FR2372817A1 - DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS - Google Patents

DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS

Info

Publication number
FR2372817A1
FR2372817A1 FR7735940A FR7735940A FR2372817A1 FR 2372817 A1 FR2372817 A1 FR 2372817A1 FR 7735940 A FR7735940 A FR 7735940A FR 7735940 A FR7735940 A FR 7735940A FR 2372817 A1 FR2372817 A1 FR 2372817A1
Authority
FR
France
Prior art keywords
acids
derivatives
useful
thiazolidinecarboxylic
hypertension agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735940A
Other languages
French (fr)
Other versions
FR2372817B1 (en
Inventor
Miguel Angel Ondetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2372817A1 publication Critical patent/FR2372817A1/en
Application granted granted Critical
Publication of FR2372817B1 publication Critical patent/FR2372817B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne de nouveaux dérivés substitués d'acides thiazolidine-carboxyliques, thiazane-carboxyliques et d'acides carboxyliques apparentés de formule générale :The invention relates to novel substituted derivatives of thiazolidine-carboxylic, thiazane-carboxylic and related carboxylic acids of general formula:

FR7735940A 1976-12-03 1977-11-29 DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS Granted FR2372817A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74728176A 1976-12-03 1976-12-03
US83610777A 1977-09-23 1977-09-23

Publications (2)

Publication Number Publication Date
FR2372817A1 true FR2372817A1 (en) 1978-06-30
FR2372817B1 FR2372817B1 (en) 1981-06-19

Family

ID=27114718

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7735940A Granted FR2372817A1 (en) 1976-12-03 1977-11-29 DERIVATIVES OF THIAZOLIDINECARBOXYLIC ACIDS AND RELATED ACIDS, USEFUL AS ANTI-HYPERTENSION AGENTS

Country Status (28)

Country Link
JP (1) JPS5382778A (en)
AR (1) AR220689A1 (en)
AT (1) AT363467B (en)
AU (1) AU518147B2 (en)
BG (1) BG32269A3 (en)
CA (1) CA1146940A (en)
CH (1) CH634062A5 (en)
DD (1) DD133798A5 (en)
DE (1) DE2752719C2 (en)
DK (1) DK152494C (en)
EG (1) EG13037A (en)
ES (1) ES464555A1 (en)
FI (1) FI67378C (en)
FR (1) FR2372817A1 (en)
GB (1) GB1578940A (en)
GR (1) GR72453B (en)
HK (1) HK55881A (en)
IE (1) IE46169B1 (en)
IL (1) IL53352A0 (en)
IN (1) IN146945B (en)
IT (1) IT1092179B (en)
NL (3) NL171055C (en)
NO (1) NO148416C (en)
NZ (1) NZ185800A (en)
PT (1) PT67352B (en)
RO (2) RO72596A (en)
SE (1) SE441267B (en)
YU (1) YU41823B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2395998A1 (en) * 1977-06-29 1979-01-26 Yoshitomi Pharmaceutical NEW THIAZOLIDINE DERIVATIVES AND THEIR APPLICATION IN THE TREATMENT OF HYPERTENSION
FR2421889A1 (en) * 1978-04-08 1979-11-02 Santen Pharmaceutical Co Ltd NEW DERIVATIVES OF THIAZOLIDINECARBOXYLIC-4 ACID USEFUL AS ANTIHYPERTENSIVE MEDICINAL PRODUCTS AND METHODS FOR THEIR PREPARATION
FR2434150A1 (en) * 1978-08-24 1980-03-21 Yoshitomi Pharmaceutical HYDROXAMIC ACID DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT
FR2438036A1 (en) * 1978-10-05 1980-04-30 Yoshitomi Pharmaceutical DERIVATIVES OF CYCLIC IMINOCARBOXYLIC ACIDS AND MEDICAMENT CONTAINING THESE SUBSTANCES
FR2445324A1 (en) * 1978-12-30 1980-07-25 Santen Pharmaceutical Co Ltd NOVEL DISULFIDE DERIVATIVES CONTAINING A PYRROLIDINE OR THIAZOLIDINE CYCLE USEFUL AS ANTIHYPERTENSORS AND FOR PREVENTING AND TREATING DIABETES COMPLICATIONS AND METHODS FOR THEIR PREPARATION

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455565A (en) * 1977-10-06 1979-05-02 Santen Pharmaceut Co Ltd Novel thiazolidine derivative
JPS557255A (en) * 1978-07-03 1980-01-19 Santen Pharmaceut Co Ltd Thiazolidine derivative
GR73585B (en) * 1978-09-11 1984-03-26 Univ Miami
JPS5540622A (en) * 1978-09-14 1980-03-22 Santen Pharmaceut Co Ltd Hypotensive agent
US4483861A (en) * 1978-10-31 1984-11-20 Santen Pharmaceutical Co., Ltd. Antihypertensive sulfur-containing compounds
JPS5562060A (en) * 1978-10-31 1980-05-10 Santen Pharmaceut Co Ltd Sulfur-containing compound
JPS55124757A (en) * 1979-03-17 1980-09-26 Santen Pharmaceut Co Ltd Sulfur-containing compound
JPS565415A (en) * 1979-06-26 1981-01-20 Santen Pharmaceut Co Ltd Ester-type hypotensor
JPS5683483A (en) * 1979-12-13 1981-07-08 Santen Pharmaceut Co Ltd Thiazolidine compound
JPS56139455A (en) * 1980-04-02 1981-10-30 Santen Pharmaceut Co Ltd Sulfur-containing acylaminoacid
DE3152643A1 (en) * 1980-12-29 1982-12-16 Santen Pharmaceutical Co Ltd HETEROCYCLIC 5-MEMBERED RING COMPOUNDS
JPH0662529B2 (en) * 1984-07-13 1994-08-17 三共株式会社 Amino acid derivative
AU584668B2 (en) * 1985-02-04 1989-06-01 G.D. Searle & Co. Novel heterocyclic amides useful as anti-inflammatory and anti-allergy agents

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2340932A1 (en) * 1976-02-13 1977-09-09 Squibb & Sons Inc PROLINE DERIVATIVES AND RELATED COMPOUNDS USEFUL FOR REDUCING BLOOD TENSION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2446100C3 (en) * 1974-09-26 1982-01-14 Ludwig Merckle Kg Chem. Pharm. Fabrik, 7902 Blaubeuren Phenoxyalkanecarboxamides of thiazolidinecarboxylic acids, process for their preparation and pharmaceuticals

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2340932A1 (en) * 1976-02-13 1977-09-09 Squibb & Sons Inc PROLINE DERIVATIVES AND RELATED COMPOUNDS USEFUL FOR REDUCING BLOOD TENSION

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2395998A1 (en) * 1977-06-29 1979-01-26 Yoshitomi Pharmaceutical NEW THIAZOLIDINE DERIVATIVES AND THEIR APPLICATION IN THE TREATMENT OF HYPERTENSION
FR2421889A1 (en) * 1978-04-08 1979-11-02 Santen Pharmaceutical Co Ltd NEW DERIVATIVES OF THIAZOLIDINECARBOXYLIC-4 ACID USEFUL AS ANTIHYPERTENSIVE MEDICINAL PRODUCTS AND METHODS FOR THEIR PREPARATION
FR2434150A1 (en) * 1978-08-24 1980-03-21 Yoshitomi Pharmaceutical HYDROXAMIC ACID DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT
FR2438036A1 (en) * 1978-10-05 1980-04-30 Yoshitomi Pharmaceutical DERIVATIVES OF CYCLIC IMINOCARBOXYLIC ACIDS AND MEDICAMENT CONTAINING THESE SUBSTANCES
FR2445324A1 (en) * 1978-12-30 1980-07-25 Santen Pharmaceutical Co Ltd NOVEL DISULFIDE DERIVATIVES CONTAINING A PYRROLIDINE OR THIAZOLIDINE CYCLE USEFUL AS ANTIHYPERTENSORS AND FOR PREVENTING AND TREATING DIABETES COMPLICATIONS AND METHODS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
SE7713722L (en) 1978-06-04
IL53352A0 (en) 1978-01-31
YU41823B (en) 1988-02-29
FI67378C (en) 1985-03-11
DE2752719A1 (en) 1978-06-08
CH634062A5 (en) 1983-01-14
AT363467B (en) 1981-08-10
FI773640A (en) 1978-06-04
IE46169L (en) 1978-06-03
PT67352B (en) 1979-05-15
SE441267B (en) 1985-09-23
FR2372817B1 (en) 1981-06-19
NL171055C (en) 1983-02-01
DD133798A5 (en) 1979-01-24
ES464555A1 (en) 1978-09-01
CA1146940A (en) 1983-05-24
FI67378B (en) 1984-11-30
NZ185800A (en) 1980-04-28
GR72453B (en) 1983-11-09
PT67352A (en) 1978-01-01
GB1578940A (en) 1980-11-12
NL8201146A (en) 1982-07-01
HK55881A (en) 1981-11-20
NO774126L (en) 1978-06-06
IT1092179B (en) 1985-07-06
EG13037A (en) 1980-12-31
DK538277A (en) 1978-06-04
DE2752719C2 (en) 1982-03-25
RO72596B (en) 1983-07-30
NL8201145A (en) 1982-07-01
AU3037977A (en) 1979-05-17
ATA857677A (en) 1981-01-15
JPS5382778A (en) 1978-07-21
NO148416B (en) 1983-06-27
AU518147B2 (en) 1981-09-17
NL7713274A (en) 1978-06-06
DK152494C (en) 1988-07-25
JPS618834B2 (en) 1986-03-18
DK152494B (en) 1988-03-07
IN146945B (en) 1979-10-20
BG32269A3 (en) 1982-06-15
RO72596A (en) 1983-08-03
IE46169B1 (en) 1983-03-09
YU283777A (en) 1983-01-21
NO148416C (en) 1983-10-12
RO78013A (en) 1981-12-25
AR220689A1 (en) 1980-11-28

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Legal Events

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