FR2531857B1 - Composition injectable pour prolonger la stabilite et la retention de particules enrobees, injectees dans le flux sanguin d'animaux et d'etres humains - Google Patents

Composition injectable pour prolonger la stabilite et la retention de particules enrobees, injectees dans le flux sanguin d'animaux et d'etres humains

Info

Publication number
FR2531857B1
FR2531857B1 FR8312439A FR8312439A FR2531857B1 FR 2531857 B1 FR2531857 B1 FR 2531857B1 FR 8312439 A FR8312439 A FR 8312439A FR 8312439 A FR8312439 A FR 8312439A FR 2531857 B1 FR2531857 B1 FR 2531857B1
Authority
FR
France
Prior art keywords
prolonging
animals
retention
stability
blood flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8312439A
Other languages
English (en)
Other versions
FR2531857A1 (fr
Inventor
Henry A Sloviter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Publication of FR2531857A1 publication Critical patent/FR2531857A1/fr
Application granted granted Critical
Publication of FR2531857B1 publication Critical patent/FR2531857B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender

Landscapes

  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8312439A 1982-07-27 1983-07-27 Composition injectable pour prolonger la stabilite et la retention de particules enrobees, injectees dans le flux sanguin d'animaux et d'etres humains Expired FR2531857B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/402,449 US4397870A (en) 1982-07-27 1982-07-27 Process for prolonging retention of emulsion particles in the bloodstream

Publications (2)

Publication Number Publication Date
FR2531857A1 FR2531857A1 (fr) 1984-02-24
FR2531857B1 true FR2531857B1 (fr) 1986-04-11

Family

ID=23591925

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8312439A Expired FR2531857B1 (fr) 1982-07-27 1983-07-27 Composition injectable pour prolonger la stabilite et la retention de particules enrobees, injectees dans le flux sanguin d'animaux et d'etres humains

Country Status (6)

Country Link
US (1) US4397870A (fr)
CA (1) CA1201655A (fr)
DE (1) DE3326900A1 (fr)
FR (1) FR2531857B1 (fr)
GB (1) GB2124079B (fr)
SE (1) SE8304144L (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924132B2 (ja) * 1980-12-02 1984-06-07 株式会社 林原生物化学研究所 栄養補給用乳剤の製法
US4770874A (en) * 1983-08-22 1988-09-13 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4933179A (en) * 1983-08-22 1990-06-12 Syntex (U.S.A.) Inc. Feline leukemia virus antigen vaccines
US4772466A (en) * 1983-08-22 1988-09-20 Syntex (U.S.A.) Inc. Vaccines comprising polyoxypropylene-polyoxyethylene block polymer based adjuvants
US4606918A (en) * 1983-08-22 1986-08-19 Syntex (U.S.A.) Inc. Polyoxypropylene-polyoxyethylene block polymer based adjuvants
GB8407557D0 (en) * 1984-03-23 1984-05-02 Hayward J A Polymeric lipsomes
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US5077036A (en) * 1986-01-14 1991-12-31 Alliance Pharmaceutical Corp. Biocompatible stable fluorocarbon emulsions for contrast enhancement and oxygen transport comprising 40-125% wt./volume fluorocarbon combined with a phospholipid
US4987154A (en) * 1986-01-14 1991-01-22 Alliance Pharmaceutical Corp. Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use
US4927623A (en) * 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
US5080885A (en) * 1986-01-14 1992-01-14 Alliance Pharmaceutical Corp. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
DE3700911C2 (de) * 1986-01-17 2001-05-17 West Pharm Serv Drug Res Ltd System zur Zuführung eines Arzneimittels oder eines Diagnostikums
US5514720A (en) * 1986-07-09 1996-05-07 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
US5684050A (en) * 1986-01-24 1997-11-04 Hemagen/Pfc Stable emulsions of highly fluorinated organic compounds
ES2044933T3 (es) * 1986-08-07 1994-01-16 Minnesota Mining & Mfg Emulsiones de productos quimicos fluorados, biologicamente activas y estables.
US4895876A (en) * 1987-03-20 1990-01-23 Air Products And Chemicals, Inc. Concentrated stable fluorochemical aqueous emulsions containing triglycerides
US4866096A (en) * 1987-03-20 1989-09-12 Air Products And Chemicals, Inc. Stable fluorochemical aqueous emulsions
US4956390A (en) * 1987-08-25 1990-09-11 Air Products And Chemicals, Inc. Gas transport employing perfluorobutyldecalin
EP0318081B1 (fr) * 1987-11-27 1991-07-24 Akzo N.V. Stabilisation d'anticorps
US5061484A (en) * 1988-03-11 1991-10-29 Alpha Therapeutic Corporation Perfluorochemical emulsion with stabilized vesicles
US5171755A (en) * 1988-04-29 1992-12-15 Hemagen/Pfc Emulsions of highly fluorinated organic compounds
US5114703A (en) * 1989-05-30 1992-05-19 Alliance Pharmaceutical Corp. Percutaneous lymphography using particulate fluorocarbon emulsions
AU647372B2 (en) * 1989-07-05 1994-03-24 Alliance Pharmaceutical Corporation Fluorocarbon emulsions having saturated phospholipid emulsifiers
US5146014A (en) * 1991-07-02 1992-09-08 Air Products And Chemicals, Inc. Perfluoroethyldimethyl cyclohexane
US5403575A (en) * 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
US5350359A (en) * 1992-07-16 1994-09-27 Temple University Of The Commonwealth System Of Higher Education Control, treatment and/or diagnosis of physiological conditions with degassed perfluorocarbon liquid
DE4308312A1 (de) * 1993-03-16 1994-09-22 Fresenius Ag Kardioplegische Emulsion
US6679859B1 (en) 1997-10-24 2004-01-20 Alliance Pharmaceutical Corp. Amelioration of ischemic damage using synthetic oxygen carriers
US8192845B2 (en) * 2005-11-04 2012-06-05 Cargill, Incorported Lecithin-containing starch compositions, preparation thereof and paper products having oil and grease resistance, and/or release properties
US7931778B2 (en) 2005-11-04 2011-04-26 Cargill, Incorporated Lecithin-starches compositions, preparation thereof and paper products having oil and grease resistance, and/or release properties

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH604490A5 (fr) * 1970-09-05 1978-09-15 Green Cross Corp
US3958014A (en) * 1970-09-05 1976-05-18 The Green Cross Corporation Process for preparing injection-purpose fluorocarbon emulsion capable of carrying oxygen
JPS5331209B2 (fr) * 1973-10-05 1978-09-01
FR2249657B1 (fr) * 1973-11-07 1977-04-15 Ugine Kuhlmann
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
GB1578776A (en) * 1976-06-10 1980-11-12 Univ Illinois Hemoglobin liposome and method of making the same
US4105798A (en) * 1976-07-19 1978-08-08 Sun Ventures, Inc. Perfluoro polycyclic compounds for use as synthetic blood and perfusion media
US4186253A (en) * 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
US4252827A (en) * 1979-05-23 1981-02-24 The Green Cross Corporation Oxygen-transferable fluorocarbon emulsion
AR220263A1 (es) * 1980-02-19 1980-10-15 Bago Lab Sa Procedimiento para obtener una preparacion inyectable de sulfonamida potenciada de baja irritabilidad

Also Published As

Publication number Publication date
CA1201655A (fr) 1986-03-11
GB8318541D0 (en) 1983-08-10
SE8304144L (sv) 1984-01-28
FR2531857A1 (fr) 1984-02-24
SE8304144D0 (sv) 1983-07-26
DE3326900A1 (de) 1984-02-16
GB2124079A (en) 1984-02-15
US4397870A (en) 1983-08-09
GB2124079B (en) 1987-02-04

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Legal Events

Date Code Title Description
ST Notification of lapse