FR2495154B1 - 5'-aminoalkyl-4', 4, 8-trialkylpsoralenes, leur procede de production et composition pharmaceutique les contenant - Google Patents

5'-aminoalkyl-4', 4, 8-trialkylpsoralenes, leur procede de production et composition pharmaceutique les contenant

Info

Publication number
FR2495154B1
FR2495154B1 FR8114749A FR8114749A FR2495154B1 FR 2495154 B1 FR2495154 B1 FR 2495154B1 FR 8114749 A FR8114749 A FR 8114749A FR 8114749 A FR8114749 A FR 8114749A FR 2495154 B1 FR2495154 B1 FR 2495154B1
Authority
FR
France
Prior art keywords
trialkylpsoralenes
aminoalkyl
pharmaceutical composition
composition containing
production process
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8114749A
Other languages
English (en)
Other versions
FR2495154A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elder Pharmaceuticals Inc
Original Assignee
Elder Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elder Pharmaceuticals Inc filed Critical Elder Pharmaceuticals Inc
Publication of FR2495154A1 publication Critical patent/FR2495154A1/fr
Application granted granted Critical
Publication of FR2495154B1 publication Critical patent/FR2495154B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR8114749A 1980-07-29 1981-07-29 5'-aminoalkyl-4', 4, 8-trialkylpsoralenes, leur procede de production et composition pharmaceutique les contenant Expired FR2495154B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/173,437 US4294822A (en) 1980-07-29 1980-07-29 5-Aminoalkyl-4,4,8-trialkylpsoralens

Publications (2)

Publication Number Publication Date
FR2495154A1 FR2495154A1 (fr) 1982-06-04
FR2495154B1 true FR2495154B1 (fr) 1985-06-28

Family

ID=22632020

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8114749A Expired FR2495154B1 (fr) 1980-07-29 1981-07-29 5'-aminoalkyl-4', 4, 8-trialkylpsoralenes, leur procede de production et composition pharmaceutique les contenant

Country Status (6)

Country Link
US (1) US4294822A (fr)
JP (1) JPS5753490A (fr)
CA (1) CA1158251A (fr)
DE (1) DE3129750A1 (fr)
FR (1) FR2495154B1 (fr)
GB (1) GB2080806B (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950770A (en) * 1987-06-16 1990-08-21 Elder Pharmaceuticals, Inc. Psoralens aminomethylation
US5216176A (en) * 1989-01-23 1993-06-01 Lehigh University 7-alkoxycoumarins, dihydropsoralens, and benzodipyranones as photo-activated therapeutic agents and inhibitors of epidermal growth factor
US5356929A (en) * 1989-01-23 1994-10-18 Lehigh University Reduced and quaternized psoralens as photo-activated therapeutics
US5556958A (en) * 1989-10-26 1996-09-17 Steritech, Inc. Inactivation of pathogens in clinical samples
CA2066234C (fr) * 1989-10-26 2001-04-03 Stephen T. Isaacs Composes et methodes d'activation pour la sterilisation des acides nucleiques
US5116864A (en) * 1991-04-09 1992-05-26 Indiana University Foundation Method for preventing restenosis following reconfiguration of body vessels
WO1994020090A1 (fr) * 1993-03-17 1994-09-15 Steritech, Inc. Decontamination de prelevements cliniques
US5871900A (en) * 1993-06-28 1999-02-16 Cerus Corporation Method of inactivating pathogens in biological fluids using photoactivated 5-primaryamino psoralens
US5712085A (en) 1993-06-28 1998-01-27 Cerus Corporation 5'-(4-amino-2-oxa)butye-4,4', 8-trinethylpsoralen in synthetic medium
US6004741A (en) * 1993-06-28 1999-12-21 Cerus Corporation Method for the photoactivation of 4' and 5' primary aminoalkyl psoralens in platelet preparations
US6420570B1 (en) 1993-06-28 2002-07-16 Cerus Corporation Psoralen compounds
US5399719A (en) * 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US5593823A (en) * 1993-06-28 1997-01-14 Cerus Corporation Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens
US6004742A (en) * 1993-06-28 1999-12-21 Cerus Corporation Method for inactivation of pathogens in platelets using 4' and 5' primary amino-substituted psoralens
US5691132A (en) * 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
US5663043A (en) * 1995-01-04 1997-09-02 Hemasure Inc. Method for inactivating non-enveloped viruses using a viricide-potentiating agent with a photoactivatible virucide
US6177441B1 (en) 1995-06-05 2001-01-23 Cerus Corporation Treating red blood cell solutions with anti-viral agents
US20020115585A1 (en) * 1996-06-07 2002-08-22 Hei Derek J. Method and devices for the removal of psoralens from blood products
US6133460A (en) 1997-11-20 2000-10-17 Cerus Corporation Psoralens for pathogen inactivation
US6255324B1 (en) 1998-11-25 2001-07-03 Ned D. Heindel Amino-and mercurio-substituted 4′,5'-dihydropsoralens and therapeutical uses thereof
US6177424B1 (en) 1998-11-30 2001-01-23 Ned D. Heindel 4′-Substituted-4′,5′-dihydropsoralens and therapeutical uses thereof
FR2803849B1 (fr) * 2000-01-19 2002-04-19 Centre Nat Rech Scient Molecules chimeres formees de psoralene et de retinoide, leur procede de preparation, et leurs applications au traitement de pathologies de l'hyperproliferation cellulaire et notamment du psoriasis
US8071642B2 (en) * 2007-06-28 2011-12-06 Rutgers, The State University Of New Jersey Dimethyl amino ethyl ether psoralens and methods for their production and use
EP3157519B1 (fr) * 2014-06-19 2021-05-12 Immunolight, LLC Procédés et systèmes pour traiter des troubles liés à la prolifération cellulaire avec des dérivés du psoralène

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169204A (en) * 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US4124598A (en) * 1976-10-20 1978-11-07 Hoffmann-La Roche Inc. Psoralens
US4298614A (en) * 1979-09-10 1981-11-03 Thomas C. Elder, Inc. 5'-Aminoalkyl-4',4-dialkylpsoralens

Also Published As

Publication number Publication date
CA1158251A (fr) 1983-12-06
JPS621952B2 (fr) 1987-01-16
FR2495154A1 (fr) 1982-06-04
JPS5753490A (en) 1982-03-30
US4294822A (en) 1981-10-13
DE3129750A1 (de) 1982-03-18
GB2080806A (en) 1982-02-10
GB2080806B (en) 1984-07-25

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ST Notification of lapse