GB1235957A - Alkaloid derivative - Google Patents

Alkaloid derivative

Info

Publication number
GB1235957A
GB1235957A GB49126/69A GB4912669A GB1235957A GB 1235957 A GB1235957 A GB 1235957A GB 49126/69 A GB49126/69 A GB 49126/69A GB 4912669 A GB4912669 A GB 4912669A GB 1235957 A GB1235957 A GB 1235957A
Authority
GB
United Kingdom
Prior art keywords
alkaloid
alkaloid derivative
compounds
eisai
alkenyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB49126/69A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of GB1235957A publication Critical patent/GB1235957A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B42—BOOKBINDING; ALBUMS; FILES; SPECIAL PRINTED MATTER
    • B42D—BOOKS; BOOK COVERS; LOOSE LEAVES; PRINTED MATTER CHARACTERISED BY IDENTIFICATION OR SECURITY FEATURES; PRINTED MATTER OF SPECIAL FORMAT OR STYLE NOT OTHERWISE PROVIDED FOR; DEVICES FOR USE THEREWITH AND NOT OTHERWISE PROVIDED FOR; MOVABLE-STRIP WRITING OR READING APPARATUS
    • B42D17/00—Hanging or securing devices for books, newspapers or the like

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

1,235,957. Alkaloid derivatives. EISAI K.K. 7 Oct., 1969 [18 Feb., 1969], No. 49126/69. Heading C2C. Novel compounds I in which R is 1-4 C alkyl or alkenyl and X is Br are prepared by reaction of the alkaloid with the appropriate p-alkoxy or p-alkenyloxy benzyl halide. Pharmaceutical compositions comprise a compound I together with a suitable carrier and are administered orally or parenterally. Compounds I have strong parasympathetic blocking activity.
GB49126/69A 1969-02-18 1969-10-07 Alkaloid derivative Expired GB1235957A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1153169 1969-02-18

Publications (1)

Publication Number Publication Date
GB1235957A true GB1235957A (en) 1971-06-16

Family

ID=11780535

Family Applications (1)

Application Number Title Priority Date Filing Date
GB49126/69A Expired GB1235957A (en) 1969-02-18 1969-10-07 Alkaloid derivative

Country Status (7)

Country Link
US (1) US3696110A (en)
CH (1) CH510030A (en)
DE (1) DE1950378C2 (en)
FR (1) FR2034553B1 (en)
GB (1) GB1235957A (en)
NL (1) NL142674B (en)
SE (1) SE351848B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5470430A (en) * 1977-11-16 1979-06-06 Eisai Co Ltd Remedy for bradyacusia and tinnitus
US20050226920A1 (en) * 2004-04-13 2005-10-13 Kirk Voelker Method of decreasing nicotine withdrawal symptoms during smoking cessation.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1062704B (en) * 1956-08-07 1959-08-06 Licencia Talalmanyokat Process for the production of quaternary atropines
DE1163845B (en) * 1960-10-18 1964-02-27 Egyesult G>ogyszer es Tapszer g>ar Budipest λ ertr Dr C W I otter hos und Dr Ing FI W Lotterhos Pat Anwalte Frankfurt"^ Process for the preparation of p-alkylbenzyl-tropinium derivatives.
AT246339B (en) * 1960-10-18 1966-04-12 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of new p-alkylbenzyltropinium derivatives
DE1165037B (en) * 1961-11-21 1964-03-12 Dr. Schwarz Arzneimittelfabrik G.m.b.H., Monheim (RhId.) Process for the preparation of esters of quaternary atropinium salts.
FR1539224A (en) * 1966-09-02 1968-09-13 Boehringer Sohn Ingelheim Process for making tropic acid derivatives

Also Published As

Publication number Publication date
DE1950378C2 (en) 1985-10-03
FR2034553B1 (en) 1974-02-01
DE1950378A1 (en) 1970-08-27
SE351848B (en) 1972-12-11
US3696110A (en) 1972-10-03
FR2034553A1 (en) 1970-12-11
NL142674B (en) 1974-07-15
NL7001733A (en) 1970-08-20
CH510030A (en) 1971-07-15

Similar Documents

Publication Publication Date Title
GB1147379A (en) 4-alkyl-dialkoxy-ª‡-methylphenethylamines and pharmacologically acceptable salts
GB1374979A (en) 3,5-dioxopiperazine derivatives
GB1301973A (en)
GB1367785A (en) 2-substituted adenosine derivatives and the production thereof
GB1439724A (en) Berbine derivatives and pharmaceutical compositions containing them
GB1268951A (en) Phenoxy-amines
GB1235957A (en) Alkaloid derivative
ES426664A1 (en) 2-Substituted phenyl-s-triazolo[5,1-a] isoquinoline compounds
GB1261147A (en) Pentanedione derivatives
GB1256723A (en)
GB1184044A (en) Nitrofuryl-Oxadiazole Derivatives
GB1325770A (en) Pyrimidopyridazine derivatives
GB1291442A (en) Adamantylamino-5,8-dihydronaphthyloxy-propanols and related compounds
GB1246117A (en) Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture
GB1283632A (en) Phenylethanolamine derivatives
GB1178012A (en) A Method for the Production of Pyridine Derivatives
GB1299421A (en) 3-substituted amino-6-hydrazino-pyridazines
GB1302353A (en)
GB1181520A (en) Substituted 1-Aminoadamantanes
GB1132397A (en) Improvements in or relating to fluorene derivatives and the manufacture thereof
GB1173309A (en) The Manufacture of Benzdiaz[1,4]Epine Derivatives
GB1373271A (en) Indoles
IE33346L (en) Cyclohexa - 1, 4 - diene - 1 acetic acid.
GB1332635A (en) Rutin complexes
GB1346456A (en) Organic acid 2,6-disubstituted phenyl hydrazides