GB1395929A - Thioureas - Google Patents

Thioureas

Info

Publication number
GB1395929A
GB1395929A GB3701572A GB3701572A GB1395929A GB 1395929 A GB1395929 A GB 1395929A GB 3701572 A GB3701572 A GB 3701572A GB 3701572 A GB3701572 A GB 3701572A GB 1395929 A GB1395929 A GB 1395929A
Authority
GB
United Kingdom
Prior art keywords
alkyl
thioureas
salts
compounds
alkylthioalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3701572A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB635271A priority Critical patent/GB1338169A/en
Priority to CA134,517A priority patent/CA949967A/en
Priority to FR7207170A priority patent/FR2128505B1/fr
Priority to CH553475A priority patent/CH578583A5/xx
Priority to CH338172A priority patent/CH576478A5/xx
Priority to CH553575A priority patent/CH578584A5/xx
Priority to NL7203145.A priority patent/NL162073C/en
Priority to DE19722211454 priority patent/DE2211454B2/en
Priority to DE2265369A priority patent/DE2265369C3/en
Priority to GB3701572A priority patent/GB1395929A/en
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Priority to US450937A priority patent/US3905984A/en
Priority to US05/450,931 priority patent/US3932427A/en
Priority to US05/451,333 priority patent/US3950353A/en
Priority to US05/450,957 priority patent/US3950333A/en
Priority to JP49147491A priority patent/JPS5243833B2/ja
Priority to JP49147490A priority patent/JPS5243832B2/ja
Publication of GB1395929A publication Critical patent/GB1395929A/en
Priority to US05/586,670 priority patent/US4027026A/en
Priority to US05/626,682 priority patent/US4018928A/en
Priority to US05/637,496 priority patent/US4022797A/en
Priority to US05/637,494 priority patent/US4018931A/en
Priority to US05/637,499 priority patent/US4024271A/en
Priority to US05/638,005 priority patent/US4053473A/en
Priority to US05/667,738 priority patent/US4049672A/en
Priority to US05/758,291 priority patent/US4069327A/en
Priority to US05/764,921 priority patent/US4137237A/en
Priority to US05/805,491 priority patent/US4137234A/en
Priority to US05/837,961 priority patent/US4151288A/en
Priority to US05/847,285 priority patent/US4154844A/en
Priority to US05/940,547 priority patent/US4230865A/en
Priority to US05/948,358 priority patent/US4228291A/en
Priority to US06/003,160 priority patent/US4226874A/en
Priority to US06/126,809 priority patent/US4287198A/en
Priority to US06/130,760 priority patent/US4307101A/en
Priority to US06/138,637 priority patent/US4293697A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

1395929 Isoxazolyl- and isothiazolyl-alkylthioalkyl - thioureas SMITH KLINE & FRENCH LABORATORIES Ltd 26 July 1973 [8 Aug 1972] 37015/72 Addition to 1338169 Heading C2C Novel compounds (I) (including salts thereof) where M is O or S, R 4 is H, C 1 to C 4 alkyl, halogen, NH 2 or OH and R 5 is H or C 1 to C 4 alkyl, are made by standard methods from the corresponding -CH 2 S(CH 2 ) 2 NH 2 compounds or salts thereof. Pharmaceutical preparations useful in inhibiting histamine and gastrin actions contain (I) as active ingredient. Administration is orally, parenterally or topically.
GB3701572A 1971-03-09 1972-08-08 Thioureas Expired GB1395929A (en)

Priority Applications (34)

Application Number Priority Date Filing Date Title
GB635271A GB1338169A (en) 1971-03-09 1971-03-09 Ureas thioureas and guanidines
CA134,517A CA949967A (en) 1971-03-09 1972-02-11 Pharmacologically active compounds
FR7207170A FR2128505B1 (en) 1971-03-09 1972-03-02
CH338172A CH576478A5 (en) 1971-03-09 1972-03-08
CH553575A CH578584A5 (en) 1971-03-09 1972-03-08
CH553475A CH578583A5 (en) 1971-03-09 1972-03-08
DE19722211454 DE2211454B2 (en) 1971-03-09 1972-03-09 HETEROCYCLIC UREA, THIOURA AND GUANIDINE DERIVATIVES, THEIR SALT WITH ACIDS AND THEIR USE AS HISTAMINE H LOW 2 - RECEPTOR ANTAGONISTS
NL7203145.A NL162073C (en) 1971-03-09 1972-03-09 METHOD FOR PREPARING MEDICINAL PRODUCTS WITH HISTAMINE RECEPTOR BLOCKING ACTIVITY, SO PREPARED MEDICINAL PRODUCTS, AND PREPARATION OF SUITABLE COMPOUNDS.
DE2265369A DE2265369C3 (en) 1971-03-09 1972-03-09 Heterocyclic aminoethers and thioethers and their salts with acids
GB3701572A GB1395929A (en) 1972-08-08 1972-08-08 Thioureas
US450937A US3905984A (en) 1971-03-09 1974-03-13 Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas
US05/450,931 US3932427A (en) 1971-03-09 1974-03-13 Pyridyl substituted aminoalkyl-thioureas and ureas
US05/451,333 US3950353A (en) 1971-03-09 1974-03-14 Pharmacologically active thiourea and urea compounds
US05/450,957 US3950333A (en) 1971-03-09 1974-03-14 Pharmacologically active guanidine compounds
JP49147491A JPS5243833B2 (en) 1971-03-09 1974-12-20
JP49147490A JPS5243832B2 (en) 1971-03-09 1974-12-20
US05/586,670 US4027026A (en) 1971-03-09 1975-06-13 Pharmaceutical compositions and methods of inhibiting H-2 histamine receptors with pyridyl substituted thioalkyl- and oxyalkyl-thioureas and ureas
US05/626,682 US4018928A (en) 1971-03-09 1975-10-29 Pyridyl substituted aminoalkyl-thioureas and ureas
US05/637,496 US4022797A (en) 1971-03-09 1975-12-04 Certain thiazole, isothiazole, oxazole, and isoxazole compounds
US05/637,499 US4024271A (en) 1971-03-09 1975-12-04 Pharmacologically active guanidine compounds
US05/637,494 US4018931A (en) 1971-03-09 1975-12-04 Pharmacologically active thiourea and urea compounds
US05/638,005 US4053473A (en) 1971-07-22 1975-12-05 Pharmacologically active thiourea and urea compounds
US05/667,738 US4049672A (en) 1971-03-09 1976-03-17 4-Methyl-5-imidazolylmethylthioethylamine and -S-methylisothiourea
US05/758,291 US4069327A (en) 1971-03-09 1977-01-05 Pharmacologically active thiourea and urea compounds as inhibitors of H-2 histamine receptors
US05/764,921 US4137237A (en) 1971-03-09 1977-02-02 Pharmacologically active guanidine compounds
US05/805,491 US4137234A (en) 1971-03-09 1977-06-10 Thiazole, isothiazole, oxazole and isoxazole substituted thiourea and urea compounds
US05/837,961 US4151288A (en) 1971-03-09 1977-09-29 Pharmacologically active thiourea and urea compounds
US05/847,285 US4154844A (en) 1971-03-09 1977-10-31 Pharmacologically active guanidine compounds in compositions and methods of use
US05/940,547 US4230865A (en) 1971-03-09 1978-09-08 Pharmacologically active triazole and thiadiazole thiourea and urea compounds
US05/948,358 US4228291A (en) 1971-03-09 1978-10-04 Pharmacologically active thiadiazole guanidine compounds
US06/003,160 US4226874A (en) 1971-03-09 1979-01-15 Pharmacologically active thiourea and urea compositions and methods of use
US06/126,809 US4287198A (en) 1971-03-09 1980-03-03 Pharmacologically active guanidine compounds
US06/130,760 US4307101A (en) 1971-03-09 1980-03-17 Inhibitors of H-2 histamine receptors
US06/138,637 US4293697A (en) 1971-03-09 1980-04-09 Pharmacologically active thiourea and urea compounds

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3701572A GB1395929A (en) 1972-08-08 1972-08-08 Thioureas

Publications (1)

Publication Number Publication Date
GB1395929A true GB1395929A (en) 1975-05-29

Family

ID=10393034

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3701572A Expired GB1395929A (en) 1971-03-09 1972-08-08 Thioureas

Country Status (1)

Country Link
GB (1) GB1395929A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4165377A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
US4165377A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidino imidazoles and thiazoles
US4234735A (en) 1977-04-20 1980-11-18 Imperial Chemical Industries Limited Guanidino imidazoles and thiazoles
US4262126A (en) 1977-04-20 1981-04-14 Imperial Chemical Industries Limited Guanidine derivatives of imidazoles and thiazoles

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Legal Events

Date Code Title Description
PS Patent sealed
746B Proceeding under section 46(3) patents act 1977