FR2761071B1 - DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION - Google Patents

DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2761071B1
FR2761071B1 FR9703387A FR9703387A FR2761071B1 FR 2761071 B1 FR2761071 B1 FR 2761071B1 FR 9703387 A FR9703387 A FR 9703387A FR 9703387 A FR9703387 A FR 9703387A FR 2761071 B1 FR2761071 B1 FR 2761071B1
Authority
FR
France
Prior art keywords
dihydroquinolein
quinolein
derivatives
preparation
therapeutic application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9703387A
Other languages
French (fr)
Other versions
FR2761071A1 (en
Inventor
Gary Mccort
Christian Hoornaert
Caroline Cadilhac
Olivier Duclos
Eric Guilpain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9703387A priority Critical patent/FR2761071B1/en
Priority to EP98914928A priority patent/EP0971928A1/en
Priority to AU69239/98A priority patent/AU6923998A/en
Priority to PCT/FR1998/000528 priority patent/WO1998042712A1/en
Priority to ARP980101209A priority patent/AR012094A1/en
Priority to ZA982362A priority patent/ZA982362B/en
Publication of FR2761071A1 publication Critical patent/FR2761071A1/en
Application granted granted Critical
Publication of FR2761071B1 publication Critical patent/FR2761071B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9703387A 1997-03-20 1997-03-20 DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Expired - Fee Related FR2761071B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9703387A FR2761071B1 (en) 1997-03-20 1997-03-20 DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP98914928A EP0971928A1 (en) 1997-03-20 1998-03-17 Quinoline-2(1h)-one and dihydroquinoline-2(1h)-one derivatives as ligands of 5-ht, 5-ht2 and 5-ht1-like receptors
AU69239/98A AU6923998A (en) 1997-03-20 1998-03-17 Quinoline-2(1h)-one and dihydroquinoline-2(1h)-one derivatives as ligands of 5-ht, 5-ht2 and 5-ht1-like receptors
PCT/FR1998/000528 WO1998042712A1 (en) 1997-03-20 1998-03-17 Quinoline-2(1h)-one and dihydroquinoline-2(1h)-one derivatives as ligands of 5-ht, 5-ht2 and 5-ht1-like receptors
ARP980101209A AR012094A1 (en) 1997-03-20 1998-03-18 DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) -ONE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS.
ZA982362A ZA982362B (en) 1997-03-20 1998-03-19 Quinolin-2-(1h)-one and dihydroquinolin-2-(1h)-one derivatives their preparation and their therapeutic application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9703387A FR2761071B1 (en) 1997-03-20 1997-03-20 DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
FR2761071A1 FR2761071A1 (en) 1998-09-25
FR2761071B1 true FR2761071B1 (en) 1999-12-03

Family

ID=9504998

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9703387A Expired - Fee Related FR2761071B1 (en) 1997-03-20 1997-03-20 DERIVATIVES OF QUINOLEIN-2 (1H) -ONE AND DIHYDROQUINOLEIN-2 (1H) - ONE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Country Status (6)

Country Link
EP (1) EP0971928A1 (en)
AR (1) AR012094A1 (en)
AU (1) AU6923998A (en)
FR (1) FR2761071B1 (en)
WO (1) WO1998042712A1 (en)
ZA (1) ZA982362B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110929A (en) * 1998-07-28 2000-08-29 3M Innovative Properties Company Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof
FR2797874B1 (en) * 1999-08-27 2002-03-29 Adir NOVEL PYRIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
MY127093A (en) † 2000-05-17 2006-11-30 Lucite Int Uk Ltd Bidentate ligands useful in catalyst systems
CA2448729A1 (en) * 2000-11-20 2002-05-23 Biovitrum Ab Piperazinyl and piperidyl substituted heterocyclic compounds
SE0004245D0 (en) 2000-11-20 2000-11-20 Pharmacia Ab Novel compounds and their use
US7160888B2 (en) 2003-08-22 2007-01-09 Warner Lambert Company Llc [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia
JP4596792B2 (en) * 2004-02-24 2010-12-15 あすか製薬株式会社 Drugs having both 5-HT1A agonistic action and 5-HT3 antagonistic action
WO2008037681A1 (en) * 2006-09-26 2008-04-03 Glaxo Group Limited 5-{2-[4-(2-methyl-5-quinolinyl)-l-piperidinyl] ethyl} quinolinone derivatives as 5ht1a receptor modulators for treating sexual dysfunction, cognition impairement, psychotic disorders, anxiety, depression, etc.
US9893294B2 (en) 2010-11-22 2018-02-13 The Regents Of The University Of California Organic small molecule semiconducting chromophores for use in organic electronic devices
MA41168A (en) * 2014-12-17 2017-10-24 Acraf NEW ANTIBACTERIAL COMPOUNDS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1278792C (en) * 1985-05-06 1991-01-08 Joseph P. Yevich Antipsychotic fused-ring pyridinylpiperazine derivatives
FR2637591B1 (en) * 1988-10-11 1992-10-23 Synthelabo QUINOLEINONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2738823B1 (en) * 1995-09-15 1997-10-31 Synthelabo DERIVATIVES OF 3- (OMEGA- (4- (THIENO (3,2-C) PYRIDIN-4-YL) PIPERAZIN- 1-YL) ALKYL) -3,4-DIHYDROQUINOLEIN-2 (1H) -ONE, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS
EP0850235B1 (en) * 1995-09-15 1999-12-01 Sanofi-Synthelabo Quinolein-2(1h)-one derivatives as serotonin antagonists

Also Published As

Publication number Publication date
AR012094A1 (en) 2000-09-27
ZA982362B (en) 1998-09-23
EP0971928A1 (en) 2000-01-19
AU6923998A (en) 1998-10-20
WO1998042712A1 (en) 1998-10-01
FR2761071A1 (en) 1998-09-25

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