FR2081498B1 - - Google Patents

Info

Publication number: FR2081498B1
Authority: FR; France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR7103970A

Other versions

FR2081498A1 (fr

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Canada Inc

Original Assignee

Ayerst Mckenna and Harrison Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1970-02-10

Filing date

1971-02-05

Publication date

1975-01-17

1971-02-05 Application filed by Ayerst Mckenna and Harrison Inc filed Critical Ayerst Mckenna and Harrison Inc

1971-12-03 Publication of FR2081498A1 publication Critical patent/FR2081498A1/fr

1974-09-30 Priority claimed from US510275A external-priority patent/US3922346A/en

1975-01-17 Application granted granted Critical

1975-01-17 Publication of FR2081498B1 publication Critical patent/FR2081498B1/fr

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FR7103970A 1970-02-10 1971-02-05 Expired FR2081498B1 (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US1030670A	1970-02-10	1970-02-10
US097481A US3914305A (en)	1970-02-10	1970-12-21	N-{8 (10,11-dihydro-5H-dibenzo{8 a,d{9 cyclohepten-5-yl)methyl{9 amides
US510275A US3922346A (en)	1970-02-10	1974-09-30	Benzocycloheptaisoquinoline derivatives III in producing CNS depressant effects

Publications (2)

Publication Number	Publication Date
FR2081498A1 FR2081498A1 (fr)	1971-12-03
FR2081498B1 true FR2081498B1 (fr)	1975-01-17

Family

ID=27359200

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7103970A Expired FR2081498B1 (fr)	1970-02-10	1971-02-05

Country Status (14)

Country	Link
US (2)	US3657250A (fr)
AR (4)	AR195768A1 (fr)
BE (1)	BE762595A (fr)
CA (1)	CA982124A (fr)
CH (3)	CH569716A5 (fr)
CS (1)	CS181207B2 (fr)
DE (1)	DE2106165A1 (fr)
DK (1)	DK139582B (fr)
FI (1)	FI49504C (fr)
FR (1)	FR2081498B1 (fr)
GB (1)	GB1341109A (fr)
NL (1)	NL170733C (fr)
SE (2)	SE401674B (fr)
ZA (1)	ZA71532B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3896130A (en) *	1972-08-04	1975-07-22	Ayerst Mckenna & Harrison	Ocathydrobenzocycloheptapyridoisoquinoline derivatives and process for the preparation thereof
US4062851A (en) *	1975-11-26	1977-12-13	Ayerst Mckenna And Harrison Ltd.	Process for the resolution of certain octahydrobenzocycloheptapyridoisoquinolinols
US4053604A (en) *	1975-11-26	1977-10-11	Ayerst, Mckenna & Harrison Limited	Method for improving anesthesia and compositions therefor
US4059585A (en) *	1976-07-27	1977-11-22	Ayerst Mckenna And Harrison Ltd.	Process for preparing an intermediate for CNS depressants
FR2366839A2 (fr) *	1976-10-08	1978-05-05	Ayerst Mckenna & Harrison	Derives de benzocycloheptane-isoquinoleine
TWI375676B (en) *	2005-08-29	2012-11-01	Msd Oss Bv	Non-steroidal glucocorticoid receptor modulators
US10441573B2 (en)	2015-12-09	2019-10-15	Brandeis University	DBH inhibitors for treating memory loss
CN109970626A (zh) *	2018-12-30	2019-07-05	南京正荣医药化学有限公司	一种2-哌啶酮碱金属盐的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US336175A (en) *		1886-02-16		tompeins
US3052721A (en) *	1961-01-10	1962-09-04	Olin Mathieson	Dihydrodibenzocy cloheptene derivatives
US3403157A (en) *	1965-09-01	1968-09-24	American Home Prod	Benzo[6, 7]cyclohepta[1, 2, 3-d, e]isoquinoline derivatives

1970
- 1970-02-10 US US10306A patent/US3657250A/en not_active Expired - Lifetime
- 1970-12-21 US US097481A patent/US3914305A/en not_active Expired - Lifetime
1971
- 1971-01-27 ZA ZA710532A patent/ZA71532B/xx unknown
- 1971-02-05 FR FR7103970A patent/FR2081498B1/fr not_active Expired
- 1971-02-05 SE SE7101475A patent/SE401674B/xx unknown
- 1971-02-05 BE BE762595A patent/BE762595A/fr not_active IP Right Cessation
- 1971-02-08 CH CH172674A patent/CH569716A5/xx not_active IP Right Cessation
- 1971-02-08 CH CH172574A patent/CH584201A5/xx not_active IP Right Cessation
- 1971-02-08 CH CH182271A patent/CH548395A/fr not_active IP Right Cessation
- 1971-02-09 DK DK57071AA patent/DK139582B/da unknown
- 1971-02-09 FI FI710353A patent/FI49504C/fi active
- 1971-02-09 CS CS7100000935A patent/CS181207B2/cs unknown
- 1971-02-09 CA CA104,933A patent/CA982124A/en not_active Expired
- 1971-02-10 DE DE19712106165 patent/DE2106165A1/de not_active Ceased
- 1971-02-10 AR AR233932A patent/AR195768A1/es active
- 1971-02-10 NL NLAANVRAGE7101752,A patent/NL170733C/xx active
- 1971-04-19 GB GB2142771A patent/GB1341109A/en not_active Expired
- 1971-12-01 AR AR239358A patent/AR195786A1/es active
- 1971-12-01 AR AR239357A patent/AR195785A1/es active
1972
- 1972-01-01 AR AR245635A patent/AR206589A1/es active
1973
- 1973-11-14 SE SE7315436A patent/SE406195B/xx unknown

Also Published As

Publication number	Publication date
CA982124A (en)	1976-01-20
CH569716A5 (fr)	1975-11-28
BE762595A (fr)	1971-08-05
AR206589A1 (es)	1976-08-06
DK139582C (fr)	1979-09-03
CS181207B2 (en)	1978-03-31
DE2106165A1 (de)	1971-08-19
US3657250A (en)	1972-04-18
AR195785A1 (es)	1973-11-09
AR195786A1 (es)	1973-11-09
SE401674B (sv)	1978-05-22
CH584201A5 (fr)	1977-01-31
FI49504B (fr)	1975-04-01
CH548395A (fr)	1974-04-30
AR195768A1 (es)	1973-11-09
NL170733B (nl)	1982-07-16
FR2081498A1 (fr)	1971-12-03
NL170733C (nl)	1982-12-16
GB1341109A (en)	1973-12-19
NL7101752A (fr)	1971-08-12
US3914305A (en)	1975-10-21
DK139582B (da)	1979-03-12
FI49504C (fi)	1975-07-10
ZA71532B (en)	1972-07-26
SE406195B (sv)	1979-01-29

Legal Events

Date	Code	Title	Description
1984-12-21	ST	Notification of lapse

Publication	Publication Date	Title
FR2081498B1 (fr)	1975-01-17
ATA96471A (fr)	1973-02-15
AU2044470A (fr)	1972-03-30
AU1473870A (fr)	1971-11-11
AU1833270A (fr)	1972-02-10
AU2017870A (fr)	1972-03-23
AU2085370A (fr)	1972-04-13
AU2130570A (fr)	1972-04-27
AU1716970A (fr)	1972-01-06
AU1517670A (fr)	1971-11-18
AU1336970A (fr)	1971-10-07
AU1326870A (fr)	1971-10-28
AU2115870A (fr)	1972-04-20
AU1918570A (fr)	1972-03-02
AU1841070A (fr)	1972-02-10
AU2131570A (fr)	1972-04-27
AU2130770A (fr)	1972-04-27
AU1328670A (fr)	1971-10-07
AU1343870A (fr)	1971-10-07
AU2119370A (fr)	1972-04-20
AU1832970A (fr)	1972-02-03
AU2112570A (fr)	1972-04-20
ATA672271A (fr)	1973-12-15
AU2061170A (fr)	1972-04-13
AU1581370A (fr)	1971-12-09