
NL7407235A (en) | 1975-02-18 |
BE818776A (en) | 1975-02-13 |
DK29574A (en) | 1975-04-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |