GB1440842A - Immunological adjuvants and process for their preparation - Google Patents

Immunological adjuvants and process for their preparation

Info

Publication number
GB1440842A
GB1440842A GB2914973A GB2914973A GB1440842A GB 1440842 A GB1440842 A GB 1440842A GB 2914973 A GB2914973 A GB 2914973A GB 2914973 A GB2914973 A GB 2914973A GB 1440842 A GB1440842 A GB 1440842A
Authority
GB
United Kingdom
Prior art keywords
cells
june
strain
immunological adjuvants
immunological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2914973A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bpifrance Financement SA
Original Assignee
Agence National de Valorisation de la Recherche ANVAR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7141610A external-priority patent/FR2160326B1/fr
Priority claimed from GB5499371A external-priority patent/GB1426042A/en
Priority claimed from FR7222120A external-priority patent/FR2189019A2/en
Application filed by Agence National de Valorisation de la Recherche ANVAR filed Critical Agence National de Valorisation de la Recherche ANVAR
Publication of GB1440842A publication Critical patent/GB1440842A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

1440842 Immunological adjuvants AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE 19 June 1973 [19 June 1972 16 Nov 1972] 29149/73 Addition to 1426042 Heading A5B A process for preparing a water-soluble agent, having activity as an immunological adjuvant, especially for vaccines, comprises cultivating a strain of mycobacteria or Nocardia cells; recovering the cells of the cultivated strain; treating the cells with solvents so as to cause delipidation thereof and subjecting the delipidated whole cells to the action of a murolytic enzyme, the solid fraction being subsequently removed and the aqueous fraction containing the agent recovered. The agents may be treated with a proteolytic enzyme such as trypsin to remove amino acid impurities.
GB2914973A 1971-11-19 1973-06-19 Immunological adjuvants and process for their preparation Expired GB1440842A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR7141610A FR2160326B1 (en) 1971-11-19 1971-11-19
GB5499371A GB1426042A (en) 1971-11-26 1971-11-26 water-soluble immunological adjuvants
FR7222120A FR2189019A2 (en) 1971-11-19 1972-06-19 Water-soluble immunological adjuvant - consisting of an oligomer of microbial cell wall components

Publications (1)

Publication Number Publication Date
GB1440842A true GB1440842A (en) 1976-06-30

Family

ID=27249702

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2914973A Expired GB1440842A (en) 1971-11-19 1973-06-19 Immunological adjuvants and process for their preparation

Country Status (1)

Country Link
GB (1) GB1440842A (en)

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee