FR2422657A1 - 2-(2-thenoylthio)-propionylglycine, procede pour sa preparation et compositions pharmaceutiques la contenant - Google Patents

2-(2-thenoylthio)-propionylglycine, procede pour sa preparation et compositions pharmaceutiques la contenant

Info

Publication number
FR2422657A1
FR2422657A1 FR7907633A FR7907633A FR2422657A1 FR 2422657 A1 FR2422657 A1 FR 2422657A1 FR 7907633 A FR7907633 A FR 7907633A FR 7907633 A FR7907633 A FR 7907633A FR 2422657 A1 FR2422657 A1 FR 2422657A1
Authority
FR
France
Prior art keywords
thenoylthio
propionylglycine
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7907633A
Other languages
English (en)
Other versions
FR2422657B1 (fr
Inventor
Franco Bolasco
Giuseppe Quadro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mediolanum Farmaceutici SpA
Original Assignee
Mediolanum Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22175/78A external-priority patent/IT1095386B/it
Priority claimed from IT2011179A external-priority patent/IT1166627B/it
Application filed by Mediolanum Farmaceutici SpA filed Critical Mediolanum Farmaceutici SpA
Publication of FR2422657A1 publication Critical patent/FR2422657A1/fr
Application granted granted Critical
Publication of FR2422657B1 publication Critical patent/FR2422657B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)

Abstract

a. 2-(2-thénoylthio)-propionylglycine, procédé pour sa préparation et compositions pharmaceutiques la contenant. b. 2-(2-thénoylthio)-propionylglycine de formule :
FR7907633A 1978-04-11 1979-03-27 2-(2-thenoylthio)-propionylglycine, procede pour sa preparation et compositions pharmaceutiques la contenant Granted FR2422657A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22175/78A IT1095386B (it) 1978-04-11 1978-04-11 2-(2-tenciltio)-propionilglicina,metodo per la sua preparazione e composizioni farmaceutiche che la contengono
IT2011179A IT1166627B (it) 1979-02-12 1979-02-12 Impiego della 2-(2-tenoiltio)-propionilglicina in qualita' di agente mucolitico e antibroncospastico

Publications (2)

Publication Number Publication Date
FR2422657A1 true FR2422657A1 (fr) 1979-11-09
FR2422657B1 FR2422657B1 (fr) 1981-10-23

Family

ID=26327401

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7907633A Granted FR2422657A1 (fr) 1978-04-11 1979-03-27 2-(2-thenoylthio)-propionylglycine, procede pour sa preparation et compositions pharmaceutiques la contenant

Country Status (16)

Country Link
US (1) US4242354A (fr)
JP (1) JPS5910673B2 (fr)
AR (1) AR219379A1 (fr)
AT (1) AT374194B (fr)
CA (1) CA1121825A (fr)
CH (1) CH639380A5 (fr)
DE (1) DE2913211C2 (fr)
DK (1) DK148117C (fr)
ES (1) ES479423A1 (fr)
FR (1) FR2422657A1 (fr)
GB (1) GB2018756B (fr)
IE (1) IE47946B1 (fr)
LU (1) LU81132A1 (fr)
NL (1) NL7902700A (fr)
NO (1) NO149312C (fr)
SE (1) SE444940B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2483419A1 (fr) * 1980-06-03 1981-12-04 Btb Ind Chimica Procede de preparation de la n-(2-(2-thenoyl)-thiopropionyl)-glicine
FR2508907A1 (fr) * 1981-07-02 1983-01-07 Sigma Tau Ind Farmaceuti Esters d'hydroxybenzenes substitues de 2-thenoylmercaptopropionylglycine utiles notamment comme mucolytiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1148890B (it) * 1980-07-22 1986-12-03 Neopharmed Spa Derivato della teonil tiopropionil glicina e procedimento per la sua preparazione
US4415681A (en) * 1980-10-23 1983-11-15 Ford Motor Company Stabilized crosslinked dispersion
FR2502627A1 (fr) 1981-02-02 1982-10-01 Refarmed Sa Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation et produits pharmaceutiques dans lesquels ils apparaissent
IE52884B1 (en) * 1981-05-11 1988-03-30 Sigma Tau Ind Farmaceuti 2-methoxyphenyl esters of n-substituted amino acids, their preparation and pharmaceutical use
FR2521146B1 (fr) * 1983-02-02 1985-10-25 Sigma Tau Ind Farmaceuti Derives thioliques de l'erythromycine a activite therapeutique, procede de preparation, et produits pharmaceutiques dans lesquels ils apparaissent
IT1212723B (it) * 1983-03-23 1989-11-30 Medea Res Srl Derivato dell'acido tiolattico ad attivita'broncosecretogoga.
JPS59191971U (ja) * 1983-06-08 1984-12-20 有限会社　沢田久商店 枕
JPS60152786U (ja) * 1984-03-21 1985-10-11 三協アルミニウム工業株式会社 サツシ枠取外し装置
US4595700A (en) * 1984-12-21 1986-06-17 G. D. Searle & Co. Thiol based collagenase inhibitors
ES2039260T3 (es) * 1987-02-05 1993-09-16 Farmaceutici Caber S.P.A. Derivado de 4-oxo-1,3-benzodioxano.
JPS63199669U (fr) * 1987-05-22 1988-12-22
US6192882B1 (en) * 1997-02-24 2001-02-27 Aradigm Corporation Formulation and devices for monitoring the efficacy of the delivery of aerosols
US6349719B2 (en) 1997-02-24 2002-02-26 Aradigm Corporation Formulation and devices for monitoring the efficacy of the delivery of aerosols
TWI625121B (zh) 2009-07-13 2018-06-01 基利科學股份有限公司 調節細胞凋亡信號之激酶的抑制劑
CA2802743C (fr) * 2010-07-02 2019-05-07 Gilead Sciences, Inc. Inhibiteurs des kinases regulant les signaux de l'apoptose
CN106008456A (zh) * 2016-06-27 2016-10-12 山东川成医药股份有限公司 一种司替罗宁的制备方法
US20240254098A1 (en) * 2021-05-10 2024-08-01 Altibio, Inc. Thioester prodrugs for the treatment of renal anomalies

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338701A1 (fr) * 1976-01-23 1977-08-19 Blum Jean Nouveaux derives de la cysteine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2510773A (en) * 1946-05-18 1950-06-06 Sterling Drug Inc Process for preparing a tertiary amino-alkyl thiol-ester hydrochloride
US2632735A (en) * 1951-03-01 1953-03-24 Standard Oil Dev Co Lubricating oil additives
US2669564A (en) * 1951-03-17 1954-02-16 Sterling Drug Inc Tertiary-aminoalkyl 4-amino-2-alkoxy-thiolbenzoates and their preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338701A1 (fr) * 1976-01-23 1977-08-19 Blum Jean Nouveaux derives de la cysteine

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2483419A1 (fr) * 1980-06-03 1981-12-04 Btb Ind Chimica Procede de preparation de la n-(2-(2-thenoyl)-thiopropionyl)-glicine
FR2508907A1 (fr) * 1981-07-02 1983-01-07 Sigma Tau Ind Farmaceuti Esters d'hydroxybenzenes substitues de 2-thenoylmercaptopropionylglycine utiles notamment comme mucolytiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
GB2018756B (en) 1982-10-13
DE2913211A1 (de) 1979-10-25
CH639380A5 (it) 1983-11-15
FR2422657B1 (fr) 1981-10-23
ES479423A1 (es) 1979-11-01
LU81132A1 (fr) 1979-06-19
GB2018756A (en) 1979-10-24
NO149312C (no) 1984-03-28
DE2913211C2 (de) 1982-05-06
DK148117B (da) 1985-03-11
JPS54141761A (en) 1979-11-05
SE444940B (sv) 1986-05-20
NO791205L (no) 1979-10-12
NO149312B (no) 1983-12-19
AT374194B (de) 1984-03-26
DK148117C (da) 1985-08-26
AR219379A1 (es) 1980-08-15
SE7903105L (sv) 1979-10-12
JPS5910673B2 (ja) 1984-03-10
DK153179A (da) 1979-10-12
IE47946B1 (en) 1984-07-25
IE790788L (en) 1979-10-11
US4242354A (en) 1980-12-30
NL7902700A (nl) 1979-10-15
ATA249879A (de) 1983-08-15
CA1121825A (fr) 1982-04-13

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