FR2537980B1 - Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation - Google Patents

Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation

Info

Publication number
FR2537980B1
FR2537980B1 FR8319976A FR8319976A FR2537980B1 FR 2537980 B1 FR2537980 B1 FR 2537980B1 FR 8319976 A FR8319976 A FR 8319976A FR 8319976 A FR8319976 A FR 8319976A FR 2537980 B1 FR2537980 B1 FR 2537980B1
Authority
FR
France
Prior art keywords
preparation
acid derivatives
hydroxycarboxylic acid
oligomeric hydroxycarboxylic
oligomeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8319976A
Other languages
English (en)
Other versions
FR2537980A1 (fr
Inventor
Joachim Franz
Walter Prikoszovich
Zdenek Brich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH737382A external-priority patent/CH651475A5/de
Priority claimed from CH737282A external-priority patent/CH660488A5/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2537980A1 publication Critical patent/FR2537980A1/fr
Application granted granted Critical
Publication of FR2537980B1 publication Critical patent/FR2537980B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR8319976A 1982-12-17 1983-12-12 Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation Expired FR2537980B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH737382A CH651475A5 (en) 1982-12-17 1982-12-17 Pharmaceutical composition for delayed release of the active substance under physiological conditions
CH737282A CH660488A5 (en) 1982-12-17 1982-12-17 (Co)oligomeric hydroxycarboxylic acid derivatives, the preparation thereof, and the use thereof in pharmaceutical compositions

Publications (2)

Publication Number Publication Date
FR2537980A1 FR2537980A1 (fr) 1984-06-22
FR2537980B1 true FR2537980B1 (fr) 1986-12-19

Family

ID=25701206

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8319976A Expired FR2537980B1 (fr) 1982-12-17 1983-12-12 Derives d'acides hydroxycarboxyliques oligomeres, leur preparation et leur utilisation

Country Status (7)

Country Link
US (1) US4801739A (fr)
CY (2) CY1529A (fr)
DE (1) DE3345314A1 (fr)
FR (1) FR2537980B1 (fr)
GB (4) GB2135320B (fr)
HK (1) HK27290A (fr)
IT (1) IT1197759B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8514090D0 (en) * 1985-06-04 1985-07-10 Sandoz Ltd Organic compounds
US4663309A (en) * 1983-06-29 1987-05-05 University Patents, Inc. Novel peptide hormones with calcitonin-like activity
CH656884A5 (de) * 1983-08-26 1986-07-31 Sandoz Ag Polyolester, deren herstellung und verwendung.
DE3720806C2 (de) * 1986-07-03 1997-08-21 Clariant Finance Bvi Ltd Verwendung eines Stabilisators in Peroxydbleichverfahren
FR2654337B1 (fr) * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
US5629173A (en) * 1990-08-09 1997-05-13 Genentech, Inc. Methods of use of serine protease variants having peptide ligase activity
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
WO1992011843A1 (fr) * 1991-01-09 1992-07-23 Alza Corporation Dispositifs bioerodables et compositions pour liberer par diffusion des agents actifs
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
DE4224401A1 (de) * 1992-07-21 1994-01-27 Pharmatech Gmbh Neue biologisch abbaubare Polymere für die Arzneistoffgalenik
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
US5543158A (en) * 1993-07-23 1996-08-06 Massachusetts Institute Of Technology Biodegradable injectable nanoparticles
US5565215A (en) * 1993-07-23 1996-10-15 Massachusettes Institute Of Technology Biodegradable injectable particles for imaging
ATE178789T1 (de) * 1994-02-21 1999-04-15 Takeda Chemical Industries Ltd Polyester matrix für eine pharmazeutische zusammensetzung mit verzögerter freigabe
US6007845A (en) * 1994-07-22 1999-12-28 Massachusetts Institute Of Technology Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
AU706541B2 (en) * 1995-06-09 1999-06-17 Euro-Celtique S.A. Formulations and methods for providing prolonged local anesthesia
JP3301311B2 (ja) * 1996-05-24 2002-07-15 株式会社神戸製鋼所 ２−ヒドロキシカルボン酸オリゴマーの連続製造方法
EP0954301A4 (fr) 1996-06-24 2006-03-08 Euro Celtique Sa Methodes sures d'anesthesie locale
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5900266A (en) * 1997-05-29 1999-05-04 The Curators Of The University Of Missouri Heat-treated lactic and/or glycolic acid compositions and methods of use
US6326042B1 (en) 1997-05-29 2001-12-04 The Curators Of The University Of Missouri Antimicrobial use of heat-treated lactic and/or glycolic acid compositions for treatment of ground meats
IL129951A0 (en) 1997-07-02 2000-02-29 Euro Celtique Sa Prolonged anesthesia in joints and body spaces
DE60118575T3 (de) * 2000-08-07 2011-05-19 Takeda Pharmaceutical Co. Ltd. Milchsäurepolymer und verfahren zu dessen herstellung
JP2004521111A (ja) * 2001-01-25 2004-07-15 ユーロ−セルティーク，エス．エイ． 局所麻酔薬および使用法
TWI332407B (en) 2001-06-29 2010-11-01 Takeda Chemical Industries Ltd Controlled release composition and method of producting the same
WO2005007122A2 (fr) 2003-07-18 2005-01-27 Oakwood Laboratories, L.L.C. Prevention de reduction de poids moleculaire du polymere, de formation d'impuretes et de gelification dans des compositions polymeres
DK1787658T3 (da) 2005-11-10 2012-06-25 Chemi Spa Formuleringer med forsinket frigørelse og indeholdende somatostatin-analoge væksthormoninhibitorer
ES2791698T3 (es) 2006-12-18 2020-11-05 Takeda Pharmaceuticals Co Composición de liberación sostenida y método para producir la misma

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2362511A (en) * 1939-11-21 1944-11-14 Du Pont Modified glycolide resins
DE936746C (de) * 1953-05-01 1955-12-22 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung von Lactylmilchsaeureamiden
US3141030A (en) * 1961-12-28 1964-07-14 Paniplus Company Acyl lactylic acid compositions and methods of preparation thereof
US3440241A (en) * 1966-05-31 1969-04-22 Syntex Corp Preparation of 6-keto-14alpha-hydroxy-delta**7-dehydro steroids
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4011312A (en) * 1975-06-25 1977-03-08 American Home Products Corporation Prolonged release drug form for the treatment of bovine mastitis
US4010196A (en) * 1975-06-25 1977-03-01 American Home Products Corporation Linear polyester salts
US4273920A (en) * 1979-09-12 1981-06-16 Eli Lilly And Company Polymerization process and product
US4384975A (en) * 1980-06-13 1983-05-24 Sandoz, Inc. Process for preparation of microspheres
PH19942A (en) * 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions

Also Published As

Publication number Publication date
GB2135320B (en) 1987-04-29
HK27290A (en) 1990-04-20
CY1530A (en) 1990-11-16
GB2166652B (en) 1987-03-11
IT8349520A0 (it) 1983-12-16
GB2165454A (en) 1986-04-16
GB2135320A (en) 1984-08-30
IT1197759B (it) 1988-12-06
GB2165454B (en) 1987-03-11
GB8333289D0 (en) 1984-01-18
GB8527419D0 (en) 1985-12-11
GB2165849A (en) 1986-04-23
CY1529A (en) 1990-11-16
GB8527420D0 (en) 1985-12-11
US4801739A (en) 1989-01-31
DE3345314A1 (de) 1984-07-05
GB8527421D0 (en) 1985-12-11
FR2537980A1 (fr) 1984-06-22
GB2166652A (en) 1986-05-14

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Legal Events

Date Code Title Description
ST Notification of lapse