FR2665901B2 - NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS. - Google Patents

NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS.

Info

Publication number
FR2665901B2
FR2665901B2 FR9010323A FR9010323A FR2665901B2 FR 2665901 B2 FR2665901 B2 FR 2665901B2 FR 9010323 A FR9010323 A FR 9010323A FR 9010323 A FR9010323 A FR 9010323A FR 2665901 B2 FR2665901 B2 FR 2665901B2
Authority
FR
France
Prior art keywords
sterouides
11beta
medicaments
preparation
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9010323A
Other languages
French (fr)
Other versions
FR2665901A2 (en
Inventor
Roussel-Uclaf Socie Directoire
Conseil De Surveillance
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8902384A external-priority patent/FR2643638B1/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR9010323A priority Critical patent/FR2665901B2/en
Priority to DK91402214T priority patent/DK0471612T3/en
Priority to DE69128820T priority patent/DE69128820T2/en
Priority to EP91402214A priority patent/EP0471612B1/en
Priority to AT91402214T priority patent/ATE162797T1/en
Priority to ES91402214T priority patent/ES2112268T3/en
Priority to KR1019910013914A priority patent/KR920004408A/en
Priority to MX9100647A priority patent/MX9100647A/en
Priority to HU912690A priority patent/HUT59416A/en
Priority to IE286391A priority patent/IE912863A1/en
Priority to CA002049102A priority patent/CA2049102A1/en
Priority to JP03226410A priority patent/JP3073803B2/en
Priority to AU82422/91A priority patent/AU644671B2/en
Priority to ZA916420A priority patent/ZA916420B/en
Priority to PT98681A priority patent/PT98681B/en
Publication of FR2665901A2 publication Critical patent/FR2665901A2/en
Priority to US08/068,735 priority patent/US5707982A/en
Publication of FR2665901B2 publication Critical patent/FR2665901B2/en
Application granted granted Critical
Priority to US08/442,957 priority patent/US6790971B1/en
Priority to GR970402371T priority patent/GR3026315T3/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR9010323A 1989-02-24 1990-08-14 NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS. Expired - Lifetime FR2665901B2 (en)

Priority Applications (18)

Application Number Priority Date Filing Date Title
FR9010323A FR2665901B2 (en) 1989-02-24 1990-08-14 NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS.
DK91402214T DK0471612T3 (en) 1990-08-14 1991-08-09 New 19-nor carbon chain steroids comprising an amide group at the 11-beta position, process for their preparation, the
DE69128820T DE69128820T2 (en) 1990-08-14 1991-08-09 New 19-nor steroids that have an amide-bearing group in the 11-beta site, their manufacture, their use as medicines and pharmaceutical preparations thereof
EP91402214A EP0471612B1 (en) 1990-08-14 1991-08-09 New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof
AT91402214T ATE162797T1 (en) 1990-08-14 1991-08-09 NEW 19-NOR STEROIDS HAVING AN AMIDE-PORTING GROUP IN THE 11-BETA SITE, THEIR PRODUCTION, THEIR USE AS MEDICATIONS AND PHARMACEUTICAL PREPARATIONS THEREOF
ES91402214T ES2112268T3 (en) 1990-08-14 1991-08-09 NEW 19-NOR-STEROIDS THAT HAVE IN POSITION 11BETA A CARBON CHAIN THAT INCLUDES AN AMIDA FUNCTION, ITS PREPARATION, ITS APPLICATION AS DRUGS AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
IE286391A IE912863A1 (en) 1990-08-14 1991-08-13 New 19-nor steroids having a carbonated chain containing an¹amide function in position 11beta, their preparation, their¹use as medicaments and the pharmaceutical compositions¹containing them
JP03226410A JP3073803B2 (en) 1990-08-14 1991-08-13 Novel 19-nor steroids having a carbon chain containing an amide function at the 11β position, their preparation, their use as medicaments and pharmaceutical compositions containing them
MX9100647A MX9100647A (en) 1990-08-14 1991-08-13 NEW 19-NOR-STEROIDS THAT HAVE IN POSITION II BETA A CARBON CHAIN THAT CONTAINS AN AMIDA FUNCTION, ITS PREPARATION, ITS APPLICATION AS MEDICINES AND THE PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
HU912690A HUT59416A (en) 1990-08-14 1991-08-13 Process for producing new 19-norsteroid derivatives carrying carbon chain comprising amido group in 11beta position and pharmaceutical compositions comprising same
KR1019910013914A KR920004408A (en) 1990-08-14 1991-08-13 Novel 19-norsteroid having a carbonized chain containing an amide functional group at the 11 beta position, a process for its preparation, its use as a medicament and a pharmaceutical composition containing the same
CA002049102A CA2049102A1 (en) 1990-08-14 1991-08-13 19-nor-steroids with a carbon chain in 11-beta containing an amido group, preparation thereof, their application as drugs and pharmaceutical compositions containing them
AU82422/91A AU644671B2 (en) 1990-08-14 1991-08-14 New 19-NOR steroids having a carbonated chain containing an amide function in position 11beta, their preparation, their use as medicaments and the pharmaceutical compositions containing them
ZA916420A ZA916420B (en) 1990-08-14 1991-08-14 19-nor steroids having a carbonated chain containing an amide function in position 11 beta,their preparation,their use as medicaments and the pharmaceutical compositions containing them
PT98681A PT98681B (en) 1990-08-14 1991-08-14 METHOD FOR PREPARING NEW 19-NOR STEROIDS WHICH HAVE IN A POSITION 11B A CHAIN OF CARBON ATOMES WITH A FUNCTION AMIDA AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM
US08/068,735 US5707982A (en) 1989-02-24 1993-05-28 19-nor-steroids
US08/442,957 US6790971B1 (en) 1989-02-24 1995-05-17 19-Nor-steroids
GR970402371T GR3026315T3 (en) 1990-08-14 1998-03-11 New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8902384A FR2643638B1 (en) 1989-02-24 1989-02-24 NOVEL 19-NOR STEROIDS HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE OR CARBAMATE FUNCTION, THEIR PREPARATION METHOD AND INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR9010323A FR2665901B2 (en) 1989-02-24 1990-08-14 NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS.

Publications (2)

Publication Number Publication Date
FR2665901A2 FR2665901A2 (en) 1992-02-21
FR2665901B2 true FR2665901B2 (en) 1994-07-29

Family

ID=26227181

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9010323A Expired - Lifetime FR2665901B2 (en) 1989-02-24 1990-08-14 NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS.

Country Status (1)

Country Link
FR (1) FR2665901B2 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235949B1 (en) * 1973-06-18 1978-03-17 Roussel Uclaf
FR2522328B1 (en) * 1982-03-01 1986-02-14 Roussel Uclaf NEW PRODUCTS DERIVED FROM THE STRUCTURE 3-CETO 4,9 19-NOR STEROIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
GB8513723D0 (en) * 1985-05-31 1985-07-03 Erba Farmitalia 11-beta substituted steroids
DE3621024C2 (en) * 1986-06-20 1999-10-28 Schering Ag 11beta-phenylestradienes, their preparation and pharmaceutical preparations containing them
FR2620707B1 (en) * 1987-09-18 1989-12-08 Roussel Uclaf NOVEL STEROIDS COMPRISING A 3, 4 OR 6-CHAIN SPIRANIC CYCLE IN POSITION 17, THEIR PROCESS AND PREPARATION INTERMEDIATES, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Also Published As

Publication number Publication date
FR2665901A2 (en) 1992-02-21

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