GB1363659A - Tetralones and indanones - Google Patents

Tetralones and indanones

Info

Publication number
GB1363659A
GB1363659A GB3538973A GB3538973A GB1363659A GB 1363659 A GB1363659 A GB 1363659A GB 3538973 A GB3538973 A GB 3538973A GB 3538973 A GB3538973 A GB 3538973A GB 1363659 A GB1363659 A GB 1363659A
Authority
GB
United Kingdom
Prior art keywords
halogen
phso
alkylsulphonyl
alkyl
tetrahydropyranyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3538973A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Publication of GB1363659A publication Critical patent/GB1363659A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1363659 Ketones AMERICAN HOME PRODUCTS CORP 1 Dec 1971 [3 Dec 1970 21 May 1971] 35389/73 Divided out of 1363658 Heading C2C Compounds of the general formula (R<SP>8</SP> = H, C 1-4 alkyl or alkoxy, acyloxy, Ph(C 1-4 alkoxy), halogen, CF 3 ; R<SP>9</SP>=alkoxycarbonyl, C 1-4 alkyl, C 3-5 alkenyl, Ph(C 1-4 alkyl); Y<SP>1</SP>= halogen, C 1-4 alkylsulphonyl, PhSO 2 , tetrahydropyranyloxy; Ph = phenyl, optionally substituted ; m = 0, 1; n =2-6) are prepared by reacting a compound of the formula with Z(CH 2 ) n Y<SP>1</SP> (Z=halogen, C 1-4 alkylsulphonyl, PhSO 2 ), optionally followed by hydrolysis when Y<SP>1</SP> = tetrahydropyranyloxy and conversion of the resulting alcohol to a product in which Y<SP>1</SP>=halogen, C 1-4 alkylsulphonyl or PhSO 2 . The preparation of 1-ethoxycarbonyl-2-indanone is described, and 1-(3-bromopropyl)-1- methyl-2-tetralone is characterized as the 2,4- dinitrophenylhydrazone.
GB3538973A 1970-12-03 1971-12-01 Tetralones and indanones Expired GB1363659A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9498370A 1970-12-03 1970-12-03

Publications (1)

Publication Number Publication Date
GB1363659A true GB1363659A (en) 1974-08-14

Family

ID=22248330

Family Applications (3)

Application Number Title Priority Date Filing Date
GB5571771A Expired GB1363658A (en) 1970-12-03 1971-12-01 Benzobicycloalkane compounds
GB3539073A Expired GB1363660A (en) 1970-12-03 1971-12-01 Benzobicycloalkane compounds
GB3538973A Expired GB1363659A (en) 1970-12-03 1971-12-01 Tetralones and indanones

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB5571771A Expired GB1363658A (en) 1970-12-03 1971-12-01 Benzobicycloalkane compounds
GB3539073A Expired GB1363660A (en) 1970-12-03 1971-12-01 Benzobicycloalkane compounds

Country Status (21)

Country Link
JP (1) JPS5747176B1 (en)
AR (5) AR193714A1 (en)
AT (2) AT325597B (en)
AU (1) AU475974B2 (en)
BE (1) BE776173A (en)
CA (1) CA1005822A (en)
CH (1) CH569689A5 (en)
CY (1) CY922A (en)
DE (1) DE2159324C2 (en)
DK (1) DK142984C (en)
ES (1) ES397603A1 (en)
FI (1) FI53967C (en)
FR (1) FR2116509B1 (en)
GB (3) GB1363658A (en)
HK (1) HK12678A (en)
KE (1) KE2770A (en)
NL (1) NL175292C (en)
PH (1) PH13159A (en)
SE (1) SE385471B (en)
YU (1) YU35866B (en)
ZA (1) ZA717697B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1504694A (en) * 1974-04-08 1978-03-22 Akzo Nv Benzo-bicyclononene derivatives
GB1549172A (en) * 1975-04-29 1979-08-01 Akzonv Benzobicyclononene derivatives
US5098916A (en) * 1990-03-29 1992-03-24 G. D. Searle & Co. Propanobicyclic amine derivatives for cns disorders
JP6605157B2 (en) * 2016-01-04 2019-11-13 山東丹紅制薬有限公司 Analogs of dezocine
JP2022519086A (en) * 2019-02-02 2022-03-18 ヤンツェー リバー ファーマシューティカル グループ カンパニー リミテッド Dezocin derivatives and their medical uses
CN110283085A (en) * 2019-06-04 2019-09-27 华润双鹤利民药业(济南)有限公司 A kind of dezocine fabrication processing
CN113979875B (en) * 2020-07-27 2022-11-08 扬子江药业集团有限公司 Dezocine derivative crystal form A and preparation method and application thereof

Also Published As

Publication number Publication date
FI53967C (en) 1978-09-11
GB1363660A (en) 1974-08-14
HK12678A (en) 1978-03-17
DK142984C (en) 1981-09-28
CH569689A5 (en) 1975-11-28
JPS5747176B1 (en) 1982-10-07
KE2770A (en) 1977-10-21
AT321265B (en) 1975-03-25
DE2159324C2 (en) 1984-06-14
AR194020A1 (en) 1973-06-12
YU35866B (en) 1981-08-31
AU3624871A (en) 1973-06-07
DK142984B (en) 1981-03-09
AT325597B (en) 1975-10-27
SE385471B (en) 1976-07-05
AR197202A1 (en) 1974-03-22
AR198637A1 (en) 1974-07-15
NL7116567A (en) 1972-06-06
YU302271A (en) 1981-02-28
PH13159A (en) 1980-01-08
NL175292C (en) 1984-10-16
ATA10874A (en) 1975-01-15
CA1005822A (en) 1977-02-22
NL175292B (en) 1984-05-16
ES397603A1 (en) 1975-03-16
FR2116509B1 (en) 1975-08-01
AR193903A1 (en) 1973-05-31
FI53967B (en) 1978-05-31
FR2116509A1 (en) 1972-07-13
BE776173A (en) 1972-06-02
GB1363658A (en) 1974-08-14
AR193714A1 (en) 1973-05-22
AU475974B2 (en) 1976-09-09
CY922A (en) 1977-12-23
ZA717697B (en) 1973-06-27
DE2159324A1 (en) 1972-06-15

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Legal Events

Date Code Title Description
PS Patent sealed
PE20 Patent expired after termination of 20 years