FR2442819A1 - Alcools b,g-dihydropolyprenyliques, leur procede de preparation et leurs applications therapeutiques - Google Patents

Alcools b,g-dihydropolyprenyliques, leur procede de preparation et leurs applications therapeutiques

Info

Publication number
FR2442819A1
FR2442819A1 FR7929508A FR7929508A FR2442819A1 FR 2442819 A1 FR2442819 A1 FR 2442819A1 FR 7929508 A FR7929508 A FR 7929508A FR 7929508 A FR7929508 A FR 7929508A FR 2442819 A1 FR2442819 A1 FR 2442819A1
Authority
FR
France
Prior art keywords
alcohols
dihydropolyprenylics
preparation process
therapeutic applications
dihydropolyprenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7929508A
Other languages
English (en)
Other versions
FR2442819B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FR2442819A1 publication Critical patent/FR2442819A1/fr
Application granted granted Critical
Publication of FR2442819B1 publication Critical patent/FR2442819B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/02—Acyclic alcohols with carbon-to-carbon double bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/08—Preparation of carboxylic acids or their salts, halides or anhydrides from nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention a pour objet des alcools beta , gamma -dihydropolyprényliques répondant à la formule générale :
FR7929508A 1978-12-01 1979-11-30 Alcools b,g-dihydropolyprenyliques, leur procede de preparation et leurs applications therapeutiques Expired FR2442819B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP53147858A JPS6058209B2 (ja) 1978-12-01 1978-12-01 β，γ−ジヒドロポリプレニルアルコ−ルおよびそれからなる血圧降下剤

Publications (2)

Publication Number Publication Date
FR2442819A1 true FR2442819A1 (fr) 1980-06-27
FR2442819B1 FR2442819B1 (fr) 1985-12-27

Family

ID=15439838

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7929508A Expired FR2442819B1 (fr) 1978-12-01 1979-11-30 Alcools b,g-dihydropolyprenyliques, leur procede de preparation et leurs applications therapeutiques

Country Status (11)

Country Link
US (1) US4325974A (fr)
JP (1) JPS6058209B2 (fr)
CA (1) CA1120500A (fr)
CH (1) CH641347A5 (fr)
DE (1) DE2947624A1 (fr)
ES (1) ES486515A0 (fr)
FR (1) FR2442819B1 (fr)
GB (1) GB2038818B (fr)
IT (1) IT1126443B (fr)
NL (1) NL7908705A (fr)
SE (1) SE444931B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054753A1 (fr) * 1980-11-28 1982-06-30 Kuraray Co., Ltd. Composition et composés de polyprényle et procédé pour leur préparation
FR2527597A1 (fr) * 1982-05-28 1983-12-02 Eisai Co Ltd Derives d'alcool b,g-dihydropolyprenylique et composition pharmaceutique contenant un compose polyprenylique
EP0119500A2 (fr) * 1983-02-21 1984-09-26 Nisshin Flour Milling Co., Ltd. Dérivés d'amide de l'acide isoprénique, procédés de leur préparation et compositions pharmaceutiques les contenant

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0041235B1 (fr) * 1980-05-30 1985-02-13 Eisai Co., Ltd. Dérivés alpha, bêta-dihydropolyprényliques pour le traitement des maladies du foie
JPS58167555A (ja) * 1982-03-29 1983-10-03 Kuraray Co Ltd ポリプレニル化合物
US5658958A (en) * 1982-05-28 1997-08-19 Eisai Co., Ltd. β, γ-dihydropolyprenyl alcohol derivatives effective at mitigating stress in animals
US5280048A (en) * 1982-05-28 1994-01-18 Eisai Co., Ltd. β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound
GB2159709B (en) * 1982-05-28 1987-04-08 Eisai Co Ltd Containing a polyprenyl compound
JPS60136510A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 肝疾患治療・予防剤
EP0149847A3 (fr) * 1983-12-26 1989-11-08 Eisai Co., Ltd. Agent thérapeutique et préventif contenant le dolichol
JPS60136512A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 脂質代謝改善剤
JPS60136511A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 高尿酸血症治療剤
JPS60136513A (ja) * 1983-12-26 1985-07-20 Eisai Co Ltd 糖尿病治療剤
CA2269680A1 (fr) * 1996-12-12 1998-06-18 Pharmacia & Upjohn Company Composition huileuse a base de dihydropolyprenols

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2041421A5 (en) * 1969-04-23 1971-01-29 Inst Francais Du Petrole Tetramethyl dinitriles prepn
US3971827A (en) * 1974-09-09 1976-07-27 G. D. Searle & Co. Manufacture of poly-(cis)-isoprenols

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL252912A (fr) * 1959-06-23
US3449407A (en) * 1966-01-11 1969-06-10 Int Flavors & Fragrances Inc Lactic acid esters of polyisoprenoid alcohols
GB1420886A (en) * 1973-01-31 1976-01-14 Teikoku Chem Ind Co Ltd Preparation of polyene compounds and intermediates for the use therein
US3845108A (en) * 1973-08-31 1974-10-29 W Roelofs Trans-7-cis-9-dodecadien-1-yl acetate
US3953532A (en) * 1974-04-25 1976-04-27 Zoecon Corporation 4,8-Tridecadien-1-ol,4 cis,8 cis,trans
JPS5826327B2 (ja) 1974-11-22 1983-06-02 エ−ザイ カブシキガイシヤ ホコウソキユウルイノ ゴウセイホウ
US3985814A (en) * 1975-02-28 1976-10-12 Celanese Corporation Production of alcohols from carboxylic acids
US4198532A (en) * 1977-08-04 1980-04-15 Givaudan Corporation Novel alcohol odorants

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2041421A5 (en) * 1969-04-23 1971-01-29 Inst Francais Du Petrole Tetramethyl dinitriles prepn
US3971827A (en) * 1974-09-09 1976-07-27 G. D. Searle & Co. Manufacture of poly-(cis)-isoprenols

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ABJP/70 *
CA1963 *
CA1967 *
CA1972 *
CA1978 *
EXBK/76 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0054753A1 (fr) * 1980-11-28 1982-06-30 Kuraray Co., Ltd. Composition et composés de polyprényle et procédé pour leur préparation
FR2527597A1 (fr) * 1982-05-28 1983-12-02 Eisai Co Ltd Derives d'alcool b,g-dihydropolyprenylique et composition pharmaceutique contenant un compose polyprenylique
FR2532844A1 (fr) * 1982-05-28 1984-03-16 Eisai Co Ltd Composition pharmaceutique contenant un compose polyprenylique
FR2569108A1 (fr) * 1982-05-28 1986-02-21 Eisai Co Ltd Composition pharmaceutique contenant un compose polyprenylique
EP0119500A2 (fr) * 1983-02-21 1984-09-26 Nisshin Flour Milling Co., Ltd. Dérivés d'amide de l'acide isoprénique, procédés de leur préparation et compositions pharmaceutiques les contenant
EP0119500A3 (en) * 1983-02-21 1985-01-16 Nisshin Flour Milling Co., Ltd. Novel isoprenylic acid amide derivatives, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS6058209B2 (ja) 1985-12-19
SE7909916L (sv) 1980-06-02
CA1120500A (fr) 1982-03-23
IT7927750A0 (it) 1979-11-30
DE2947624A1 (de) 1980-06-12
SE444931B (sv) 1986-05-20
NL7908705A (nl) 1980-06-03
US4325974A (en) 1982-04-20
ES8101530A1 (es) 1980-12-16
ES486515A0 (es) 1980-12-16
JPS5576829A (en) 1980-06-10
FR2442819B1 (fr) 1985-12-27
GB2038818A (en) 1980-07-30
GB2038818B (en) 1983-02-16
CH641347A5 (fr) 1984-02-29
IT1126443B (it) 1986-05-21

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Legal Events

Date Code Title Description
ST Notification of lapse