GB1146867A - Noved des-a-gonanes, and processes for their preparation - Google Patents

Noved des-a-gonanes, and processes for their preparation

Info

Publication number
GB1146867A
GB1146867A GB5710266A GB5710266A GB1146867A GB 1146867 A GB1146867 A GB 1146867A GB 5710266 A GB5710266 A GB 5710266A GB 5710266 A GB5710266 A GB 5710266A GB 1146867 A GB1146867 A GB 1146867A
Authority
GB
United Kingdom
Prior art keywords
des
gona
gonanes
hydroxymethylene
gon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5710266A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of GB1146867A publication Critical patent/GB1146867A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J73/00Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/003Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by oxygen as hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,146,867. Des A-gonanes. ROUSSELUCLAF. 21 Dec., 1966 [23 Dec., 1965], No. 57102/66. Heading C2C. Novel compounds having the formulµ where R represents an alkyl radical, and X represents a hydrogen atom, a saturated or unsaturated aliphatic hydrocarbon radical optionally containing an oxygen atom in the hydrocarbon chain, or an acyl group derived from an organic carboxylic acid are obtained by reacting a des-A-gon-9-en-5-one with a formylating agent to give a 10-hydroxymethylene - des - A - gon - 9(11) - en - 5 - one, reacting the latter with a dehydrogenating agent to form a 10-formyl-des-A-gona-9,11- dien-5-one, and selectively reducing the latter to form a 10-hydroxymethyl-des-A-gona-9,11- dien-5-one. Alternatively the 10-hydroxymethylene starting compound is obtained by condensing a 5-enamino-des-A-gona-5(10), 9(11)- diene with formylacetic mixed anhydride to give the corresponding iminium compound which is subjected to acid hydrolysis.
GB5710266A 1965-12-23 1966-12-21 Noved des-a-gonanes, and processes for their preparation Expired GB1146867A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR43565A FR1476631A (en) 1965-12-23 1965-12-23 New substituted tricyclic compounds and method of preparation

Publications (1)

Publication Number Publication Date
GB1146867A true GB1146867A (en) 1969-03-26

Family

ID=8596668

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5710266A Expired GB1146867A (en) 1965-12-23 1966-12-21 Noved des-a-gonanes, and processes for their preparation

Country Status (12)

Country Link
JP (1) JPS4935618B1 (en)
AT (1) AT267775B (en)
BE (1) BE691403A (en)
CH (1) CH467738A (en)
DE (1) DE1593349A1 (en)
DK (1) DK135710B (en)
ES (1) ES334801A1 (en)
FR (1) FR1476631A (en)
GB (1) GB1146867A (en)
IL (2) IL27130A (en)
NL (2) NL6618080A (en)
SE (1) SE317969B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526642A (en) * 1968-06-19 1970-09-01 Squibb & Sons Inc 2-oxa-5beta-cyanopregnane derivatives

Also Published As

Publication number Publication date
ES334801A1 (en) 1968-03-01
SE317969B (en) 1969-12-01
NL6618080A (en) 1967-06-26
IL27130A (en) 1971-07-28
AT267775B (en) 1969-01-10
JPS4935618B1 (en) 1974-09-25
DK135710B (en) 1977-06-13
IL35912A (en) 1971-07-28
NL128001C (en)
BE691403A (en) 1967-06-19
DK135710C (en) 1977-12-27
DE1593349A1 (en) 1970-07-23
CH467738A (en) 1969-01-31
FR1476631A (en) 1967-04-14

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