FR2619110B1 - ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION - Google Patents

((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Info

Publication number
FR2619110B1
FR2619110B1 FR8711288A FR8711288A FR2619110B1 FR 2619110 B1 FR2619110 B1 FR 2619110B1 FR 8711288 A FR8711288 A FR 8711288A FR 8711288 A FR8711288 A FR 8711288A FR 2619110 B1 FR2619110 B1 FR 2619110B1
Authority
FR
France
Prior art keywords
isoquinoleine
piperidinyl
tetrahydro
derivatives
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8711288A
Other languages
French (fr)
Other versions
FR2619110A1 (en
Inventor
Pascal George
Mireille Sevrin
Christian Maloizel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8711288A priority Critical patent/FR2619110B1/en
Priority to FR8718342A priority patent/FR2625504B2/en
Priority to FR8805130A priority patent/FR2630114B2/en
Priority to FR8805129A priority patent/FR2630113B2/en
Priority to FR8809447A priority patent/FR2634204B2/en
Priority to FR8809448A priority patent/FR2634205B2/en
Priority to EP88402022A priority patent/EP0306375A1/en
Priority to IL87339A priority patent/IL87339A0/en
Priority to US07/228,748 priority patent/US4885302A/en
Priority to KR1019880010015A priority patent/KR890003733A/en
Priority to DK437588A priority patent/DK437588A/en
Priority to FI883667A priority patent/FI883667A/en
Priority to ZA885786A priority patent/ZA885786B/en
Priority to HU884106A priority patent/HU199451B/en
Priority to JP63197010A priority patent/JPH01100167A/en
Priority to NZ225708A priority patent/NZ225708A/en
Priority to AU20475/88A priority patent/AU598149B2/en
Priority to NO88883485A priority patent/NO883485L/en
Priority to PT8820488A priority patent/PT88204A/en
Publication of FR2619110A1 publication Critical patent/FR2619110A1/en
Priority to US07/400,811 priority patent/US4945096A/en
Application granted granted Critical
Publication of FR2619110B1 publication Critical patent/FR2619110B1/en
Priority to CS914051A priority patent/CZ405191A3/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8711288A 1987-08-07 1987-08-07 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION Expired FR2619110B1 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR8711288A FR2619110B1 (en) 1987-08-07 1987-08-07 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8718342A FR2625504B2 (en) 1987-08-07 1987-12-30 ((BENZOYL-1 PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8805130A FR2630114B2 (en) 1987-08-07 1988-04-19 (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8805129A FR2630113B2 (en) 1987-08-07 1988-04-19 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8809447A FR2634204B2 (en) 1987-08-07 1988-07-12 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINS DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR8809448A FR2634205B2 (en) 1987-08-07 1988-07-12 ME THYL-4 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP88402022A EP0306375A1 (en) 1987-08-07 1988-08-03 2-[(4-Piperidinyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their use in therapy
IL87339A IL87339A0 (en) 1987-08-07 1988-08-04 2-((4-piperidyl)methyl)-1,2,3-4-tetrahydroisoquinoline derivatives,their preparation and their application in therapy
NO88883485A NO883485L (en) 1987-08-07 1988-08-05 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PIPERIDINYL-ISOKINOLINE COMPOUNDS.
DK437588A DK437588A (en) 1987-08-07 1988-08-05 DERIVATIVES OF 2 - ((4-PIPERIDINYL) METHYL) -1,2,3,4-TETRAHYDROISOQUINOLINE FOR THERAPEUTIC USE AND PROCEDURE FOR THE PREPARATION OF SUCH DERIVATIVES
US07/228,748 US4885302A (en) 1987-08-07 1988-08-05 2-((4-Piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy
ZA885786A ZA885786B (en) 1987-08-07 1988-08-05 2-(4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives,their preparations and their application in therapy
HU884106A HU199451B (en) 1987-08-07 1988-08-05 Process for producing 2-square brackets open /piperidin-4-yl/-methyl square brackets closed-1,2,3,4-tetrahydroisoquinoline derivatives and pharmaceutical compositions comprising same
JP63197010A JPH01100167A (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4- tetrahydroisoquinoline derivative
NZ225708A NZ225708A (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives
AU20475/88A AU598149B2 (en) 1987-08-07 1988-08-05 2-((4-piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy
KR1019880010015A KR890003733A (en) 1987-08-07 1988-08-05 2-[(4-piperidyl) methyl] -1,2,3,4-tetrahydro isoquinoline derivative, its use in preparation and treatment
PT8820488A PT88204A (en) 1987-08-07 1988-08-05 New 2-piperidinyl:methyl-1,2,3,4-tetra:hydro-isoquinoline derivs. - with selective action on HT one A serotoninergic receptors, e.g. for treating depression and cardiovascular disease
FI883667A FI883667A (en) 1987-08-07 1988-08-05 2 - / (4-PIPERIDINYL) METHYL / -1,2,3,4-TETRAHYDROISOKINOLINE DERIVATIVES, DERAS FRAMSTAELLNING OCH TERAPEUTISKA ANVAENDNING.
US07/400,811 US4945096A (en) 1987-08-07 1989-08-30 Treatment of a depressive state with 2-[(4-piperidyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivates
CS914051A CZ405191A3 (en) 1987-08-07 1991-12-23 derivatives of 2-|(piperidinyl-4)methyl¨-1,2,3,4-tetrahydroisoquinoline, process of their preparation and pharmaceutical compositions in which said derivatives are comprised

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8711288A FR2619110B1 (en) 1987-08-07 1987-08-07 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
FR2619110A1 FR2619110A1 (en) 1989-02-10
FR2619110B1 true FR2619110B1 (en) 1989-11-17

Family

ID=9354026

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8711288A Expired FR2619110B1 (en) 1987-08-07 1987-08-07 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Country Status (2)

Country Link
FR (1) FR2619110B1 (en)
ZA (1) ZA885786B (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670041A1 (en) * 1967-03-14 1972-03-02 American Home Prod Isoindoles and isoindolines
FR7607M (en) * 1968-04-25 1970-01-19

Also Published As

Publication number Publication date
ZA885786B (en) 1989-04-26
FR2619110A1 (en) 1989-02-10

Similar Documents

Publication Publication Date Title
FR2601368B1 (en) NITROFURAN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2587029B1 (en) BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2667317B1 (en) 2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2681325B1 (en) DERIVATIVES OF AMINOMETHYL-4 PIPERIDINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2618149B1 (en) N-AMINOALKYL N-PHENYL ARYLAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2580281B1 (en) NITROFURAN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2634207B1 (en) ((PIPERIDINYL-4) METHYL) BENZAZEPINES DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2638747B1 (en) PHENYLOXYPROPANOLAMINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2654106B1 (en) PHOSPHORUS DERIVATIVES OF CYTOSINE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2581646B1 (en) IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2516509B1 (en) BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2668152B1 (en) N, O SPIROCYCLIC DERIVATIVES OF CYCLOTRIPHOSPHAZENES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2606409B1 (en) IMIDAZOPYRIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2619110B1 (en) ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2634204B2 (en) ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINS DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2630114B2 (en) (PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2630113B2 (en) ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2638745B1 (en) ((N-ALKYLTHIOALKYL-METHYLAMINO) -2 ETHYL) -5 BENZOTHIAZEPINE-1,5 ONE-4 DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2604434B1 (en) 2-AMINO ETHANETHIOL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2625504B2 (en) ((BENZOYL-1 PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2634205B2 (en) ME THYL-4 ((PIPERIDINYL-4) METHYL) -2 TETRAHYDRO-1,2,3,4 ISOQUINOLEIN DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2571722B1 (en) BENZIMIDAZOLONE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2621584B1 (en) BENZOTHIAZEPINE-1,5 DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2637595B1 (en) BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2618151B1 (en) PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Legal Events

Date Code Title Description
ST Notification of lapse