GB1036272A - Tertiary aryloxyalkanoyl aminoalkylamines - Google Patents

Tertiary aryloxyalkanoyl aminoalkylamines

Info

Publication number
GB1036272A
GB1036272A GB3763665A GB3763665A GB1036272A GB 1036272 A GB1036272 A GB 1036272A GB 3763665 A GB3763665 A GB 3763665A GB 3763665 A GB3763665 A GB 3763665A GB 1036272 A GB1036272 A GB 1036272A
Authority
GB
United Kingdom
Prior art keywords
aminoalkylamines
aryloxyalkanoyl
tertiary
compounds
appropriate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3763665A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandsche Combinatie voor Chemische Industrie NV
Original Assignee
Nederlandsche Combinatie voor Chemische Industrie NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandsche Combinatie voor Chemische Industrie NV filed Critical Nederlandsche Combinatie voor Chemische Industrie NV
Priority to GB3763665A priority Critical patent/GB1036272A/en
Publication of GB1036272A publication Critical patent/GB1036272A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention comprises compounds of <FORM:1036272/C2/1> wherein Ar is a phenyl group optionally substituted by a methylenedioxy group, one or two C1- 4 alkyl groups or halogen atoms of which at most one is in the ortho-position with respect to the aminoalkylaminoalkoxy residue, or one or two C1- 4 alkoxy, nitro or trifluoromethyl groups, R1 is a hydrogen atom or a C1- 4 alkyl group, and n is 0, 1 or 2, acid addition salts thereof, and their preparation by reaction of the appropriate aryloxyacetyl chloride with the appropriate amine. The compounds of the invention have anti-tussive activity. Reference has been directed by the Comptroller to Specification 942,761.
GB3763665A 1961-11-20 1961-11-20 Tertiary aryloxyalkanoyl aminoalkylamines Expired GB1036272A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB3763665A GB1036272A (en) 1961-11-20 1961-11-20 Tertiary aryloxyalkanoyl aminoalkylamines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB3763665A GB1036272A (en) 1961-11-20 1961-11-20 Tertiary aryloxyalkanoyl aminoalkylamines

Publications (1)

Publication Number Publication Date
GB1036272A true GB1036272A (en) 1966-07-20

Family

ID=10397881

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3763665A Expired GB1036272A (en) 1961-11-20 1961-11-20 Tertiary aryloxyalkanoyl aminoalkylamines

Country Status (1)

Country Link
GB (1) GB1036272A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760035A (en) * 1993-09-22 1998-06-02 Knoll Aktiengesellschaft Therapeutic agents

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760035A (en) * 1993-09-22 1998-06-02 Knoll Aktiengesellschaft Therapeutic agents

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